IP Verse

Novel Tnf Structure For Use In Therapy - EP3311168

The patent EP3311168 was granted to UCB Biopharma on May 10, 2023. The application was originally filed on Oct 22, 2015 under application number EP15784067A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3311168

UCB BIOPHARMA
Application Number
EP15784067A
Filing Date
Oct 22, 2015
Status
Granted And Under Opposition
Apr 7, 2023
Grant Date
May 10, 2023
External Links
Slate, Register, Google Patents

Patent Summary

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Patent Family

Patent Oppositions (2)

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DR H ULRICH DORRIESFeb 12, 2024DORRIESADMISSIBLE
DR H ULRICH DORRIESFeb 12, 2024DORRIES, HANS ULRICH , DF-MP DORRIES FRANK-MOLNIA & POHLMANADMISSIBLE

Patent Citations (14) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
INTERNATIONAL-SEARCH-REPORTUS2002110868
INTERNATIONAL-SEARCH-REPORTUS7993636
INTERNATIONAL-SEARCH-REPORTWO2013186229
INTERNATIONAL-SEARCH-REPORTWO2014009295
OPPOSITIONUS2002110868
OPPOSITIONUS7993636
OPPOSITIONWO2013186229
OPPOSITIONWO2014009295
OPPOSITIONWO2014009296
OPPOSITIONWO2015086525
OPPOSITIONWO2015086526
OPPOSITIONWO2015086527
OPPOSITIONWO2016149436
OPPOSITIONWO2016168633

Non-Patent Literature (NPL) Citations (14) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
EXAMINATION- S S Cha ET AL, "High Resolution Crystal Structure of a Human Tumor Necrosis Factor-[alpha] Mutant with Low Systemic Toxicity", The Journal of biological chemistry, United States, doi:10.1074/jbc.273.4.2153, (19980123), pages 2153 - 2160, URL: http://www.jbc.org/content/273/4/2153.full.pdf, XP055572909
EXAMINATION- MUKAI YOHEI ET AL, "Solution of the structure of the TNF-TNFR2 complex", vol. 3, no. 148, doi:10.1126/SCISIGNAL.2000954, ISSN 1525-8882, (20101116), page ra83, STKE: SIGNAL TRANSDUCTION KNOWLEDGE ENVIRONMENT, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, URL: http://stke.sciencemag.org/cgi/doi/10.1126/scisignal.2000954, XP009512083
OPPOSITION- Amie Boal, "X-ray crystallography", 2014 Penn State Bioinorganic Workshop, (20140531), pages 1 - 89, XP093162371
OPPOSITION- Choi, H. ; Lee, Y. ; Park, H. ; Oh, D.S., "Discovery of the inhibitors of tumor necrosis factor alpha with structure-based virtual screening", Bioorganic & Medicinal Chemistry Letters, ELSEVIER, Amsterdam NL, Amsterdam NL , (20101101), vol. 20, no. 21, ISSN 0960-894X, pages 6195 - 6198, XP027403962
OPPOSITION- Ecks Michael J, Sprang Stephen R, "The Structure of Tumor Necrosis Factor-cr at 2.6 A Resolution", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (19891015), vol. 264, no. 29, pages 17595 - 17605, XP055231028
OPPOSITION- Grazioli, L. ; Alzani, R. ; Ciomei, M. ; Mariani, M. ; Restivo, A. ; Cozzi, E. ; Marcucci, F., "Inhibitory effect of suramin on receptor binding and cytotoxic activity of tumor necrosis factor a", INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, ELMSFORD,NY, US, US , (19920501), vol. 14, no. 4, doi:10.1016/0192-0561(92)90125-5, ISSN 0192-0561, pages 637 - 642, XP023823826
OPPOSITION- Dirk Brenner, "Regulation of tumour necrosis factor signalling: live or let die", Nature Reviews Immunology, Nature Publishing Group UK, London, London, (20150601), vol. 15, no. 6, doi:10.1038/nri3834, ISSN 1474-1733, pages 362 - 374, XP093162333
OPPOSITION- S S Cha, J S Kim, H S Cho, N K Shin, W Jeong, H C Shin, Y J Kim, J H Hahn, B H Oh, "High Resolution Crystal Structure of a Human Tumor Necrosis Factor-α Mutant with Low Systemic Toxicity", The Journal of biological chemistry, United States, United States , (19980123), vol. 273, no. 4, doi:10.1074/jbc.273.4.2153, pages 2153 - 2160, XP055572909
OPPOSITION- L. Ma, H. Gong, H. Zhu, Q. Ji, P. Su, P. Liu, S. Cao, J. Yao, L. Jiang, M. Han, X. Ma, D. Xiong, H. R. Luo, F. Wang, J. Zhou, Y. Xu, "A Novel Small-molecule Tumor Necrosis Factor   Inhibitor Attenuates Inflammation in a Hepatitis Mouse Model", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (20140502), vol. 289, no. 18, doi:10.1074/jbc.M113.521708, ISSN 0021-9258, pages 12457 - 12466, XP055231855
OPPOSITION- David J. Watkin, "Chemical crystallography-science, technology or a black art", CRYSTALLOGRAPHY REVIEWS, TAYLOR & FRANCIS LTD.,, GB, GB , (20100701), vol. 16, no. 3, doi:10.1080/08893110903483246, ISSN 0889-311X, pages 197 - 230, XP093162342
OPPOSITION- Molly M. He, Annemarie Stroustrup Smith, Johan D. Oslob, William M. Flanagan, Andrew C. Braisted, Adrian Whitty, Mark T. Cancilla, Jun Wang, Alexey A. Lugovskoy, Josh C. Yoburn, Amy D. Fung, Graham Farrington, John K. Eldredge, Eric S. Day, Leslie A. Cruz, Teresa G. Cachero, Stephan K. Miller, Jessica E. Friedman, Ingrid C. Choong, and Brian C. Cunningham, "Small-Molecule Inhibition of TNF-alpha", Science, American Association for the Advancement of Science, US, US , (20051111), vol. 310, no. 5750, doi:10.1126/science.1116304, ISSN 0036-8075, pages 1022 - 1025, XP008147896
OPPOSITION- Mukai Yohei; Nakamura Teruya; Yoshikawa Mai; Yoshioka Yasuo; Tsunoda Shin-ichi; Nakagawa Shinsaku; Yamagata Yuriko; Tsutsumi Yasuo, "Solution of the structure of the TNF-TNFR2 complex.", STKE: SIGNAL TRANSDUCTION KNOWLEDGE ENVIRONMENT, American Association for the Advancement of Science, US, US , (20101116), vol. 3, no. 148, doi:10.1126/scisignal.2000954, ISSN 1525-8882, pages ra83 - ra83, XP009512083
OPPOSITION- Victoria Richmond, "Small Molecules as Anti-TNF Drugs", Current medicinal chemistry, Bentham, NL, NL , (20150829), vol. 22, no. 25, doi:10.2174/0929867322666150729115553, ISSN 0929-8673, pages 2920 - 2942, XP093162339
OPPOSITION- Jessica M Davis, "Small-molecule inhibitors of the interaction between TNF and TNFR", Future Medicinal Chemistry, Future Science Ltd., GB, GB , (20130101), vol. 5, no. 1, doi:10.4155/fmc.12.192, ISSN 1756-8919, pages 69 - 79, XP093162336

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