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Improved Process For The Production Of Fucosylated Oligosaccharides - EP3315610

The patent EP3315610 was granted to CHR Hansen HMO on Dec 16, 2020. The application was originally filed on Oct 29, 2016 under application number EP16196486A. The patent is currently recorded with a legal status of "Revoked".

EP3315610

CHR HANSEN HMO
Application Number
EP16196486A
Filing Date
Oct 29, 2016
Status
Revoked
Mar 5, 2025
Grant Date
Dec 16, 2020
External Links
Slate, Register, Google Patents

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Patent Citations (19) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONEP1927316
DESCRIPTIONEP2439264
DESCRIPTIONEP2479263
DESCRIPTIONEP3050973
DESCRIPTIONUS2014120611
DESCRIPTIONWO2010142305
EXAMINATIONWO2012007481
EXAMINATIONWO2013087884
EXAMINATIONWO2016075243
OPPOSITIONEP3315610
OPPOSITIONUS2013122553
OPPOSITIONUS2015240277
OPPOSITIONUS2016186223
OPPOSITIONWO2010142305
OPPOSITIONWO2013087884
OPPOSITIONWO2014018596
OPPOSITIONWO2015197082
SEARCHWO2010070104
SEARCHWO2016153300

Non-Patent Literature (NPL) Citations (25) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- LAMBERT, BONGERS ET AL., "Cre-lox-based system for multiple gene deletions and selectable-marker removal in Lactobacillus plantarum", APPL. ENVIRON. MICROBIAL., (2007), vol. 73, pages 1126 - 113-
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DESCRIPTION- KOVACH, ELZER ET AL., "Four new derivatives of the broad-host-range cloning vector pBBR1 MCS, carrying different antibiotic-resistance cassettes", GENE, (1995), vol. 166, doi:doi:10.1016/0378-1119(95)00584-1, pages 175 - 176, XP004043131
DESCRIPTION- DATSENKO; WARNER, "One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products", PROC. NATL. ACAD. SCI. USA, (2000), vol. 97, doi:doi:10.1073/pnas.120163297, pages 6640 - 6645, XP002210218
DESCRIPTION- ELLIS ET AL., "High efficiency mutagenesis, repair, and engineering of chromosomal DNA using single-stranded oligonucleotides", PROC. NATL. ACAD. SCI. USA, (2001), vol. 98, doi:doi:10.1073/pnas.121164898, pages 6742 - 6746, XP002329453
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EXAMINATION- LEE ET AL, "Whole cell biosynthesis of a functional oligosaccharide, 2'-fucosyllactose, using engineered Escherichia coli", MICROBIAL CELL FACTORIES, (2012), vol. 11, pages 1 - 9, XP021115889
OPPOSITION- Alignment of Pisum sativum FBPases- 2 September 2021-
OPPOSITION- Anonymous, "GRN No. 571 2'-Fucosyllactose", GRAS Notices, (20210827), page 1, XP055848082-
OPPOSITION- Anonymous, "Safety Evaluation of 2'-Fucosyllactose for use in term infant formulas and toddler formulas, Appendix K, Description and Safety Evaluation of E. coli BL21 ( DE 3) #1540", ENVIRON, (20141100), pages 282 - 301, XP055848079-
OPPOSITION- Drouillard S., Driguez H., Samain E., "Large-Scale Synthesis of H-AntigenOligosaccharides by Expressing Helicobacter pylori al,2-Fucosyltransferasein Metabolically Engineered Escherichia coli Cells", Angew. Chem. Int. Ed., (20060000), vol. 45, pages 1778 - 1780, XP055848101-
OPPOSITION- Jacquot Jean-Pierre, Javier Lopez-Jaramillo, Myroslawa Miginiac-Maslow,Stephane Lemaire, Jacqueline Cherfils, Ana Chueca, Julio Lopez-Gorge, "Cysteine-153 is required for redox regulation of pea chloroplast fructose-i,6-bisphosphatase", FEBS Letters, (19970000), vol. 401, pages 143 - 147, XP055848096-
OPPOSITION- LIN, E.C.C., "Dissimilatory Pathways for Sugars, Polyols, and Carboxylates", American Society for Microbiology, (19960000), pages 307 - 342, XP001246975-
OPPOSITION- Neidhardt Frederick C., "Escherichia coli and Salmonella typhimurium", American Society for Microbiology, (19960000), pages 189 - 191, XP055848085-
OPPOSITION- PETSCHACHER et al., "Biotechnological production of fucosylated human milk oligosaccharides: Prokaryotic fucosyltransferases and their use in biocatalytic cascades or whole cell conversion systems", Journal of Biotechnology, (20160401), vol. 235, doi:10.1016/j.jbiotec.2016.03.052, pages 61 - 83, XP029733274
OPPOSITION- Baumgärtner F., Seitz L., Sprenger G. A., Albermann C., "Construction of Escherichia coli strains with chromosomally integrated expression cassettes for the synthesis of 2'- fucosyllactose", Microbial Cell Factories, (20130501), vol. 12, no. 40, pages 1 - 13, XP021151035
OPPOSITION- GOTTLIEB et al., "Improvement of L-phenylalanine production from glycerol by recombinant Escherichia coli strains: The role of extra copies of glpK, glpX, and tktA genes", Microbial Cell Factories, (20140711), vol. 13, no. 96, pages 1 - 16, XP021195432
SEARCH- CHIN ET AL, "Metabolic engineering of Corynebacterium glutamicum to produce GDP-L-fucose from glucose and mannose", BIOPROCESS AND BIOSYSTEMS ENGINEERING, (2013), vol. 36, pages 749 - 756, XP002765469 [Y] 1-25 * See page 750 (Figure 1) *-
SEARCH- CHIN ET AL, "Metabolic engineering of Escherichia coli to produce 2'-fucosyllactose via salvage pathway of guanosine 5'-diphosphate (GDP)-L-fucose", BIOTECHNOLOGY AND BIOENGINEERING, (20160620), vol. 113, pages 2443 - 2452, XP002765455 [Y] 1-25 * See page 2445 (Figure 1); early online publication *-
SEARCH- ENGELS ET AL, "WbgL: a novel bacterial alpha-1,2-fucosyltransferase for the synthesis of 2'-fucosyllactose", GLYCOBIOLOGY, (2014), vol. 24, pages 170 - 178, XP002765456 [Y] 1-25 * See page 174 (Figure 3) *-
SEARCH- CHIN ET AL, "Enhanced production of 2'-fucosyllactose in engineered Escherichia coli BL21star(DE3) by modulation of lactose metabolism and fucosyltransferase", JOURNAL OF BIOTECHNOLOGY, (2015), vol. 210, pages 107 - 115, XP029261145 [Y] 1-25 * See page 110 (Figure 1) *
SEARCH- PETSCHACHER ET AL, "Biotechnological production of fucosylated human milk oligosaccharides: prokaryotic fucosyltransferases and their use in biocatalytic cascades or whole cell conversion systems", JOURNAL OF BIOTECHNOLOGY, (20160401), vol. 235, pages 61 - 83, XP029733274 [Y] 1-25 * See page 67 (Figure 2) as well as Tables 2-6; early online publication *
SEARCH- BAUMGÄRTNER ET AL, "Construction of Escherichia coli strains with chromosomally integrated expression cassettes for the synthesis of 2'-fucosyllactose", MICROBIAL CELL FACTORIES, (2013), vol. 12, pages 1 - 13, XP021151035 [A] 1-25 * See page 2 (Figure 1) *

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