IP Verse

Bispecific And Multispecific Antibodies And Method For Isolation Of Such - EP3319996

The patent EP3319996 was granted to Genmab on Jan 3, 2024. The application was originally filed on Jul 1, 2016 under application number EP16733969A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3319996

GENMAB
Application Number
EP16733969A
Filing Date
Jul 1, 2016
Status
Granted And Under Opposition
Dec 1, 2023
Grant Date
Jan 3, 2024
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions (2)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

MARGARET DIXONOct 3, 2024MEWBURN ELLISADMISSIBLE
SANOFIOct 3, 2024LAVOIXADMISSIBLE

Patent Citations (27) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONEP1870459
DESCRIPTIONUS5731168
DESCRIPTIONUS8586713
DESCRIPTIONWO02100348
DESCRIPTIONWO2004035607
DESCRIPTIONWO2007110205
DESCRIPTIONWO2008119353
DESCRIPTIONWO2009089004
DESCRIPTIONWO2011131746
DESCRIPTIONWO2011147986
DESCRIPTIONWO2012143524
DESCRIPTIONWO2013088259
DESCRIPTIONWO2013136186
EXAMINATIONWO2009080251
INTERNATIONAL-SEARCH-REPORTWO2008052933
INTERNATIONAL-SEARCH-REPORTWO2011131746
INTERNATIONAL-SEARCH-REPORTWO2013088259
INTERNATIONAL-SEARCH-REPORTWO2013136186
OPPOSITIONEP1870459
OPPOSITIONEP2522724
OPPOSITIONUS2010331527
OPPOSITIONUS2014066599
OPPOSITIONWO2008052933
OPPOSITIONWO2010151792
OPPOSITIONWO2013088259
OPPOSITIONWO2013136186
OPPOSITIONWO2014049003

Non-Patent Literature (NPL) Citations (11) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
OPPOSITION- D12-Experimental work: summary of products and sequences
OPPOSITION- D13-Experimental work: Declaration from WuXi Biologics
OPPOSITION- Nilson, B.H.K., Logdberg, L., Kastern, W., Bjorck, L. , Akerstrom, B., "Purification of antibodies using protein L-binding framework structures in the light chain variable domain", Journal of Immunological Methods, NL , (19930826), vol. 164, no. 1, doi:10.1016/0022-1759(93)90273-A, ISSN 0022-1759, pages 33 - 40, XP023974893
OPPOSITION- Muzard, J. ; Adi-Bessalem, S. ; Juste, M. ; Laraba-Djebari, F. ; Aubrey, N. ; Billiald, P., "Grafting of protein L-binding activity onto recombinant antibody fragments", Analytical Biochemistry, Amsterdam, NL , (20090515), vol. 388, no. 2, doi:10.1016/j.ab.2009.02.035, ISSN 0003-2697, pages 331 - 338, XP026052007
OPPOSITION- James, L.C. ,Jones, P.C., McCoy, A. ,Tennent, G.A.,Pepys, M.B., Famm, K., Winter, G., "β-Edge Interactions in a Pentadecameric Human Antibody Vk Domain", Journal of Molecular Biology, United Kingdom , (20070303), vol. 367, no. 3, doi:10.1016/j.jmb.2006.10.093, ISSN 0022-2836, pages 603 - 608, XP005910822
OPPOSITION- Graille Marc, Stura Enrico A, Housden Nicholas G, Beckingham Jennifer A, Bottomley Stephen P, Beale Dennis, Taussig Michael J, Sutton Brian J, Gore Michael G, Charbonnier Jean-Baptiste, "Complex betweenPeptostreptococcus magnusProteinL and a Human Antibody Reveals Structural Convergence in the Interaction Modes of Fab Binding Proteins", Structure, (20010801), vol. 9, no. 8, doi:/10.1016/S0969-2126(01)00630-X, pages 679 - 687, XP093231470
OPPOSITION- Theo Rispens, Pleuni Ooijevaar-De Heer, Onno Bende, Rob C. Aalberse, "Mechanism of Immunoglobulin G4 Fab-arm Exchange", Journal of the American Chemical Society, (20110706), vol. 133, no. 26, doi:10.1021/ja203638y, ISSN 0002-7863, pages 10302 - 10311, XP055201223
OPPOSITION- Nicolas Fischer, Greg Elson, Giovanni Magistrelli, Elie Dheilly, Nicolas Fouque, Amelie Laurendon, Franck Gueneau, Ulla Ravn, Jean-Francois Depoisier, Valery Moine, Sylvain Raimondi, Pauline Malinge, Laura Di Grazia, Francois Rousseau, Yves Poitevin, Sebastien Calloud, Pierre-Alexis Cayatte, Mathias Alcoz, Guillemette Pontini, Severine Fagete, Lucile Broyer, Marie Corbier, Delphine Schrag, Gerard Didelot, Nicolas Bosson, Nessie Costes, Laura Cons, Vanessa Buatois, Zoe Johnson, Walter Ferlin, Krzysztof Masternak, Marie Kosco-Vilbois, "Exploiting light chains for the scalable generation and platform purification of native human bispecific IgG", Nature Communications, (20151201), vol. 6, no. 1, doi:10.1038/ncomms7113, XP055514059
OPPOSITION- Aran F Labrijn, Joyce I Meesters, Patrick Priem, Rob N De Jong, Ewald T J Van Den Bremer, Muriel D Van Kampen, Arnout F Gerritsen, Janine Schuurman, Paul W H I Parren, "Controlled Fab-arm exchange for the generation of stable bispecific IgG1", Nature Protocols, (20140101), vol. 9, no. 10, doi:10.1038/nprot.2014.169, ISSN 1754-2189, pages 2450 - 2463, XP055201251
OPPOSITION- Housden N.G., Harrison S., Roberts S.E., Beckingham J.A., Graille M., Stura E., Gore M.G., "Immunoglobulin-binding domains: Protein L from Peptostreptococcus magnus", Biochemical Society Transactions, GB , (20030601), vol. 31, no. 3, doi:10.1042/bst0310716, ISSN 0300-5127, pages 716 - 718, XP093231493
OPPOSITION- Michael J Gramer, Ewald Tj Van Den Bremer, Muriel D Van Kampen, Amitava Kundu, Peter Kopfmann, Eric Etter, David Stinehelfer, Justin Long, Tom Lannom, Esther H Noordergraaf, Jolanda Gerritsen, Aran F Labrijn, Janine Schuurman, Patrick Hc Van Berkel, Paul Whi Parren, "Production of stable bispecific IgG1 by controlled Fab-arm exchange", mAbs, (20131101), vol. 5, no. 6, doi:10.4161/mabs.26233, ISSN 19420862, pages 962 - 973, XP055201119

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents