IP Verse

Method For Purifying Composition Comprising Antibodies With Anionic Polymer - EP3330279

The patent EP3330279 was granted to Chugai Seiyaku Kabushiki Kaisha on Apr 6, 2022. The application was originally filed on Jul 29, 2016 under application number EP16832930A. The patent is currently recorded with a legal status of "Opposition Rejected".

EP3330279

CHUGAI SEIYAKU KABUSHIKI KAISHA
Application Number
EP16832930A
Filing Date
Jul 29, 2016
Status
Opposition Rejected
Aug 22, 2025
Publication Date
Apr 6, 2022
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

NEUEFEINDJan 5, 2023MAIWALDADMISSIBLE

Patent Citations (4) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
INTERNATIONAL-SEARCH-REPORTWO2015099165
OPPOSITIONEP3330279
OPPOSITIONJP2015151981
SEARCHEP2644698

Non-Patent Literature (NPL) Citations (23) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
EXAMINATION- Anonymous, "9/08/2020 Proteins | Biology for Non-Majors I Proteins | Biology for Non-Majors I", (20200819), URL: https://courses.lumenlearning.com/wmopen-nmbiology1/chapter/proteins/#:%7E:text=Prote%E2%80%A6, (20200820), XP055723932
EXAMINATION- Anonymous, "Peptide - Wikipedia, the free encyclopedia", Wikipedia, the free encyclopedia, (20160712), pages 1 - 5, URL: https://en.wikipedia.org/w/index.php?title=Peptide&printable=yes, (20160714), XP055288608
EXAMINATION- Shigeru Kunugi, "Proteins as Polymers and Polyelectrolytes", Encyclopedia of Polymeric Nanomaterials, Berlin, Heidelberg, Springer Berlin Heidelberg, (20140101), pages 1 - 6, doi:10.1007/978-3-642-36199-9_167-1, ISBN 978-3-642-36199-9, XP055723935
EXAMINATION- DALKARA D ET AL, "Intracytoplasmic delivery of anionic proteins", MOLECULAR THERAPY, CELL PRESS, US, (20040601), vol. 9, no. 6, doi:10.1016/J.YMTHE.2004.03.007, ISSN 1525-0016, pages 964 - 969, XP002368719
INTERNATIONAL-SEARCH-REPORT- MCDONALD, P. et al., "Selective antibody precipitation using polyelectrolytes: a novel approach to the purification of monoclonal antibodies", Biotechnology and Bioengineering, vol. 102, no. 4, (20090301), pages 1141 - 1151, URL: http:// onlinelibrary. wiley .com/woll/doi/10.1002/bit. 22127/pdf, (20160912), XP003026475 [A] 1-21
INTERNATIONAL-SEARCH-REPORT- KANG, Y. K. et al., "Development of a novel and efficient cell culture flocculation process using a stimulus responsive polymer to streamline antibody purification processes", Biotechnology and Bioengineering, vol. 110, no. 11, (20130629), pages 2928 - 2937, URL: http://onlinelibrary. wiley .com/doi/10.1002/bit.24969/pdf, (20160912), XP055362755 [A] 1-21
INTERNATIONAL-SEARCH-REPORT- SIEBERZ, J. et al., "Identification of parameter interactions influencing the precipitation of a monoclonal antibody with anionic polyelectrolytes", Separation and Purification Technology, vol. 127, (20140430), pages 165 - 173, URL: http://www.sciencedirect.com/ science /article/ pii/S1383586614001348, XP028867946 [A] 1-21
INTERNATIONAL-SEARCH-REPORT- SIEBERZ, J. et al., "The influence of impurity proteins on the precipitation of a monoclonal antibody with anionic polyelectrolyte", Separation and Purification Technology, vol. 146, (20150526), pages 252 - 260, URL: http://www. sciencedirect.com/ science /article/pii/ S1383586615002178, XP029157013 [A] 1-21
OPPOSITION- Anonymous, " Emicizumab", DrugBank online, (20171116), DrugBank online, URL: https://go.drugbank.com/drugs/DB13923, (20230116), XP093014101
OPPOSITION- Ying Fan Wang, Jeff Y.Gao, Paul L.Dubin , "Protein separation vai polyelectrolyte coacervation selectivity and efficiency ", 356 Biotechnol. Prog, (19960101), vol. 12, pages 356 - 362, XP093014089
OPPOSITION- Ya Jin et al., "Estimation of isoelectric points of human plasma proteins employing capillary isoelectric focusing and peptide isoelectric point markers", Electrophoresis, (2002), vol. 23, doi:10.1002/1522-2683(200210)23:19<3385::AID-ELPS3385>3.0.CO;2-H, XP071496047
OPPOSITION- Paul McDonald; Corazon Victa; Jayme N. Carter‐Franklin; Robert Fahrner, "Selective antibody precipitation using polyelectrolytes: A novel approach to the purification of monoclonal antibodies", Biotechnology and Bioengineering, John Wiley, Hoboken, USA, Hoboken, USA, (20080919), vol. 102, no. 4, doi:10.1002/bit.22127, ISSN 0006-3592, pages 1141 - 1151, XP071052741
OPPOSITION- Matthew Westoby, James Chrostowski, Philippe De Vilmorin, John Paul Smelko, Jonathan K. Romero, "Effects of solution environment on mammalian cell fermentation broth properties: Enhanced impurity removal and clarification performance", Biotechnology and Bioengineering, Wiley ¬etc.|, (20110101), vol. 108, no. 1, doi:10.1002/bit.22923, ISSN 00063592, pages 50 - 58, XP055073850
OPPOSITION- Yun Kenneth Kang, Et Al, "Development of a novel and efficient cell culture flocculation process using a stimulus responsive polymer to streamline antibody purification processes", Biotechnology and Bioengineering, John Wiley, Hoboken, USA, Hoboken, USA, (20131101), vol. 110, no. 11, doi:10.1002/bit.24969, ISSN 0006-3592, pages 2928 - 2937, XP055362755
OPPOSITION- Daisuke Ejima, Ryosuke Yumioka, Kouhei Tsumoto, Tsutomu Arakawa, "Effective elution of antibodies by arginine and arginine derivatives in affinity column chromatography", Analytical Biochemistry, Academic Press, Amsterdam, NL , (20051001), vol. 345, no. 2, doi:10.1016/j.ab.2005.07.004, ISSN 0003-2697, pages 250 - 257, XP055545396
OPPOSITION- Arakawa, T. Philo, J.S. Tsumoto, K. Yumioka, R. Ejima, D., "Elution of antibodies from a Protein-A column by aqueous arginine solutions", Protein Expression and Purification, ACADEMIC PRESS, SAN DIEGO, CA. , (20040801), vol. 36, no. 2, doi:10.1016/j.pep.2004.04.009, ISSN 1046-5928, pages 244 - 248, XP004520288
OPPOSITION- Sieberz Julia; Wohlgemuth Kerstin; Schembecker Gerhard, "The influence of impurity proteins on the precipitation of a monoclonal antibody with an anionic polyelectrolyte", SEPARATION AND PURIFICATION TECHNOLOGY, ELSEVIER SCIENCE, AMSTERDAM, NL, NL , (19000101), vol. 146, doi:10.1016/j.seppur.2015.03.055, ISSN 1383-5866, pages 252 - 260, XP029157013
SEARCH- CAPITO FLORIAN ET AL, "Host cell protein quantification by Fourier transform mid infrared spectroscopy (FT-MIR).", BIOTECHNOLOGY AND BIOENGINEERING JAN 2013, (201301), vol. 110, no. 1, ISSN 1097-0290, pages 252 - 259, XP002786519 [X] 1-5,7-10 * page 253, column right *
SEARCH- CAPITO FLORIAN ET AL, "Matrix effects during monitoring of antibody and host cell proteins using attenuated total reflection spectroscopy.", BIOTECHNOLOGY PROGRESS, (201301), vol. 29, no. 1, ISSN 1520-6033, pages 265 - 274, XP002786518 [X] 1-5,7-10 * page 266, column right * * page 267, column left *
SEARCH- FLORIAN CAPITO ET AL, "Feasibility of polyelectrolyte-driven Fab fragment separation", BIOTECHNOLOGY JOURNAL, (20140504), vol. 9, no. 5, doi:10.1002/biot.201400029, ISSN 1860-6768, pages 698 - 701, XP055184414 [A] 1-15 * paragraphs [02.1] , [ 2.2] * * page 700, column left, lines 17-20 * * abstract *
SEARCH- MCDONALD P ET AL, "Selective antibody precipitation using polyelectrolytes: a novel approach to the purifiation of monoclonal antibodies", BIOTECHNOLOGY AND BIOENGINEERING, WILEY, US, vol. 102, no. 4, doi:10.1002/BIT.22127, ISSN 0006-3592, (20090301), pages 1141 - 1151, (20080919), XP003026475 [X] 1-13 * tables II, III, IV * * page 1142, column left * * figure 3 * * page 1145, column left * * page 1147, column right * * page 1148 * [I] 14
SEARCH- FULTON ANDREW ET AL, "Purification of monoclonal antibody against Ebola GP1 protein expressed inNicotiana benthamiana", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER, AMSTERDAM, NL, (20150211), vol. 1389, doi:10.1016/J.CHROMA.2015.02.013, ISSN 0021-9673, pages 128 - 132, XP029204491 [A] 1-15 * paragraphs [02.4] , [ 3.2] , [ 2.2] *
SEARCH[ ] - FAHRNER R L ET AL, "Industrial Purification of Pharmaceutical Antibodies: Development, Operation, and Validation of Chromatography Processes", BIOTECHNOLOGY AND GENETIC ENGINEERING REVIEWS, INTERCEPT LTD., ANDOVER, GB, (20010701), vol. 18, no. 12, doi:10.1080/02648725.2001.10648017, ISSN 0264-8725, pages I - II, XP003035628 [ ] * table 12.1 *

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents