| OPPOSITION | - 29th, General, Assembly, Tokyo, Japan, "WORLD MEDICAL ASSOCIATION DECLARATION OF HELSINKI Ethical Principles for Medical Research Involving Human Subjects", 53rd WMA General AssemblyNote of Clarification on Paragraph 30 added) 59th WMA General Assembly, 53rd WMA General AssemblyNote of Clarification on Paragraph 30 added) 59th WMA General Assembly, URL: https://icgc.org/files/daco/WMA_Helsinki_2008_en.pdf, (20200420), XP055687498 | - |
| OPPOSITION | - "3.2 Corticosteroids", British National Formulary, London, RPS Publishing, (20090801), vol. 58, pages 165 - 169, ISBN 978-0-85369-848-7, XP009559982 | - |
| OPPOSITION | - Anonymous, "ANORO 55 micrograms/22 micrograms inhalation powder, pre-dispensed ; SUMMARY OF PRODUCT CHARACTERISTICS (SmPC)", SUMMARY OF PRODUCT CHARACTERISTICS, European Medicines Agency, pages 1 - 39, SUMMARY OF PRODUCT CHARACTERISTICS , URL: https://ec.europa.eu/health/documents/community-register/2016/20160922135721/anx_135721_en.pdf, XP093256665 | - |
| OPPOSITION | - Anonymous, "A Study To Assess Efficacy And Safety Of Different Doses Of GW642444 In Subjects With Chronic Obstructive Pulmonary Disease (COPD)", ClinicalTrials.gov Identifier: NCT00606684, ClinicalTrials.gov Identifier: NCT00606684, URL: clinicaltrials.gov, (20200514), XP055695558 | - |
| OPPOSITION | - Anonymous, "EU Approval of EKLIRA GENUAIR - Annex I, Summary of product characteristics", European Medicines Agency, European Medicines Agency, URL: https://ec.europa.eu/health/documents/community-register/2012/20120720123594/anx_123594_en.pdf, XP002780227 | - |
| OPPOSITION | - Anonymous, "GSK filing accepted by European Medicines Agency for Trelegy Ellipta use in adult patients with asthma", GSK News release, GSK, pages 1 - 8, GSK News release, URL: https://www.gsk.com/en-gb/media/press-releases/gsk-filing-accepted-by-european-medicines-agency-for-trelegy-ellipta-use-in-adult-patients-with-asthma/, XP093257483 | - |
| OPPOSITION | - Anonymous, "GSK & Theravance announce positive phase-2b results of COPD trial", PharmaBiz News, PharmaBiz, pages 1 - 1, PharmaBiz News, URL: http://test.pharmabiz.com/news/gsk-theravance-announce-positive-phase-2b-results-of-copd-trial-48251, XP093257552 | - |
| OPPOSITION | - Anonymous, "HIGHLIGHTS OF PRESCRIBING INFORMATION", Forrest Pharmaceuticals, Inc., St. Louis, St. Louis , pages 1 - 23, URL: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202450s000lbl.pdf, (20141114), XP055153070 | - |
| OPPOSITION | - Anonymous, "History of Changes for Study: NCT00976144 - Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effects of GSK573719 (LAMA) and GW642444 (LABA)Administered Individually and Concurrently in Healthy Japanese Subjects (DB2113208)", clinicaltrials.gov, pages 1 - 5, clinicaltrials.gov, URL: https://clinicaltrials.gov/ct2/history/NCT00976144?A=1&B=1&C=merged#StudyPageTop, (20220715), XP055943101 | - |
| OPPOSITION | - Anonymous, "International Nonproprietary Names for Pharmaceutical Substances (INN): Proposed INN: List 99", WHO DRUG INFORMATION, GENEVA, CH, CH , (20080609), vol. 22, no. 2, ISSN 1010-9609, pages 121 - 174, XP093257385 | - |
| OPPOSITION | - Anonymous, "Label: Spiriva® HandiHaler® (tiotropium bromide inhalation powder)", Label, FDA, pages 1 - 29, Label, URL: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021395s014lbl.pdf, XP093257501 | - |
| OPPOSITION | - Anonymous, "NCT00732472 | A Study to Assess the Safety and Tolerability of Once Daily Inhaled Doses of GSK573719 Made With Magnesium Stearate in Subjects With Chronic Obstructive Pulmonary Disease(COPD)for 7 Days", ClinicalTrials.gov, NLM, pages 1 - 15, ClinicalTrials.gov, URL: https://clinicaltrials.gov/study/NCT00732472?cond=NCT00732472%20&rank=1&tab=history&a=6#version-content-panel, XP093257466 | - |
| OPPOSITION | - Anonymous, "New Drug Application (NDA): 203975", Drugs@FDA: FDA-Approved Drugs, US Food & Drug Administration (FDA), pages 1 - 2, Drugs@FDA: FDA-Approved Drugs, URL: https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=BasicSearch.process, XP093257377 | - |
| OPPOSITION | - Anonymous, "Safety, tolerability, pharmacokinetic and pharmacodynamic effects of GSK573719 (LAMA) and GW642444 (LABA)administered individually and concurrently in healthy Japanese subjects (GSK Study ID: 113208), (ClinicalTrials.gov Identifier: NCT00976144)", GSK Study Register, GlaxoSmithKline plc., pages 1 - 517, GSK Study Register, URL: https://www.gsk-studyregister.com/en/trial-details/?id=113208, XP093257447 | - |
| OPPOSITION | - Anonymous , "Umeclidinium bromide | C29H34BrNO2", PubChem COMPOUND, XP055943090 | - |
| OPPOSITION | - Anonymous, "USP 31 / NF 26", US Pharmacopeia, (20080501), vol. 1, pages 605 - 607, XP055697910 | - |
| OPPOSITION | - Anonymous , "Vilanterol | C24H33Cl2NO5", Pubchem COMPOUND, XP055943094 | - |
| OPPOSITION | - Calisha Myers, "GSK and Teravance announce positive phase 2b results for LABA, '444 in the Horizon Asthma Development Programme", FierceBiotech, FierceBiotech, URL: https://www.fiercebiotech.com/biotech/gsk-and-theravance-announce-positive-phase-2b-results-for-laba-444-horizon-asthma, (20200513), XP055694882 | - |
| OPPOSITION | - Cazzola, M., "Aclidinium bromide, a novel long-acting muscarinic M3 antagonist for the treatment of COPD", CURRENT OPINION IN INVESTIGATIONAL DRUGS, PHARMAPRESS, US, US , (20090101), vol. 10, no. 5, ISSN 1472-4472, pages 482 - 490, XP009559977 | - |
| OPPOSITION | - D13 - T0484/09 | - |
| OPPOSITION | - D31a - USAN for Umeclidinium | - |
| OPPOSITION | - D31b - USAN for Umeclidinium bromide | - |
| OPPOSITION | - D31c - USAN for Vilanterol | - |
| OPPOSITION | - D31d - USAN for Vilanterol trifenatate | - |
| OPPOSITION | - D47 - Consent form concerning clinical study NCT00976144 | - |
| OPPOSITION | - D51 - Consent form concerning clinical study NCT00606684 | - |
| OPPOSITION | - D53 - Consent form concerning clinical study NCT00732472 | - |
| OPPOSITION | - D57 - T0237/15 | - |
| OPPOSITION | - D59 - T0239/16 | - |
| OPPOSITION | - D61 - Decision of the Opposition Division dated April 13, 2016 in respect of EP 1 931 350 | - |
| OPPOSITION | - D62 - T0184/16 | - |
| OPPOSITION | - D63 - T2015/20 | - |
| OPPOSITION | - D64 - Case law discussion | - |
| OPPOSITION | - D65 - T0106/07 | - |
| OPPOSITION | - D66 - T0334/92 | - |
| OPPOSITION | - D67 - T0296/93 | - |
| OPPOSITION | - D68 - T0293/07 | - |
| OPPOSITION | - D69 - T0847/07 | - |
| OPPOSITION | - D70 - T0488/16 | - |
| OPPOSITION | - d75 - T0383/10 | - |
| OPPOSITION | - Gina Teams, "The global strategy for asthma management and prevention", Global Initiative for Asthma, Global Initiative for Asthma, (20181031), XP055520525 | - |
| OPPOSITION | - Gold Teams, "The global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease", Executive Summary. Global Initiative for Chronic Obstructive Lung Disease, Executive Summary. Global Initiative for Chronic Obstructive Lung Disease, (20181031), XP055520517 | - |
| OPPOSITION | - P. J. Barnes, Et Al, "The Pharmacological Properties of Tiotropium", Chest, (20000201), vol. 117, no. 2, pages 63S - 65S, XP055520530 | - |
| OPPOSITION | - X M Zeng, Et Al, "5.5.3 Drug-carrier Formulations", X M Zeng, Et Al, Xian Ming Zeng; Gary P. Martin; Christopher Marriot, Particulate interactions in dry powder formulations for inhalation -Passage , Taylor & Francis, (20010101), pages 155 - 159, ISBN 0-7484-0960-2, XP055697867 | - |
| OPPOSITION | - Jones, Paul, "Aclidinium Bromide Twice Daily for the Treatment of Chronic Obstructive Pulmonary Disease: A Review", ADVANCES IN THERAPY., HEALTH COMMUNICATIONS, METUCHEN, NJ., US, US , (20130401), vol. 30, no. 4, doi:10.1007/s12325-013-0019-2, ISSN 0741-238X, pages 354 - 368, XP009504915 | |
| OPPOSITION | - VandeVrede Lawren; Ljubenkov Peter A.; Rojas Julio C.; Welch Ariane E.; Boxer Adam L., "Four-Repeat Tauopathies: Current Management and Future Treatments", Neurotherapeutics, Springer International Publishing, Cham, Cham, (19000101), vol. 17, no. 4, doi:10.1007/s13311-020-00888-5, ISSN 1933-7213, pages 1563 - 1581, XP037354100 | |
| OPPOSITION | - Alcázar Navarrete Bernardino, Boucot Isabelle, Naya Ian, Tombs Lee, Lipson David A., Compton Chris, Sousa Ana R., Feldman Gregory, "Umeclidinium/Vilanterol Versus Tiotropium/Olodaterol in Maintenance-Naïve Patients with Moderate Symptomatic Chronic Obstructive Pulmonary Disease: A Post Hoc Analysis", Pulmonary Therapy, (20181201), vol. 4, no. 2, doi:10.1007/s41030-018-0057-7, ISSN 2364-1754, pages 171 - 183, XP093257492 | |
| OPPOSITION | - Waldeck Bertil, "Some pharmacodynamic aspects on long-acting β-adrenoceptor agonists", GENERAL PHARMACOLOGY., PERGAMON PRESS, OXFORD., GB, GB , (19960601), vol. 27, no. 4, doi:10.1016/0306-3623(95)02052-7, ISSN 0306-3623, pages 575 - 580, XP093257486 | |
| OPPOSITION | - Barnes, P.J., "The role of anticholinergics in chronic obstructive pulmonary disease", AMERICAN JOURNAL OF MEDICINE SUPPLEMENTS, ELSEVIER, AMSTERDAM, NL, NL , (20041220), vol. 117, no. 12, doi:10.1016/j.amjmed.2004.10.018, ISSN 1548-2766, pages 24 - 32, XP004687940 | |
| OPPOSITION | - Cazzola, M. Matera, M.G., "The effective treatment of COPD: Anticholinergics and what else?", Drug Discovery Today: Therapeutic Strategies, Elsevier, AMSTERDAM, NL, AMSTERDAM, NL , (20061123), vol. 3, no. 3, doi:10.1016/j.ddstr.2006.09.009, ISSN 1740-6773, pages 277 - 286, XP005777432 | |
| OPPOSITION | - Gross, N.J., "Anticholinergic agents in asthma and COPD", European Journal of Pharmacology, Elsevier science, NL, NL , (20060308), vol. 533, no. 1-3, doi:10.1016/j.ejphar.2005.12.072, ISSN 0014-2999, pages 36 - 39, XP028028951 | |
| OPPOSITION | - Tal-Singer Ruth; Cahn Anthony; Mehta Rashmi; Preece Andrew; Crater Glenn; Kelleher Dennis; Pouliquen Isabelle J., "Initial assessment of single and repeat doses of inhaled umeclidinium in patients with chronic obstructive pulmonary disease: Two randomised studies", European Journal of Pharmacology, Elsevier science, NL, NL , (20121228), vol. 701, no. 1, doi:10.1016/j.ejphar.2012.12.019, ISSN 0014-2999, pages 40 - 48, XP028994453 | |
| OPPOSITION | - Kuna, P. ; Creemers, J.P.H.M. ; Vondra, V. ; Black, P.N. ; Lindqvist, A. ; Nihlen, U. ; Vogelmeier, C., "Once-daily dosing with budesonide/formoterol compared with twice-daily budesonide/formoterol and once-daily budesonide in adults with mild to moderate asthma", Respiratory Medicine, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (20061201), vol. 100, no. 12, doi:10.1016/j.rmed.2006.03.016, ISSN 0954-6111, pages 2151 - 2159, XP026055074 | |
| OPPOSITION | - James F. Donohue; Antonio Anzueto; Jean Brooks; Rashmi Mehta; Christopher Kalberg; Glenn Crater;, "A randomized, double-blind dose-ranging study of the novel LAMA GSK573719 in patients with COPD", Respiratory Medicine, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (20120316), vol. 106, no. 7, doi:10.1016/j.rmed.2012.03.012, ISSN 0954-6111, pages 970 - 979, XP028423483 | |
| OPPOSITION | - Donohue J.F.; Maleki-Yazdi M.R.; Kilbride S.; Mehta R.; Kalberg C.; Church A., "Efficacy and safety of once-daily umeclidinium/vilanterol 62.5/25 mcg in COPD ", Respiratory Medicine, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (19000101), vol. 107, no. 10, doi:10.1016/j.rmed.2013.06.001, ISSN 0954-6111, pages 1538 - 1546, XP028720235 | |
| OPPOSITION | - Maleki-Yazdi M. Reza, Kaelin Thomas, Richard Nathalie, Zvarich Michael, Church Alison, "Efficacy and safety of umeclidinium/vilanterol 62.5/25 mcg and tiotropium 18 mcg in chronic obstructive pulmonary disease: Results of a 24-week, randomized, controlled trial", Respiratory Medicine, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (20141201), vol. 108, no. 12, doi:10.1016/j.rmed.2014.10.002, ISSN 0954-6111, pages 1752 - 1760, XP093257490 | |
| OPPOSITION | - Donohue James F.; Singh Dave; Munzu Clara; Kilbride Sally; Church Alison, "Magnitude of umeclidinium/vilanterol lung function effect depends on monotherapy responses: Results from two randomised controlled trials", Respiratory Medicine, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (20160107), vol. 112, doi:10.1016/j.rmed.2016.01.001, ISSN 0954-6111, pages 65 - 74, XP029434171 | |
| OPPOSITION | - Dramane I. Laineì, Brent McCleland, Sonia Thomas, Christopher Neipp, Brian Underwood, Jeremy Dufour, Katherine L. Widdowson, Michael R. Palovich, Frank E. Blaney, James J. Foley, Edward F. Webb, Mark A. Luttmann, Miriam Burman, Kristen Belmonte, and Michael Salmon, "Discovery of Novel 1-Azoniabicyclo[2.2.2]octane Muscarinic Acetylcholine Receptor Antagonists", Journal of Medicinal Chemistry, American Chemical Society, US, US , (20090423), vol. 58, no. 8, doi:10.1021/jm801601v, ISSN 0022-2623, pages 2493 - 2505, XP002691510 | |
| OPPOSITION | - María Prat, Dolors Fernández, M. Antonia Buil, María I. Crespo, Gaspar Casals, Manuel Ferrer, Laia Tort, Jordi Castro, Juan M. Monleón, Amadeu Gavaldà, Montserrat Miralpeix, Israel Ramos, Teresa Doménech, Dolors Vilella, Francisca Antón, Josep M. Huerta, Sonia Espinosa, Manuel López, Sonia Sentellas, Marisa González, Joan Albertí, Victor Segarra, Alvaro Cárdenas, Jorge Beleta, Hamish Ryder, "Discovery of Novel Quaternary Ammonium Derivatives of (3 R )-Quinuclidinol Esters as Potent and Long-Acting Muscarinic Antagonists with Potential for Minimal Systemic Exposure after Inhaled Administration: Identification of (3 R )-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane Bromide (Aclidinium Bromide)", Journal of Medicinal Chemistry, American Chemical Society, (20090827), vol. 52, no. 16, doi:10.1021/jm900132z, ISSN 00222623, pages 5076 - 5092, XP055024812 | |
| OPPOSITION | - Lainé Dramane I., Wan Zehong, Yan Hongxing, Zhu Chongjie, Xie Haibo, Fu Wei, Busch-Petersen Jakob, Neipp Christopher, Davis Roderick, Widdowson Katherine L., Blaney Frank E., Foley James, Bacon Alicia M., Webb Edward F., Luttmann Mark A., Burman Miriam, Sarau Henry M., Salmon Michael, Palovich Michael R., Belmonte Kristen, "Design, Synthesis, and Structure−Activity Relationship of Tropane Muscarinic Acetylcholine Receptor Antagonists", Journal of Medicinal Chemistry, American Chemical Society, US, US , (20090827), vol. 52, no. 16, doi:10.1021/jm900736e, ISSN 0022-2623, pages 5241 - 5252, XP093257386 | |
| OPPOSITION | - M Cazzola; M G Matera, "Novel long‐acting bronchodilators for COPD and asthma", British journal of pharmacology, Wiley-Blackwell, UK, UK , (20090129), vol. 155, no. 3, doi:10.1038/bjp.2008.284, ISSN 0007-1188, pages 291 - 299, XP071170436 | |
| OPPOSITION | - Lotvall, J., "Pharmacological similarities and differences between beta2-agonists", Respiratory Medicine, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (20010801), vol. 95, no. Suppl. B, doi:10.1053/rmed.2001.1139, ISSN 0954-6111, pages S7 - S11, XP005569105 | |
| OPPOSITION | - Schelfhout Vanessa J; Ferrer Pau; Jansat Josep Maria; Peris Francesc; Gil Esther Garcia; Pauwels Romain A; Joos Guy F, "Activity of aclidinium bromide, a new long-acting muscarinic antagonist: a phase I study", British journal of clinical pharmacology, BLACKWELL SCIENTIFIC PUBL., GB, GB , (20100430), vol. 69, no. 5, doi:10.1111/j.1365-2125.2010.03622.x, ISSN 0306-5251, pages 458 - 464, XP009504914 | |
| OPPOSITION | - Perng D -W; Wu C -C; Su K -C; Lee Y -C; Perng R -P; Tao C -W, "Additive benefits of tiotropium in COPD patients treated with long-acting [beta]2 agonists and corticosteroids", Respirology, Blackwell Pub., Hoboken, USA, Hoboken, USA, (20060101), vol. 11, no. 5, doi:10.1111/j.1440-1843.2006.00889.x, ISSN 1323-7799, pages 598 - 602, XP009147876 | |
| OPPOSITION | - Ball D.I., Brittain R.T., Coleman R.A., Denyer L.H., Jack D., Johnson M., Lunts L.H.C., Nials A.T., Sheldrick K.E., Skidmore I.F., "Salmeterol, a novel, long‐acting β 2 ‐adrenoceptor agonist: characterization of pharmacological activity in vitro and in vivo", British journal of pharmacology, Wiley-Blackwell, UK, UK , (19911101), vol. 104, no. 3, doi:10.1111/j.1476-5381.1991.tb12486.x, ISSN 0007-1188, pages 665 - 671, XP093257496 | |
| OPPOSITION | - Nials A.T., Coleman R.A., Johnson M., Magnussen H., Rabe K.F., Vardey C.J., "Effects of β‐adrenoceptor agonists in human bronchial smooth muscle", British journal of pharmacology, Wiley-Blackwell, UK, UK , (19931101), vol. 110, no. 3, doi:10.1111/j.1476-5381.1993.tb13929.x, ISSN 0007-1188, pages 1112 - 1116, XP093257494 | |
| OPPOSITION | - Eric Bateman, Gregory Feldman, Sally Kilbride, Jean Brooks, Rashmi Mehta, Stephanie Harris, Claire Maden, Glenn Crater, "Efficacy and safety of the long-acting muscarinic antagonist GSK233705 delivered once daily in patients with COPD : Efficacy and safety of GSK233705 in COPD", The Clinical Respiratory Journal, John Wiley & Sons, Inc., Hoboken, USA, Hoboken, USA, (20121001), vol. 6, no. 4, doi:10.1111/j.1752-699X.2011.00278.x, ISSN 1752-6981, pages 248 - 257, XP055588856 | |
| OPPOSITION | - BATTRAM C ET AL., "IN VITRO AND IN VIVO PHARMACOLOGICAL CHARACTERIZATION OF 5-((R)-2-(5,6-DIETHYL-INDAN-2-YLAMINO)-1-HYDROXY-ETHYL)-8-HYDROXY-1H-QUINOLIN-2-ONE (INDACATEROL), A NOVEL INHALED BETA2 ADRENORECEPTOR AGONIST WITH A 24-H DURATION OF ACTION", The journal of pharmacology and experimental therapeutics, Elsevier Inc, United States, United States, (20060101), vol. 317, no. 2, doi:10.1124/jpet.105.098251, ISSN 0022-3565, pages 762 - 770, XP009077149 | |
| OPPOSITION | - Casarosa Paola, Bouyssou Thierry, Germeyer Sabine, Schnapp Andreas, Gantner Florian, Pieper Michael, "Preclinical Evaluation of Long-Acting Muscarinic Antagonists: Comparison of Tiotropium and Investigational Drugs", Pharmacological Reviews, American Society for Pharmacology and Experimental Therapeutics, US, US , (20090801), vol. 330, no. 2, doi:10.1124/jpet.109.152470, ISSN 0031-6997, pages 660 - 668, XP009559976 | |
| OPPOSITION | - Villetti, Pastore, Bergamaschi, Bassani, Bolzoni, Battipaglia, Amari, Rizzi, Delcanale, Volta, Cenacchi, Cacciani, Zaniboni, Berti, Rossoni, Harrison, Petrillo, Santoro, Scudellaro, Mannini, Geppetti, Razzetti, Patacchini, Civelli, "Bronchodilator Activity of (3R)-3-[[[(3-fluorophenyl)[(3,4,5-trifluorophenyl)methyl]amino] carbonyl]oxy]-1-[2-oxo-2-(2-thienyl)ethyl]-1-azoniabicyclo[2.2.2]octane bromide (CHF5407), a Potent, Long-Acting, and Selective Muscarinic M3 Receptor Antagonist", Journal of Pharmacology and Experimental Therapeutics, PHARMACOLOGICAL REVIEWS, United States, United States, (20101201), vol. 335, no. 3, doi:10.1124/jpet.110.170035, ISSN 1521-0081, pages 622 - 635, XP009559980 | |
| OPPOSITION | - M. Cazzola, C. P. Page, L. Calzetta, M. G. Matera, "Pharmacology and Therapeutics of Bronchodilators", Pharmacological Reviews, American Society for Pharmacology and Experimental Therapeutics, US, US , (20120701), vol. 64, no. 3, doi:10.1124/pr.111.004580, ISSN 0031-6997, pages 450 - 504, XP055083801 | |
| OPPOSITION | - Rodger Kempsford, Virginia Norris, Sarah Siederer, "GW642444, a Novel Inhaled Long-acting Beta2 Adrenoceptor Agonist (LABA) at single doses of 25, 50 and 100 mcg, is well tolerated an demonstrates prolonged bronchodilation in COPD Patients", American Journal of Respiratory and Critical Care Medicine, (20100101), vol. 181, no. Suppl., doi:10.1164/ajrccm-conference.2010.181.1_MeetingAbstracts.A4447 , ISSN 1073-449X, pages A4447 - A4447, XP009559974 | |
| OPPOSITION | - Rabe Klaus F., Hurd Suzanne, Anzueto Antonio, Barnes Peter J., Buist Sonia A., Calverley Peter, Fukuchi Yoshinosuke, Jenkins Christine, Rodriguez-Roisin Roberto, Van Weel Chris, Zielinski Jan, "Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease : GOLD Executive Summary", American Journal of Respiratory and Critical Care Medicine, (20070915), vol. 176, no. 6, doi:10.1164/rccm.200703-456SO, ISSN 1073-449X, pages 532 - 555, XP093257542 | |
| OPPOSITION | - M. Cazzola, M. G. Matera, "Emerging inhaled bronchodilators: an update", European Respiratory Journal, European Respiratory Society, (20090901), vol. 34, no. 3, doi:10.1183/09031936.00013109, ISSN 0903-1936, pages 757 - 769, XP055697899 | |
| OPPOSITION | - Cazzola M, Macnee W, Martinez F. J, Rabe K. F, Franciosi L. G, Barnes P. J, Brusasco V, Burge P. S, Calverley P., Celli B. R, Jones P. W, Mahler D. A, Make B, Miravitlles M, Page C. P, Palange P, Parr D, Pistolesi M, Rennard S. I, Rutten-Van Molken M. P, Stockley R, Sullivan S. D, Wedzicha J. A, Wouters E. F, On Behalf Of American Thoracic Society/european Respiratory Society Task Force On Outcomes Of Copd, "Outcomes for COPD pharmacological trials: from lung function to biomarkers", European Respiratory Journal, European Respiratory Society, Leeds, Leeds, (20080201), vol. 31, no. 2, doi:10.1183/09031936.00099306, ISSN 0903-1936, pages 416 - 469, XP009559984 | |
| OPPOSITION | - Van-Noord, Aumann J-L., Janssens, Smeets, Verhaert, Disse, Mueller, Cornelissen P. J. G., "Comparison of tiotropium once daily, formoterol twice daily and both combined once daily in patients with COPD", European Respiratory Journal, European Respiratory Society, Leeds, Leeds, (20050801), vol. 26, no. 2, doi:10.1183/09031936.05.00140404, ISSN 0903-1936, pages 214 - 222, XP009559990 | |
| OPPOSITION | - Cazzola M, "Current opinion: Pharmacological approaches in asthma and COPD", Breathe, (20090901), vol. 6, no. 1, doi:10.1183/18106838.0601.024, ISSN 1810-6838, pages 24 - 35, XP055943110 | |
| OPPOSITION | - Gupta Abhay, Hamad Mazen L., Tawakkul Mobin, Sayeed Vilayat A., Khan Mansoor A., "Difference in the Lubrication Efficiency of Bovine and Vegetable-Derived Magnesium Stearate During Tabletting", AAPS PharmSciTech, (20090602), vol. 10, no. 2, doi:10.1208/s12249-009-9229-y, pages 500 - 504, XP055943118 | |
| OPPOSITION | - Nicola A. Hanania, Et Al, "The Efficacy and Safety of the Novel Long-Acting beta2 Agonist Vilanterol in Patients With COPD - A Randomized Placebo-Controlled Trial", CHEST, (20120701), vol. 142, no. 1, doi:10.1378/chest.11-2231, pages 119 - 127, XP055214172 | |
| OPPOSITION | - CAZZOLA M, ET AL, "Ultra long-acting beta2-agonists in development for asthma and chronic obstructive pulmonary disease", Expert Opinion on Investigational Drugs, Informa Healthcare, UK, UK , (20050701), vol. 14, no. 7, doi:10.1517/13543784.14.7.775, ISSN 1354-3784, pages 775 - 783, XP003026042 | |
| OPPOSITION | - Aaron Shawn, Vandemheen Katherine, Fergusson Dean, Maltais Franã§ois, Bourbeau Jean, Goldstein Roger, Balter Meyer, O'donnell Denis, Mcivor Andrew, Sharma Sat, Bishop Graham, Anthony John, Cowie Robert, Field Stephen, Hirsch Andrew, Hernandez Paul, Rivington Robert, Road Jeremy, Hoffstein Victor, Hodder Richard, Marciniuk Darcy, Mccormack David, Fox George, Cox Gerard, Prins Henry, Ford Gordon, Bleskie Dominique, Doucette Steve, Mayers Irvin, Chapman Kenneth, Zamel Noe, Fitzgerald Mark, "Tiotropium in Combination with Placebo, Salmeterol, or Fluticasone-Salmeterol for Treatment of Chronic Obstructive Pulmonary Disease", Annals of Internal Medicine, [American College of Physicians], United States, United States, (20070417), vol. 146, no. 8, doi:10.7326/0003-4819-146-8-200704170-00152, ISSN 0003-4819, pages 545 - 555, XP009559986 | |
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