IP Verse

Polynucleotides Containing A Stabilizing Tail Region - EP3350333

The patent EP3350333 was granted to Moderna on Aug 6, 2025. The application was originally filed on Sep 19, 2016 under application number EP16847531A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP3350333

MODERNA
Application Number
EP16847531A
Filing Date
Sep 19, 2016
Status
Patent Maintained As Amended
Jul 4, 2025
Grant Date
Aug 6, 2025
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

STRAWMANJul 26, 2022BRAND MURRAY FULLERADMISSIBLE

Patent Citations (50) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS2005222064
DESCRIPTIONUS4270537
DESCRIPTIONUS4596556
DESCRIPTIONUS4790824
DESCRIPTIONUS4886499
DESCRIPTIONUS4940460
DESCRIPTIONUS4941880
DESCRIPTIONUS5015235
DESCRIPTIONUS5064413
DESCRIPTIONUS5141496
DESCRIPTIONUS5190521
DESCRIPTIONUS5208020
DESCRIPTIONUS5312335
DESCRIPTIONUS5328483
DESCRIPTIONUS5334144
DESCRIPTIONUS5339163
DESCRIPTIONUS5383851
DESCRIPTIONUS5417662
DESCRIPTIONUS5466220
DESCRIPTIONUS5475092
DESCRIPTIONUS5480381
DESCRIPTIONUS5503627
DESCRIPTIONUS5520639
DESCRIPTIONUS5527288
DESCRIPTIONUS5569189
DESCRIPTIONUS5585499
DESCRIPTIONUS5599302
DESCRIPTIONUS5649912
DESCRIPTIONUS5704911
DESCRIPTIONUS5846545
DESCRIPTIONUS5893397
DESCRIPTIONUS5993412
DESCRIPTIONWO9713537
DESCRIPTIONWO9737705
DESCRIPTIONWO9934850
INTERNATIONAL-SEARCH-REPORTUS2003170876
INTERNATIONAL-SEARCH-REPORTUS2013259923
INTERNATIONAL-SEARCH-REPORTUS2015167017
OPPOSITIONUS2005074760
OPPOSITIONUS2009075342
OPPOSITIONUS2009156528
OPPOSITIONUS2013035368
OPPOSITIONUS2014147454
OPPOSITIONWO2016011222
OPPOSITIONWO2016011226
SEARCHDE102006051516
SEARCHWO2013036748
SEARCHWO2013103659
SEARCHWO2015101414
SEARCHWO9914346

Non-Patent Literature (NPL) Citations (60) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- A. DAGH. DURMAZU. TUNCAG. HIZAL, J. Polym. Sci. Part A, (20090000), vol. 47, pages 178 - 187-
DESCRIPTION- A. F. JACOBINE, Radiation Curing in Polymer Science and Technology III, Elsevier, (19930000), pages 219 - 268-
DESCRIPTION- A. J. INGLISS. SINWELLM. H. STENZELC. BARNER-KOWOLLIK, Angew. Chem., (20090000), vol. 121, pages 2447 - 2450-
DESCRIPTION- Angew. Chem. Int. Ed., (20020000), vol. 41, pages 1650 - 1667-
DESCRIPTION- Angew. Chem. Int. Ed., (20050000), vol. 44, pages 2210 - 2215-
DESCRIPTION- Angew. Chem. Int. Ed., (20080000), vol. 47, pages 2832 - 2835-
DESCRIPTION- Angew. Chem. Int. Ed., (20090000), vol. 48, pages 2411 - 2414-
DESCRIPTION- A. T. BLOMQUISTL. H. LIU, J. Am. Chem. Soc., (19530000), vol. 75, pages 2153 - 2154-
DESCRIPTION- B. C. BORENS. NARAYANL. K. RASMUSSENL. ZHANGH. ZHAOZ. LING. JIAV. V. FOKIN, J. Am. Chem. Soc., (20080000), vol. 130, pages 13518 - 13519-
DESCRIPTION- B. SABAS. SHARMAD. SAWANTB. KUNDU, Synlett, (20070000), pages 1591 - 1594-
DESCRIPTION- C. BARNER-KOWOLLIKM. BUBACKB. CHARLEUXM. L. COOTEM. DRACHET. FUKUDAA. GOTOB. KLUMPERMANA. B. LOWEJ. B. MCLEARY, J. Polym. Sci. Part A, (20060000), vol. 44, pages 5809 - 5831-
DESCRIPTION- C. J. HAWKERK. L. WOOLEY, Science, (20050000), vol. 309, pages 1200 - 1205-
DESCRIPTION- C. NILSSONN. SIMPSONM. MALKOCHM. JOHANSSONE. MALMSTROM, J. Polym. Sci. Part A, (20080000), vol. 46, pages 6969 - 6977-
DESCRIPTION- C. R. BECERK. BABIUCHK. PILZS. HORNIGT. HEINZEM. GOTTSCHALDTU. S. SCHUBERT, Macromolecules, (20090000), vol. 42, pages 2387 - 2394-
DESCRIPTION- D. FOURNIERR. HOOGENBOOMU. S. SCHUBERT, Chem. Soc. Rev., (20070000), vol. 36, pages 1369 - 1380-
DESCRIPTION- D. SAMAROOM. VINODUX. CHENC. M. DRAIN, J. Comb. Chem., (20070000), vol. 9, pages 998 - 1011-
DESCRIPTION- F. SHIJ. P. WALDOY. CHENR. C. LAROCK, Org. Lett., (20080000), vol. 10, pages 2409 - 2412-
DESCRIPTION- G. MOADE. RIZZARDOS. H. THANG, Acc. Chem. Res., (20080000), vol. 41, pages 1133 - 1142-
DESCRIPTION- G. WITTIGA. KREBS, Chem. Ber. Reel., (19610000), vol. 94, pages 3260 - 3275-
DESCRIPTION- H.C. KOLBK.B. SHARPLESS, Drug Discovery Today, (20030000), vol. 8, pages 1128 - 1137-
DESCRIPTION- H. C. KOLBM. G. FINNK. B. SHARPLESS, Angew. Chem., (20010000), vol. 113, pages 2056 - 2075-
DESCRIPTION- H. DURMAZA. DAGO. ALTINTAST. ERDOGANG. HIZALU. TUNCA, Macromolecules, (20070000), vol. 40, pages 7928 - 7933-
DESCRIPTION- H. L. HOLMESR. M. HUSBANDC. C. LEEP. KAWULKA, J. Am. Chem. Soc., (19480000), vol. 70, pages 141 - 142-
DESCRIPTION- J. A. JOHNSONJ. M. BASKINC. R. BERTOZZIJ. F. KOBERSTEINN. J. TURRO, Chem. Commun., (20080000), pages 2052 - 2054-
DESCRIPTION- J. F. LUTZH. SCHLAAD, Polymer, (20080000), vol. 49, pages 817 - 824-
DESCRIPTION- J. GIERLICHG. A. BURLEYP. M. E. GRAMLICHD. M. HAMMONDT. CARELL, Org. Lett., (20060000), vol. 8, pages 4985 - 4988-
DESCRIPTION- J. M. BASKINC. R. BERTOZZI, QSAR Comb. Sci., (20070000), vol. 26, pages 1211 - 1219-
DESCRIPTION- J. M. BASKINJ. A. PRESCHERS. T. LAUGHLINN. J. AGARDP. V. CHANGI. A. MILLERA. LOJ. A. CODELLIC. R. BERTOZZI, Proc. Natl. Acad. Sci. USA, (20070000), vol. 104-
DESCRIPTION- K. C. NICOLAOUS. A. SNYDERT. MONTAGNONG. VASSILIKOGIANNAKIS, Angew. Chem., (20020000), vol. 114, pages 1724 - 1741-
DESCRIPTION- KOLB, Angew. Chem. Int. Ed., (20010000), vol. 40, pages 2004 - 2021-
DESCRIPTION- L. CAMPBELL-VERDUYNP. H. ELSINGAL. MIRFEIZIR. A. DIERCKXB. L. FERINGA, Org. Biomol. Chem., (20080000), vol. 6, pages 3461 - 3463-
DESCRIPTION- L. M. CAMPOSK. L. KILLOPSR. SAKAIJ. M. J. PAULUSSED. DAMIRONE. DROCKENMULLERB.W. MESSMOREC. J. HAWKER, Macromolecules, (20080000), vol. 41, pages 4120 - 4126-
DESCRIPTION- M. LAUTENSW. KLUTEW. TAM, Chem. Rev., (19960000), vol. 96, pages 49 - 92-
DESCRIPTION- N. K. DEVARAJR. WEISSLEDERS. A. HILDERBRAND, Bioconjugate Chem, (20080000), vol. 19, pages 2297 - 2299-
DESCRIPTION- P. BATTIONIO. BRIGAUDH. DESVAUXD. MANSUYT. G. TRAYLOR, Tetrahedron Lett., (19910000), vol. 32, pages 2893 - 2896-
DESCRIPTION- P. L. GOLASN. V. TSAREVSKYB. S. SUMERLINK. MATYJASZEWSKI, Macromolecules, (20060000), vol. 39, pages 6451 - 6457-
DESCRIPTION- Q. WANGT. R. CHANR. HILGRAFV. V. FOKINK. B. SHARPLESSM. G. FINN, J. Am. Chem. Soc., (20030000), vol. 125, pages 3192 - 3193-
DESCRIPTION- S. CHASSAINGA. S. S. SIDOA. ALIXM. KUMARRAJAP. PALE, J. Sommer, Chem. Eur. J., (20080000), vol. 14, pages 6713 - 6721-
DESCRIPTION- S. G. SPAINM. I. GIBSONN. R. CAMERON, J. Polym. Sci. Part A, (20070000), vol. 45, pages 2059 - 2072-
DESCRIPTION- S. S. VAN BERKELA. J. DIRKESM. F. DEBETSF. L. VAN DELFTJ. J. L. CORNELISSENR. J. M. NOLTEF. P. J. RUTJES, ChemBioChem, (20070000), vol. 8, pages 1504 - 1508-
DESCRIPTION- S. S. VAN BERKELA. J. DIRKSS. A. MEEUWISSEND. L. L. PINGENO. C. BOERMANP. LAVERMANF. L. VAN DELFTJ. J. L. CORNELISSENF. P. J. RUTJES, ChemBio- Chem, (20080000), vol. 9, pages 1805 - 1815-
DESCRIPTION- S. T. LAUGHLINJ. M. BASKINS. L. AMACHERC. R. BERTOZZI, Science, (20080000), vol. 320, pages 664 - 667-
DESCRIPTION- V. D. BOCKH. HIEMSTRAJ. H. VAN MAARSEVEEN, Eur. J. Org. Chem., (20060000), pages 51 - 68-
DESCRIPTION- V. LADMIRALG. MANTOVANIG. J. CLARKSONS. CAUETJ. L. IRWIND. M. HADDLETON, J. Am. Chem. Soc., (20060000), vol. 128, pages 4823 - 4830-
DESCRIPTION- V. O. RODIONOVV. V. FOKINM. G. FINN, Angew. Chem., (20050000), vol. 117, pages 2250 - 2255-
DESCRIPTION- W. D. SHARPLESSP. WUT. V. HANSENJ. G. LINDBERG, J. Chem. Educ., (20050000), vol. 82, pages 1833 - 1836-
DESCRIPTION- W. H. BINDERR. SACHSENHOFER, Macromol. Rapid Commun, (20070000), vol. 28, pages 15 - 54-
DESCRIPTION- WINCOTT F. et al., Nucleic Acid Res., (19950000), vol. 23, pages 2677 - 84-
DESCRIPTION- W. SONGY. WANGJ. QUM. M. MADDENQ. LIN, Angew. Chem., (20080000), vol. 120, pages 2874 - 2877-
DESCRIPTION- X. CHEND. A. FOSTERC. M. DRAIN, Biochemistry, (20040000), vol. 43, pages 10918 - 10929-
DESCRIPTION- Y. ZOUJ. YIN, Bioorg. Med. Chem. Lett., (20080000), vol. 18, pages 5664 - 5667-
DESCRIPTION- Z. J.WITCZAKD. LORCHAKN. NGUYEN, Carbohydr. Res., (20070000), vol. 342, pages 1929 - 1933-
DESCRIPTION- Z. LIT. S. SEOJ. JU, Tetrahedron Lett., (20040000), vol. 45, pages 3143 - 3146-
OPPOSITION- Takei Yoshifumo, Et Al, "5'-,3'-Inverted Thymidine-modified Antisense OligodeoxynucleotideTargeting Midkine ITS DESIGN AND APPLICATION FOR CANCER THERAPY", Journal of Biological Chemistry, (20020101), vol. 277, no. 26, pages 23800 - 23806, XP055948890-
OPPOSITION- Ka To Shum, Julian A. Tanner, "Differential Inhibitory Activities and Stabilisation of DNA Aptamers against the SARS Coronavirus Helicase", CHEMBIOCHEM, (20081215), vol. 9, no. 18, doi:10.1002/cbic.200800491, ISSN 1439-4227, pages 3037 - 3045, XP055730769
OPPOSITION- Ugur Sahin, Katalin Karikó, Özlem Türeci, "mRNA-based therapeutics — developing a new class of drugs", Nature Reviews Drug Discovery, Nature Pub. Group, vol. 13, no. 10, doi:10.1038/nrd4278, ISSN 14741776, pages 759 - 780, XP055159205
OPPOSITION- BEIGELMAN L., ET AL., "CHEMICAL MODIFICATION OF HAMMERHEAD RIBOZYMES. CATALYTIC ACTIVITY AND NUCLEASE RESISTANCE.", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (19951027), vol. 270., no. 43., doi:10.1074/jbc.270.43.25702, ISSN 0021-9258, pages 25702 - 25708., XP000601905
SEARCH- AFAF H. EL-SAGHEER ET AL, "Click Nucleic Acid Ligation: Applications in Biology and Nanotechnology", ACCOUNTS OF CHEMICAL RESEARCH., US, (20120322), vol. 45, no. 8, doi:10.1021/ar200321n, ISSN 0001-4842, pages 1258 - 1267, XP055454304 [A] 1-9,14-17 * figure 10 *
SEARCH- TOBIAS SANTNER ET AL, "Efficient Access to 3'-Terminal Azide-Modified RNA for Inverse Click-Labeling Patterns", BIOCONJUGATE CHEMISTRY, US, (20131220), vol. 25, no. 1, doi:10.1021/bc400513z, ISSN 1043-1802, pages 188 - 195, XP055574407 [A] 1-9,14-17 * Scheme 1; figure 1; table 1 *
SEARCH- ANUP M JAWALEKAR ET AL, "Oligonucleotide tagging for copper-free click conjugation", MOLECULES: A JOURNAL OF SYNTHETIC ORGANIC AND NATURAL PRODUCT CHEMISTRY, M D P I AG, CH, (20130624), vol. 18, no. 7, doi:10.3390/MOLECULES18077346, ISSN 1420-3049, pages 7346 - 7363, XP002720935 [A] 1-9,14-17 * Scheme 6; figures 2,3 *

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents