Direct Compression Formulation And Process - EP3366283

The patent EP3366283 was granted to Novartis on Sep 1, 2021. The application was originally filed on Jan 17, 2005 under application number EP18165545A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3366283

NOVARTIS
Application Number
EP18165545A
Filing Date
Jan 17, 2005
Status
Granted And Under Opposition
Jul 30, 2021
Grant Date
Sep 1, 2021
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions (6)

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HOFFMANN EITLEJun 1, 2022-WITHDRAWN
HAMM & WITTKOPPMay 30, 2022-WITHDRAWN
WUESTHOFF & WUESTHOFF PATENTANWALTE PARTG MBBMay 30, 2022SONNENHAUSERWITHDRAWN
INSTONE TERRY READ HOWARD GRAHAMAPPLEYARD LEESMay 23, 2022APPLEYARD LEESWITHDRAWN
D YOUNGMay 19, 2022-WITHDRAWN
COOKESep 28, 2021ELKINGTON AND FIFEWITHDRAWN

Patent Citations (92) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
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DESCRIPTIONWO9961431
DESCRIPTIONWO9967278
DESCRIPTIONWO9967279
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OPPOSITIONEP1715893
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SEARCHJP2003327532
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SEARCHWO0034241

Non-Patent Literature (NPL) Citations (50) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- A.H.Kibbe, Handbook of pharmaceutical excipients, 3rd edition, Published by: American Pharmaceutical Association-
DESCRIPTION- British Pharmacopoeia, (19880000), vol. II, page 895-
DESCRIPTION- "Chapter 3: SIZE REDUCTION", H.A.Lieberman, L.Lachman, J.B.Schwartz, "Pharmaceutical dosage forms: volume 2, 2nd edition-
DESCRIPTION- Diabetes, (19980000), vol. 47, pages 1253 - 1258-
DESCRIPTION- Expert Opinion Investig Drugs, (20030400), vol. 12, no. 4, pages 623 - 33-
DESCRIPTION- H.U. DEMUTH et al., J. Enzyme Inhibition, (19880000), vol. 2, pages 129 - 142-
DESCRIPTION- Raymond C Rowe, Handbook of Pharmaceutical Excipients (4th edition), Publisher: Science and Practice-
DESCRIPTION- T. ALLEN, Particle Size Measurement, 5th Ed. ,, Chapman & Hall, (19970000), vol. 1, page 178-
DESCRIPTION- WALLACE T. ASHTON, Bioorganic & Medicinal Chemistry Letters, (20040000), vol. 14, pages 859 - 863-
EXAMINATION- VILLHAUER E B ET AL, "1-ÄÄ(3-HYDROXY-1-ADAMANTYL)AMINOÜACETYLÜ-2-CYANO-(S)-PYRROLIDINE: A POTENT, SELECTIVE, AND ORALLY BIOAVAILABLE DIPEPTIDYL PEPTIDASE IV INHIBITOR WITH ANTIHYPERGLYCEMIC PROPERTIES", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (20030101), vol. 46, no. 13, doi:10.1021/JM030091L, ISSN 0022-2623, pages 2774 - 2789, XP001165747
OPPOSITION- "A. Direct Compression", Dilip M Parikh, Handbook Pharmaceutical Granulation Technology, (19970101), vol. 81, page 102, XP055565064-
OPPOSITION- AHMAD et al., "Effect of Moisture on the Stability of Packaged Paracetamol Tablet Formulations", Pakistan J. Pharm. Sci., (20030000), vol. 16, no. 2, pages 13 - 16, XP002572514-
OPPOSITION- AKERS M. et al., "Preformulation Testing of Solid Oral Dosage Form Drugs", Canadian J Pharm Sci, (19760000), vol. 11, no. 1, pages 1 - 10, XP055565262-
OPPOSITION- Alan Rawle, "BASIC PRINCIPLES OF PARTICLE SIZE ANALYSIS", Malvern Technical Paper, UK , (19930101), pages 1 - 8, XP055009141-
OPPOSITION- Anonymous, "Dragees, rund", Gelbe Liste Identa, Medi Media, (20040101), pages 2 - 83, XP055933117-
OPPOSITION- ANSEL et al., PHARMACEUTICAL DOSAGE FORMS AND DRUG DELIVERY SYSTEMS, 7TH ED., (19990101), pages 196, 209, 216 - 217, ISBN 978-0-683-30572-2, XP055565061-
OPPOSITION- AULTON M.E., PHARMACEUTICS. THE SCIENCE OF DOSAGE FORM DESIGN, 2nd ED., (20020101), pages 166 - 180, 405, XP055565073-
OPPOSITION- AULTON M.E., PHARMACEUTICS. THE SCIENCE OF DOSAGE FORM DESIGN, 2nd ED., (20020101), pages 431 - 436, ISBN 978-0-443-05517-1, XP055570278-
OPPOSITION- AULTON M.E., PHARMACEUTICS. THE SCIENCE OF DOSAGE FORM DESIGN, 2nd ED., (20020101), pages 6 - 7, ISBN 978-0-443-05517-1, XP055565127-
OPPOSITION- Aulton M. E., "Powder Flow Properties", PHARMACEUTICS: THE SCIENCE OF DOSAGE FORM DESIGN. 1st Ed., Churchill Livingstone, (19860101), pages 247 - 607, 647-661, XP055933122-
OPPOSITION- "Avicel®", DuPont - Product specification, (20050101), URL: https://www.pharma.dupont.com/pharmaceutical-products/avicelr-for-solid-dose-forms.html, XP055570284-
OPPOSITION- "Avicel® PH-200", Product Overview, (20050101), pages 1 - 2, XP055926782-
OPPOSITION- "Chapter 1 and 6", Harry G Brittain, Physical Characterization of Pharmaceutical Solids, (19950101), pages 1-35, 157 - 186, XP055565275-
OPPOSITION- Deodatt A. Wadke, "Chapter 1 - Preformulation Testing", Pharmaceutical Dosage Forms: Tablets, Volume 1, 2nd ed. , (19890101), pages 1 - 24, XP055416092-
OPPOSITION- Dilip M Parikh, "A. Direct Compression", Handbook Pharmaceutical Granulation Technology vol 81, (19970101), page 102, XP055565064-
OPPOSITION- Edward Rudnic, Joseph B Schwarz, "Chapter 92 (passage)", REMINGTON: THE SCIENCE AND PRACTICE OF PHARMACY, 19th ed., (19950101), pages 595, 1615 - 1627, XP055926744-
OPPOSITION- Gelbe Liste Identa 2004, 15 Ausgabe, (2004), pages 1 - 84, XP055565221-
OPPOSITION- "General Monographs - Tablets", British Pharmacopoeia, (19931201), vol. II, page 753, XP055565110-
OPPOSITION- Gilbert S. Banker, et al., Drugs and Pharmaceutical Sciences. Modern Pharmaceutics., (19900101), vol. 40, pages 355 - 358, 404, 405, ISBN 0-8247-7499-X, XP055570198-
OPPOSITION- Gilbert S. Banker, Et Al, "Tablet Dossage Forms", Drugs and Pharmaceutical Sciences. Modern Pharmaceutics. Volume 40, Marcel Dekker , (19900101), pages 355 - 405, ISBN 0-8247-7499-X, XP055570198-
OPPOSITION- Hunnius Pharmazeutisches Worterbuch, 8th ed., (19980101), pages 424 - 425, XP055565291-
OPPOSITION- Kaneniwa Nobuyoshi, Kanji Imagawa, Jun-Ichi Ichikawa, "The effect of particle size on the compaction properties and compaction mechanism of sulfadimethoxine and sulfaphenazole", Chem. Pharm. Bull., (19880101), vol. 36, no. 7, pages 2531 - 2537, XP055926787-
OPPOSITION- Kibbe, A. H, Et Al, "cellulose microcrystalline", Handbook of Pharmaceutical Excipients, (20000101), pages 102 - 285, 305-308, 501-504, XP055566535-
OPPOSITION- Kibbe et al., Handbook of Pharmaceutical Excipients, (20000101), pages 102-106, 276 - 285, 305-308, 500-504, XP055566535-
OPPOSITION- Lachman et al., The Theory and Practice of Industrial Pharmacy, (19700101), pages 305 - 319, XP055297952-
OPPOSITION- Lachmann et al., The Theory and Practice of Industrial Pharmacy, (19760101), page 221, XP055308588-
OPPOSITION- LIEBERMAN H.A. ET AL, PHARMACEUTICAL DOSAGE FORMS - TABLETS, (19800101), vol. 1, pages 3 - 4, XP003028605-
OPPOSITION- LIEBERMAN H.A. ET AL, "PHARMACEUTICAL DOSAGE FORMS, Tablets", PHARMACEUTICAL DOSAGE FORMS-TABLETS, XX , XX , (19800101), vol. 1, pages I - 3-4, XP003028605-
OPPOSITION- L. Lachman Et Al., William C. Gunsel Et Al, "Tablets - Chapter 12", The Theory and Practice of Industrial Pharmacy, (19700101), pages 305 - 327, XP055297952-
OPPOSITION- Martin et al., Physical Pharmacy: Physical Chemical Principles in the Pharmaceutical Sciences, 4th Edition, (1993), pages 331, 423 - 427, 429-436, XP003028604-
OPPOSITION- M. E. Aulton, Pharmaceutics: The Science of Dosage Form Design, (19880101), pages 247-249, 555-557, 564-580, 600 - 607, 647-661, ISBN 0-443-03643-8, XP055570217-
OPPOSITION- "Mesh", ROMPP-LEXIKON CHEMIE, (19980101), page 2598, XP055565247-
OPPOSITION- Milo Gibaldi, Biopharmaceutics and Clinical Pharmacokinetics, fourth edition, (19910101), page 51, XP055355462-
OPPOSITION- Nobuyoshi Kaneniwa, Kanji Imagawa, Jun-Ichi Ichikawa, "The effect of particle size on the compaction properties and compaction mechanism of sulfadimethoxine and sulfaphenazole", Chem. Pharm. Bull., (19880101), vol. 36, no. 7, pages 2531 - 2537, XP055926787-
OPPOSITION- Wadke Deodatt A, Abu T, M. Serajuddin, Harold Jacobson, Ralph F. Shangraw, "Chapters 1 and 4", Wadke Deodatt A, Abu T, M. Serajuddin, Harold Jacobson, Ralph F. Shangraw, Lieberman et al., Pharmaceutical Dosage Forms: Tablets, 2nd ed., (19890101), vol. 1, pages 1-24, 195 - 220, XP055926649-
OPPOSITION- "WHY DETERMINATION OF SIZES IS NOT STRAIGHT FORWARD", KARIN LILTORP, DETERMINATION OF PARTICLE SIZES, (20140101), pages 10 - 29, 54, 55, ISBN 978-87-7145-657-8, XP003035359-
OPPOSITION- CRAIG, "The mechanisms of drug release from solid dispersions in water- soluble Polymers", International Journal of Pharmaceutics, (20020000), vol. 231, doi:10.1016/S0378-5173(01)00891-2, pages 131 - 144, XP055067696
OPPOSITION- VILLHAUER E B, et al., "1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties", Journal of Medicinal Chemistry, US , (20030101), vol. 46, no. 13, doi:10.1021/jm030091l, ISSN 0022-2623, pages 2774 - 2789, XP002497964
OPPOSITION- Villhauer et al., "(Supporting information to) 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties", Journal of Medicinal Chemistry, US , (20030101), vol. 46, no. 13, doi:10.1021/JM030091L, ISSN 0022-2623, pages 1 - 18, XP055565090
OPPOSITION- COHEN et al., "The Development of USP Dissolution and Drug Release Standards", Pharmaceutical Research, (19900000), vol. 7, no. 1 0, doi:10.1023/A:1015922629207, pages 983 - 987, XP009120018

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