Bifidobacterium Longum And Hippocampal Bdnf Expression - EP3398446

The patent EP3398446 was granted to Nestec on Feb 19, 2020. The application was originally filed on Apr 8, 2009 under application number EP18172784A. The patent is currently recorded with a legal status of "Revoked".

EP3398446

NESTEC
Application Number
EP18172784A
Filing Date
Apr 8, 2009
Status
Revoked
Oct 20, 2023
Grant Date
Feb 19, 2020
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

MORINAGA MILK INDUSTRYNov 18, 2020VOSSIUS & PARTNER PATENTANWALTE RECHTSANWALTE MBB -

Patent Citations (13) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
OPPOSITIONEP2110028
OPPOSITIONEP2289527
OPPOSITIONEP2470188
OPPOSITIONEP3072398
OPPOSITIONWO0041707
OPPOSITIONWO2004098622
OPPOSITIONWO2007093619
OPPOSITIONWO2010008278
OPPOSITIONWO2011023689
SEARCHJP2008081434
SEARCHWO2004098622
SEARCHWO2007093619
SEARCHWO9611014

Non-Patent Literature (NPL) Citations (58) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- ABE, Food Style, (20020900), vol. 6, no. 9, pages 62 - 67, XP055756517-
OPPOSITION- BLEI A. T. et al, "Hepatic encephalopathy", Am J Gastroenterol, (20010701), vol. 96, no. 7, pages 1968 - 1976, XP027391873-
OPPOSITION- CREED, "Psychological treatments of the irritable bowel syndrome: a review", Gut, (19890000), vol. 30, pages 1601 - 1609, XP055569232-
OPPOSITION- "Depress", Judy Pearsall, The New Oxford Dictionary of English, OXFORD UNIVERSITY PRESS, (19980000), page 74, 496, 1839, XP055756515-
OPPOSITION- EBISAWA E. et al, "Experience in Dosing Obstetrical and Gynecological Inpatients with Bifidobacterium-ContsAning Yogurt “La Sante”", Clinical Nutrition ( Japan ), (19850600), vol. 66, no. 7, pages 805 - 810, XP055756519-
OPPOSITION- FANIGLIULO L. et al, "Role of gut microflora and probiotic effects in die irritable bowel syndrome", Acta Biomed, (20060000), vol. 77, pages 85 - 89, XP055756346-
OPPOSITION- FUKUSHIMA N. et al, "Present day life and constipation : according to the questionnaire", The annual report of the Kyoritu College of Pharmacy, (19910000), vol. 1991, no. 36, pages 1 - 11, XP055756521-
OPPOSITION- INOUE, "PD22-7 Bifidobacterium longum (BB 536)", Japan Gastroenterology Society Journal, (20060700), vol. 103, page A611, XP055756524-
OPPOSITION- KURINA, "Depression and anxiety in people with inflammatory bowel disease", J. Epidemiol. Community Health, (20010000), vol. 55, pages 716 - 720, XP008103970-
OPPOSITION- O'MAHONY, "Is Bifidobacterium a more effective probiotic therapy than Lactobacillus for patients with irritable bowel syndrome?", Nature Clinical Practice, (20050000), vol. 2, no. 7, pages 304 - 305, XP055535862-
OPPOSITION- RISTIC Gordana et al, "EFEKAT FUNKCIONALNOG MLECNOG PROIZVODA OBOGACENOG KULTUROM Bifidobacterium longum BB536 U TRETMANU GOJAZNOSTI", Prehrambena industrija, (20020000), vol. 1-2, pages 81 - 84, XP055535678-
OPPOSITION- SHELTON C. I., "Diagnosis and Management of Anxiety Disorders", Journal of the American Osteopathic, (20040301), vol. 104, no. 3, pages S2 - S5, XP055569342-
OPPOSITION- STEWART, "Minimal hepatic encephalopathy", Nature Clinical Practice. Gastroenterol & Hepatology, (20071200), vol. 4, no. 12, pages 677 - 685, XP055568947-
OPPOSITION- SUGAYA, "Effect of lactulose/lactic acid bacteria administration on fecal microbiota, nitrogen compounds and organic acids in patients with liver cirrhosis", Dokkyo Journal of Medical Sciences, (19870106), vol. 2, no. 2, pages 227 - 233, XP055756520-
OPPOSITION- XIAO, "Effect of probiotic Bifidobacterium longum BBS36 in relieving clinical symptoms and modulating plasma cytokine levels of Japanese cedar pollinosis during the pollen season. A randomized double-blind, placebo-controlled trial", J Investig Allergol Clin Immunol, (20060000), vol. 16, no. 2, pages 86 - 93, XP002500162-
OPPOSITION- YAESHIMA T. et al, "Bifidobacterium longum BB 536", Journal of Nutrition Food, (19980000), vol. 1, no. 3/4, pages 1 - 6, XP0055568941-
OPPOSITION- JOHANSSON, "Study of Expression Patterns and Levels of Neurotrophins and Neurotrophin Receptors in Ulcerative Colitis", Inflamm Bowel Dis, (20070000), vol. 13, no. 4, pages 398 - 409, XP055569368
OPPOSITION- NARDUCCI F. et al, "Increased colonic motility during exposure to a stressful situation", Digestive Diseases and Sciences, (19850000), vol. 30, no. 1, pages 40 - 44, XP055536127
OPPOSITION- GRUENWALD J. et al, "Effect of a Probiotic Multivitamin Compound on Stress and Exhaustion", Advances in Therapy, (20020501), vol. 19, no. 3, pages 141 - 150, XP055535693
OPPOSITION- MALAGUARNERA M. et al, "Bifidobacterium longum with Fructo-Oligosaccharide (FOS) Treatment in Minimal Hepatic Encephalopathy: A Randomized, Double-Blind, Placebo-Controlled Study", Dig Dis Sci, (20070328), vol. 52, no. 11, pages 3259 - 3265, XP019550473
OPPOSITION- STANGE, "European evidence-based Consensus on the diagnosis and management of ulcerative colitis: Definitions and diagnosis", Journal of Crohn's and Colitis, (20080300), vol. 2, pages 1 - 23, XP022452896
OPPOSITION- MUNOZ, "Hepatic Encephalopathy", Med Clin N Am, (20080618), vol. 92, no. 4, pages 795 - 812, XP008116796
OPPOSITION- LOGAN A. C. et al, "Major depressive disorder: probiotics may be an adjuvant therapy", Medical Hypotheses, (20050000), vol. 64, no. 3, pages 533 - 538, XP004691105
OPPOSITION- DIOP et al, "Probiotic food supplement reduces stress-induced gastrointestinal symptoms in volunteers: a double-blind, placebo-controlled, randomized trial", Nutrition Research, (20080115), vol. 28, no. 1, pages 1 - 5, XP022420472
OPPOSITION- KOBAYASHI, "Serum brain-derived neurotrophic factor (BDNF) levels in patients with panic disorder: As a biological predictor of response to group cognitive behavioral therapy", Progress in Neuro-Psychopharmacology & Biological Psychiatry, (20050000), vol. 29, pages 658 - 663, XP004962035
OPPOSITION- MERTZ, "Regional cerebral activation in irritable bowel syndrome and control subjects with painful and nonpainful rectal distention", Gastroenterology, (20000000), vol. 118, pages 842 - 8, XP005138571
OPPOSITION- BANCROFT, "The effect of challenge and trickle Trichuris muris infections on the polarisation of the immune response", Int J Parasit, (20010000), vol. 31, pages 1627 - 1637, XP055569273
OPPOSITION- KAREGE F. et al, "Decreased serum brain-derived neurotrophic factor levels in major depressed patients", Psychiatry Research, (20020315), vol. 109, pages 143 - 148, XP008120219
OPPOSITION- RASMUSSON, "Downregulation of BDNF mRNA in the Hippocampal Dentate Gyrus after Re-exposure to Cues Previously Associated with Footshock", Neuropsychopharmacology, (20020101), vol. 27, no. 2, pages 133 - 142, XP055568960
OPPOSITION- KANAZAWA M. et al, "Patients and Nonconsulters with Irritable Bowel Syndrome Reporting a Parental History of Bowel Problems Have More Impaired Psychological Distress", Digestive Diseases and Sciences, (20040601), vol. 49, no. 6, pages 1046 - 1053, XP055569157
OPPOSITION- BALLONGUE, "Action sur la flore intestinale de laits fermentes au Bifidobacterium", Lait, (19930000), vol. 73, pages 249 - 256, XP055535845
OPPOSITION- O'MAHONY, "Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles", Gastroenterology, (20050000), vol. 128, pages 541 - 551, XP002479504
OPPOSITION- LONGSTRETH, "Functional Bowel Disorders", Gastroenterology, (20060000), vol. 130, pages 1480 - 1491, XP005442445
OPPOSITION- PINTO-SANCHEZ M. I. et al, "ProbioticBifidobacterium longumNCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome", Gastroenterology, (20170505), vol. 153, no. 2, pages 448 - 459, XP085142219
OPPOSITION- GOVINDARAJAN A. et al, "Transgenic brain-derived neurotrophic factor expression causes both anxiogenic and antidepressant effects", PNAS, (20060829), vol. 103, no. 35, pages 13208 - 13213, XP055756525
OPPOSITION- USHIROYAMA T. et al, "A Pilot Study of a Kampo Formula, EH0202, with Intriguing Results for Menopausal Symptoms", Journal of Alternative and Complementary Medicine (JACM), (20040101), vol. 10, no. 2, pages 397 - 399, XP008085281
OPPOSITION- ROTH, "Mindfulness-Based Stress Reduction and Health-Related Quality of Life: Findings From a Bilingual Inner-City Patient Population", Psychosom Med, (20040000), vol. 66, pages 113 - 123, XP055535943
OPPOSITION- SAKATA, "Unification of Bifidobacterium infantis and Bifidobacterium suis as Bifidobacterium longum", International Journal of Systematic and Evolutionary Microbiology, (20020000), vol. 52, pages 1945 - 1951, XP055394343
OPPOSITION- ABE, "Stability of bifidobacteria in powdered formula", International Journal of Food Science & Technology, (20090313), vol. 44, pages 718 - 724, XP055535855
OPPOSITION- MATSUMOTO, "Oral administration of Bifidobacterium longum prevents gut-derived Pseudomonas aeruginosa sepsis in mice", J Appl Microbiol, (2080301), vol. 104, no. 3, pages 672 - 680, XP002521960
OPPOSITION- KABEIR, "Growth of Bifidobacterium longum 88536 in medida (fermented cereal porridge) and their survival during refrigerated storage", Letters in Applied Microbiology, (20050000), vol. 41, pages 125 - 131, XP055536005
OPPOSITION- GUYONNET D. et al, "Fermented milk containing Bifidobacterium lactis DN-173 010 improved self-reported digestive comfort amongst a general population of adults. A randomized, open-label, controlled, pilot study", Journal of Digestive Diseases, (20090201), vol. 10, no. 1, pages 61 - 70, XP002579815
OPPOSITION- SUDO N. et al, "Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice", Journal of Physiology, (20040624), vol. 558, no. 1, pages 263 - 275, XP055352332
OPPOSITION- EUTAMENE H. et al, "Role of probiotics in correcting abnormalities of colonic flora induced by stress", Gut, (20070000), vol. 56, no. 11, pages 1495 - 1497, XP055756529
OPPOSITION- BENNETT, "Level of chronic life stress predicts clinical outcome in irritable bowel syndrome", Gut, (19980000), vol. 43, pages 256 - 61, XP055569262
OPPOSITION- MAYER, "The neurobiology of stress and gastrointestinal disease", Gut, (20000000), vol. 47, pages 861 - 869, XP055569199
OPPOSITION- MERTZ, "Role of the brain and sensory pathways in gastrointestinal sensory disorders in humans", Gut, (20020000), vol. 51, no. Suppl 1, pages i29 - i33, XP055535948
OPPOSITION- USHIROYAMA, "Clinical efficacy of EH0202, a Kampo formula, on the health of middle-aged women", American Journal of Chinese Medicine (AJCM), (20040101), vol. 32, no. 5, pages 755 - 770, XP008085282
OPPOSITION- MONNIKES H. et al, "Role of Stress in Functional Gastrointestinal Disorders", Digestive Diseases and Sciences, (20010101), vol. 19, no. 3, pages 201 - 211, XP055569292
OPPOSITION- JONES M. P. et al, "Functional Gastrointestinal Disorders: An Update for the Psychiatrist", Psychosomatics, (20070300), vol. 48, no. 2, pages 93 - 102, XP055756530
OPPOSITION- RIOS, "Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity", Molecular Endocrinology, (20010000), vol. 15, no. 10, pages 1748 - 1757, XP002455825
OPPOSITION- ARAYA-KOJIMA, "Inhibitory Effects of Bifidobacterium longum BB536 on Harmful Intestinal Bacteria", Bifidobacteria Microflora, (19950000), vol. 14, no. 2, doi:10.12938/bifidus1982.14.2_59, pages 59 - 66, XP055535867
OPPOSITION- ALTMANN, "Genome Analysis and Characterisation of the Exopolysaccharide Produced by Bifidobacterium longum subsp. /ongum 3562 ™", PLOS one, (20160000), XP055569077
OPPOSITION- SMITH, "Stress and Glucocorticoids Affect the Expression of Brain-Derived Neurotrophic Factor and Neurotrophin-3 mRNAs in the Hippocampus", The Journal of Neuroscience, (19950000), vol. 15, no. 3, pages 1768 - 1777, XP055569276
OPPOSITION- XIAO, "Bifidobacterium longum BB 536", Japanese Journal of Lactic Acid Bacteria, (20070000), vol. 18, no. 1, pages 31 - 36, XP055756235
OPPOSITION- CREED, "Health-related quality of life and health care costs in severe, refractory irritable bowel syndrome", Annals of Internal Medicine, (20010000), vol. 134, no. 9, pages 860 - 866, XP055536137
OPPOSITION- ABE, "Effects of storage temperature and water activity on the survival of bifidobacteria in powder form", International Journal of Dairy Technology, (20090500), vol. 62, no. 2, pages 234 - 239, XP055536012
SEARCH- LOGAN A. C et al, "Major depressive disorder: probiotics may be an adjuvant therapy", (20050101), vol. 64, no. 3, ISSN 0306-9877, pages 533 - 538, XP004691105 [A] 1-15 * the whole document *

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents