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| OPPOSITION | - Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai, "Chapter 7: Immune receptors and signal transduction", Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai, Abul K. Abbas • Andrew H. Lichtman • Shiv Pillai, Cellular and molecular immunology, 10th ed., Elsevier, (20220101), pages 151 - 186, ISBN 978-0-323-75748-5, XP009556905 | - |
| OPPOSITION | - Anonymous, "Pidilizumab (CT-011)", Cure Tech, (20070101), XP093209598 | - |
| OPPOSITION | - Anonymous, "Pidilizumab - CureTech", Adis Insight, (20231105), XP093211657 | - |
| OPPOSITION | - Anonymous, "Pidilizumab Overview", Creative Biolabs, (20240101), Creative Biolabs, URL: https://www.creativebiolabs.net/pidilizumab-overview.htm, XP093209607 | - |
| OPPOSITION | - Anonymous, "pidilizumab", PUBCHEM SUBSTANCE, (20141113), Database accession no. 223366026, XP093196656 | - |
| OPPOSITION | - Anonymous, "Product Overview ", Cure Tech, (20170708), Cure Tech, URL: https://web.archive.org/web/20170708085045/http://www.curetechbio.com/technology/product-overview/, XP093209603 | - |
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| OPPOSITION | - Ito Akihiro, Handa Kazuko, Withers Donald A, Satoh Makoto, Hakomori Sen-Itiroh, "Binding speci¢city of siglec7 to disialogangliosides of renal cell carcinoma: possible role of disialogangliosides in tumor progression", FEBS Letters, (20010101), vol. 498, pages 116 - 120, XP055948829 | - |
| OPPOSITION | - Lowe Derek, "Medivation Decides That Their Drug Isn't What They Thought", Science, AAAS, (20160126), pages 1 - 10, Science, AAAS, URL: https://www.science.org/content/blog-post/medivation-decides-their-drug-isn-t-they-thought, XP093171471 | - |
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| OPPOSITION | - Marie Vincent; Anne Bessard; Denis Cochonneau; Géraldine Teppaz; Véronique Solé; Mike Maillasson; Stéphane Birklé; Laure Garrigue‐Antar; Agnès Quéméner; Yannick Jacques, "Tumor targeting of the IL‐15 superagonist RLI by an anti‐GD2 antibody strongly enhances its antitumor potency", International Journal of Cancer, John Wiley & Sons, Inc., US, US , (20130225), vol. 133, no. 3, doi:10.1002/ijc.28059, ISSN 0020-7136, pages 757 - 765, XP071287855 | |
| OPPOSITION | - Marie Vincent, Anne Bessard, Denis Cochonneau, Géraldine Teppaz, Véronique Solé, Mike Maillasson, Stéphane Birklé, Laure Garrigue-Antar, Agnès Quéméner, Yannick Jacques, "Tumor targeting of the IL-15 superagonist RLI by an anti-GD2 antibody strongly enhances its antitumor potency", International Journal of Cancer, Union Internationale Centre le Cancer., (20130801), vol. 133, no. 3, doi:10.1002/ijc.28059, ISSN 00207136, pages 757 - 765, XP055151554 | |
| OPPOSITION | - Schnaar Ronald L., "Gangliosides as Siglec ligands", Glycoconjugate Journal, Chapman & Hall, Boston, Boston , (20230401), vol. 40, no. 2, doi:10.1007/s10719-023-10101-2, ISSN 0282-0080, pages 159 - 167, XP093196624 | |
| OPPOSITION | - Crespo Joel, Sun Haoyu, Welling Theodore H, Tian Zhigang, Zou Weiping, "T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment", Current Opinion in Immunology, ELSEVIER, OXFORD., GB, GB , (20130401), vol. 25, no. 2, doi:10.1016/j.coi.2012.12.003, ISSN 0952-7915, pages 214 - 221, XP093211656 | |
| OPPOSITION | - Motz Greg t., Coukos George, "Deciphering and Reversing Tumor Immune Suppression", Immunity, Cell Press, AMSTERDAM, NL, AMSTERDAM, NL , (20130701), vol. 39, no. 1, doi:10.1016/j.immuni.2013.07.005, ISSN 1074-7613, pages 61 - 73, XP055944165 | |
| OPPOSITION | - Akihiro Ito; Kazuko Handa; Donald A. Withers; Makoto Satoh; Sen-itiroh Hakomori, "Binding specificity of siglec7 to disialogangliosides of renal cell carcinoma: possible role of disialogangliosides in tumor progression", FEBS Letters, ELSEVIER, AMSTERDAM., NL, NL , (20010820), vol. 504, doi:10.1016/S0014-5793(01)02734-X, ISSN 0014-5793, pages 82 - 86, XP071242541 | |
| OPPOSITION | - Ira Mellman, George Coukos, Glenn Dranoff, "Cancer immunotherapy comes of age", Nature, ¬Macmillan Journals Ltd., etc.|, (20110101), vol. 480, no. 7378, doi:10.1038/nature10673, ISSN 00280836, pages 480 - 489, XP055054665 | |
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| OPPOSITION | - Melero Ignacio; Berman David M.; Aznar M. Angela; Korman Alan J.; Gracia José Luis Pérez; Haanen John, "Evolving synergistic combinations of targeted immunotherapies to combat cancer", Nature Reviews Cancer, Nature Pub. Group, London, London , (20150724), vol. 15, no. 8, doi:10.1038/nrc3973, ISSN 1474-175X, pages 457 - 472, XP037922457 | |
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| OPPOSITION | - MIERLO VAN G J D, ET AL., "CD40 STIMULATION LEADS TO EFFECTIVE THERAPY OF CD40- TUMORS THROUGH INDUCTION OF STRONG SYSTEMIC CYTOTOXIC T LYMPHOCYTE IMMUNITY", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20020416), vol. 99, no. 08, doi:10.1073/pnas.082107699, ISSN 0027-8424, pages 5561 - 5566, XP008046904 | |
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| OPPOSITION | - Albuquerque Aline De, Da Silva Junior Haroldo Cid; Sartori Geraldo Rodrigues; Martins Da Silva João Hermínio, "Computationally-obtained structural insights into the molecular interactions between Pidilizumab and binding partners DLL1 and PD-1", JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ADENINE PRESS, NEW YORK, NY, US, US , (20220922), vol. 40, no. 14, doi:10.1080/07391102.2021.1885492, ISSN 0739-1102, pages 6450 - 6462, XP093171502 | |
| OPPOSITION | - Chern Siang Lee, Mark Cragg, Martin Glennie, Peter Johnson, "Novel antibodies targeting immune regulatory checkpoints for cancer therapy", British Journal of Clinical Pharmacology, (20130801), vol. 76, no. 2, doi:10.1111/bcp.12164, ISSN 03065251, pages 233 - 247, XP055151740 | |
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| OPPOSITION | - Jedd D. Wolchok; F. Stephen Hodi; Jeffrey S. Weber; James P. Allison; Walter J. Urba; Caroline Robert; Steven J. O'Day; Axel Hoos; Rachel Humphrey; David M. Berman; Nils Lonberg; Alan J. Korman, "Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma", Annals of the New York Academy of Sciences, New York Academy of Sciences., US, US , (20130617), vol. 1291, no. 1, doi:10.1111/nyas.12180, ISSN 0077-8923, pages 1 - 13, XP071409026 | |
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| OPPOSITION | - P. Yu, J. C. Steel, M. Zhang, J. C. Morris, T. A. Waldmann, "Simultaneous Blockade of Multiple Immune System Inhibitory Checkpoints Enhances Antitumor Activity Mediated by Interleukin-15 in a Murine Metastatic Colon Carcinoma Model", Clinical Cancer Research, Association for Cancer Research, (20101215), vol. 16, no. 24, doi:10.1158/1078-0432.CCR-10-1966, ISSN 10780432, pages 6019 - 6028, XP055123618 | |
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| OPPOSITION | - Kankana Bardhan, Theodora Anagnostou, Vassiliki A. Boussiotis, "The PD1:PD-L1/2 Pathway from Discovery to Clinical Implementation", Frontiers in Immunology, vol. 7, doi:10.3389/fimmu.2016.00550, XP055488786 | |
| OPPOSITION | - Menard Laurence C., Fischer Paul, Kakrecha Bijal, Linsley Peter S., Wambre Erik, Liu Maochang C., Rust Blake J., Lee Deborah, Penhallow Becky, Manjarrez Orduno Nataly, Nadler Steven G., "Renal Cell Carcinoma (RCC) Tumors Display Large Expansion of Double Positive (DP) CD4+CD8+ T Cells With Expression of Exhaustion Markers", Frontiers in Immunology, Frontiers Media, Lausanne, CH, Lausanne, CH , (20181126), vol. 9, doi:10.3389/fimmu.2018.02728, ISSN 1664-3224, XP093209609 | |
| OPPOSITION | - Junker Fabian, Gordon John, Qureshi Omar, "Fc Gamma Receptors and Their Role in Antigen Uptake, Presentation, and T Cell Activation", Frontiers in Immunology, (20200101), vol. 11, doi:10.3389/fimmu.2020.01393, page 1393, XP055782877 | |
| OPPOSITION | - Philippova Julia, Shevchenko Julia, Sennikov Sergey, "GD2-targeting therapy: a comparative analysis of approaches and promising directions", Frontiers in Immunology, Frontiers Media, Lausanne, CH, Lausanne, CH , vol. 15, doi:10.3389/fimmu.2024.1371345, ISSN 1664-3224, XP093196619 | |
| OPPOSITION | - Hardy Britta, Indjiia Leonora, Rodionov Galina, Raiter Annat, Inbal Aida, "Treatment with BAT monoclonal antibody decreases tumor burden in a murine model of leukemia/lymphoma", International journal of oncology, Demetrios A. Spandidos Ed. & Pub, GR, GR , (20010101), vol. 19, doi:10.3892/ijo.19.5.897, ISSN 1019-6439, pages 897 - 902, XP093196646 | |
| OPPOSITION | - Xiaoyun Zhu, Warren D. Marcus, Wenxin Xu, Hyung-Il Lee, Kaiping Han, Jack O. Egan, Jason L. Yovandich, Peter R. Rhode, Hing C. Wong, "Novel Human Interleukin-15 Agonists", The Journal of Immunology, Williams & Wilkins Co., US, US , (20090915), vol. 183, no. 6, doi:10.4049/jimmunol.0901244, ISSN 0022-1767, pages 3598 - 3607, XP055732478 | |
| OPPOSITION | - Miyazaki Keiko, Sakuma Keiichiro, Kawamura Yuki I., Izawa Mineko, Ohmori Katsuyuki, Mitsuki Motoaki, Yamaji Toshiyuki, Hashimoto Yasuhiro, Suzuki Akemi, Saito Yukio, Dohi Taeko, Kannagi Reiji, "Colonic Epithelial Cells Express Specific Ligands for Mucosal Macrophage Immunosuppressive Receptors Siglec-7 and -9", The Journal of Immunology, Williams & Wilkins Co., US, US , (20120501), vol. 188, no. 9, doi:10.4049/jimmunol.1100605, ISSN 0022-1767, pages 4690 - 4700, XP055948833 | |
| OPPOSITION | - Zhang Meili, Ju Wei, Yao Zhengsheng, Yu Ping, Wei Bih-Rong, Simpson R. Mark, Waitz Rebecca, Fassò Marcella, Allison James P., Waldmann Thomas A., "Augmented IL-15Rα Expression by CD40 Activation Is Critical in Synergistic CD8 T Cell-Mediated Antitumor Activity of Anti-CD40 Antibody with IL-15 in TRAMP-C2 Tumors in Mice", The Journal of Immunology, Williams & Wilkins Co., US, US , (20120615), vol. 188, no. 12, doi:10.4049/jimmunol.1102604, ISSN 0022-1767, pages 6156 - 6164, XP055948840 | |
| OPPOSITION | - Laprevotte Emilie, Voisin Gregory, Ysebaert Loïc, Klein Christian, Daugrois Camille, Laurent Guy, Fournie Jean-Jacques, Quillet-Mary Anne, "Recombinant Human IL-15 Trans -Presentation by B Leukemic Cells from Chronic Lymphocytic Leukemia Induces Autologous NK Cell Proliferation Leading to Improved Anti-CD20 Immunotherapy", The Journal of Immunology, Williams & Wilkins Co., US, US , (20131001), vol. 191, no. 7, doi:10.4049/jimmunol.1300187, ISSN 0022-1767, pages 3634 - 3640, XP055943929 | |
| OTHER | - Carroll John, "Anti-PD-1? Well, no, says Medivation as a partial hold forces a halt to 'pivotal' cancer study", Fierce Biotech, (20160126), page 1, Fierce Biotech, URL: https://www.fiercebiotech.com/r-d/anti-pd-1-well-no-says-medivation-as-a-partial-hold-forces-a-halt-to-pivotal-cancer-study, XP093171494 | - |
| OTHER | - Lowe Derek, "Medivation Decides That Their Drug Isn't What They Thought", Science, AAAS, (20160126), pages 1 - 10, Science, AAAS, URL: https://www.science.org/content/blog-post/medivation-decides-their-drug-isn-t-they-thought, XP093171471 | - |
| OTHER | - Albuquerque Aline De, Da Silva Junior Haroldo Cid; Sartori Geraldo Rodrigues; Martins Da Silva João Hermínio, "Computationally-obtained structural insights into the molecular interactions between Pidilizumab and binding partners DLL1 and PD-1", JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, US , (20220922), vol. 40, no. 14, doi:10.1080/07391102.2021.1885492, ISSN 0739-1102, pages 6450 - 6462, XP093171502 | |
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