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Diagnosis Of Inflammatory Bowel Disease Based On Genes - EP3458466

The patent EP3458466 was granted to Cedars Sinai Medical Center on Aug 7, 2024. The application was originally filed on May 19, 2017 under application number EP17800279A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3458466

CEDARS SINAI MEDICAL CENTER
Application Number
EP17800279A
Filing Date
May 19, 2017
Status
Granted And Under Opposition
Jul 5, 2024
Grant Date
Aug 7, 2024
External Links
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Patent Oppositions (2)

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HAMPTON KNOWLESMay 6, 2025ADMISSIBLE
ZWICKER SCHNAPPAUF & PARTNERMay 6, 2025ADMISSIBLE

Patent Citations (20) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

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DESCRIPTIONUS5585089
INTERNATIONAL-SEARCH-REPORTUS2010240043
INTERNATIONAL-SEARCH-REPORTUS2012208900
INTERNATIONAL-SEARCH-REPORTUS2013136720
INTERNATIONAL-SEARCH-REPORTUS2015376707
INTERNATIONAL-SEARCH-REPORTWO2015138774
OPPOSITIONJP2004194534
OPPOSITIONUS2010240043
OPPOSITIONUS2012079611
OPPOSITIONUS2012208900
OPPOSITIONUS2015376707
OPPOSITIONWO2008106451
OPPOSITIONWO2010062960
OPPOSITIONWO2012161856
OPPOSITIONWO2014160883
OPPOSITIONWO2014186750
SEARCHWO2008106451
SEARCHWO2010062960
SEARCHWO2010075579
SEARCHWO2014186750

Non-Patent Literature (NPL) Citations (17) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
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OPPOSITION- Jostins Luke, "Using Next-Generation Genomic Datasets In Disease Association", Doctoral Dissertation, University of Cambridge, (20120901), XP093277819-
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OPPOSITION- Shih David Q, Xiaolan Zhang, Hon Wai Koon, Jyh-Yau Chang, Jeremy Chen, Brian L. Huang, Chenyang Li, Libo Zheng, Charalabos Pothoulakis, Stephan R. Targan, "357 Reversal of Murine Colitis and Fibrosis by Neutralizing TL1A Antibody: Potential Novel Therapy to Alter Natural History of Crohn's Disease", Gastroenterology (Author manuscript), W.B. Saunders, AMSTERDAM, NL, AMSTERDAM, NL, (20120501), vol. 142, no. 5, doi:10.1016/S0016-5085(12)60317-5, ISSN 0016-5085, pages S - S-84, XP093190877
OPPOSITION- Li Dalin; Haritunians Talin; Yan Xiaofei; McGovern Dermot, "324 Gene-Based Analysis Identified Multiple Novel IBD Loci", Gastroenterology, W.B. Saunders, AMSTERDAM, NL, AMSTERDAM, NL, (20160401), vol. 150, no. 4, doi:10.1016/S0016-5085(16)30370-5, ISSN 0016-5085, page S76, XP029511606
OPPOSITION- Cleynen Isabelle; Boucher Gabrielle; Jostins Luke; Schumm L Philip; Zeissig Sebastian; Ahmad Tariq; Andersen Vibeke; Andrews Jane M; Annese Vito; Brand Stephan; Brant Steven R; Cho Judy H; Daly Mark J; Dubinsky Marla; Duerr Richard H; Ferguson Lynnette R; Franke Andre; Gearry Richard B; Goyette Philippe; Hakonarson Hakon; Halfvarson Jonas; Hov Johannes R; Huang Hailang; Kennedy Nicholas A; Kupcinskas Limas; Lawrance Ian C; Lee James C; Satsangi Jack; Schreiber Stephan; Théâtre Emilie; van der Meulen-de Jong Andrea E; Weersma Rinse K; Wilson David C; Parkes Miles; Vermeire Severine; Rioux John D; Mansfield John; Silverberg Mark S; Radford-Smith Graham; McGovern Dermot P B; Barrett Jeffrey C; Lees Charlie W, "Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study", The Lancet, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20151018), vol. 387, no. 10014, doi:10.1016/S0140-6736(15)00465-1, pages 156 - 167, XP029382714
OPPOSITION- D Q Shih, L Zheng, X Zhang, H Zhang, Y Kanazawa, R Ichikawa, K L Wallace, J Chen, C Pothoulakis, H W Koon, S R Targan, "Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis", Mucosal Immunology, Nature Publishing Group US, New York, New York, (20141101), vol. 7, no. 6, doi:10.1038/mi.2014.37, ISSN 1933-0219, pages 1492 - 1503, XP055697841
OPPOSITION- Jeffrey C Barrett, Sarah Hansoul, Dan L Nicolae, Judy H Cho, Richard H Duerr, John D Rioux, Steven R Brant, Mark S Silverberg, Kent D Taylor, M Michael Barmada, Alain Bitton, Themistocles Dassopoulos, Lisa Wu Datta, Todd Green, Anne M Griffiths, Emily O Kistner, Michael T Murtha, Miguel D Regueiro, Jerome I Rotter, L Philip Schumm, A Hillary Steinhart, Stephan R Targan, Ramnik J Xavier, Cécile Libioulle, Cynthia Sandor, Mark Lathrop, Jacques Belaiche, Olivier Dewit, Ivo Gut, Simon Heath, Debby Laukens, Myriam Mni, Paul Rutgeerts, André Van Gossum, Diana Zelenika, Denis Franchimont, Jean-Pierre Hugot, Martine De Vos, Severine Vermeire, Edouard Louis, Lon R Cardon, Carl A Anderson, Hazel Drummond, Elaine Nimmo, Tariq Ahmad, Natalie J Prescott, Clive M Onnie, Sheila A Fisher, Jonathan Marchini, Jilur Ghori, Suzannah Bumpstead, Rhian Gwilliam, Mark Tremelling, Panos Deloukas, John Mansfield, Derek Jewell, Jack Satsangi, Christopher G Mathew, Miles Parkes, Michel Georges, Mark J Daly, "Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease", Nature Genetics, Nature America, Inc., (20080801), vol. 40, no. 8, doi:10.1038/ng.175, ISSN 10614036, pages 955 - 962, XP055033904
OPPOSITION- Van Limbergen Johan, Radford-Smith Graham, Satsangi Jack, "Advances in IBD genetics", Nature Reviews Gastroenterology, Nature Publishing Group UK, London, London, (20140601), vol. 11, no. 6, doi:10.1038/nrgastro.2014.27, ISSN 1759-5045, pages 372 - 385, XP093277834
OPPOSITION- Hidetoshi Takedatsu, Kathrin S. Michelsen, Bo Wei, Carol J. Landers, Lisa S. Thomas, Deepti Dhall, Jonathan Braun, Stephan R. Targan, "TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation.", Gastroenterology (Author manuscript), W.B. Saunders, AMSTERDAM, NL, AMSTERDAM, NL, (20080801), vol. 135, no. 2, doi:10.1053/j.gastro.2008.04.037, ISSN 0016-5085, pages 552 - 567, XP002668871
OPPOSITION- Alonso Arnald, Domènech Eugeni, Julià Antonio, Panés Julián, García-Sánchez Valle, Mateu Pilar Nos, Gutiérrez Ana, Gomollón Fernando, Mendoza Juan L., Garcia-Planella Esther, Barreiro-De Acosta Manuel, Muñoz Fernando, Vera Maribel, Saro Cristina, Esteve Maria, Andreu Montserrat, Chaparro Maria, Manyé Josep, Cabré Eduard, López-Lasanta María, Tortosa Raül, Gelpí Josep Lluís, García-Montero Andrés C., Bertranpetit Jaume, Absher Devin, Myers Richard M., Marsal Sara, Gisbert Javier P., "Identification of Risk Loci for Crohn’s Disease Phenotypes Using a Genome-Wide Association Study", Gastroenterology (Author manuscript), W.B. Saunders, AMSTERDAM, NL, AMSTERDAM, NL, (20150401), vol. 148, no. 4, doi:10.1053/j.gastro.2014.12.030, ISSN 0016-5085, pages 794 - 805, XP093277818
OPPOSITION- Raelson John V., Little Randall D., Ruether Andreas, Fournier Hélène, Paquin Bruno, Van Eerdewegh Paul, Bradley W. E. C., Croteau Pascal, Nguyen-Huu Quynh, Segal Jonathan, Debrus Sophie, Allard René, Rosenstiel Philip, Franke Andre, Jacobs Gunnar, Nikolaus Susanna, Vidal Jean-Michel, Szego Peter, Laplante Nathalie, Clark Hilary F., Paulussen René J., Hooper John W., Keith Tim P., Belouchi Abdelmajid, Schreiber Stefan, "Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci", Proceedings of the National Academy of Sciences (PNAS), National Academy of Sciences, (20070911), vol. 104, no. 37, doi:10.1073/pnas.0706645104, ISSN 0027-8424, pages 14747 - 14752, XP093277821
OPPOSITION- Byong Duk Ye, Mcgovern Dermot P. B., "Genetic variation in IBD: progress, clues to pathogenesis and possible clinical utility", EXPERT REVIEW OF CLINICAL IMMUNOLOGY, FUTURE DRUGS LTD., LONDON, GB, GB , (20160509), vol. 12, no. 10, doi:10.1080/1744666X.2016.1184972, ISSN 1744-666X, pages 1091 - 1107, XP055730782
OPPOSITION- Jacob Noam, Targan Stephan R, Shih David Q, "Cytokine and anti-cytokine therapies in prevention or treatment of fibrosis in IBD", United European Gastroenterol Journal, Sage, GB, GB , (20160801), vol. 4, no. 4, doi:10.1177/2050640616649356, ISSN 2050-6406, pages 531 - 540, XP093277825
OPPOSITION- Festen Eleonora A., Goyette Philippe, Green Todd, Boucher Gabrielle, Beauchamp Claudine, Trynka Gosia, Dubois Patrick C., Lagacé Caroline, Stokkers Pieter C. F., Hommes Daan W., Barisani Donatella, Palmieri Orazio, Annese Vito, Van Heel David A., Weersma Rinse K., Daly Mark J., Wijmenga Cisca, Rioux John D., "A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease", PLoS Genetics, Public Library of Science, US, US , vol. 7, no. 1, doi:10.1371/journal.pgen.1001283, ISSN 1553-7404, page e1001283, XP093277824
OPPOSITION- Kenny Eimear E., Pe'er Itsik, Karban Amir, Ozelius Laurie, Mitchell Adele A., Ng Sok Meng, Erazo Monica, Ostrer Harry, Abraham Clara, Abreu Maria T., Atzmon Gil, Barzilai Nir, Brant Steven R., Bressman Susan, Burns Edward R., Chowers Yehuda, Clark Lorraine N., Darvasi Ariel, Doheny Dana, Duerr Richard H., Eliakim Rami, Giladi Nir, Gregersen Peter K., Hakonarson Hakon, Jones Michelle R., Marder Karen, Mcgovern Dermot P. B., Mulle Jennifer, Orr-Urtreger Avi, Proctor Deborah D., Pulver Ann, Rotter Jerome I., Silverberg Mark S., Ullman Thomas, Warren Stephen T., Waterman Matti, Zhang Wei, Bergman Aviv, Mayer Lloyd, Katz Seymour, Desnick Robert J., Cho Judy H., Peter Inga, "A Genome-Wide Scan of Ashkenazi Jewish Crohn's Disease Suggests Novel Susceptibility Loci", PLoS Genetics, Public Library of Science, US, US , vol. 8, no. 3, doi:10.1371/journal.pgen.1002559, ISSN 1553-7404, page e1002559, XP093277823
OPPOSITION- Wallace Kori L, Li-Bo Zheng, Yoshitake Kanazawa, David Q Shih, "Immunopathology of inflammatory bowel disease", World Journal of Gastroenterology, WJG Press, CN, CN , (20140107), vol. 20, no. 1, doi:10.3748/wjg.v20.i1.6, ISSN 1007-9327, pages 6 - 21, XP093277831

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