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Systems And Methods To Detect Copy Number Variation - EP3470533

EP3470533

GUARDANT HEALTH
Application Number
EP18207391A
Filing Date
Sep 4, 2013
Status
Patent Maintained As Amended
Dec 16, 2022
Grant Date
Jan 18, 2023
External Links
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The patent EP3470533B2 was granted to Guardant Health on Jan 18, 2023 following the initial filing on Sep 4, 2013 under the application number EP18207391A . The current legal status of the patent is Patent Maintained As Amended.

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FOUNDATION MEDICINEAug 6, 2020WITHDRAWN

Patent Citations New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePatent NumberPatent Link
DESCRIPTIONUS2001053519
DESCRIPTIONUS2003152490
DESCRIPTIONUS2011160078
DESCRIPTIONUS6582908
DESCRIPTIONUS7537897
OPPOSITIONEP2893040
OPPOSITIONUS2012071331
OPPOSITIONUS2012165202
OPPOSITIONWO2012042374
OPPOSITIONWO2012129363
OPPOSITIONWO2012142213
OPPOSITIONWO2012148477
OPPOSITIONWO2013123442
OPPOSITIONWO2013138510
OPPOSITIONWO2013142389
SEARCHUS2012191367

Non-Patent Literature (NPL) Citations New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- A. J. Sehnert, B. Rhees, D. Comstock, E. De Feo, G. Heilek, J. Burke, R. P. Rava, "Optimal Detection of Fetal Chromosomal Abnormalities by Massively Parallel DNA Sequencing of Cell-Free Fetal DNA from Maternal Blood", Clinical Chemistry, P.B. Hoeber, (20110701), vol. 57, no. 7, pages 1042 - 1049-
OPPOSITION- Anonymous, "Interview with Professor Dennis Lo", Qiagen News, (20020101), no. 5, pages 2 - 3-
OPPOSITION- Anonymous, "Interview with Professor Dennis Lo", Qiagen News, (20020101), no. 5, pages 2 - 3, XP055646625-
OPPOSITION- CHIU et al., "Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma", PNAS, (20080000), vol. 105, pages 20458 - 20463-
OPPOSITION- Declaration of Professor Jay Shendure-
OPPOSITION- DIEHL et al., "Detection and quantification of mutations in the plasma of patients with colorectal tumors", PNAS, (20050000), vol. 102, no. 45, pages 16368 - 16373-
OPPOSITION- Diehl, F. et al, "Analysis of Mutations in DNA Isolated From Plasma and Stool of Colorectal Cancer Patients", Gastroenterology, Elsevier Inc., US, US, (20080801), vol. 135, no. 2, pages 489 - 498.e7-
OPPOSITION- EHRICH et al., "Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting", Am J Obsbet Gynecol., (20110000), vol. 204, no. 3, pages 205.e1 - 11-
OPPOSITION- Excerpt of expert report of Dr. Stacey Gabriel from US proceedings-
OPPOSITION- FAN et al., "Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood", PNAS, (20081021), vol. 105, no. 42, pages 16266 - 16271-
OPPOSITION- FLEISCHHACKER et al., "Circulating nucleic acids (CNAs) and cancer-A survey", Biochimica et Biophysica Acta, (20070000), vol. 1775, pages 181 - 232-
OPPOSITION- FORSHEW T, ET AL, "Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA.", Science Translational Medicine, American Association for the Advancement of Science (A A A S), US, US, (20120530), vol. 4, no. 136, pages 1 - 12-
OPPOSITION- Heidi Schwarzenbach, Dave S. B. Hoon, Klaus Pantel, "Cell-free nucleic acids as biomarkers in cancer patients", Nature Reviews Cancer, Nature Pub. Group, London, London, (20110601), vol. 11, no. 6, pages 426 - 437-
OPPOSITION- J. M. Rizzo, M. J. Buck, "Key Principles and Clinical Applications of "Next-Generation" DNA Sequencing", CANCER PREVENTION RESEARCH, American Association for Cancer Research, United States, United States, (20120701), vol. 5, no. 7, pages 887 - 900-
OPPOSITION- LEARY et al., "Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing", Science Translational Medicine, (20121100), vol. 4, no. 162, page 162ra154-
OPPOSITION- NARAYAN et al., "Ultrasensitive Measurement of Hotspot Mutations in Tumor DNA in Blood Using Error-Suppressed Multiplexed Deep Sequencing", Cancer Res, (20120510), vol. 72, no. 14, pages 3492 - 3498-
OPPOSITION- Perakis et. al. (2017) Advances in Clinical Chemistry pp.1-81-
OPPOSITION- SCHMITT et al., "Detection of ultra-rare mutations by next-generation sequencing", PNAS, (20120904), vol. 109, no. 36, pages 14508 - 14513-
OPPOSITION- Teemu Kivioja, Anna Vähärautio, Kasper Karlsson, Martin Bonke, Martin Enge, Sten Linnarsson, Jussi Taipale, "Counting absolute numbers of molecules using unique molecular identifiers.", NATURE METHODS, Nature Publishing Group, GB, GB, (20120101), vol. 9, no. 1, pages 72 - 74-
OPPOSITION- EHRICH et al., "Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting", Am J Obsbet Gynecol., (20110000), vol. 204, no. 3, doi:10.1016/j.ajog.2010.12.060, pages 205.e1 - 11, XP028184664
OPPOSITION- FLEISCHHACKER et al., "Circulating nucleic acids (CNAs) and cancer-A survey", Biochimica et Biophysica Acta, (20070000), vol. 1775, doi:10.1016/j.bbcan.2006.10.001, pages 181 - 232, XP002490780
OPPOSITION- Teemu Kivioja, Anna Vähärautio, Kasper Karlsson, Martin Bonke, Martin Enge, Sten Linnarsson, Jussi Taipale, "Counting absolute numbers of molecules using unique molecular identifiers.", NATURE METHODS, Nature Publishing Group, GB, GB, (20120101), vol. 9, no. 1, doi:10.1038/nmeth.1778, ISSN 1548-7105, pages 72 - 74, XP002729237
OPPOSITION- Heidi Schwarzenbach, Dave S. B. Hoon, Klaus Pantel, "Cell-free nucleic acids as biomarkers in cancer patients", Nature Reviews Cancer, Nature Pub. Group, London, London, (20110601), vol. 11, no. 6, doi:10.1038/nrc3066, ISSN 1474-175X, pages 426 - 437, XP055247315
OPPOSITION- Diehl, F. et al, "Analysis of Mutations in DNA Isolated From Plasma and Stool of Colorectal Cancer Patients", Gastroenterology, Elsevier Inc., US, US, (20080801), vol. 135, no. 2, doi:10.1053/j.gastro.2008.05.039, ISSN 0016-5085, pages 489 - 498.e7, XP023901355
OPPOSITION- DIEHL et al., "Detection and quantification of mutations in the plasma of patients with colorectal tumors", PNAS, (20050000), vol. 102, no. 45, doi:10.1073/pnas.0507904102, pages 16368 - 16373, XP002518285
OPPOSITION- FAN et al., "Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood", PNAS, (20081021), vol. 105, no. 42, doi:10.1073/pnas.0808319105, pages 16266 - 16271, XP055523982
OPPOSITION- CHIU et al., "Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma", PNAS, (20080000), vol. 105, doi:10.1073/pnas.0810641105, pages 20458 - 20463, XP002620454
OPPOSITION- SCHMITT et al., "Detection of ultra-rare mutations by next-generation sequencing", PNAS, (20120904), vol. 109, no. 36, doi:10.1073/pnas.1208715109, pages 14508 - 14513, XP055161683
OPPOSITION- FORSHEW T, ET AL, "Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA.", Science Translational Medicine, American Association for the Advancement of Science (A A A S), US, US, (20120530), vol. 4, no. 136, doi:10.1126/SCITRANSLMED.3003726, ISSN 1946-6234, pages 1 - 12, XP003030868
OPPOSITION- LEARY et al., "Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing", Science Translational Medicine, (20121100), vol. 4, no. 162, doi:10.1126/scitranslmed.3004742, page 162ra154, XP055565752
OPPOSITION- NARAYAN et al., "Ultrasensitive Measurement of Hotspot Mutations in Tumor DNA in Blood Using Error-Suppressed Multiplexed Deep Sequencing", Cancer Res, (20120510), vol. 72, no. 14, doi:10.1158/0008-5472.CAN-11-4037, pages 3492 - 3498, XP055407873
OPPOSITION- J. M. Rizzo, M. J. Buck, "Key Principles and Clinical Applications of "Next-Generation" DNA Sequencing", CANCER PREVENTION RESEARCH, American Association for Cancer Research, United States, United States, (20120701), vol. 5, no. 7, doi:10.1158/1940-6207.CAPR-11-0432, ISSN 1940-6207, pages 887 - 900, XP055486092
OPPOSITION- A. J. Sehnert, B. Rhees, D. Comstock, E. De Feo, G. Heilek, J. Burke, R. P. Rava, "Optimal Detection of Fetal Chromosomal Abnormalities by Massively Parallel DNA Sequencing of Cell-Free Fetal DNA from Maternal Blood", Clinical Chemistry, P.B. Hoeber, (20110701), vol. 57, no. 7, doi:10.1373/clinchem.2011.165910, ISSN 00099147, pages 1042 - 1049, XP055035087
SEARCH- LI HENG ET AL, "MAPPING SHORT DNA SEQUENCING READS AND CALLING VARIANTS USING MAPPING QUALITY SCORES", GENOME RESEARCH, COLD SPRING HARBOR LABORATORY PRESS, US, vol. 18, doi:10.1101/GR.078212.108, ISSN 1088-9051, (20080101), pages 1851 - 1858, (20080819), XP001503357 [A] 1-15 * the whole document *
SEARCH- J. A. SHAW ET AL, "Genomic analysis of circulating cell-free DNA infers breast cancer dormancy", GENOME RESEARCH, US, (20111011), vol. 22, no. 2, doi:10.1101/gr.123497.111, ISSN 1088-9051, pages 220 - 231, XP055223848 [A] 1-15 * abstract * * page 229, column l, paragraph l - page 230, column l, paragraph 2 *
SEARCH- B. DAINES ET AL, "High-Throughput Multiplex Sequencing to Discover Copy Number Variants in Drosophila", GENETICS, (20090615), vol. 182, no. 4, doi:10.1534/genetics.109.103218, ISSN 0016-6731, pages 935 - 941, XP055160491 [A] 1-15 * page 936, column l, paragraph 2 - paragraph 4 *

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