IP Verse

Plant Extract Highly Concentrated In Safranal, Production Method And Uses Thereof - EP3490575

The patent EP3490575 was granted to Activinside on Apr 16, 2025. The application was originally filed on Jul 28, 2017 under application number EP17754296A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP3490575

ACTIVINSIDE
Application Number
EP17754296A
Filing Date
Jul 28, 2017
Status
Patent Maintained As Amended
Mar 14, 2025
Publication Date
Apr 16, 2025
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

PHARMACTIVE BIOTECH PRODUCTSFeb 6, 2023PONSADMISSIBLE

Patent Citations (8) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
EXAMINATIONEP3446678
EXAMINATIONES2573542
INTERNATIONAL-SEARCH-REPORTFR2900053
INTERNATIONAL-SEARCH-REPORTFR2961379
INTERNATIONAL-SEARCH-REPORTFR2995185
OPPOSITIONES2573542
OPPOSITIONFR2900053
OPPOSITIONFR3017799

Non-Patent Literature (NPL) Citations (33) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
DESCRIPTION- HAUSENBLAS HA, "Saffron (Crocus sativus L.) and major depressive disorder: a metaanalysis of randomized clinical trials", Journal of integrative medicine, (20130000), vol. 11, no. 6, pages 377 - 83
DESCRIPTION- JAVADI B, "A survey on saffron in major islamic traditional medicine books", Iranian journal of basic médical sciences, (20130000), vol. 16, no. 1, pages 1 - 11
DESCRIPTION- AKHONDZADEH S, "Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial", BMC Complément Altern Med, (20040000), vol. 4, doi:doi:10.1186/1472-6882-4-12, page 12, XP021006396
EXAMINATION- Ramin Rezaee ET AL, "Safranal: From an Aromatic Natural Product to a Rewarding Pharmacological Agent Iranian Journal of Basic Medical Sciences", Iran J Basic Med Sci Iran J Basic M ed Sci, (20130112), pages 12 - 26, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637901/pdf/IJBMS-16-012.pdf, XP055666181
INTERNATIONAL-SEARCH-REPORT- Kulkarni, "Development of Extraction Methods and Quantification of Safranal by High Performance Liquid Chromatography from Cuminum cyminum L. and Studying its Antimicrobial Properties", International Proceedings of Chemical, Biological and Environmental Engineering, (20140101), URL: http://www.ipcbee.com/vol64/002-CEBCE2014-2-007.pdf, (20170310), XP055353603 [X] 1,2,6-10 * the whole document * * table 1 * [Y] 1-18
INTERNATIONAL-SEARCH-REPORT- L Ba ET AL, "Proprietary U-HPLC method IDENTIFIED MECHANISMS Pluri-parametric action Patented profile MORE THAN 25 COMPOUNDS SAFRANAL CROCIN DERIVATIVE COMPOUNDS SCIENCE Inside Proprietary Similar effects to Prozac", (20170501), URL: http://safrinside.com/wp-content/uploads/2017/05/brochure-safrinside3.pdf, (20170921), XP055408524 [XP] 1-18 * the whole document *
INTERNATIONAL-SEARCH-REPORT- Super Utilisateur, "saffron", (20160507), URL: http://web.archive.org/web/20160507080748/http://www.activinside.com/en/saffron, (20170310), XP055353526 [X] 1,2,5-10 * the whole document * [I] 1-18
INTERNATIONAL-SEARCH-REPORT- URBANI ELEONORA ET AL, "Investigation on secondary metabolite content and antioxidant activity of commercial saffron powder", EUROPEAN FOOD RESEARCH AND TECHNOLOGY, SPRINGER BERLIN HEIDELBERG, BERLIN/HEIDELBERG, vol. 242, no. 6, doi:10.1007/S00217-016-2687-Z, ISSN 1438-2377, (20160415), pages 987 - 993, (20160415), XP035868126 [X] 1,2,5-10 * the whole document * * table 2 * [Y] 1-18
INTERNATIONAL-SEARCH-REPORT- SUJATA V ET AL, "Methods for the analysis of the saffron metabolites crocin, crocetins, picrocrocin and safranal for the determination of the quality of the spice using thin-layer chromatography, high-performance liquid chromatography and gas chromatography", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER, AMSTERDAM, NL, vol. 624, no. 1-2, doi:10.1016/0021-9673(92)85699-T, ISSN 0021-9673, (19921030), pages 497 - 502, (19921030), XP026509354 [X] 1,2,5-10 * the whole document * * table III * [Y] 1-18
INTERNATIONAL-SEARCH-REPORT- LAGE M ET AL, "Quantification of saffron (Crocus sativus L.) metabolites crocins, picrocrocin and safranal for quality determination of the spice grown under different environmental Moroccan conditions", SCIENTIA HORTICULTURAE, ELSEVIER, AMSTERDAM, NL, vol. 121, no. 3, doi:10.1016/J.SCIENTA.2009.02.017, ISSN 0304-4238, (20090702), pages 366 - 373, (20090418), XP026096709 [X] 1,2,5-10 * the whole document * * table 4 * [Y] 1-18
INTERNATIONAL-SEARCH-REPORT- LOSKUTOV A V ET AL, "Development of an improved procedure for extraction and quantitation of safranal in stigmas of Crocus sativus L. using high performance liquid chromatography", FOOD CHEMISTRY, (200004), vol. 69, no. 1, ISSN 0308-8146, pages 87 - 95, XP009193692 [X] 1,2,5-10 * the whole document * * figure 1 * [Y] 1-18
INTERNATIONAL-SEARCH-REPORT- GRIFFITHS ET AL, "Editorial: Bladder Failure-A Condition to Reckon With", JOURNAL OF UROLOGY, LIPPINCOTT WILLIAMS & WILKINS, BALTIMORE, MD, US, (20030301), vol. 169, no. 3, doi:10.1097/01.JU.0000051323.18096.53, ISSN 0022-5347, pages 1011 - 1012, XP005535677 [Y] 1-18 * the whole document * * page 14; table 2 *
OPPOSITION- Akhondzadeh S, Et Al, "Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo-controlled trial", Phytotherapy Research, (20050101), vol. 19, pages 148 - 151, XP093028517
OPPOSITION- ALONSO, L. et al., Handbook of Herbs and Spices, (20120000), pages 1 - 617
OPPOSITION- Del Campo Priscila, Et Al, "Effects of mild temperature conditions during dehydration procedures on saffron quality parameters", J Sci Food Agric, (20100101), vol. 90, pages 719 - 725, XP093028511
OPPOSITION- Formisano Carmen, Et Al, "Volatile constituents of aerial parts of Centaurea sibthorpii (Sect. Carduiformes, Asteraceae) from Greece and their biological activity", Natural Product Research, (20080714), vol. 22, no. 10, pages 840 - 845, XP093028509
OPPOSITION- HIMENO H. et al., "Synthesis of Crocin, Picrocrocin and Safranal by Saffron Stigma-like Structures Proliferated in Vitro", Agric. Biol. Chem., (19870000), vol. 51, pages 2395 - 2400, XP001344664
OPPOSITION- KUHN R et al., "Synthese des safranals", Ber. Dtsch. Chem. Ges., (19360000), pages 1549 - 1555
OPPOSITION- Mohammadzadeh-Moghadam H, Et Al, "Effects of a Topical Saffron (Crocus sativus L) Gel on Erectile Dysfunction in Diabetics: A Randomized, Parallel-Group, Double-Blind, Placebo- Controlled Trial", J Evid Based Complementary Altern Med, (20150101), vol. 20, no. 4, pages 283 - 286, XP093028514
OPPOSITION- Rajabi Hamid, Et Al, "Retention of saffron bioactive components by spray drying encapsulation using maltodextrin, gum Arabic and gelatin as wall materials", Food Hydrocolloids, (20150101), vol. 51, pages 327 - 337, XP093028520
OPPOSITION- Sanchez Ana, Et Al, "Picrocrocin kinetics in aqueous saffron spice extracts (Crocus sativus L.) upon thermal treatment", J Agric Food Chem., (20110101), vol. 59, pages 249 - 255, XP093028521
OPPOSITION- HOSSEINZADEH H et al., "II Avicenna's (Ibn Sina) the Canon of Medicine and saffron (Crocus sativus): a review", Phytother Res., (20130000), vol. 27, no. 4, doi:10.1002/ptr.4784, pages 475 - 483, XP018507407
OPPOSITION- MODABBERNIA A et al., "Effect of saffron on fluoxetine-induced sexual impairment in men: randomized double-blind placebo-controlled trial", Psychopharmacology (Berl, (20120000), vol. 223, no. 4, doi:10.1007/s00213-012-2729-6, pages 381 - 388, XP035116802
OPPOSITION- PODRÍGUEZ-NEIRA, L. et al., "Influence of culinary processing time on saffron's bioactive compounds (Crocus sativus L.", Plant Foods Hum Nutr, (20140000), vol. 69, no. 4, doi:10.1007/s11130-014-0447-4, pages 291 - 296, XP035410947
OPPOSITION- WANG Y. et al., "Antidepressant properties of bioactive fractions from the extract of Crocus sativus L.", J Nat Med, (20100000), vol. 64, no. 1, doi:10.1007/s11418-009-0360-6, pages 24 - 30, XP055693554
OPPOSITION- RAHAIEE S et al., "Evaluation of antioxidant activitiesof bioactive compounds and varioused extracts obtained from saffron (Crocus sativus L.): a review", J Food Sci Technol, (20150000), vol. 52, pages 1881 - 1888, XP035475891
OPPOSITION- HOSSEINZADEH H et al., "Evaluation of the antitussive effect of stigma and petals of saffron (Crocus sativus) and its components, safranal and crocin in guinea pigs", Fitoterapia, (20060000), vol. 77, no. 6, doi:10.1016/j.fitote.2006.04.012, pages 446 - 448, XP024925862
OPPOSITION- SHAHMANSOURI N et al., "A randomized, double-blind, clinical trial comparing the efficacy and safety of Crocus sativus L. with fluoxetine for improving mild to moderate depression in post percutaneous coronary intervention patients", J Affect Disord, (20140000), vol. 155, doi:10.1016/j.jad.2013.11.003, pages 216 - 222, XP055394931
OPPOSITION- AKHONDZADEH S. et al., "Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression: a double-blind, randomized pilot trial", J Ethnopharmacol., (20050000), vol. 97, no. 2, doi:10.1016/j.jep.2004.11.004, pages 281 - 4, XP025269763
OPPOSITION- AKHONDZADEH S. et al., "Crocus sativus L. (petal) in the treatment of mild-to-moderate depression: a double-blind, randomized and placebo-controlled trial", Phytomedicine, (20060000), vol. 13, no. 9-10, doi:10.1016/j.phymed.2006.08.006, pages 607 - 611, XP028022182
OPPOSITION- SHAMSA A et al., "Evaluation of Crocus sativus L. (saffron) on male erectile dysfunction: a pilot study", Phytomedicine, (20090000), vol. 16, no. 8, doi:10.1016/j.phymed.2009.03.008, pages 690 - 693, XP026172688
OPPOSITION- FUKUI H et al., "Psychological and neuroendocrinological effects of odor of saffron (Crocussativus", Phytomedicine, (20110000), vol. 18, no. 8-9, doi:10.1016/j.phymed.2010.11.013, pages 726 - 730, XP028227271
OPPOSITION- AGHA-HOSSEINI M. et al., "S. Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo-controlled trial", BJOG, (20080300), vol. 115, no. 4, doi:10.1111/j.1471-0528.2007.01652.x, pages 515 - 519, XP002769579

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents