IP Verse

Methods And Systems For Detecting Genetic Variants - EP3524694

EP3524694

GUARDANT HEALTH
Application Number
EP19163403A
Filing Date
Dec 24, 2014
Status
Opposition Rejected
Jun 9, 2023
Grant Date
Jul 15, 2020
External Links
Slate, Register, Google Patents

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The patent EP3524694B1 was granted to Guardant Health on Jul 15, 2020 following the initial filing on Dec 24, 2014 under the application number EP19163403A . The current legal status of the patent is Opposition Rejected.

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Patent Oppositions (2)

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BUHLERApr 15, 2021ADMISSIBLE
FOUNDATION MEDICINEApr 15, 2021WITHDRAWN

Patent Citations New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePatent NumberPatent Link
DESCRIPTIONWO2013US58061-
DESCRIPTIONUS2001053519
DESCRIPTIONUS2003152490
DESCRIPTIONUS2011160078
DESCRIPTIONUS6582908
OPPOSITIONEP2893040
OPPOSITIONEP3378952
OPPOSITIONEP3524694
OPPOSITIONUS201361921456P
OPPOSITIONUS201461948509P
OPPOSITIONWO2012004237
OPPOSITIONWO2012038839
OPPOSITIONWO2012099832
OPPOSITIONWO2012142213
OPPOSITIONWO2013123442
OPPOSITIONWO2013142389
OPPOSITIONWO2014039556
OPPOSITIONWO2015100427
SEARCHWO2012038839
SEARCHWO2012054873
SEARCHWO2013123442
SEARCHWO2013142389
SEARCHWO2013181170
SEARCHWO2014039556

Non-Patent Literature (NPL) Citations New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- Anonymous, "Sample Preparation, NEBNext® DNA Library Prep Reagent Set for Illumina®", Instruction Manual, (20120600), pages 1 - 32, XP055964864-
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OPPOSITION- TIAN et al., "Structure-independent and quantitative ligation of single-stranded DNA", Analytical Biochemistry, (20060000), vol. 349, no. 2, pages 242 - 246, XP055964820-
OPPOSITION- EHRICH et al., "Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting", Am J Obstet Gynecol., (20110000), vol. 204, no. 3, doi:10.1016/j.ajog.2010.12.060, pages 205.e1 - 11, XP028184664
OPPOSITION- FLEISCHHACKER et al., "Circulating nucleic acids (CNAs) and cancer - A survey", Biochimica et Biophysica Acta, (20071007), vol. 1775, doi:10.1016/j.bbcan.2006.10.001, pages 181 - 232, XP002490780
OPPOSITION- Teemu Kivioja, Anna Vähärautio, Kasper Karlsson, Martin Bonke, Martin Enge, Sten Linnarsson, Jussi Taipale, "Counting absolute numbers of molecules using unique molecular identifiers.", NATURE METHODS, Nature Publishing Group, GB, GB , (20120101), vol. 9, no. 1, doi:10.1038/nmeth.1778 , ISSN 1548-7105, pages 72 - 74, XP002722751
OPPOSITION- Heidi Schwarzenbach, Dave S. B. Hoon, Klaus Pantel, "Cell-free nucleic acids as biomarkers in cancer patients", Nature Reviews Cancer, doi:10.1038/nrc3066, (20110000), pages 426 - 437, XP055247315
OPPOSITION- Emily Crowley, Federica Di Nicolantonio, Fotios Loupakis, Alberto Bardelli, "Liquid biopsy: monitoring cancer-genetics in the blood", NATURE REVIEWS CLINICAL ONCOLOGY, Nature, NY, US, NY, US , (20130801), vol. 10, no. 8, doi:10.1038/nrclinonc.2013.110, ISSN 1759-4774, pages 472 - 484, XP055494262
OPPOSITION- Diehl F; Schmidt K; Durkee K H; Moore K J; Goodman S N; Shuber A P; Kinzler K W; Vogelstein B, "Analysis of Mutations in DNA Isolated From Plasma and Stool of Colorectal Cancer Patients", Gastroenterology, (20080000), vol. 135, pages 489 - 498, XP023901355
OPPOSITION- DIEHL et al., "Detection and quantification of mutations in the plasma of patients with colorectal tumors", PNAS, (20050000), vol. 102, no. 45, doi:10.1073/pnas.0507904102, pages 16368 - 16373, XP002518285
OPPOSITION- FAN et al., "Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood", PNAS, (20081021), vol. 105, no. 42, doi:10.1073/pnas.0808319105, pages 16266 - 16271, XP055523982
OPPOSITION- CHIU et al., "Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma", PNAS, (20080000), vol. 105, no. 51, doi:10.1073/pnas.0810641105, pages 20458 - 20463, XP002620454
OPPOSITION- I. Kinde, J. Wu, N. Papadopoulos, K. W. Kinzler, B. Vogelstein, "Detection and quantification of rare mutations with massively parallel sequencing", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20110607), vol. 108, no. 23, doi:10.1073/pnas.1105422108, ISSN 0027-8424, pages 9530 - 9535, XP055732702
OPPOSITION- SCHMITT et al., "Detection of ultra-rare mutations by next-generation sequencing", PNAS, (20120904), vol. 109, no. 36, doi:10.1073/pnas.1208715109, pages 14508 - 14513, XP055161683
OPPOSITION- SCHMITT et al., "Detection of Ultra-rare mutations next-generation sequencing", PNAS, (20120904), vol. 109, no. 36, doi:10.1073/pnas.1208715109, pages 14508 - 14513, XP055161683
OPPOSITION- Greaves Laura C., Beadle Nina E., Taylor Geoffrey A., Commane Daniel, Mathers John C., Khrapko Konstantin, Turnbull Doug M., "Quantification of mitochondrial DNA mutation load", AGING CELL, BLACKWELL PUBLISHING,, GB, GB , (20091001), vol. 8, no. 5, doi:10.1111/j.1474-9726.2009.00505.x, ISSN 1474-9718, pages 566 - 572, XP055917856
OPPOSITION- FORSHEW et al., "Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA", Sci Transl Med, (20120530), vol. 4, no. issue 136, doi:10.1126/scitranslmed.3003726, page 136ra68, XP055450222
OPPOSITION- LEARY et al., "Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing", Science Translational Medicine, (20121100), vol. 4, no. issue 162, doi:10.1126/scitranslmed.3004742, page 162ra154, XP055565752
OPPOSITION- NARAYAN et al., "Ultrasensitive Measurement of Hotspot Mutations in Tumor DNA in Blood Using Error-Suppressed Multiplexed Deep Sequencing", Cancer Res, (20120510), vol. 72, no. 14, doi:10.1158/0008-5472.CAN-11-4037, pages 3492 - 3498, XP055407873
OPPOSITION- Rizzo J M; Buck M J, "Key Principles and Clinical Applications of ''Next- Generation'' DNA Sequencing", Cancer Prevention Research, doi: 10.1158/1940- 6207.CAPR-11 -0432, (20120500), pages 887 - 900, XP055486092
OPPOSITION- KENNEDY et al., "Ultra-Sensitive Sequencing Reveals an Age- Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage", PLOS Genetics, (20130926), vol. 9, no. issue 9, doi:10.1371/journal.pgen.1003794, pages 1 - 10, XP055529664
SEARCH- TEEMU KIVIOJA ET AL, "Counting absolute numbers of molecules using unique molecular identifiers", NATURE METHODS, (20111120), vol. 9, no. 1, doi:10.1038/nmeth.1778, ISSN 1548-7091, pages 72 - 74, XP055201576 [A] 1-15 * the whole document *
SEARCH[ ] - TEEMU KIVIOJA ET AL, "Counting absolute numbers of molecules using unique molecular identifiers. Supplementary information.", NATURE METHODS, (20111120), vol. 9, no. 1, doi:10.1038/nmeth.1778, ISSN 1548-7091, pages 72 - 74, XP055201583 [ ] * the whole document *
SEARCH- SCOTT R KENNEDY ET AL, "Detecting ultralow-frequency mutations by Duplex Sequencing", NATURE PROTOCOLS, GB, (20141009), vol. 9, no. 11, doi:10.1038/nprot.2014.170, ISSN 1754-2189, pages 2586 - 2606, XP055390095 [T] * the whole document *
SEARCH- G. K. FU ET AL, "Counting individual DNA molecules by the stochastic attachment of diverse labels", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20110531), vol. 108, no. 22, doi:10.1073/pnas.1017621108, ISSN 0027-8424, pages 9026 - 9031, XP055164127 [A] 1-15 * the whole document *
SEARCH- M. W. SCHMITT ET AL, "Detection of ultra-rare mutations by next-generation sequencing", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20120801), vol. 109, no. 36, doi:10.1073/pnas.1208715109, ISSN 0027-8424, pages 14508 - 14513, XP055161683 [A] 1-15 * the whole document *
SEARCH- SCOTT R. KENNEDY ET AL, "Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage", PLOS GENETICS, (20130926), vol. 9, no. 9, doi:10.1371/journal.pgen.1003794, pages 1 - 10, XP055529664 [A] 1-15 * the whole document *

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