The patent EP3525781 was granted to Fresenius Kabi Deutschland on Apr 24, 2024. The application was originally filed on Oct 5, 2017 under application number EP17780718A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
Patent citations refer to prior patents cited during different phases such as opposition or international search.
| Citation Phase | Publication Number |
|---|---|
| DESCRIPTION | US2003068385 |
| DESCRIPTION | US6750048 |
| DESCRIPTION | WO0176385 |
| DESCRIPTION | WO0176715 |
| DESCRIPTION | WO2012028543 |
| INTERNATIONAL-SEARCH-REPORT | US2003068385 |
| INTERNATIONAL-SEARCH-REPORT | WO2012028543 |
| OPPOSITION | WO2007075841 |
| OPPOSITION | WO2012033538 |
| OPPOSITION | WO2015113986 |
NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.
| Citation Phase | Reference Text |
|---|---|
| INTERNATIONAL-SEARCH-REPORT | - AGNIHOTRI N ET AL, "Fish oil increases the chemotherapeutic efficacy of 5-Fluorouracil by altering the membrane characteristics and drug uptake", EUROPEAN JOURNAL OF CANCER, & EUROPEAN CANCER CONGRESS 2015 / 18TH MEETING OF THE EUROPEAN-CANCER-ORGANIZATION (ECCO) / 40TH MEETI; VIENNA, AUSTRIA; SEPTEMBER 25 -29, 2015, (201509), vol. 51, no. Suppl. 3, page S385, XP002767899 [A] 1-13 * abstract * |
| INTERNATIONAL-SEARCH-REPORT | - SALA-VILA A ET AL, "The effect of three lipid emulsions differing in fatty acid composition on growth, apoptosis and cell cycle arrest in the HT-29 colorectal cancer cell line", CLINICAL NUTRITION, CHURCHILL LIVINGSTONE, LONDON, GB, vol. 29, no. 4, ISSN 0261-5614, (20100801), pages 519 - 524, (20091128), XP027178516 [A] 1-13 * table 1 * * page 519, abstract * |
| INTERNATIONAL-SEARCH-REPORT | - YANG TING ET AL, "N-3 PUFAs have antiproliferative and apoptotic effects on human colorectal cancer stem-like cells in vitro", THE JOURNAL OF NUTRITIONAL BIOCHEMISTRY, ELSEVIER, AMSTERDAM, NL, (20120731), vol. 24, no. 5, doi:10.1016/J.JNUTBIO.2012.03.023, ISSN 0955-2863, pages 744 - 753, XP028586045 [A] 1-13 * page 749, column r, paragraph 4. * * page 753, left-hand column, last paragraph * |
| INTERNATIONAL-SEARCH-REPORT | - GRANCI VIRGINIE ET AL, "Colon cancer cell chemosensitisation by fish oil emulsion involves apoptotic mitochondria pathway", BRITISH JOURNAL OF NUTRITION, (201304), vol. 109, no. 7, pages 1188 - 1195, XP002767900 [A] 1-13 * page 1188, abstract * |
| OPPOSITION | - "4.4.1.1 Eicosapentaenoic Acid", NAGI B. KUMAR, Nutritional Management of cancer Treatment Effects, Berlin / Heidelberg, Springer, (20180218), pages 70 - 71, XP055861217 |
| OPPOSITION | - Anonymous, "Fish Oil", Chemical Book, (2017), URL: https://www.chemicalbook.com/ChemicalProductProperty_EN_CB5128501.htm, XP055861210 |
| OPPOSITION | - GAVHANE Y. N. et al., "Solid Tumors: Facts, Challenges and Solutions", International Journal of Pharma Sciences and Research (IJPSR), (20110100), vol. 2, no. 1, pages 1 - 12, XP055861195 |
| OPPOSITION | - MORLAND et al., "n-3 polyunsaturated fatty acid supplementation during cancerchemotherapy", Journal of Nutrition & Intermediary Metabolism, (20160527), vol. 5, pages 10 - 116 |
| OPPOSITION | - Rachel A. Murphy; Marina Mourtzakis; Quincy S. C. Chu; Vickie E. Baracos; Tony Reiman; Vera C. Mazurak, "Supplementation with fish oil increases first‐line chemotherapy efficacy in patients with advanced nonsmall cell lung cancer", Cancer, American cancer society , Philadelphia , PA, US, US , (20110215), vol. 117, no. 16, doi:10.1002/cncr.25933, ISSN 0008-543X, pages 3774 - 3780 |
| OPPOSITION | - Rachel A. Murphy; Marina Mourtzakis; Quincy S. C. Chu; Vickie E. Baracos; Tony Reiman; Vera C. Mazurak, "Supplementation with fish oil increases first‐line chemotherapy efficacy in patients with advanced nonsmall cell lung cancer", Cancer, American cancer society , Philadelphia , PA, US, US , (20110215), vol. 117, no. 16, doi:10.1002/cncr.25933, ISSN 0008-543X, pages 3774 - 3780, XP071039079 |
| OPPOSITION | - MORLAND et al., "n-3 polyunsaturated fatty acid supplementation during cancerchemotherapy", Journal of Nutrition & Intermediary Metabolism, (20160527), vol. 5, pages 10 - 116, XP055861198 |
| OPPOSITION | - G Ramesh, U.N Das, "Effect of cis-unsaturated fatty acids on Meth-A ascitic tumour cells in vitro and in vivo", CANCER LETTERS, NEW YORK, NY, US, US , (19980101), vol. 123, no. 2, doi:10.1016/S0304-3835(97)00426-6, ISSN 0304-3835, pages 207 - 214, XP055302906 |
| OPPOSITION | - D'ELISEO et al., "Omega-3 Fatty Acids and Cancer Cell Cytotoxicity: Implications for Multi-Targeted Cancer Therapy", Journal of Clinical Medicine, (20160126), vol. 5, no. 2, page 15, XP055861204 |
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