Use Of Tonicifying Agents To Enhance Recombinant Adeno-Associated Virus Yield - EP3526321

The patent EP3526321 was granted to Dimension Therapeutics on Nov 27, 2024. The application was originally filed on Oct 13, 2017 under application number EP17859455A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3526321

DIMENSION THERAPEUTICS
Application Number
EP17859455A
Filing Date
Oct 13, 2017
Status
Granted And Under Opposition
Oct 25, 2024
Grant Date
Nov 27, 2024
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

STRAWMANAug 27, 2025HOFFMANN EITLEADMISSIBLE

Patent Citations (19) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS2002081721
DESCRIPTIONUS2015353899
DESCRIPTIONUS5387484
DESCRIPTIONUS5688676
DESCRIPTIONUS5691176
DESCRIPTIONUS5741683
DESCRIPTIONUS6156303
DESCRIPTIONUS8163543
DESCRIPTIONWO0024916
DESCRIPTIONWO0047757
DESCRIPTIONWO9617947
INTERNATIONAL-SEARCH-REPORTUS2004235173
INTERNATIONAL-SEARCH-REPORTUS2005148076
INTERNATIONAL-SEARCH-REPORTUS5872005
OPPOSITIONUS6566118
OPPOSITIONWO9617947
SEARCHUS6566118
SEARCHWO0014205
SEARCHWO2012122625

Non-Patent Literature (NPL) Citations (27) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- CLARK et al., Human Gene Therapy, (19950000), vol. 6, pages 1329 - 1341-
DESCRIPTION- CLARK et al., Hum. Gene Ther., (19990000), vol. 10, pages 1031 - 1039-
DESCRIPTION- FRASER WRIGHT, Human Gene Therapy, (20090000), vol. 20, pages 807 - 817-
DESCRIPTION- GAO et al., J. Virol., (20040000), vol. 78, no. 12, pages 6381 - 6388-
DESCRIPTION- HERMONAT et al., Molecular Therapy, (20040000), vol. 9, pages S289 - S290-
DESCRIPTION- LOCK et al., Human Gene Therapy Methods, (20140000), vol. 25, no. 2, pages 115 - 125-
DESCRIPTION- MARTIN et al., Human Gene Therapy Methods, (20130000), vol. 24, pages 253 - 269-
DESCRIPTION- SAMULSKI et al., J. Virol., (19890000), vol. 63, pages 3822 - 3828-
DESCRIPTION- SOMMER et al., Mol. Ther., (20030000), vol. 7, pages 122 - 128-
DESCRIPTION- SRIVASTAVA, J. Cell Biochem., (20080000), vol. 105, no. 1, pages 17 - 24-
DESCRIPTION- STROBEL et al., Human Gene Therapy Methods, (20150000), vol. 26, no. 4, pages 147 - 157-
DESCRIPTION- WANG et al., Mol Ther Methods Clin Dev., (20150000), vol. 2, page 15040-
DESCRIPTION- WEINBAUER et al., Limnology and Oceanography, (20090000), vol. 54, no. 3, pages 774 - 784-
DESCRIPTION- WEITZMAN et al., Adeno-associated virus biology. Adeno-Associated Virus: Methods and Protocols, (20110000), pages 1 - 23-
DESCRIPTION- WILLIAMS, J. Gen. Virol., (19700000), vol. 9, no. 3, pages 251 - 5-
DESCRIPTION- YANG et al., Hepatology, (20080000), vol. 48, no. 5, pages 1396 - 403-
DESCRIPTION- ZHEN et al., Human Gene Therapy, (20040000), vol. 15, pages 709 - 715-
OPPOSITION- Alfredo Criollo ; Lorenzo Galluzzi ; M. Chiara Maiuri ; Ezgi Tasdemir ; Sergio Lavandero ; Guido Kroemer, "Mitochondrial control of cell death induced by hyperosmotic stress", Apoptosis ; An International Journal on Programmed Cell Death, Bo , (20061031), vol. 12, no. 1, ISSN 1573-675X, pages 3 - 18, XP019463717-
OPPOSITION- Anonymous , "EX-CELL HeLa Serum-Free Medium for HeLa Cells without L-glutamine", SAFC Biosciences, (20060101), pages 1 - 2, XP093310409-
OPPOSITION- CLARK K. R., VOULGAROPOULOU F., JOHNSON P. R., "A stable cell line carrying adenovirus-induciblr rep and cap genes allows for infectivity titration of adeno-associated virus vectors", Gene Therapy, GB , (19960101), vol. 3, ISSN 0969-7128, pages 1124 - 1132., XP002064828-
OPPOSITION- D6 - “Certificate of Analysis” for DMEM/high glucose (Lonza/BioWhittaker)-
OPPOSITION- D7a - “Certificate of Analysis” for EX-CELL HeLa serum-free media-
OPPOSITION- Chun Fang Shen; Robert Voyer; Roseanne Tom; Amine Kamen, "Reassessing culture media and critical metabolites that affect adenovirus production", Biotechnology Progress, Hoboken, USA, (20090902), vol. 26, no. 1, doi:10.1002/btpr.286, ISSN 8756-7938, pages 200 - 207, XP072297114
OPPOSITION- Nathalie Clement, Joshua C Grieger, "Manufacturing of recombinant adeno-associated viral vectors for clinical trials", Molecular therapy- methods & clinical development, GB , (20160101), vol. 3, doi:10.1038/mtm.2016.2, ISSN 2329-0501, pages 1 - 7, XP055387003
OPPOSITION- John Martin, Amy Frederick, Yuxia Luo, Robert Jackson, Michelle Joubert, Bruce Sol, Francis Poulin, Eric Pastor, Donna Armentano, Samuel Wadsworth, Karen Vincent, "Generation and Characterization of Adeno-Associated Virus Producer Cell Lines for Research and Preclinical Vector Production", Human Gene Therapy, US , (20130801), vol. 24, no. 4, doi:10.1089/hgtb.2013.046, ISSN 1946-6536, pages 253 - 269, XP055312388
OPPOSITION- Vandenberghe Luk H., Xiao Ru, Lock Martin, Lin Jianping, Korn Michael, Wilson James M., "Efficient Serotype-Dependent Release of Functional Vector into the Culture Medium During Adeno-Associated Virus Manufacturing", Humae Gene Therapy, GB , (20101001), vol. 21, no. 10, doi:10.1089/hum.2010.107, ISSN 1043-0342, pages 1251 - 1257, XP055925396
OPPOSITION- Gouffi Kamila, Pichereau Vianney, Rolland Jean-Paul, Thomas Daniel, Bernard Théophile, Blanco Carlos, "Sucrose Is a Nonaccumulated Osmoprotectant in Sinorhizobium meliloti", Journal of Bacteriology, US , (19981001), vol. 180, no. 19, doi:10.1128/JB.180.19.5044-5051.1998, ISSN 0021-9193, pages 5044 - 5051, XP093310417

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents