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OPPOSITION | - Anonymous, "These Companies Are Racing To Develop The Next Big Cholesterol Drug", Business Insider, (20110831), pages 1 - 6, Business Insider, URL: https://www.businessinsider.com/hearty-profits-companies-racing-to-develop-the-next-big-cholesterol-drug-2011-8, (20240529), XP093168316 | - |
OPPOSITION | - D91 - EXCERPT FROM AMGEN'S DEFENCE RE RULE 109 REQUEST | - |
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OPPOSITION | - Gary Swergold, "REGN727/SAR236553, a Fully-Human Monoclonal Antibody to Proprotein Convertase Subtilisin Kexin 9 (PCSK9), Decreases ApoB and Non-HDL-C When Administered Intravenously to Healthy Volunteer", Journal of clinical lipidology, (20110601), vol. 5, no. 3, pages 219 - 219, XP093168326 | - |
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OPPOSITION | - Swergold Gary, Stephanie Biedermann, Rumiana Renard, Doug Nadler, Richard Wu, Eleanor A. Lisbon, Maria J. Gutierrez, Scott Mellis, "REGN727/SAR236553, a Fully-Human Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Monoclonal Antibody: Effects on Safety and Lipid and Lipoprotein Profiles When Administered Subcutaneously", American College of Cardiology annual scientific session & expo 2011; April 3-5, 2011, American College of Cardiology, (20110403), pages 1 - 1, XP093262425 | - |
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OPPOSITION | - Evan A. Stein, Scott Mellis, George D. Yancopoulos, Neil Stahl, Douglas Logan, William B. Smith, Eleanor Lisbon, Maria Gutierrez, Cheryle Webb, Richard Wu, Yunling Du, Therese Kranz, Evelyn Gasparino, Gary D. Swergold, "Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol", New England Journal of Medicine, (20120322), vol. 366, no. 12, doi:10.1056/NEJMoa1105803, ISSN 00284793, pages 1108 - 1118, XP055049842 | |
OPPOSITION | - Marc S. Sabatine, Robert P. Giugliano, Anthony C. Keech, Narimon Honarpour, Stephen D. Wiviott, Sabina A. Murphy, Julia F. Kuder, Huei Wang, Thomas Liu, Scott M. Wasserman, Peter S. Sever, Terje R. Pedersen, "Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease", The New England journal of medicine, Massachusetts Medical Society, US, US , (20170504), vol. 376, no. 18, doi:10.1056/NEJMoa1615664, ISSN 0028-4793, pages 1713 - 1722, XP055474155 | |
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