IP Verse

Non-Unique Barcodes In A Genotyping Assay - EP3541951

The patent EP3541951 was granted to Personal Genome Diagnostics on Nov 20, 2024. The application was originally filed on Nov 14, 2017 under application number EP17872140A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3541951

PERSONAL GENOME DIAGNOSTICS
Application Number
EP17872140A
Filing Date
Nov 14, 2017
Status
Granted And Under Opposition
Oct 18, 2024
Grant Date
Nov 20, 2024
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateOpposition Status

Get instant alerts for new oppositions and patent status changes

STRAWMANAug 20, 2025ADMISSIBLE

Patent Citations (43) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS2002190663
DESCRIPTIONUS2006024681
DESCRIPTIONUS2006292611
DESCRIPTIONUS2007114362
DESCRIPTIONUS2008081330
DESCRIPTIONUS2009026082
DESCRIPTIONUS2009318310
DESCRIPTIONUS2010285578
DESCRIPTIONUS2010300559
DESCRIPTIONUS2010300895
DESCRIPTIONUS2010301398
DESCRIPTIONUS2010304982
DESCRIPTIONUS2011009278
DESCRIPTIONUS2011257889
DESCRIPTIONUS2011301042
DESCRIPTIONUS2014065621
DESCRIPTIONUS2016046986
DESCRIPTIONUS5234809
DESCRIPTIONUS5583024
DESCRIPTIONUS5674713
DESCRIPTIONUS5700673
DESCRIPTIONUS6210891
DESCRIPTIONUS6223128
DESCRIPTIONUS6235475
DESCRIPTIONUS6306597
DESCRIPTIONUS6828100
DESCRIPTIONUS6833246
DESCRIPTIONUS6911345
DESCRIPTIONUS7232656
DESCRIPTIONUS7598035
DESCRIPTIONUS7666593
DESCRIPTIONUS7776616
DESCRIPTIONUS7809509
DESCRIPTIONUS7835871
DESCRIPTIONUS7957913
DESCRIPTIONUS7960120
DESCRIPTIONUS8165821
INTERNATIONAL-SEARCH-REPORTUS2014066317
INTERNATIONAL-SEARCH-REPORTUS2016273049
OPPOSITIONUS2014065621
OPPOSITIONWO2014039556
OPPOSITIONWO2014149134
SEARCHUS2014065621

Non-Patent Literature (NPL) Citations (16) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- KLEIN et al., "LOCAS-A low coverage sequence assembly tool for re-sequencing projects", PLoS One, (20110000), vol. 6, no. 8, page 23455-
DESCRIPTION- MARGULIES, M. et al., "Genome sequencing in micro-fabricated high-density picotiter reactors", Nature, (20050000), vol. I-IV, pages 376 - 380-
DESCRIPTION- SAMBROOK, J et al., Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, (20010000), vol. 1-3, page 2,028-
DESCRIPTION- XUE et al., "Optimizing the Yield and Utility of Circulating Cell-Free DNA from Plasma and Serum", Clin. Chim. Acta., (20090000), vol. 404, no. 2, doi:10.1016/j.cca.2009.02.018, pages 100 - 104, XP055536157
DESCRIPTION- ROTHBERG et al., "An integrated semiconductor device enabling non-optical genome sequencing", Nature, (20110000), vol. 475, doi:10.1038/nature10242, pages 348 - 352, XP055268437
DESCRIPTION- NEWMAN et al., "Integrated digital error suppression for improved detection of circulating tumor DNA", Nat. Bio., (20160000), vol. 34, no. 5, doi:10.1038/nbt.3520, XP055802486
DESCRIPTION- LI et al., "Whole Genome Amplification of Plasma-Circulating DNA Enables Expanded Screening for Allelic Imbalance in Plasma", J. Mol Diagn., (20060200), vol. 8, no. 1, doi:10.2353/jmoldx.2006.050074, pages 22 - 30, XP055149339
INTERNATIONAL-SEARCH-REPORT- NEWMAN, ARON M et al., "Integrated digital error suppression for improved detection of circulating tumor DNA", Nature Biotechnology, (20160500), vol. 34, no. 5, pages 547 - 555, XP055464348 [A] 1-23 * See pages 547, 549, 551; and online methods. *
INTERNATIONAL-SEARCH-REPORT- KINDE, ISAAC et al., "Detection and quantification of rare mutations with massively parallel sequencing", Proceedings of the National Academy of Science, U.S.A., (20110607), vol. 108, no. 23, pages 9530 - 9535, XP055164202 [X] 1-23 * See pages 9530-9533, 9535; and figures 1-2. *
INTERNATIONAL-SEARCH-REPORT- PENG, QUAN et al., "Reducing amplification artifacts in high multiplex amplicon sequencing by using molecular barcodes", BMC Genomics, (20150807), vol. 16, pages 1 - 12, XP021224943 [A] 1-23 * See pages 2-3, 9-11. *
OPPOSITION- Anonymous, "PLASMASELECT-R™", Product Information, PGD - Personal Genome Diagnostics, (20150527), pages 1 - 2, Product Information, URL: https://web.archive.org/web/20160704233420/http://www.personalgenome.com/wp-content/uploads/2015/05/PGDx_PlasmaSelect-R_Product_Information.pdf, XP093309053-
OPPOSITION- Aaron M Newman, Alexander F Lovejoy, Daniel M Klass, David M Kurtz, Jacob J Chabon, Florian Scherer, Henning Stehr, Chih Long Liu, Scott V Bratman, Carmen Say, Li Zhou, Justin N Carter, Robert B West, George W Sledge Jr, Joseph B Shrager, Billy W Loo, Joel W Neal, Heather A Wakelee, Maximilian Diehn, Ash A Alizadeh, "Integrated digital error suppression for improved detection of circulating tumor DNA", Nature Biotechnology, Nature Publishing Group US, New York, New York, (20160501), vol. 34, no. 5, doi:10.1038/nbt.3520, ISSN 1087-0156, pages 547 - 555, XP055464348
OPPOSITION- Mardis Elaine R, "DNA sequencing technologies: 2006-2016", Nature Protocols, Nature Publishing Group, GB, GB , (20170105), vol. 12, no. 2, doi:10.1038/nprot.2016.182, ISSN 1754-2189, pages 213 - 218, XP037547624
OPPOSITION- Kinde I., Wu J., Papadopoulos N., Kinzler K. W., Vogelstein B., "Supporting Information: Detection and quantification of rare mutations with massively parallel sequencing", Proceedings of the National Academy of Sciences (PNAS), National Academy of Sciences, (20110607), vol. 108, no. 23, doi:10.1073/pnas.1105422108, ISSN 0027-8424, pages 9530 - 9535, XP055815700
SEARCH- AARON M NEWMAN ET AL, "Integrated digital error suppression for improved detection of circulating tumor DNA", NATURE BIOTECHNOLOGY, us, (20160328), vol. 34, no. 5, doi:10.1038/nbt.3520, ISSN 1087-0156, pages 547 - 555, XP055464348 [X] 1-7 * page 548, column 1; supplemental material; figure 1; Table 4 *
SEARCH- I. KINDE ET AL, "Detection and quantification of rare mutations with massively parallel sequencing", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20110517), vol. 108, no. 23, doi:10.1073/pnas.1105422108, ISSN 0027-8424, pages 9530 - 9535, XP055164202 [Y] 1-7 * figures *

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents