IP Verse

Ribonucleic Acid Purification - EP3578652

The patent EP3578652 was granted to Moderna on Jul 12, 2023. The application was originally filed on Mar 13, 2014 under application number EP18208038A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3578652

MODERNA
Application Number
EP18208038A
Filing Date
Mar 13, 2014
Status
Granted And Under Opposition
Jun 9, 2023
Grant Date
Jul 12, 2023
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

CYTIVA SWEDENApr 11, 2024MAIWALDADMISSIBLE

Patent Citations (6) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
OPPOSITIONWO9006045
OTHERUS4654267
OTHERUS5512439
OTHERWO8303920
SEARCHWO2004020575
SEARCHWO9303052

Non-Patent Literature (NPL) Citations (24) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- A.L. LEHNINGER, Biochemistry, Worth Publishers, Inc.-
DESCRIPTION- CAREY; SUNDBERG, Advanced Organic Chemistry, Plenum Press, (19920000), vol. A, B-
DESCRIPTION- Methods In Enzymology, Academic Press, Inc.-
OPPOSITION- Anonymous, "Overview of Affinity Purification", Thermo Fischer, (20160101), pages 1 - 7, XP093219051-
OPPOSITION- Anonymous, "Product Description of Oligo (dT)-Cellulose columns.", Molecular Research center, (20000101), pages 1 - 2, Molecular Research center, URL: https://search.cosmobio.co.jp/cosmo_search_p/search_gate2/docs/MOR_/OT125.20020418.pdf, XP093219053-
OPPOSITION- Bangs Laboratories, Inc., "BioMag® Oligo dT(20), Nuclease-free", Product Data Sheet 529, (20130307), XP093185912-
OPPOSITION- Bio-Rad Laboratories, Inc., "Profinity™ Epoxide Resin ", Instruction Manual, (20050101), page 12pp, XP093185921-
OPPOSITION- Clontech Laboratories, Inc., "UniLink™ AminoModifier", User Manual, (20030506), pages 1 - 11, XP093185928-
OPPOSITION- Devor Eric J, Behlke Mark A, "Strategies for Attaching Oligonucleotides to Solid Supports", IDT® Paper, (20080101), pages 1 - 24, XP093185926-
OPPOSITION- Hermanson Greg T., Mallia A. Krishna, Smith Paul K., Immobilized Affinity Ligand Techniques, Academic Press, Inc., (19920101), pages 85 - 87, 255, 256, 268 - 270, XP093185910-
OPPOSITION- Polysciences, Inc., "BioMag® SelectaPure mRNA Purification System", Technical Data Sheet 569, (20110325), pages 1 - 5, XP093185914-
OPPOSITION- Robert J. Slater, "The Purification of Poly(A)- Containing RNA by Affinity Chromatography", Methods Mol. Biol, (19840101), vol. 2, pages 117 - 120, XP001314843-
OPPOSITION- BERENSMEIER SONJA, "Magnetic particles for the separation and purification of nucleic acids.", Applied Microbiology and Biotechnology, Springer Berlin Heidelberg, Berlin/Heidelberg, Berlin/Heidelberg, (20061201), vol. 73, no. 3, doi:10.1007/s00253-006-0675-0, ISSN 0175-7598, pages 495 - 504, XP002440338
OPPOSITION- Jeffrey B. Wheatley et al., "Salt-induced immobilization of affinity ligands onto epoxide-activated supports", Journal of Chromatography A, (1999), vol. 849, doi:10.1016/S0021-9673(99)00484-7, XP004173674
OPPOSITION- J.P. Cloarec et al., "Immobilization of homooligonucleotide probe layers onto Si/SiO2 substrates: characterization by electrochemical impedance measurements and radiobelling", Biosensors & Bioelectronics, (2002), vol. 17, doi:10.1016/S0956-5663(01)00282-2, XP002295901
OPPOSITION- JACOBSEN N, ET AL., "DIRECT ISOLATION OF POLY(A)+ RNA FROM 4 M GUANIDINE THIOCYANATE-LYSED CELL EXTRACTS USING LOCKED NUCLEIC ACID-OLIG(T) CAPTURE", Nucleic Acids Research, Oxford University Press, GB, GB , (20040101), vol. 32, no. 07, doi:10.1093/nar/gnh056, ISSN 0305-1048, pages E64/01 - E64/10, XP008049672
SEARCH- HAMAGUCHI Y ET AL, "Direct reverse transcription-PCR on oligo(dT)-immobilized polypropylene microplates after capturing total mRNA from crude cell lysates", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, (19980101), vol. 44, no. 11, ISSN 0009-9147, pages 2256 - 2263, XP002208861 [A] 1-15 * the whole document *-
SEARCH- JAKOBSEN K S ET AL, Direct mRNA Isolation Using Magnetic Oligo (dT) Beads: A Protocol for All Types of Cell Cultures, Animal and Plant Tissues, ADVANCES IN BIOMAGNETIC SEPARATION, EATON PUBLISHING, NATICK, MA, US, PAGE(S) I-V, (19940601), ISBN 978-1-881299-01-1, XP003032616 [A] 1-15 * the whole document *-
SEARCH- SASAKI Y F ET AL, "CONSTRUCTION OF A NORMALIZED CDNA LIBRARY BY INTRODUCTION OF A SEMI-SOLID MRNA - CDNA HYBRIDIZATION SYSTEM", NUCLEIC ACIDS RESEARCH, INFORMATION RETRIEVAL LTD, GB, (19940201), vol. 22, no. 6, ISSN 0305-1048, pages 987 - 992, XP002925571 [A] 1-15 * the whole document *-
SEARCH- SLATER R J, "The purification of poly(a)-containing RNA by affinity chromatography; Chapter 16", SLATER R J, John M. Walker, (Ed.), METHODS IN MOLECULAR BIOLOGY, New York, US;, Springer Verlag, (1985), pages 117 - 120, ISSN 1064-3745, XP001314843 [A] 1-15 * the whole document *-
SEARCH- SMITH J C ET AL, "Purification of polynucleotide phosphorylase by affinity chromatography and some properties of the purified enzymes.", NUCLEIC ACIDS RESEARCH DEC 1974, (197412), vol. 1, no. 12, ISSN 0305-1048, pages 1763 - 1773, XP002761806 [A] 1-15 * the whole document *-
SEARCH- "SUBTRACTIVE HYBRIDIZATION STRATEGY USING PARAMAGNETIC OLIGO(DT) BEADS AND PCR", BIOTECHNIQUES, INFORMA HEALTHCARE, US, (19960301), vol. 20, no. 3, ISSN 0736-6205, pages 413 - 419, XP000749718 [A] 1-15 * the whole document *-
SEARCH- BYNUM J W ET AL, "Characterization of subcellular poly(A) RNA populations by poly(U) Sepharose chromatography and discontinuous elution", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC, NEW YORK, vol. 107, no. 2, doi:10.1016/0003-2697(80)90402-9, ISSN 0003-2697, (19800915), pages 406 - 416, (19800915), XP024826458 [A] 1-15 * the whole document *
SEARCH- KURIBAYASHI-OHTA K ET AL, "Application of oligo(dT)30-latex for rapid purification of poly(A)<+> mRNA and for hybrid subtraction with the in situ reverse transcribed cDNA", BIOCHIMICA ET BIOPHYSICA ACTA (BBA) - GENERAL SUBJECTS, ELSEVIER, AMSTERDAM, NL, vol. 1156, no. 2, doi:10.1016/0304-4165(93)90137-W, ISSN 0304-4165, (19930213), pages 204 - 212, (19930213), XP023494072 [A] 1-15 * the whole document *

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents