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Flavanones For Use In Treating Visceral Hypersensitivity - EP3585378

The patent EP3585378 was granted to Bioactor on Apr 27, 2022. The application was originally filed on Feb 23, 2018 under application number EP18706271A. The patent is currently recorded with a legal status of "Revoked".

EP3585378

BIOACTOR
Application Number
EP18706271A
Filing Date
Feb 23, 2018
Status
Revoked
Oct 3, 2025
Grant Date
Apr 27, 2022
External Links
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Patent Citations (11) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONEP0956867
DESCRIPTIONUS2002037855
DESCRIPTIONUS2003078231
DESCRIPTIONWO0115553
DESCRIPTIONWO0126467
DESCRIPTIONWO2005094864
DESCRIPTIONWO9847534
INTERNATIONAL-SEARCH-REPORTCN101474275
INTERNATIONAL-SEARCH-REPORTCN101623366
INTERNATIONAL-SEARCH-REPORTCN102416062
INTERNATIONAL-SEARCH-REPORTWO2015006863

Non-Patent Literature (NPL) Citations (36) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
EXAMINATION- Anonymous Geneva, "Men, Ageing and Health Achieving health across the life span", (20010101), pages 1 - 63, URL: https://apps.who.int/iris/bitstream/handle/10665/66941/WHO_NMH_NPH_01.2.pdf;jsessioni, (20210226), XP055780266-
EXAMINATION- HAYASHI HIDENORI ET AL, "Molecular analysis of fecal microbiota in elderly individuals using 16S rDNA library and T-RFLP.", MICROBIOLOGY AND IMMUNOLOGY, (2003), vol. 47, no. 8, ISSN 0385-5600, pages 557 - 570, XP003017194-
EXAMINATION- Microbiomex - Flavobiotics for gut defense and immune support White paper-
EXAMINATION- KIICHIRO KAWAGUCHI ET AL, "Colony Stimulating Factor-Inducing Activity of Hesperidin", PLANTA MEDICA, DE, (19990501), vol. 65, no. 04, doi:10.1055/s-2006-960788, ISSN 0032-0943, pages 365 - 366, XP055715961
OPPOSITION- Anonymous, "Naringin", Wikipedia, (20230217), pages 1 - 4, Wikipedia, URL: https://en.wikipedia.org/wiki/Naringin, (20230217), XP093024937-
OPPOSITION- Anonymous, "Targeting the biome with a new nutritional", nutritioninsight.com, (20171024), pages 1 - 3, nutritioninsight.com, URL: https://www.nutritioninsight.com/video/targeting-the-biome-with-a-new-nutritional.html, (20230217), XP093024935-
OPPOSITION- Anonymous, "Whitepaper MicrobiomeX® improves gut barrier function and lowers gut inflammation by positively changing the gut microbiome composition", MicrobiomeX, Flavobiotic for enhancing the gut's immune function, BioActor, (20170801), pages 1 - 4, XP093024893-
OPPOSITION- Anonymous, "White Paper MicrobiomeX® supports the immune system and improves the gut defences through a unique cross-talk between citrus flavonoids and the gut microbiome", MicrobiomeX Flavobiotics® for Gut Defense & Immune Support, (20190101), pages 1 - 8, XP093024877-
OPPOSITION- D27 - (post published): guidelines for submitting a thesis at the University of Maastricht https://library.maastrichtuniversity.nl/research/sharing- output/submit-doctoral-thesisdissertation/ Current link: https://library.maastrichtuniversity.nl/research/publishing/information/publicatio ntypes/submit-doctoral-thesis-dissertation-
OPPOSITION- D28 - (Narcis database) https://netherlands.openaire.eu/search/publication?pid=10.26481%2Fdis.2017 0317bs-
OPPOSITION- D29 - (OAIster database) https://oaister.on.worldcat.org/search/detail/1363310988?queryString=Nutrition D29 al%20interventions%20focusing%20on%20gastrointestinal%20and%20metabo lic%20health&cluster Results=true&groupVariantRecords=false-
OPPOSITION- D30 - Embargo Limitations included in the License to Deposit in a Digital Repository-
OPPOSITION- D31 - Regulation governing the attainment of doctoral degrees. Maastricht University 2018-
OPPOSITION- D32 - The announcement from Maastricht University of the lecture of the thesis https://www.maastrichtuniversity.nl/events/phd-conferral-ms-bouke-nh-salden- msc-
OPPOSITION- D33 - HaCaSpect, magazine for general practitioners and specialists July 2017 publishing the lecture of the thesis-
OPPOSITION- D34a - Evidence of the date that was accessible on the internet-
OPPOSITION- D34 - “MegaMucosaTM” Mucosa Support Formula, Microbiome Labs, https://simplynutrients.com/content/pdfs/MegaMucosa- Handout.pdf?srsltid=AfmBOorRyCHJGaY0CjF7555uGuFXs8n- 3CWbhNYSaOFjLwPuZk59bvnk-
OPPOSITION- D35 - Examples A-C-
OPPOSITION- D36 - Screenshot wayback machine (internet archive)-
OPPOSITION- Gorinstein S. et al, "Determination of naringin and hesperidin in citrus fruit by high-performance liquid chromatography. The antioxidant potential of citrus fruit", ACTA CHROMATOGRAPHICA, (20060101), no. 17, pages 108 - 124, XP093024941-
OPPOSITION- HIDENORI HAYASI et al., "Molecular Analysis of Fecal Microbiota in Elderly Individual Using 16S rDNA library and T-RFLP", Microbiol. Immunol., (20030000), vol. 47, pages 557 - 570, XP003017194-
OPPOSITION- Salden B.N.H., "Nutritional interventions focusing on gastrointestinal and metabolic health", Academic theses, Leiden University, (20170101), pages 138 - 158, XP093024924-
OPPOSITION- Wikipedia, "Hesperidin", Wikipedia, (20221228), pages 1 - 5, Wikipedia, URL: https://en.wikipedia.org/wiki/Hesperidin, (20230217), XP093024930-
OPPOSITION- CHEN et al., "Development of determination of four analytes of Zhi-Shao-San decoction using LC-MS/MS and its application to comparative pharmacokinetics in normal and irritable bowel syndrome rat plasma", Biomed. Chromatogr., (20140000), vol. 28, doi:10.1002/bmc.3180, pages 1384 - 1392, XP055395024
OPPOSITION- S. G. PARKAR et al., "The potential influence of fruit polyphenols on colonic microflora and human gut health", International Journal of Food Microbiology, (20080000), vol. 124, doi:10.1016/j.ijfoodmicro.2008.03.017, pages 295 - 298, XP022672917
OPPOSITION- E. BIAGI et al., "Ageing and gut microbes: Perspectives for health maintenance and longevity", Pharmacological Research, (20130000), vol. 69, doi:10.1016/j.phrs.2012.10.005, pages 11 - 20, XP055280226
OPPOSITION- Maachi M. et al, "Systemic low-grade inflammation is related to both circulating and adipose tissue TNFα, leptin and IL-6 levels in obese women", International Journal of Obesity, Nature Publishing Group UK, London, London, (20040801), vol. 28, no. 8, doi:10.1038/sj.ijo.0802718, ISSN 0307-0565, pages 993 - 997, XP093024868
OPPOSITION- Orimo Hajime et al, "Reviewing the definition of "elderly"", GERIATRICS AND GERONTOLOGY INTERNATIONAL, Wiley-Blackwell Publishing Asia, AU, AU , (20060901), vol. 6, no. 3, doi:10.1111/j.1447-0594.2006.00341.x, ISSN 1444-1586, pages 149 - 158, XP093024871
OPPOSITION- Tchkonia Tamara et al, "Fat tissue, aging, and cellular senescence : Fat tissue and aging", AGING CELL, BLACKWELL PUBLISHING,, GB, GB , (20101001), vol. 9, no. 5, doi:10.1111/j.1474-9726.2010.00608.x, ISSN 1474-9718, pages 667 - 684, XP093024943
OPPOSITION- CLAUDIO FRANCESCHI et al, "Inflamm‐aging: An Evolutionary Perspective on Immunosenescence", Annals of the New York Academy of Sciences, New York Academy of Sciences., US, US , (20060125), vol. 908, no. 1, doi:10.1111/j.1749-6632.2000.tb06651.x, ISSN 0077-8923, pages 244 - 254, XP071392180
OPPOSITION- Pérez Laura M. et al, "‘Adipaging’: ageing and obesity share biological hallmarks related to a dysfunctional adipose tissue", The Journal of Physiology, Wiley-Blackwell Publishing Ltd., GB, GB , (20160615), vol. 594, no. 12, doi:10.1113/JP271691, ISSN 0022-3751, pages 3187 - 3207, XP093024945
OPPOSITION- Poullis Andrew et al, "Bowel inflammation as measured by fecal calprotectin: A link between lifestyle factors and colorectal cancer risk", Cancer epidemiology, biomarkers & prevention, American Association for Cancer Research, (20040101), vol. 13, no. 2, doi:10.1158/1055-9965.EPI-03-0160, ISSN 1055-9965, pages 279 - 284, XP093024951
OPPOSITION- Satya Prakash et al, "Gut microbiota: next frontier in understanding human health and development of biotherapeutics", Biologics: Targets and Therapy, doi:10.2147/BTT.S19099, pages 71 - 86, XP055382179
OPPOSITION- Salden Bouke Nicolette Hubertus, " Nutritional interventions focusing on gastrointestinal and metabolic health", Doctoral Dissertation, Maastricht University, vol. 23, no. 1217, doi:10.26481/dis.20170317bs, ISBN 978-94-6333-129-6, pages 390 - 405, Doctoral Dissertation, Maastricht University, URL: https://cris.maastrichtuniversity.nl/ws/portalfiles/portal/11183241/c5603.pdf, XP093270024
OPPOSITION- Alam M. Ashraful et al, "Effect of Citrus Flavonoids, Naringin and Naringenin, on Metabolic Syndrome and Their Mechanisms of Action", ADVANCES IN NUTRITION, American Society for Nutrition, United States, United States , (20140701), vol. 5, no. 4, doi:10.3945/an.113.005603, ISSN 2161-8313, pages 404 - 417, XP093024953
OPPOSITION- Shengyong Mao, "Effects of six flavonoid compounds addition on short-chain fatty acids production and human fecal microbial community change during in vitro fermentation", African Journal of Microbiology Research, (20111116), vol. 5, no. 26, doi:10.5897/AJMR11.291, pages 4484 - 4491, XP093024946

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