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Systems And Methods To Detect Rare Mutations And Copy Number Variation - EP3591073

The patent EP3591073 was granted to Guardant Health on Dec 1, 2021. The application was originally filed on Sep 4, 2013 under application number EP19192885A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3591073

GUARDANT HEALTH
Application Number
EP19192885A
Filing Date
Sep 4, 2013
Status
Granted And Under Opposition
Oct 29, 2021
Publication Date
Dec 1, 2021
External Links
Slate, Register, Google Patents

Patent Summary

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Patent Family

Patent Oppositions (2)

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GRUNECKER PATENT UND RECHTSANWALTE PARTG MBBSep 1, 2022GRUNECKER PATENTADMISSIBLE
MARGARET DIXONSep 1, 2022MEWBURN ELLISADMISSIBLE

Patent Citations (17) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONUS2001053519
DESCRIPTIONUS2003152490
DESCRIPTIONUS2011160078
DESCRIPTIONUS6582908
DESCRIPTIONUS7537897
OPPOSITIONUS2011160078
OPPOSITIONUS2012165202
OPPOSITIONUS2013137588
OPPOSITIONUS8481292
OPPOSITIONWO2012042374
OPPOSITIONWO2012142213
OPPOSITIONWO2012148477
OPPOSITIONWO2013138510
OPPOSITIONWO2013142389
SEARCHUS8209130
SEARCHWO2008154317
SEARCHWO2014149134

Non-Patent Literature (NPL) Citations (26) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
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OPPOSITION- KIVIOJA et al., "Counting absolute numbers of molecules using unique molecular identifiers", Nature Preceedings: hdl:10101/npre.2011.5903.1, (20110414), pages 1 - 32, XP055960230
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OPPOSITION- Fleischhacker, M. Schmidt, B., "Circulating nucleic acids (CNAs) and cancer-A survey", Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, ELSEVIER SCIENCE BV, AMSTERDAM., NL, NL , (20061213), vol. 1775, no. 1, doi:10.1016/j.bbcan.2006.10.001, ISSN 0304-419X, pages 181 - 232, XP005802356
OPPOSITION- Teemu Kivioja, Anna Vähärautio, Kasper Karlsson, Martin Bonke, Martin Enge, Sten Linnarsson, Jussi Taipale, "Counting absolute numbers of molecules using unique molecular identifiers.", NATURE METHODS, Nature Publishing Group, GB, GB , (20120101), vol. 9, no. 1, doi:10.1038/nmeth.1778, ISSN 1548-7105, pages 72 - 74, XP002729237
OPPOSITION- Heidi Schwarzenbach, Dave S. B. Hoon, Klaus Pantel, "Cell-free nucleic acids as biomarkers in cancer patients", Nature Reviews Cancer, Nature Pub. Group, London, London , (20110601), vol. 11, no. 6, doi:10.1038/nrc3066, ISSN 1474-175X, pages 426 - 437, XP055247315
OPPOSITION- DIEHL et al., "Analysis of mutations in DNA isolated from plasma and stool of colorectal cancer patients", Gastroenterology, (20080000), vol. 135, no. 2, doi:10.1053/j.gastro.2008.05.039, page 489, XP023901355
OPPOSITION- Diehl, F. ; Schmidt, K. ; Durkee, K.H. ; Moore, K.J. ; Goodman, S.N. ; Shuber, A.P. ; Kinzler, K.W. ; Vogelstein, B., "Analysis of Mutations in DNA Isolated From Plasma and Stool of Colorectal Cancer Patients", Gastroenterology, Elsevier Inc., US, US , (20080801), vol. 135, no. 2, doi:10.1053/j.gastro.2008.05.039, ISSN 0016-5085, pages 489 - 498.e7, XP023901355
OPPOSITION- FAN et al., "Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood", PNAS, (20081021), vol. 105, no. 42, doi:10.1073/pnas.0808319105, pages 16266 - 16271, XP055523982
OPPOSITION- H. C. Fan, Y. J. Blumenfeld, U. Chitkara, L. Hudgins, S. R. Quake, "Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20081021), vol. 105, no. 42, doi:10.1073/pnas.0808319105, ISSN 0027-8424, pages 16266 - 16271, XP055687023
OPPOSITION- R. W. K. Chiu, K. C. A. Chan, Y. Gao, V. Y. M. Lau, W. Zheng, T. Y. Leung, C. H. F. Foo, B. Xie, N. B. Y. Tsui, F. M. F. Lun, B. C. Y. Zee, T. K. Lau, C. R. Cantor, Y. M. D. Lo, "Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20081223), vol. 105, no. 51, doi:10.1073/pnas.0810641105, ISSN 0027-8424, pages 20458 - 20463, XP055284693
OPPOSITION- G. K. Fu, J. Hu, P.-H. Wang, S. P. A. Fodor, "Counting individual DNA molecules by the stochastic attachment of diverse labels", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20110531), vol. 108, no. 22, doi:10.1073/pnas.1017621108, ISSN 0027-8424, pages 9026 - 9031, XP055694849
OPPOSITION- KINDE et al., "Detection and quantification of rare mutations with massively parallel sequencing", PNAS, (20110607), vol. 108, no. 23, doi:10.1073/pnas.1105422108, pages 9530 - 9535, XP055815700
OPPOSITION- Kinde I., Wu J., Papadopoulos N., Kinzler K. W., Vogelstein B., "Detection and quantification of rare mutations with massively parallel sequencing", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20110607), vol. 108, no. 23, doi:10.1073/pnas.1105422108, ISSN 0027-8424, pages 9530 - 9535, XP055855692
OPPOSITION- M. W. Schmitt, S. R. Kennedy, J. J. Salk, E. J. Fox, J. B. Hiatt, L. A. Loeb, "Detection of ultra-rare mutations by next-generation sequencing", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20120904), vol. 109, no. 36, doi:10.1073/pnas.1208715109, ISSN 00278424, pages 14508 - 14513, XP055161683
OPPOSITION- SCHMITT et al., "Detection of ultra-rare mutations by next-generation sequencing", PNAS, (20120904), vol. 109, no. 36, doi:10.1073/pnas.1208715109, pages 14508 - 14513, XP055928698
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OPPOSITION- CASBON et al., "A method for counting PCR template molecules with application to next-generation sequencing", Nucleic Acids Research, (20110701), vol. 39, no. 12, doi:10.1093/nar/gkr217, page e81, XP055574095
OPPOSITION- T. Forshew, Murtaza M., Parkinson C., Gale D., Tsui D. W. Y., Kaper F., Dawson S.-J., Piskorz A. M., Jimenez-Linan M., Bentley D., Hadfield J., May A. P., Caldas C., Brenton J. D., Rosenfeld N., "Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA /Supplementary Materials/", Science Translational Medicine, doi:10.1126/scitranslmed.3003726, (20120530), pages 1 - 19, Science Translational Medicine, URL: https://stm.sciencemag.org/content/scitransmed/suppl/2012/05/25/4.136.136ra68.DC1/4-136ra68_SM.pdf, (20191126), XP055646640
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SEARCH- M. W. SCHMITT ET AL, "Detection of ultra-rare mutations by next-generation sequencing", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20120801), vol. 109, no. 36, doi:10.1073/pnas.1208715109, ISSN 0027-8424, pages 14508 - 14513, XP055161683 [A] 1-15 * page 14509, column l, paragraph l - column r, paragraph 2 * * figure 1 *

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