IP Verse

Methods For Improving Safety Of Blood-Brain Barrier Transport - EP3594239

The patent EP3594239 was granted to F Hoffmann LA Roche on Oct 30, 2024. The application was originally filed on May 20, 2013 under application number EP19189279A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3594239

F HOFFMANN LA ROCHE
Application Number
EP19189279A
Filing Date
May 20, 2013
Status
Granted And Under Opposition
Sep 27, 2024
Publication Date
Oct 30, 2024
External Links
Slate, Register, Google Patents

Patent Summary

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Patent Family

Patent Oppositions (2)

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ZWICKER SCHNAPPAUF & PARTNERJul 30, 2025ZWICKERADMISSIBLE
JAMES POOLEJul 16, 2025CARPMAELS & RANSFORDADMISSIBLE

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EXAMINATION- COUCH JESSICA A ET AL, "Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier.", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, (20130501), Database accession no. NLM23636093
EXAMINATION- YU Y JOY ET AL, "Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target.", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, (20110525), Database accession no. NLM21613623
EXAMINATION- YU Y JOY ET AL, "Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target.", SCIENCE TRANSLATIONAL MEDICINE 25 MAY 2011, (20110525), vol. 3, no. 84, ISSN 1946-6242, page 84ra44
EXAMINATION- COUCH JESSICA A ET AL, "Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier.", SCIENCE TRANSLATIONAL MEDICINE 01 MAY 2013, (20130501), vol. 5, no. 183, doi:10.1126/scitranslmed.3005338, ISSN 1946-6242, pages 183ra57 , 1 - 12, XP008163922
OPPOSITION- D8 - Patentee’s letter to EPO 13 May 2024
OPPOSITION- Yu Y Joy; Zhang Yin; Kenrick Margaret; Hoyte Kwame; Luk Wilman; Lu Yanmei; Atwal Jasvinder; Elliott J Michael; Prabhu Saileta; Watts Ryan J; Dennis Mark S, "Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target.", SCIENCE TRANSLATIONAL MEDICINE, American Association for the Advancement of Science (A A A S), US, US , (20110525), vol. 3, no. 84 84ra44, doi:10.1126/scitranslmed.3002230, ISSN 1946-6242, pages 1 - 8, XP008148394
OPPOSITION- Paul Steven M, "Therapeutic antibodies for brain disorders", SCIENCE TRANSLATIONAL MEDICINE, American Association for the Advancement of Science (A A A S), US, US , (20110525), vol. 3, no. 84, doi:10.1126/scitranslmed.3002620, ISSN 1946-6242, page 84ps20, XP009155720
OPPOSITION- Jessica A. Couch et al., "Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier", ScienceTranslationalMedicine, (20130501), vol. 5, doi:10.1126/scitranslmed.3005338, page 183, XP008163922
SEARCH- YU Y JOY ET AL, "Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target", SCIENCE / SCIENCE TRANSLATIONAL MEDICINE, WASHINGTON, DC : AAAS, US, (20110525), vol. 3, no. 84, doi:10.1126/SCITRANSLMED.3002230, ISSN 1946-6242, pages 1 - 8, XP008148394 [ID] 1-21 * the whole document *
SEARCH- PAUL STEVEN M, "Therapeutic antibodies for brain disorders", SCIENCE / SCIENCE TRANSLATIONAL MEDICINE, WASHINGTON, DC : AAAS, US, (20110525), vol. 3, no. 84, ISSN 1946-6242, page 84ps20, XP009155720 [I] 1-21 * whole document, especially the Abstract; page 2, right-hand column, and page 3 *
SEARCH- COUCH JESSICA A ET AL, "Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier.", SCIENCE TRANSLATIONAL MEDICINE 1 MAY 2013, (20130501), vol. 5, no. 183, ISSN 1946-6242, page 12, XP008163922 [IP] 1-21 * whole document, especially the Abstract; page 55, lower part of right-hand column; page 62, section "Antibody and bispecific antibody production"; Figures 5-6 *

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