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Methods For Improving Safety Of Blood-Brain Barrier Transport - EP3594239

The patent EP3594239 was granted to F Hoffmann LA Roche on Oct 30, 2024. The application was originally filed on May 20, 2013 under application number EP19189279A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3594239

F HOFFMANN LA ROCHE
Application Number
EP19189279A
Filing Date
May 20, 2013
Status
Granted And Under Opposition
Sep 27, 2024
Grant Date
Oct 30, 2024
External Links
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Patent Oppositions (2)

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ZWICKER SCHNAPPAUF & PARTNERJul 30, 2025ADMISSIBLE
JAMES POOLEJul 16, 2025ADMISSIBLE

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OPPOSITION- Yu Y Joy; Zhang Yin; Kenrick Margaret; Hoyte Kwame; Luk Wilman; Lu Yanmei; Atwal Jasvinder; Elliott J Michael; Prabhu Saileta; Watts Ryan J; Dennis Mark S, "Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target.", SCIENCE TRANSLATIONAL MEDICINE, American Association for the Advancement of Science (A A A S), US, US , (20110525), vol. 3, no. 84 84ra44, doi:10.1126/scitranslmed.3002230, ISSN 1946-6242, pages 1 - 8, XP008148394
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SEARCH- YU Y JOY ET AL, "Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target", SCIENCE / SCIENCE TRANSLATIONAL MEDICINE, WASHINGTON, DC : AAAS, US, (20110525), vol. 3, no. 84, doi:10.1126/SCITRANSLMED.3002230, ISSN 1946-6242, pages 1 - 8, XP008148394 [ID] 1-21 * the whole document *
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SEARCH- COUCH JESSICA A ET AL, "Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier.", SCIENCE TRANSLATIONAL MEDICINE 1 MAY 2013, (20130501), vol. 5, no. 183, ISSN 1946-6242, page 12, XP008163922 [IP] 1-21 * whole document, especially the Abstract; page 55, lower part of right-hand column; page 62, section "Antibody and bispecific antibody production"; Figures 5-6 *

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