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| OPPOSITION | - Tomas Cermak, Erin L Doyle, Michelle Christian, Li Wang, Yong Zhang, Clarice Schmidt, Joshua A Baller, Nikunj V Somia, Adam J Bogdanove and Daniel F Voytas, "Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting.", Nucleic Acids research, Oxford University Press, GB, GB , (20110701), vol. 39, no. 12, doi:10.1093/nar/gkr218, ISSN 1362-4962, pages 1 - 11, XP002659530 |
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| OPPOSITION | - J. E. Dicarlo, J. E. Norville, P. Mali, X. Rios, J. Aach, G. M. Church, "Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems", Nucleic Acids Research, Information Retrieval Ltd., (20130401), vol. 41, no. 7, doi:10.1093/nar/gkt135, ISSN 03051048, pages 4336 - 4343, XP055086617 |
| OPPOSITION | - Chylinski K, Makarova K S, Charpentier E, Koonin E V., "Classification and evolution of type II CRISPR-Cas systems", Nucleic Acids Research, Oxford University Press, GB, GB , (20140601), vol. 42, no. 10, doi:10.1093/nar/gku241, ISSN 0305-1048, pages 6091 - 6105, XP002760958 |
| OPPOSITION | - H. J. Kim, H. J. Lee, S. W. Cho, J.-S. Kim, "Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly", Genome Research, Cold Spring Harbor Laboratory Press, (20090701), vol. 19, no. 7, doi:10.1101/gr.089417.108, ISSN 10889051, pages 1279 - 1288, XP055143646 |
| OPPOSITION | - H. J. Lee, Kim E., Kim J.-S., "Targeted chromosomal deletions in human cells using zinc finger nucleases", Genome Research, Cold Spring Harbor Laboratory Press, (20100101), vol. 20, no. 1, doi:10.1101/gr.099747.109, ISSN 10889051, pages 81 - 89, XP055077115 |
| OPPOSITION | - E. Kim, S. Kim, D. H. Kim, B.-S. Choi, I.-Y. Choi, J.-S. Kim, "Precision genome engineering with programmable DNA-nicking enzymes", Genome Research, Cold Spring Harbor Laboratory Press, (20120701), vol. 22, no. 7, doi:10.1101/gr.138792.112, ISSN 10889051, pages 1327 - 1333, XP055106309 |
| OPPOSITION | - M. Maresca, Lin V. G., Guo N., Yang Y., "Obligate Ligation-Gated Recombination (ObLiGaRe): Custom-designed nuclease-mediated targeted integration through nonhomologous end joining", Genome Research, Cold Spring Harbor Laboratory Press, (20130301), vol. 23, no. 3, doi:10.1101/gr.145441.112, ISSN 10889051, pages 539 - 546, XP055077484 |
| OPPOSITION | - S. W. Cho, S. Kim, Y. Kim, J. Kweon, H. S. Kim, S. Bae, J.-S. Kim, "Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases", Genome Research, Cold Spring Harbor Laboratory Press, US, US , (20140101), vol. 24, no. 1, doi:10.1101/gr.162339.113, ISSN 1088-9051, pages 132 - 141, XP055227885 |
| OPPOSITION | - PORTEUS M H, BALTIMORE D, "Chimeric nucleases stimulate gene targeting in human cells", Science, American Association for the Advancement of Science, US, US , (20030502), vol. 300, doi:10.1126/science.1078395, ISSN 0036-8075, page 763, XP002974231 |
| OPPOSITION | - BIBIKOVA M, ET AL., "Enhancing gene targeting with designed zinc finger nucleases", Science, American Association for the Advancement of Science, US, US , (20030502), vol. 300, doi:10.1126/science.1079512, ISSN 0036-8075, page 764, XP002974267 |
| OPPOSITION | - GEURTS ARON M ET AL, "Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases", Science, American Association for the Advancement of Science, US, US , (20090724), vol. 325, no. 5939, doi:10.1126/SCIENCE.1172447, ISSN 0036-8075, page 433, XP002580718 |
| OPPOSITION | - M. Jinek, K. Chylinski, I. Fonfara, M. Hauer, J. A. Doudna, E. Charpentier, "A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity", Science, American Association for the Advancement of Science, (20120817), vol. 337, no. 6096, doi:10.1126/science.1225829, ISSN 00368075, pages 816 - 821, XP055067740 |
| OPPOSITION | - S. J. J. Brouns, "A Swiss Army Knife of Immunity", Science, American Association for the Advancement of Science, (20120817), vol. 337, no. 6096, doi:10.1126/science.1227253, ISSN 00368075, pages 808 - 809, XP055113718 |
| OPPOSITION | - L. Cong, F. A. Ran, D. Cox, S. Lin, R. Barretto, N. Habib, P. D. Hsu, X. Wu, W. Jiang, L. A. Marraffini, F. Zhang, "Multiplex Genome Engineering Using CRISPR/Cas Systems", Science, American Association for the Advancement of Science, (20130215), vol. 339, no. 6121, doi:10.1126/science.1231143, ISSN 00368075, pages 819 - 823, XP055067741 |
| OPPOSITION | - P. Mali, L. Yang, K. M. Esvelt, J. Aach, M. Guell, J. E. Dicarlo, J. E. Norville, G. M. Church, "RNA-Guided Human Genome Engineering via Cas9", Science, American Association for the Advancement of Science, (20130215), vol. 339, no. 6121, doi:10.1126/science.1232033, ISSN 00368075, pages 823 - 826, XP055111247 |
| OPPOSITION | - John Van Der Oost, "New tool for genome surgery", Science, American Association for the Advancement of Science, US, US , (20130215), vol. 339, no. 6121, doi:10.1126/science.1234726, ISSN 1095-9203, pages 768 - 770, XP055185006 |
| OPPOSITION | - T. Xu, Y. Li, J. D. Van Nostrand, Z. He, J. Zhou, "Cas9-Based Tools for Targeted Genome Editing and Transcriptional Control", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, American Society for Microbiology, US, US , (20140301), vol. 80, no. 5, doi:10.1128/AEM.03786-13, ISSN 0099-2240, pages 1544 - 1552, XP055290296 |
| OPPOSITION | - J. S. Lee, A. G. Hadjipanayis, S. L. Welkos, "Venezuelan Equine Encephalitis Virus-Vectored Vaccines Protect Mice against Anthrax Spore Challenge", Infection and immunity, American Society for Microbiology, US, US , (20030301), vol. 71, no. 3, doi:10.1128/IAI.71.3.1491-1496.2003, ISSN 0019-9567, pages 1491 - 1496, XP055519514 |
| OPPOSITION | - ROUET P., SMIH F., JASIN M., "Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease.", MOLECULAR AND CELLULAR BIOLOGY, American Society for Pharmacology and Experimental Therapeutics, US, US , (19941201), vol. 14., no. 12., doi:10.1128/mcb.14.12.8096, ISSN 0270-7306, pages 8096 - 8106, XP000572018 |
| OPPOSITION | - D. G. Miller, L. M. Petek, D. W. Russell, "Human Gene Targeting by Adeno-Associated Virus Vectors Is Enhanced by DNA Double-Strand Breaks", MOLECULAR AND CELLULAR BIOLOGY, American Society for Pharmacology and Experimental Therapeutics, US, US , (20030515), vol. 23, no. 10, doi:10.1128/MCB.23.10.3550-3557.2003, ISSN 0270-7306, pages 3550 - 3557, XP055502623 |
| OPPOSITION | - N Rudin, J E Haber, "Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences", Molecular and Cellular Biology, American Society for Microbiology, United States, United States , doi:10.1128/MCB.8.9.3918, (19880901), pages 3918 - 3928, Molecular and Cellular Biology, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC365451/pdf/molcellb00069-0358.pdf, XP055502440 |
| OPPOSITION | - Michael R. Lieber, "The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway", ANNUAL REVIEW OF BIOCHEMISTRY, PALTO ALTO, CA, US, US , (20100607), vol. 79, no. 1, doi:10.1146/annurev.biochem.052308.093131, ISSN 0066-4154, pages 181 - 211, XP055340167 |
| OPPOSITION | - Symington Lorraine S., Gautier Jean, "Double-Strand Break End Resection and Repair Pathway Choice", ANNUAL REVIEW OF GENETICS., ANNUAL REVIEWS INC., PALO ALTO, CA, US, US , (20111215), vol. 45, no. 1, doi:10.1146/annurev-genet-110410-132435, ISSN 0066-4197, pages 247 - 271, XP093236903 |
| OPPOSITION | - Ketola Anna, Hinkkanen Ari, Yongabi Felicitas, Furu Petra, Määttä Ann-Marie, Liimatainen Timo, Pirinen Risto, Björn Marko, Hakkarainen Tanja, Mäkinen Kimmo, Wahlfors Jarmo, Pellinen Riikka, "Oncolytic Semliki Forest Virus Vector as a Novel Candidate against Unresectable Osteosarcoma", Cancer research, American Association for Cancer Research, US, US, (20081015), vol. 68, no. 20, doi:10.1158/0008-5472.CAN-08-0251, ISSN 0008-5472, pages 8342 - 8350, XP055983305 |
| OPPOSITION | - Jensen Nanna M; Dalsgaard Trine; Jakobsen Maria; Nielsen Roni R; SÃ ̧rensen Charlotte B; Bolund Lars; Jensen Thomas G, "An update on targeted gene repair in mammalian cells: methods and mechanisms", Journal of Biomedical Science, Kluwer Academic Publishers, Do, Do , (20110202), vol. 18, no. 1, doi:10.1186/1423-0127-18-10, ISSN 1423-0127, pages 1 - 10, XP021085735 |
| OPPOSITION | - Brice V McConnell;Karen Koto;Arthur Gutierrez-Hartmann, "Nuclear and cytoplasmic LIMK1 enhances human breast cancer progression", MOLECULAR CANCER, BIOMED CENTRAL, LONDON, GB, GB , (20110618), vol. 10, no. 1, doi:10.1186/1476-4598-10-75, ISSN 1476-4598, pages 1 - 13, XP021103688 |
| OPPOSITION | - Wuyang Zhu;Jiangjiao Li;Li Tang;Huanqin Wang;Jia Li;Juanjuan Fu;Guodong Liang, "Glycoprotein is enough for sindbis virus-derived DNA vector to express heterogenous genes", VIROLOGY JOURNAL, BIOMED CENTRAL, LONDON, GB, GB , (20110710), vol. 8, no. 1, doi:10.1186/1743-422X-8-344, ISSN 1743-422X, page 344, XP021105747 |
| OPPOSITION | - Inga Freunscht;Bernt Popp;Rainer Blank;Sabine Endele;Ute Moog;Holger Petri;Eva-Christina Prott;Andre Reis;Jochen Rübo;Bernhard Zabel;Martin Zenker;Johannes Hebebrand;Dagmar Wieczorek , "Behavioral phenotype in five individuals with de novo mutations within the GRIN2B gene", BEHAVIORAL AND BRAIN FUNCTIONS, BIOMED CENTRAL, LONDON, GB, GB , (20130529), vol. 9, no. 1, doi:10.1186/1744-9081-9-20, ISSN 1744-9081, page 20, XP021153545 |
| OPPOSITION | - Kira S Makarova;L Aravind;Yuri I Wolf;Eugene V Koonin, "Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems", Biology Direct, BioMed Central, (20110714), vol. 6, no. 1, doi:10.1186/1745-6150-6-38, ISSN 1745-6150, pages 1 - 27, XP021105829 |
| OPPOSITION | - Chieh Chang, Yi-Wen Hsieh, Bluma J. Lesch, Cornelia I. Bargmann, Chiou-Fen Chuang, "Microtubule-based localization of a synaptic calcium-signaling complex is required for left-right neuronal asymmetry in C. elegans", Development, The Company of Biologists Ltd., GB, GB , (20110815), vol. 138, no. 16, doi:10.1242/dev.069740, ISSN 0950-1991, pages 3509 - 3518, XP055502632 |
| OPPOSITION | - Keisuke Sato, Et Al, "Generation of Adeno-Associated Virus Vector Enabling Functional Expression of Oxytocin Receptor and Fluorescence Marker Genes Using the Human eIF4G Internal Ribosome Entry Site Element", Bioscience, Biotechnology, and Biochemistry, Japan Society for Bioscience, Biotechnology, and Agrochemistry, JP, JP , (20090923), vol. 73, no. 9, doi:10.1271/bbb.90287, ISSN 0916-8451, pages 2145 - 2148, XP055487142 |
| OPPOSITION | - Christopher S. Raymond, Philippe Soriano, "High-Efficiency FLP and ΦC31 Site-Specific Recombination in Mammalian Cells", PLOS ONE, Public Library of Science, US, US , (20070101), vol. 2, no. 1, doi:10.1371/journal.pone.0000162, ISSN 1932-6203, pages e162/1 - 4, XP055069825 |
| OPPOSITION | - Woong Y. Hwang, Yanfang Fu, Deepak Reyon, Morgan L. Maeder, Prakriti Kaini, Jeffry D. Sander, J. Keith Joung, Randall T. Peterson, Jing-Ruey Joanna Yeh, "Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System", PLoS ONE, vol. 8, no. 7, doi:10.1371/journal.pone.0068708, page e68708, XP055196397 |
| OPPOSITION | - D. Carroll, "Genome Engineering With Zinc-Finger Nucleases", Genetics, Genetics Society of America [etc.], (20110801), vol. 188, no. 4, doi:10.1534/genetics.111.131433, ISSN 00166731, pages 773 - 782, XP055036700 |
| OPPOSITION | - S. J. Gratz, A. M. Cummings, J. N. Nguyen, D. C. Hamm, L. K. Donohue, M. M. Harrison, J. Wildonger, K. M. O'connor-Giles, "Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease", Genetics, Genetics Society of America [etc.], (20130801), vol. 194, no. 4, doi:10.1534/genetics.113.152710, ISSN 00166731, pages 1029 - 1035, XP055102690 |
| OPPOSITION | - Christian Frøkjær-Jensen, "Exciting Prospects for Precise Engineering of Caenorhabditis elegans Genomes with CRISPR/Cas9", Genetics, (20131101), vol. 195, no. 3, doi:10.1534/genetics.113.156521, ISSN 1943-2631, pages 635 - 642, XP093160358 |
| OPPOSITION | - Nicholas Lyssenko, Hanna-Rose Wendy, Schlegel Robert, "Cognate putative nuclear localization signal effects strong nuclear localization of a GFP reporter and facilitates gene expression studies in Caenorhabditis elegans", Biotechniques, Informa Healthcare, US, US , (20071101), vol. 43, no. 5, doi:10.2144/000112615, ISSN 0736-6205, pages 596 - 600, XP055268137 |
| OPPOSITION | - Teng Man, Yao Yongxiu, Nair Venugopal, Luo Jun, "Latest Advances of Virology Research Using CRISPR/Cas9-Based Gene-Editing Technology and Its Application to Vaccine Development", Viruses, MDPI, CH, CH , (20210428), vol. 13, no. 5, doi:10.3390/v13050779, ISSN 1999-4915, page 779, XP093147119 |
| OPPOSITION | - Krzysztof Chylinski, Anaïs Le Rhun, Emmanuelle Charpentier, "The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems", RNA Biology, Landes Bioscience, (20130501), vol. 10, no. 5, doi:10.4161/rna.24321, ISSN 15476286, pages 726 - 737, XP055116068 |
| OPPOSITION | - Martin Jinek, Alexandra East, Aaron Cheng, Steven Lin, Enbo Ma, Jennifer Doudna, "RNA-programmed genome editing in human cells.", eLife, eLife Sciences Publications Ltd., GB, GB , (20130129), vol. 2, doi:10.7554/eLife.00471, ISSN 2050-084X, pages e00471 - e00471-9, XP002699851 |
| SEARCH | - PABLO PEREZ-PINERA ET AL, "Synergistic and tunable human gene activation by combinations of synthetic transcription factors", NATURE METHODS, (20130203), vol. 10, no. 3, doi:10.1038/nmeth.2361, ISSN 1548-7091, pages 239 - 242, XP055206832 [A] 1-15 * abstract; figure 1A * |
| SEARCH | - MORGAN L MAEDER ET AL, "Robust, synergistic regulation of human gene expression using TALE activators", HHS PUBLIC ACCESS AUTHOR MANUSCRIPT, GB, (20130210), vol. 10, no. 3, doi:10.1038/nmeth.2366, ISSN 1548-7091, pages 243 - 245, XP055291624 [A] 1-15 * abstract * |
| SEARCH | - P. MALI ET AL, "Supplementary Materials for RNA-Guided Human Genome Engineering via Cas9", SCIENCE, (20130103), vol. 339, no. 6121, doi:10.1126/science.1232033, ISSN 0036-8075, pages 1 - 36, XP055322657 [A] 1-15 * the whole document * |
