IP Verse

Novel Crispr Enzymes And Systems - EP3604532

The patent EP3604532 was granted to Massachusetts Institute OF Technology on May 1, 2024. The application was originally filed on Jun 17, 2016 under application number EP19171732A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3604532

MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Application Number
EP19171732A
Filing Date
Jun 17, 2016
Status
Granted And Under Opposition
Mar 29, 2024
Grant Date
May 1, 2024
External Links
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COOLEY UKFeb 3, 2025SCHIWECK WEINZIERL KOCH PATENTANWALTE PARTNERSCHAFT MBBADMISSIBLE
JAMES POOLEFeb 3, 2025CARPMAELS & RANSFORDADMISSIBLE
MAIWALDJan 31, 2025MAIWALDADMISSIBLE
GRUND IPG PATENTANWALTE UND SOLICITOR PARTG MBBNov 13, 2024GRUNDADMISSIBLE

Patent Citations (8) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
OPPOSITIONWO2014093712
OPPOSITIONWO2014191521
OPPOSITIONWO2016166340
OTHERWO2014191521
OTHERWO2016166340
OTHERWO2021133977
SEARCHWO2016205749
SEARCHWO2016205764

Non-Patent Literature (NPL) Citations (60) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
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OPPOSITION- Chen Weizhong, Ma Jiacheng, Wu Zhaowei, Wang Zhipeng, Zhang Hongyuan, Fu Wenhan, Pan Deng, Shi Jin, Ji Quanjiang, "Cas12n nucleases, early evolutionary intermediates of type V CRISPR, comprise a distinct family of miniature genome editors", Molecular Cell, AMSTERDAM, NL, (20230803), vol. 83, no. 15, doi:10.1016/j.molcel.2023.06.014, ISSN 1097-2765, pages 2768 - 2780.e6, XP093230292
OPPOSITION- Koonin Eugene V., Gootenberg Jonathan S., Abudayyeh Omar O., "Discovery of Diverse CRISPR-Cas Systems and Expansion of the Genome Engineering Toolbox", Biochemistry, (20231219), vol. 62, no. 24, doi:10.1021/acs.biochem.3c00159, ISSN 0006-2960, pages 3465 - 3487, XP093259575
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OPPOSITION- Cho Seung Woo, Kim Sojung, Kim Jong Min, Kim Jin-Soo, "Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease", Nature Biotechnology, New York, (20130301), vol. 31, no. 3, doi:10.1038/nbt.2507, ISSN 1087-0156, pages 230 - 232, XP093259700
OPPOSITION- Wenyan Jiang, Bikard David, Cox David, Zhang Feng, Marraffini Luciano A, "CRISPR-assisted editing of bacterial genomes", HHS Public Access Author Manuscript, (20130301), vol. 31, no. 3, doi:10.1038/nbt.2508, pages 1 - 23, XP055458321
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OPPOSITION- Sergey Shmakov, Aaron Smargon, David Scott, David Cox, Neena Pyzocha, Winston Yan, Omar O. Abudayyeh, Jonathan S. Gootenberg, Kira S. Makarova, Yuri I. Wolf, Konstantin Severinov, Feng Zhang, Eugene V. Koonin, "Diversity and evolution of class 2 CRISPR-Cas systems.", Nature Reviews Microbiology- Author manuscript, England , (20170301), vol. 15, no. 3, doi:10.1038/nrmicro.2016.184, ISSN 1740-1534, pages 169 - 182, XP002767857
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OPPOSITION- Strecker Jonathan, Jones Sara, Koopal Balwina, Schmid-Burgk Jonathan, Zetsche Bernd, Gao Linyi, Makarova Kira S., Koonin Eugene V., Zhang Feng, "Engineering of CRISPR-Cas12b for human genome editing", Nature Communications, (20191201), vol. 10, no. 1, doi:10.1038/s41467-018-08224-4, pages 1 - 8, XP055792773
OPPOSITION- Li Danyuan, Zhang Shouyue, Lin Shuo, Xing Wenjing, Yang Yun, Zhu Fengxia, Su Dingding, Chen Chunlai, Liu Jun-Jie Gogo, "Cas12e orthologs evolve variable structural elements to facilitate dsDNA cleavage", Nature Communications, UK, (20240101), vol. 15, no. 1, doi:10.1038/s41467-024-54491-9, ISSN 2041-1723, pages 1 - 14, XP093259606
OPPOSITION- Makarova Kira S.; Wolf Yuri I.; Iranzo Jaime; Shmakov Sergey A.; Alkhnbashi Omer S.; Brouns Stan J. J.; Charpentier Emmanuelle; Cheng David; Haft Daniel H.; Horvath Philippe; Moineau Sylvain; Mojica Francisco J. M.; Scott David; Shah Shiraz A.; Siksnys Virginijus; Terns Michael P.; Venclovas ÄŒeslovas; White Malcolm F.; Yakunin Alexander F.; Yan Winston; Zhang Feng; Garrett Roger A.; Backofen Rolf; van der Oost John; Barrangou Rodolphe; Koonin Eugene V., "Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants", Nature Reviews Microbiology, GB , (20191219), vol. 18, no. 2, doi:10.1038/s41579-019-0299-x, ISSN 1740-1526, pages 67 - 83, XP036990744
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OPPOSITION- Jiang Kaiyi, Lim Justin, Sgrizzi Samantha, Trinh Michael, Kayabolen Alisan, Yutin Natalya, Bao Weidong, Kato Kazuki, Koonin Eugene V., Gootenberg Jonathan S., Abudayyeh Omar O., "Programmable RNA-guided DNA endonucleases are widespread in eukaryotes and their viruses", Science Advances, US , (20230927), vol. 9, no. 39, doi:10.1126/sciadv.adk0171, ISSN 2375-2548, pages 1 - 16, XP093115018
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OPPOSITION- Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A. Doudna, Emmanuelle Charpentier, "A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity", Science, US , (20120817), vol. 337, no. 6096, doi:10.1126/science.1225829, ISSN 0036-8075, pages 816 - 821, XP055549487
OPPOSITION- Cong Le, Ran F. Ann, Cox David, Lin Shuailiang, Barretto Robert, Habib Naomi, Hsu Patrick D., Wu Xuebing, Jiang Wenyan, Marraffini Luciano A., Zhang Feng, "Multiplex Genome Engineering Using CRISPR/Cas Systems", Science - Author Manuscript, US , (20130215), vol. 339, no. 6121, doi:10.1126/science.1231143, ISSN 0036-8075, pages 1 - 34, XP093259709
OPPOSITION- Mali Prashant, Yang Luhan, Esvelt Kevin M., Aach John, Guell Marc, Dicarlo James E., Norville Julie E., Church George M., "RNA-Guided Human Genome Engineering via Cas9", Science - Author Manuscript, US , (20130215), vol. 339, no. 6121, doi:10.1126/science.1232033, ISSN 0036-8075, pages 1 - 46, XP093259696
OPPOSITION- Lucas B. Harrington, David Burstein, Janice S. Chen, David Paez-Espino, Enbo Ma, Isaac P. Witte, Joshua C. Cofsky, Nikos C. Kyrpides, Jillian F. Banfield, Jennifer A. Doudna, "Programmed DNA destruction by miniature CRISPR-Cas14 enzymes", Science, US , (20181116), vol. 362, no. 6416, doi:10.1126/science.aav4294, ISSN 0036-8075, pages 839 - 842, XP055614750
OPPOSITION- Winston X. Yan, Pratyusha Hunnewell, Lauren E. Alfonse, Jason M. Carte, Elise Keston-Smith, Shanmugapriya Sothiselvam, Anthony J. Garrity, Shaorong Chong, Kira S. Makarova, Eugene V. Koonin, David R. Cheng, David A. Scott, "Functionally diverse type V CRISPR-Cas systems", Science, US , (20190104), vol. 363, no. 6422, doi:10.1126/science.aav7271, ISSN 0036-8075, pages 88 - 91, XP055594948
OPPOSITION- Jonathan Strecker, Alim Ladha, Zachary Gardner, Jonathan L. Schmid-Burgk, Kira S. Makarova, Eugene V. Koonin, Feng Zhang, "RNA-guided DNA insertion with CRISPR-associated transposases", Science, US , (20190705), vol. 365, no. 6448, doi:10.1126/science.aax9181, ISSN 0036-8075, pages 48 - 53, XP055627601
OPPOSITION- Tong Baisong, Dong Huina, Cui Yali, Jiang Pingtao, Jin Zhaoxia, Zhang Dawei, "The Versatile Type V CRISPR Effectors and Their Application Prospects", Frontiers in Cell and Developmental Biology, CH , (20210101), vol. 8, doi:10.3389/fcell.2020.622103, ISSN 2296-634X, pages 1 - 11, XP093249217
OPPOSITION- Tautvydas Karvelis, Giedrius Gasiunas, Algirdas Miksys, Rodolphe Barrangou, Philippe Horvath, Virginijus Siksnys, "crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus", RNA BIOLOGY, (20130501), vol. 10, no. 5, doi:10.4161/rna.24203, ISSN 1547-6286, pages 841 - 851, XP055539891
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SEARCH- LIU LIANG ET AL, "Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities", CELL, ELSEVIER, AMSTERDAM, NL, (20170112), vol. 168, no. 1, doi:10.1016/J.CELL.2016.12.031, ISSN 0092-8674, page 121, XP029882149 [T] * the whole document *
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SEARCH- LIU LIANG ET AL, "C2c1-sgRNA Complex Structure Reveals RNA-Guided DNA Cleavage Mechanism", MOLECULAR CELL, (20170112), vol. 65, no. 2, doi:10.1016/J.MOLCEL.2016.11.040, ISSN 1097-2765, pages 310 - 322, XP029890333 [T] * the whole document *

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