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New Gadolinium Chelate Compounds For Use In Magnetic Resonance Imaging - EP3611169

The patent EP3611169 was granted to Bayer on Jul 21, 2021. The application was originally filed on May 30, 2016 under application number EP19194723A. The patent is currently recorded with a legal status of "Opposition Rejected".

EP3611169

BAYER
Application Number
EP19194723A
Filing Date
May 30, 2016
Status
Opposition Rejected
Jun 13, 2025
Grant Date
Jul 21, 2021
External Links
Slate, Register, Google Patents

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DE SIMONE & PARTNERSApr 20, 2022PACE NAPOLEONEADMISSIBLE

Patent Citations (25) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONEP0836485
DESCRIPTIONEP1931673
DESCRIPTIONEP2457914
DESCRIPTIONUS2007202047
DESCRIPTIONUS5560903
DESCRIPTIONUS5650133
DESCRIPTIONUS5679810
DESCRIPTIONUS5866562
DESCRIPTIONWO0151095
DESCRIPTIONWO2006136460
DESCRIPTIONWO9531444
DESCRIPTIONWO9732862
OPPOSITIONCA2274132
OPPOSITIONDE19652386
OPPOSITIONEP2457594
OPPOSITIONUS2002052354
OPPOSITIONUS2007202407
OPPOSITIONUS7294615
OPPOSITIONWO0151095
OPPOSITIONWO2006002873
OPPOSITIONWO2012059576
OPPOSITIONWO2014124943
OPPOSITIONWO9732862
SEARCHUS2007202047
SEARCHWO9732862

Non-Patent Literature (NPL) Citations (41) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- AIME S, J Magn Reson Imaging., (20090000), vol. 30, pages 1259 - 1267-
DESCRIPTION- BECKER S., Nephron Clin Pract., (20120000), vol. 121, pages c91 - c94-
DESCRIPTION- C.A. MONTALBETTIV. FALQUE, Tetrahedron, (20050000), vol. 61, pages 10827 - 10852-
DESCRIPTION- CARAVAN P., Chem. Soc. Rev., (20060000), vol. 35, pages 512 - 523-
DESCRIPTION- CHEMICAL ABSTRACTS, Database accession no. 1417898-94-2, page 369-
DESCRIPTION- CONG LI et al., J. Am.Chem.Soc., (20060000), vol. 128, pages 15072 - 15073-
DESCRIPTION- "European Collection of Cell Cultures", Cancer Res, (19900000), vol. 50, pages 138 - 141-
DESCRIPTION- FRENZEL T., Invest Radiol., (20080000), vol. 43, pages 817 - 828-
DESCRIPTION- GALIBERT et al., Biorg. and Med. Chem. Letters, (20100000), vol. 20, pages 5422 - 5425-
DESCRIPTION- GIESEL FL., Eur Radiol, (20100000), vol. 20, pages 2461 - 2474-
DESCRIPTION- H.C.J. OTTENHEIM et al., Tetrahedron, (19880000), vol. 44, pages 5583 - 5595-
DESCRIPTION- HELM L., Future Med Chem., (20100000), vol. 2, pages 385 - 396-
DESCRIPTION- HERMANN P., Dalton Trans., (20080000), pages 3027 - 3047-
DESCRIPTION- JACQUES V., Invest Radiol., (20100000), vol. 45, pages 613 - 624-
DESCRIPTION- J Neurosurg, (19710000), vol. 34, page 335-
DESCRIPTION- J. Org. Chem., (19960000), vol. 61, pages 8897 - 8903-
DESCRIPTION- LAURENT S. et al., Invest. Radiol., (20010000), vol. 36, no. 2, pages 115 - 122-
DESCRIPTION- MERBACH A.S., The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging, (20130000), ISBN 978-1-119-99176-2, pages 157 - 208-
DESCRIPTION- M. GALIBERT et al., Bioorg. Med. Chem. Letters, (20100000), vol. 20, pages 5422 - 5425-
DESCRIPTION- M. SUCHY et al., Org. Biomol. Chem., (20100000), vol. 8, pages 2560 - 2566-
DESCRIPTION- Pure Appl Chem, (19760000), vol. 45, pages 11 - 30-
DESCRIPTION- RANGANATHAN R.S., Investigative Radiology, (19980000), vol. 33, pages 779 - 797-
DESCRIPTION- ROHRER, Invest. Radiol., (20050000), vol. 40, no. 11, pages 715 - 724-
DESCRIPTION- Tetrahedron Letters, (20050000), vol. 46, pages 5577 - 5580-
DESCRIPTION- TOMBACH B, Eur Radiol, (20020000), vol. 12, no. 6, pages 1550 - 1556-
DESCRIPTION- WANG Y., Radiology, (20110000), vol. 260, pages 105 - 111-
DESCRIPTION- W. HAYES et al., Tetrahedron, (20030000), vol. 59, pages 7983 - 7996-
DESCRIPTION- YANG L, Radiology, (20120000), vol. 265, pages 248 - 253-
DESCRIPTION- S. M. BERGE, "Pharmaceutical Salts", J. Pharm. Sci., (19770000), vol. 66, doi:doi:10.1002/jps.2600660104, pages 1 - 19, XP002675560
OPPOSITION- "1, 3-Propanediamine, 2, 2-bis (amin0methyl) - (CA INDEX NAME)", Registry, Database accession no. 4742-00-1, URL: STN, XP055919925-
OPPOSITION- "1, 4, 7, 10-Tetraazacyclododecane (CA INDEX NAME)", Registry, (19841116), Database accession no. 294-90-6, URL: STN, XP055919920-
OPPOSITION- LIVRAMENTO et al., "A benzene-core trinuclear GdIII complex: towards the optimization of relaxivity for MRI contrast agent applications at high magnetic field", Dalton transactions, (20080000), pages 1195 - 1202, XP055919782-
OPPOSITION- MIÉVILLE et al., "Synthesis, complexation and NMR relaxation properties of Gd3+ complexes of Mes(Do3A)3", Dalton trans., (20110000), vol. 40, pages 4260 - 4267, XP055919790-
OPPOSITION- Zhaoda Zhang; Greenfield Matthew T; Spiller Marga; Mcmurry Thomas J; Lauffer Randall B; Caravan Peter, "Multilocus Binding Increases the Relaxivity of Protein-Bound MRI Contrast Agents", Angew. Chem., (20050000), vol. 44, pages 6766 - 6769, XP055067211
OPPOSITION- DI GREGORIO et al., "Gd loading by hypotonic swelling: an efficient and safe route for cellular labeling : GD-LOADING BY HYPOTONIC SWELLING", Contrast Media and Molecular Imaging, (20130000), vol. 8, no. 6, pages 475 - 486, XP055754903
OPPOSITION- Morcos; S K, "Extracellular gadolinium contrast agents: Differences in stability", European Journal of Radiology, (20080501), vol. 66, no. 2, pages 175 - 179, XP022635183
OPPOSITION- Hayes W; Osborn H M I; Osborne S D; Rastall R A; Romagnoli B, "One-pot synthesis of multivalent arrays of mannose mono- and disaccharides", Tetrahedron, (20030000), vol. 59, pages 7983 - 7996, XP004458547
OPPOSITION- FICHER et al., "Chemical aspects of peptide bond isomerisation", Chem. Soc. Rev., (20000000), vol. 29, no. 2, pages 119 - 127, XP055919771
OPPOSITION- Peter Caravan, "Strategies for increasing the sensitivity of gadolinium based MRI contrast agents", Chemical Society Reviews, (20060000), vol. 35, pages 512 - 523, XP008152996
OPPOSITION- SUCHY et al., "A paramagnetic chemical exchange-based MRI probe metabolized by cathepsin D: design, synthesis and cellular uptake studies", Org. Biomol. Chem., (20100326), vol. 8, no. 11, pages 2560 - 2566, XP055754680
OPPOSITION- Bumb Ambika; Brechbiel Martin W; Choyke Peter, "Macromolecular and dendrimer-based magnetic resonance contrast agents", Acta Radiol, (20100000), vol. 51, no. 7, pages 751 - 767, XP008149214

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