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| OPPOSITION | - Anonymous, "Innovative Chemicals for Process Intensification in Cell Culture Media - Process guidance for the use of the modified amino acids Phospho-Tyrosine Disodium Salt EMPROVE ® EXPERT and Sulfo-Cysteine Sodium Salt Sesquihydrate EMPROVE ® EXPERT in fed-batch processes (Technical Brief)", MERCK, MERCK, URL: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/779/536/innovative-chemicals-cellculturemedia-techbrief-tb2564en-mk.pdf, XP093251354 | - |
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| OPPOSITION | - David Brühlmann, Martin Jordan, Jürgen Hemberger, Markus Sauer, Matthieu Stettler, Hervé Broly, "Tailoring recombinant protein quality by rational media design", Biotechnology Progress, American Chemical Society, Hoboken, USA, Hoboken, USA, (20150529), vol. 31, no. 3, doi:10.1002/btpr.2089, ISSN 8756-7938, pages 615 - 629, XP055317367 | |
| OPPOSITION | - Rathore Anurag S., Kumar Singh Sumit, Pathak Mili, Read Erik K., Brorson Kurt A., Agarabi Cyrus D., Khan Mansoor, "Fermentanomics: Relating quality attributes of a monoclonal antibody to cell culture process variables and raw materials using multivariate data analysis", Biotechnology Progress, American Chemical Society, Hoboken, USA, Hoboken, USA, (20151101), vol. 31, no. 6, doi:10.1002/btpr.2155, ISSN 8756-7938, pages 1586 - 1599, XP055893072 | |
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| OPPOSITION | - Dawn M. Ecker, Thomas C. Ransohoff, "Mammalian cell culture capacity for biopharmaceutical manufacturing", Adv Biochem Eng Biotechnol, doi:10.1007/10_2013_215, pages 185 - 225, XP055728942 | |
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| OPPOSITION | - Moran Enda, Gammell Patrick, "Lifecycle Management for Recombinant Protein Production Using Mammalian Cell Culture Technology", Advances in biochemical engineering, biotechnology, Germany, Springer Berlin / Heidelberg, (20140101), vol. 139, pages 245 - 256, doi:10.1007/10_2013_258, ISSN 0724-6145, ISBN 364254049X, XP009560934 | |
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| OPPOSITION | - Reinhart David; Damjanovic Lukas; Kaisermayer Christian; Kunert Renate, "Benchmarking of commercially available CHO cell culture media for antibody production", Applied Microbiology and Biotechnology, Springer Berlin Heidelberg, Berlin/Heidelberg, Berlin/Heidelberg, (20150407), vol. 99, no. 11, doi:10.1007/s00253-015-6514-4, ISSN 0175-7598, pages 4645 - 4657, XP035502970 | |
| OPPOSITION | - Pan Xiao; Dalm Ciska; Wijffels René H.; Martens Dirk E., "Metabolic characterization of a CHO cell size increase phase in fed-batch cultures", Applied Microbiology and Biotechnology, Springer Berlin Heidelberg, Berlin/Heidelberg, Berlin/Heidelberg, (20170926), vol. 101, no. 22, doi:10.1007/s00253-017-8531-y, ISSN 0175-7598, pages 8101 - 8113, XP036347969 | |
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| OPPOSITION | - Zimmer Aline; Mueller Ronja; Wehsling Maria; Schnellbaecher Alisa; von Hagen Joerg, "Improvement and simplification of fed-batch bioprocesses with a highly soluble phosphotyrosine sodium salt", Journal of Biotechnology, Elsevier, Amsterdam NL, Amsterdam NL , (20140709), vol. 186, doi:10.1016/j.jbiotec.2014.06.026, ISSN 0168-1656, pages 110 - 118, XP029075451 | |
| OPPOSITION | - Hecklau Caroline; Pering Sascha; Seibel Ronja; Schnellbaecher Alisa; Wehsling Maria; Eichhorn Thomas; Hagen Joerg von; Zimmer Aline, "S-Sulfocysteine simplifies fed-batch processes and increases the CHO specific productivity via anti-oxidant activity", Journal of Biotechnology, Elsevier, Amsterdam NL, Amsterdam NL , (20151202), vol. 218, doi:10.1016/j.jbiotec.2015.11.022, ISSN 0168-1656, pages 53 - 63, XP029379422 | |
| OPPOSITION | - Ushijima Tomokazu, Matsusaka Hiroaki, Jikuya Hiroyuki, Ogawa Masahiro, Satoh Hikaru, Kumamaru Toshihiro, "Genetic analysis of cysteine-poor prolamin polypeptides reduced in the endosperm of the rice esp1 mutant", PLANT SCIENCE, Elsevier Ireland Ltd, IE, IE , (20110801), vol. 181, no. 2, doi:10.1016/j.plantsci.2011.04.011, ISSN 0168-9452, pages 125 - 131, XP093251358 | |
| OPPOSITION | - Ying Jing; Michael Borys; Samiksha Nayak; Susan Egan; Yueming Qian; Shih-Hsie Pan; Zheng Jian Li;, "Identification of cell culture conditions to control protein aggregation of IgG fusion proteins expressed in Chinese hamster ovary cells", Process Biochemistry, Elsevier Ltd, GB, GB , (20111010), vol. 47, no. 1, doi:10.1016/j.procbio.2011.10.009, ISSN 1359-5113, pages 69 - 75, XP028342261 | |
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| OPPOSITION | - Fatemeh Torkashvand, Behrouz Vaziri, Shayan Maleknia, Amir Heydari, Manouchehr Vossoughi, Fatemeh Davami, Fereidoun Mahboudi, Matthias Schnell, "Designed Amino Acid Feed in Improvement of Production and Quality Targets of a Therapeutic Monoclonal Antibody", PLOS ONE, Public Library of Science, (20151019), vol. 10, no. 10, doi:10.1371/journal.pone.0140597, page e0140597, XP055704734 | |
| OPPOSITION | - Thoring Lena, Wüstenhagen Doreen A., Borowiak Maria, Stech Marlitt, Sonnabend Andrei, Kubick Stefan, "Cell-Free Systems Based on CHO Cell Lysates: Optimization Strategies, Synthesis of “Difficult-to-Express” Proteins and Future Perspectives", PLOS ONE, (20160929), vol. 11, no. 9, doi:10.1371/journal.pone.0163670, page e0163670, XP093023719 | |
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