IP Verse

Interleukin-31 Monoclonal Antibody - EP3653645

The patent EP3653645 was granted to Zoetis Services on Aug 21, 2024. The application was originally filed on Jul 5, 2012 under application number EP19196963A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3653645

ZOETIS SERVICES
Application Number
EP19196963A
Filing Date
Jul 5, 2012
Status
Granted And Under Opposition
Jul 19, 2024
Grant Date
Aug 21, 2024
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions (2)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

MARGARET DIXONMay 21, 2025MEWBURN ELLISADMISSIBLE
BOEHRINGER INGELHEIM VETMEDICAMay 20, 2025D YOUNGADMISSIBLE

Patent Citations (38) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS2003031671
DESCRIPTIONUS5350576
DESCRIPTIONUS6194167
DESCRIPTIONUS6680053
DESCRIPTIONUS6774107
DESCRIPTIONUS6790639
EXAMINATIONUS2006141579
EXAMINATIONUS2007160611
EXAMINATIONUS7939068
OPPOSITIONEP1270595
OPPOSITIONEP1671642
OPPOSITIONEP2644698
OPPOSITIONEP2734549
OPPOSITIONEP2829551
OPPOSITIONEP3842456
OPPOSITIONUS2003224487
OPPOSITIONUS2006141579
OPPOSITIONUS2007160610
OPPOSITIONUS2009208494
OPPOSITIONUS2009220417
OPPOSITIONUS2009252732
OPPOSITIONUS2010061988
OPPOSITIONUS2010075996
OPPOSITIONUS2011106528
OPPOSITIONUS7939068
OPPOSITIONUS8133899
OPPOSITIONWO03060080
OPPOSITIONWO2006088956
OPPOSITIONWO2006122079
OPPOSITIONWO2007143231
OPPOSITIONWO2011047262
OTHEREP2734539
OTHEREP2734549
OTHERWO03060080
SEARCHUS2009252732
SEARCHWO2006122079
SEARCHWO2007143231
SEARCHWO2011047262

Non-Patent Literature (NPL) Citations (109) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- BILSBOROUGH et al., J Allergy Clin Immunol., (20060000), vol. 117, no. 2, pages 418 - 25-
DESCRIPTION- BOWIE et al., Science, (19900000), vol. 247, pages 1306 - 10-
DESCRIPTION- CHATTOPADHYAY et al., J Biol Chem, (20070000), vol. 282, pages 3014 - 26-
DESCRIPTION- CHELIUS et al., Anal Chem., (20060000), vol. 78, no. 7, pages 2370 - 6-
DESCRIPTION- CHOTHIALESK, J. Mol. Biol., (19870000), vol. 196, pages 901 - 917-
DESCRIPTION- CUNNINGHAM et al., Science, (19890000), vol. 244, pages 1081 - 85-
DESCRIPTION- DE VOS et al., Science, (19920000), vol. 255, pages 306 - 12-
DESCRIPTION- DILLON et al., Nat Immunol, (20040000), vol. 5, pages 752 - 60-
DESCRIPTION- DNA Cloning, IRL Press, (19850000), vol. II, pages 45 - 66-
DESCRIPTION- "GenBank", Database accession no. AF198257.1-
DESCRIPTION- GORMAN et al., Proc. Natl. Acad. Sci., (19820000), vol. 79, pages 6777 - 329-
DESCRIPTION- GROSSCHEDL et al., Cell, (19850000), vol. 41, page 885-
DESCRIPTION- IZAKI, Jpn. J. Bacteriol., (19780000), vol. 33, pages 729 - 42-
DESCRIPTION- JOHN et al., Rev. Infect. Dis., (19860000), vol. 8, pages 693 - 704-
DESCRIPTION- JOHNSTON et al., Science, (19880000), vol. 240, page 1538-
DESCRIPTION- KABAT et al., Sequences of Proteins of Immunological Interest, Public Health Service, National Institutes of Health, (19910000), pages 647 - 669-
DESCRIPTION- KENDALL et al., J. Bacteriol., (19870000), vol. 169, pages 4177 - 83-
DESCRIPTION- LATHE et al., J. Molec. Biol., (19850000), vol. 183, pages 1 - 12-
DESCRIPTION- LE SAUX S et al., Biol Chem., (20100129), vol. 285, no. 5, pages 3470 - 7-
DESCRIPTION- MAEDA et al., J. Vet. Med. Sci., (20080000), vol. 70, pages 51 - 55-
DESCRIPTION- MAEDA et al., Vet. Immunol. Immunopathol., (20050000), vol. 103, pages 83 - 92-
DESCRIPTION- MARSELLAOLIVRY, Clinics in Dermatology, (20030000), vol. 21, pages 122 - 133-
DESCRIPTION- NEIS et al., J. Allergy Clin. Immunol., (20060000), vol. 118, pages 930 - 937-
DESCRIPTION- NUTTALL et al., Vet. Immunol. Immunopathol., (20020000), vol. 90, pages 145 - 154-
DESCRIPTION- OKAYAMA et al., Mol. Cell. Biol., (19830000), vol. 1-12, page 280-
DESCRIPTION- OLIVRY et al., "a genetically-predisposed inflammatory and pruritic allergic skin disease with characteristic clinical features", Veterinary Immunology and Immunopathology, (20010000), vol. 81, pages 143 - 146-
DESCRIPTION- PICCO et al., Vet Dermatol, (20080000), vol. 19, pages 150 - 155-
DESCRIPTION- PRELAUD et al., Revue de Medecine Veterinaire, (19980000), vol. 149, pages 1057 - 1064-
DESCRIPTION- RAAP et al., Exp Dermatol., (20100000), vol. 19, no. 5, pages 464 - 6-
DESCRIPTION- RAAP et al., J Allergy Clin Immunol., (20080000), vol. 122, no. 2, pages 421 - 3-
DESCRIPTION- RATTAN et al., Ann. NY Acad. Sci., (19920000), vol. 663, pages 48 - 62-
DESCRIPTION- SCHWARTZMAN et al., Clin. Exp. Immunol., (19710000), vol. 9, pages 549 - 569-
DESCRIPTION- SCOTT et al., Canadian Veterinary Journal, (20020000), vol. 43, pages 601 - 603-
DESCRIPTION- SEIFTER et al., Meth. Enzymol., (19900000), vol. 182, pages 626 - 46-
DESCRIPTION- SMITH et al., J. Mol. Biol., (19920000), vol. 224, pages 899 - 904-
DESCRIPTION- SONKOLY et al., J Allergy Clin Immunol, (20060000), vol. 117, pages 411 - 7-
DESCRIPTION- SOUSAMARSELLA, Veterinary Immunology and Immunopathology, (20010000), vol. 81, pages 153 - 157-
DESCRIPTION- TAKAOKA et al., Eur J. Pharmacol., (20050000), vol. 516, pages 180 - 181-
DESCRIPTION- TAKAOKA et al., Exp. Dermatol., (20060000), vol. 15, pages 161 - 167-
DESCRIPTION- WAHL et al., J. Nucl. Med., (19830000), vol. 24, pages 316 - 25-
DESCRIPTION- WAI et al., Immunology, (20070000), vol. 122, pages 532 - 541-
DESCRIPTION- WILLEMSE T., J small Anim Pract, (19860000), vol. 27, pages 771 - 778-
DESCRIPTION- YAGI, International Journal of Molecular Medicine, (20070000), vol. 19, no. 6, pages 941 - 946-
EXAMINATION- M. Debré ET AL, "Infusion of Fc gamma fragments for treatment of children with acute immune thrombocytopenic purpura.", The Lancet, AMSTERDAM, NL, (19931016), vol. 342, no. 8877, doi:10.1016/0140-6736(93)92000-J, ISSN 0140-6736, pages 945 - 949, XP055311761
OPPOSITION- Anonymous, "Interleukin 31 receptor A - IL31RA", UniProtKB, (20121031), Database accession no. F1PTZ6, XP093282620-
OPPOSITION- Anonymous, "Oncostatin M receptor", UniProtKB, (20190605), Database accession no. E2QWS7, XP093282623-
OPPOSITION- Baranska-Rybak W, Nowicki R, Grubska-Suchanek E, Sokolowska-Wojdylo M, Trzeciak M, Michajlowski I, Lugowska-Umer H, Sobjanek M, "Rola interleukiny 31 w swiadzie", PRZEGLAD DERMATOLOGICZNY., PL , (20080101), vol. 95, no. 6, ISSN 0033-2526, pages 571 - 573, XP009561347-
OPPOSITION- D33 - Board of Appeal preliminary opinion of 23 February 2022 (T 102/20)-
OPPOSITION- D34 - Minutes of the grandparent Appeal hearing (T 102/20)-
OPPOSITION- D35 - Annex A submitted by Opponent 2 in the Opposition to the grandparent patent on 23-02-2018-
OPPOSITION- D37 - Alignment IL-31 Dog vs Red Fox polypeptide sequence-
OPPOSITION- D40 - pSTAT Experimental Report-
OPPOSITION- D41 - Declaration of Prof. Kun-Liang Guan-
OPPOSITION- D42 - Declaration of Assistant Prof. Adam Rudinsky-
OPPOSITION- D43 - Declaration of Dr. Anthony Yu-
OPPOSITION- D56 - EP3219729 Board of Appeal preliminary opinion dated 10 April 2025 (T 709/23)-
OPPOSITION- D67a - CV of Dr. Peter Canning-
OPPOSITION- D67 - Declaration of Dr. Peter Canning-
OPPOSITION- D69 - Decision of the Board of Appeal T0102/20 - 3.3.04 of 15 March 2022 on EP2734549-
OPPOSITION- D70 - Minutes of the Oral Proceedings before the Board of Appeal in Appeal T0102/20 - 3.3.04 on EP2734549-
OPPOSITION- D71 - Preliminary opinion of the Board of Appeal in Decision T102/20 - 3.3.04 on EP2734549-
OPPOSITION- D72 - Declaration of Prof. Guan (“D41” from the opposition proceedings of EP2734549)-
OPPOSITION- D73 - Declaration of Prof. Yu (“D43” from the opposition proceedings of EP2734549)-
OPPOSITION- Geoff Spencer, "Analysis Sheds Light on Human Disease; Differences Among Canine Breeds", 2005 Release: Researchers Publish Dog Genome Sequence - National Human Genome Research Institute (NHGRI), (20051207), pages 1 - 2, URL: https://www.genome.gov/17515860/2005-release-researchers-publish-dog-genome-sequence/, (20180516), XP055475905-
OPPOSITION- HILL P B; LO A; EDEN C A N; HUNTLEY S; MOREY V; RAMSEY S; RICHARDSON C; SMITH D J; SUTTON C; TAYLOR M D; THORPE E; TIDMARSH R; WILLIAMS V, "SURVEY OF THE PREVALENCE, DIAGNOSIS AND TREATMENT OF DERMATOLOGICAL CONDITIONS IN SMALL ANIMALS IN GENERAL PRACTICE", Veterinary Record, BRITISH VETERINARY ASSOCIATION, LONDON, GB, GB , (20060422), vol. 158, no. 16, ISSN 0042-4900, pages 533 - 538, XP009076898-
OPPOSITION- Maeda, S. ; Tsukui, T. ; Saze, K.i. ; Masuda, K. ; Ohno, K. ; Tsujimoto, H. ; Iwabuchi, S., "Production of a monoclonal antibody to canine thymus and activation-regulated chemokine (TARC) and detection of TARC in lesional skin from dogs with atopic dermatitis", Veterinary Immunology and Immunopathology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (20050110), vol. 103, no. 1-2, ISSN 0165-2427, pages 83 - 92, XP027671865-
OPPOSITION- P. B. Hill,, J. Hoare, P. Lau-Gillard, J. Rybnicek, R. T. Mathie, "Pilot study of the effect of individualised homeopathy on the pruritus associated with atopic dermatitis in dogs", Vet Record, (20090321), pages 364 - 370, Vet Record, URL: http://veterinaryrecord.bmj.com/content/164/12/364, (20180518), XP055476910-
OPPOSITION- Takaoka, A. ; Arai, I. ; Sugimoto, M. ; Yamaguchi, A. ; Tanaka, M. ; Nakaike, S., "Expression of IL-31 gene transcripts in NC/Nga mice with atopic dermatitis", European Journal of Pharmacology, Elsevier science, NL, NL , (20050601), vol. 516, no. 2, ISSN 0014-2999, pages 180 - 181, XP027695383-
OPPOSITION- "UniProtKB-C7G0W1 (C7G0W1_CANLF)", UniProtKB, (20091013), Database accession no. C7G0W1, XP055476926-
OPPOSITION- Shizuo Akira, "Functional Roles of STAT Family Proteins: Lessons from Knockout Mice", Stem Cells, Wiley, (19990501), vol. 17, doi:10.1002/stem.170138 , ISSN 1066-5099, pages 138 - 146, XP055818928
OPPOSITION- M. Debré, Bonnet M C; Fridman W H; Carosella E; Philippe N; Reinert P; Vilmer E; Kaplan C; Teillaud J L; Griscelli C, "Infusion of Fc gamma fragments for treatment of children with acute immune thrombocytopenic purpura.", The Lancet, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (19931016), vol. 342, no. 8877, doi:10.1016/0140-6736(93)92000-J, pages 945 - 949, XP055311761
OPPOSITION- O'Kennedy, R. ; Byrne, M. ; O'Fagain, C. ; Berns, G., "Experimental section", Biochemical Education, Pergamon, (19900701), vol. 18, no. 3, doi:10.1016/0307-4412(90)90219-E, ISSN 0307-4412, pages 136 - 140, XP023338790
OPPOSITION- Qing Zhang, Prabhakar Putheti , Qiang Zhou , Quansheng Liu , Wenda Gao, "Author manuscript: Structures and biological functions of IL-31 and IL-31 receptors", Cytokine & Growth Factor Reviews, Elsevier Ltd, GB, GB , (20080101), vol. 19, no. 5-6, doi:10.1016/j.cytogfr.2008.08.003, ISSN 1359-6101, pages 1 - 18, XP055818934
OPPOSITION- Sonkoly, E. Muller, A. Lauerma, A.I. Pivarcsi, A. Soto, H. Kemeny, L. Alenius, H. Dieu-Nosjean, M.C. Meller, S. Rieker, J. Steinhoff, M. Hoffmann, T.K. Ruzicka, T. Zlotnik, A. Homey, B., "IL-31: A new link between T cells and pruritus in atopic skin inflammation", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20060201), vol. 117, no. 2, doi:10.1016/j.jaci.2005.10.033, ISSN 0091-6749, pages 411 - 417, XP005275427
OPPOSITION- Bilsborough, J. Leung, D.Y.M. Maurer, M. Howell, M. Boguniewcz, M. Yao, L. Storey, H. LeCiel, C. Harder, B. Gross, J.A., "IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20060207), vol. 117, no. 2, doi:10.1016/j.jaci.2005.10.046, ISSN 0091-6749, pages 418 - 425, XP005275428
OPPOSITION- Neis, M.M. Peters, B. Dreuw, A. Wenzel, J. Bieber, T. Mauch, C. Krieg, T. Stanzel, S. Heinrich, P.C. Merk, H.F. Bosio, A. Baron, J.M. Hermanns, H.M., "Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20061001), vol. 118, no. 4, doi:10.1016/j.jaci.2006.07.015, ISSN 0091-6749, pages 930 - 937, XP005685915
OPPOSITION- Raap, U. ; Wichmann, K. ; Bruder, M. ; Stander, S. ; Wedi, B. ; Kapp, A. ; Werfel, T., "Correlation of IL-31 serum levels with severity of atopic dermatitis", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20080801), vol. 122, no. 2, doi:10.1016/j.jaci.2008.05.047, ISSN 0091-6749, pages 421 - 423, XP023518360
OPPOSITION- Mizuno, T. ; Kanbayashi, S. ; Okawa, T. ; Maeda, S. ; Okuda, M., "Molecular cloning of canine interleukin-31 and its expression in various tissues", Veterinary Immunology and Immunopathology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (20090915), vol. 131, no. 1-2, doi:10.1016/j.vetimm.2009.03.014, ISSN 0165-2427, pages 140 - 143, XP026469356
OPPOSITION- Hillier Andrew, Griffin Craig E, "The ACVD task force on canine atopic dermatitis (I): incidence and prevalence", Veterinary Immunology and Immunopathology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (20010901), vol. 81, no. 3-4, doi:10.1016/S0165-2427(01)00296-3, ISSN 0165-2427, pages 147 - 151, XP093282606
OPPOSITION- RIECHMANN L, ET AL., "RESHAPING HUMAN ANTIBODIES FOR THERAPY", Nature, (19880324), vol. 332, doi:10.1038/332323a0, pages 323 - 327, XP002949268
OPPOSITION- Rosanna Marsella, Giampiero Girolomoni, "Canine Models of Atopic Dermatitis: A Useful Tool with Untapped Potential", Journal of Investigative Dermatology, Elsevier, (20091001), vol. 129, no. 10, doi:10.1038/jid.2009.98, ISSN 0022-202X, pages 2351 - 2357, XP055476901
OPPOSITION- Cevikbas, X Wang, S Seeliger, M Fischer, SR Dillon, B Homey, A Basbaum, M Steinhoff, "700 Interleukin-31 directly regulates neuronal function in inflammation and itch", Journal of Investigative Dermatology, Elsevier, (20100501), vol. 130, no. Suppl. 1, doi:10.1038/jid.2010.71, ISSN 0022-202X, page S117, XP055475887
OPPOSITION- DILLON STACEY R ET AL, "Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice.", Nature Immulogy, Nature Publishing Group US, New York, New York , (20040701), vol. 5, no. 7, doi:10.1038/ni1084, ISSN 1529-2908, pages 752 - 760, XP002353112
OPPOSITION- LE SAUX S, ET AL, "MOLECULAR DISSECTION OF HUMAN INTERLEUKIN-31-MEDIATED SIGNAL TRANSDUCTION THROUGH SITE-DIRECTED MUTAGENESIS", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (20091117), vol. 285, no. 5, doi:10.1074/JBC.M109.049189, ISSN 0021-9258, pages 3470 - 3477, XP003035910
OPPOSITION- Im Myung, Lee Sang Sin, Lee Young, Kim Chang Deok, Seo Young Joon, Lee Jeung Hoon, Park Jang Kyu, "Prognostic factors in methylprednisolone pulse therapy for alopecia areata : Pulse therapy for alopecia areata", Journal of dermatology, JAPANESE DERMATOLOGICAL ASSOCIATION, TOKYO., JP, JP , (20110801), vol. 38, no. 8, doi:10.1111/j.1346-8138.2010.01135.x, ISSN 0385-2407, pages 767 - 772, XP093282600
OPPOSITION- Carr Melissa N., Torres Sheila M. F., Koch Sandra N., Reiter Lisa V., "Investigation of the pruritogenic effects of histamine, serotonin, tryptase, substance P and interleukin‐2 in healthy dogs", VETERINARY DERMATOLOGY., PERGAMON PRESS., GB, GB , (20090401), vol. 20, no. 2, doi:10.1111/j.1365-3164.2008.00716.x, ISSN 0959-4493, pages 105 - 110, XP093282656
OPPOSITION- Thierry Olivry, Deboer Douglas J., Favrot Claude, Jackson Hilary A., Mueller Ralf S., Nuttall Tim, Prélaud Pascal, "Treatment of canine atopic dermatitis: 2010 clinical practice guidelines from the International Task Force on Canine Atopic Dermatitis", VETERINARY DERMATOLOGY., PERGAMON PRESS., GB, GB , (20100601), vol. 21, no. 3, doi:10.1111/j.1365-3164.2010.00889.x, ISSN 0959-4493, pages 233 - 248, XP055640306
OPPOSITION- Andrea J. Gonzales, William R. Humphrey, James E. Messamore, Timothy J. Fleck, Gregory J. Fici, John A. Shelly, Janet F. Teel, Gary F. Bammert, Steven A. Dunham, Troy E. Fuller, Robert B. Mccall, "Interleukin-31: its role in canine pruritus and naturally occurring canine atopic dermatitis", VETERINARY DERMATOLOGY., PERGAMON PRESS., GB, GB , (20130219), vol. 24, no. 1, doi:10.1111/j.1365-3164.2012.01098.x, ISSN 0959-4493, pages 48 - e12, XP055284818
OPPOSITION- J. Buddenkotte; M. Steinhoff, "Pathophysiology and therapy of pruritus in allergic and atopic diseases", ALLERGY, Wiley-Blackwell Publishing Ltd., United Kingdom, United Kingdom , (20100407), vol. 65, no. 7, doi:10.1111/j.1398-9995.2010.01995.x, ISSN 0105-4538, pages 805 - 821, XP071461035
OPPOSITION- A. Takaoka; I. Arai; M. Sugimoto; Y. Honma; N. Futaki; A. Nakamura; S. Nakaike, "Involvement of IL‐31 on scratching behavior in NC/Nga mice with atopic‐like dermatitis", EXPERIMENTAL DERMATOLOGY, BLACKWELL MUNSGAARD, COPENHAGEN; DK, COPENHAGEN; DK , (20060215), vol. 15, no. 3, doi:10.1111/j.1600-0625.2006.00405.x, ISSN 0906-6705, pages 161 - 167, XP071775864
OPPOSITION- Øystein Grimstad; Yasushi Sawanobori; Christian Vestergaard; Janine Bilsborough; Uffe Bang Olsen; Christian Grønhøj‐Larsen; Kouji Matsushima, "Anti‐interleukin‐31‐antibodies ameliorate scratching behaviour in NC/Nga mice: a model of atopic dermatitis", EXPERIMENTAL DERMATOLOGY, BLACKWELL MUNSGAARD, COPENHAGEN; DK, COPENHAGEN; DK , (20081024), vol. 18, no. 1, doi:10.1111/j.1600-0625.2008.00766.x, ISSN 0906-6705, pages 35 - 43, XP071776299
OPPOSITION- David S. Aaronson, Curt M. Horvath, "A Road Map for Those Who Don't Know JAK-STAT", Science - Author Manuscript, American Association for the Advancement of Science, US, US , (20020531), vol. 296, no. 5573, doi:10.1126/science.1071545 , ISSN 0036-8075, pages 1653 - 1655, XP055476912
OPPOSITION- Dambacher J., Beigel F., Seiderer J., Haller D., Goke B., Auernhammer C. J, Brand S., "Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease", Gut microbiota, British medical association , London, UK, UK , vol. 56, no. 9, doi:10.1136/gut.2006.118679, ISSN 0017-5749, pages 1257 - 1265, XP093183140
OPPOSITION- Song Lanxi, Rawal Bhupendra, Nemeth Jeffrey A., Haura Eric B., "JAK1 Activates STAT3 Activity in Non-Small-Cell Lung Cancer Cells and IL-6 Neutralizing Antibodies Can Suppress JAK1-STAT3 Signaling", Molecular Cancer Therapeutics, American Association for Cancer Research, US, US , (20110301), vol. 10, no. 3, doi:10.1158/1535-7163.MCT-10-0502, ISSN 1535-7163, pages 481 - 494, XP055821750
OPPOSITION- Pj Felsburg, "Overview of immune system development in the dog: comparison with humans", HUMAN AND EXPERIMENTAL TOXICOLOGY., MCMILLAN, BASINGSTOKE., GB, GB , (20020101), vol. 21, doi:10.1191/0960327102ht286oa, ISSN 0960-3271, pages 487 - 492, XP055475908
OPPOSITION- Gfl Hofbauer, S Nobbe, P Dziunycz, B Mühleisen, J Bilsborough, Sr Dillon, Le French, "IL-31 Expression by Inflammatory Cells is Preferentially Elevated in Atopic Dermatitis", Acta Dermato-Venereologica, Society for the Publication of Acta Dermato-Venereologica, (20120101), vol. 92, no. 1, doi:10.2340/00015555-1191, ISSN 00015555, pages 24 - 28, XP055142727
OTHER- Andrew Hilliera, Griffin Craig E, "The ACVD task force on canine a topic dermatitis (I): incidence and prevalence", Veterinary Immunology and Immunopathology, ELSEVIER, (20010101), vol. 81, pages 147 - 151, XP055475864-
OTHER- Anonymous , "Interleukin 31", UniProtKB, (20091013), Database accession no. C7GOE1, URL: UniProt, XP055959635-
OTHER- Zhang, Q. ; Putheti, P. ; Zhou, Q. ; Liu, Q. ; Gao, W., "Structures and biological functions of IL-31 and IL-31 receptors", Cytokine & Growth Factor Reviews, Elsevier Ltd, GB, GB , (20081001), vol. 19, no. 5-6, doi:10.1016/j.cytogfr.2008.08.003, ISSN 1359-6101, pages 347 - 356, XP025714385
SEARCH- MAEDA S ET AL, "Production of a monoclonal antibody to canine thymus and activation-regulated chemokine (TARC) and detection of TARC in lesional skin from dogs with atopic dermatitis", VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, ELSEVIER BV, AMSTERDAM, NL, vol. 103, no. 1-2, ISSN 0165-2427, (20050110), pages 83 - 92, (20050110), XP027671865 [A] 1-15 * the whole document *-
SEARCH- TAKAOKA A ET AL, "Expression of IL-31 gene transcripts in NC/Nga mice with atopic dermatitis", EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE, NL, vol. 516, no. 2, ISSN 0014-2999, (20050601), pages 180 - 181, (20050601), XP027695383 [A] 1-15 * the whole document *-
SEARCH- SONKOLY ET AL, "IL-31: A new link between T cells and pruritus in atopic skin inflammation", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ELSEVIER, AMSTERDAM, NL, (20060201), vol. 117, no. 2, doi:10.1016/J.JACI.2005.10.033, ISSN 0091-6749, pages 411 - 417, XP005275427 [A] 1-15 * the whole document *
SEARCH- BILSBOROUGH ET AL, "IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ELSEVIER, AMSTERDAM, NL, (20060207), vol. 117, no. 2, doi:10.1016/J.JACI.2005.10.046, ISSN 0091-6749, pages 418 - 425, XP005275428 [A] 1-15 * the whole document *
SEARCH- NEIS ET AL, "Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ELSEVIER, AMSTERDAM, NL, (20061001), vol. 118, no. 4, doi:10.1016/J.JACI.2006.07.015, ISSN 0091-6749, pages 930 - 937, XP005685915 [A] 1-15 * the whole document *
SEARCH- MIZUNO T ET AL, "Molecular cloning of canine interleukin-31 and its expression in various tissues", VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, ELSEVIER BV, AMSTERDAM, NL, vol. 131, no. 1-2, doi:10.1016/J.VETIMM.2009.03.014, ISSN 0165-2427, (20090915), pages 140 - 143, (20090331), XP026469356 [I] 5-11,15 * the whole document *
SEARCH- DILLON S R ET AL, "Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice", NATURE IMMUNOLOGY, NATURE PUBLISHING GROUP US, NEW YORK, (20040606), vol. 5, no. 7, doi:10.1038/NI1084, ISSN 1529-2908, pages 752 - 760, XP002407998 [A] 1-15 * the whole document *
SEARCH- LE SAUX S ET AL, "MOLECULAR DISSECTION OF HUMAN INTERLEUKIN-31-MEDIATED SIGNAL TRANSDUCTION THROUGH SITE-DIRECTED MUTAGENESIS", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, (20091117), vol. 285, no. 5, doi:10.1074/JBC.M109.049189, ISSN 0021-9258, pages 3470 - 3477, XP003035910 [A] 1-15 * the whole document *
SEARCH- TAKAOKA A ET AL, "Involvement of IL-31 on scratching behavior in NC/Nga mice with atopic-like dermatitis", EXPERIMENTAL DERMATOLOGY, BLACKWELL MUNSGAARD, COPENHAGEN; DK, (20060301), vol. 15, no. 3, doi:10.1111/J.1600-0625.2006.00405.X, ISSN 0906-6705, pages 161 - 167, XP002401005 [A] 1-15 * the whole document *
SEARCH- ?YSTEIN GRIMSTAD ET AL, "Anti-interleukin-31-antibodies ameliorate scratching behaviour in NC/Nga mice: a model of atopic dermatitis", EXPERIMENTAL DERMATOLOGY, (20090101), vol. 18, no. 1, doi:10.1111/j.1600-0625.2008.00766.x, ISSN 0906-6705, pages 35 - 43, XP055001458 [A] 1-15 * the whole document *

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents