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| OPPOSITION | - Feng et al., "Supporting Information to: Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk", Proceedings of the National Academy of Sciences, (20150217), pages 1 - 8, XP055941122 |
| OPPOSITION | - Feng Mingye, Chen James Y., Weissman-Tsukamoto Rachel, Volkmer Jens-Peter, Ho Po Yi, Mckenna Kelly M., Cheshier Samuel, Zhang Michael, Guo Nan, Gip Phung, Mitra Siddhartha S., Weissman Irving L., "Supporting Information to: Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk", Proceedings of the National Academy of Sciences, (20150217), pages 1 - 8, XP055941122 |
| OPPOSITION | - Nika Cyrus, "The role of tumor-associated macrophages in human skin cancer.", Thesis Yale University, (20130101), URL: https://elischolar.library.yale.edu/cgi/viewcontent.cgi?article=1784&context=ymtdl, XP002782999 |
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| OPPOSITION | - Tseng et al., "Supporting Information to: Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response", Proceedings of the National Academy of Sciences, (20130702), pages 1 - 6, XP055941170 |
| OPPOSITION | - MAJETI, R. et al., "CD 47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells", Cell, (20090000), vol. 138, doi:10.1016/j.cell.2009.05.045, pages 286 - 299, XP055277135 |
| OPPOSITION | - Chao et al., "The CD47-SIRPa; pathway in cancer immune evasion and potential therapeutic implications", Current Opinion in Immunology, (20120401), vol. 24, no. 2, doi:10.1016/j.coi.2012.01.010, ISSN 09527915, pages 225 - 232, XP055029985 |
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| OPPOSITION | - Fang Ma et al., "The TLR7 agonists imiquimod and gardiquimod improve DC-based immunotherapy for melanoma in mice", Cellular & Molecular Immunology, London, (20100901), vol. 7, no. 5, doi:10.1038/cmi.2010.30, ISSN 1672-7681, pages 381 - 388, XP055371598 |
| OPPOSITION | - Brown Guy C., Jonas J. Neher, "Microglial phagocytosis of live neurons", Nature Reviews, Neuroscience, (20140401), vol. 15, no. 4, doi:10.1038/nrn3710, pages 209 - 216, XP055941470 |
| OPPOSITION | - Redelman-Sidi Gil, Glickman Michael S., Bochner Bernard H., "The mechanism of action of BCG therapy for bladder cancer — a current perspective", Nature reviews. Urology, US , (20140301), vol. 11, no. 3, doi:10.1038/nrurol.2014.15, ISSN 1759-4812, pages 153 - 162, XP055941485 |
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| OPPOSITION | - TSENG, D. et al., "Anti- CD 47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T- cell response", Proceedings of the National Academy of Sciences, (20130000), vol. 110, no. 27, doi:10.1073/pnas.1305569110, pages 11103 - 11108, XP055245737 |
| OPPOSITION | - Tseng et al., "Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response", Proceedings of the National Academy of Sciences, (20130702), vol. 110, no. 27, doi:10.1073/pnas.1305569110, ISSN 0027-8424, pages 11103 - 11108, XP055245737 |
| OPPOSITION | - Feng et al., "Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk", Proceedings of the National Academy of Sciences, (20150217), vol. 112, no. 7, doi:10.1073/pnas.1424907112, ISSN 0027-8424, pages 2145 - 2150, XP055470309 |
| OPPOSITION | - FENG, M. et al., "Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk", Proceedings of the National Academy of Sciences, (20150000), vol. 112, no. 7, doi:10.1073/pnas.1424907112, pages 2145 - 2150, XP055470309 |
| OPPOSITION | - Ogden Carol Anne, Decathelineau Aimee, Hoffmann Peter R., Bratton Donna, Ghebrehiwet Berhane, Fadok Valerie A., Henson Peter M., "C1q and Mannose Binding Lectin Engagement of Cell Surface Calreticulin and Cd91 Initiates Macropinocytosis and Uptake of Apoptotic Cells", Journal of Experimental Medicine,, US , (20010917), vol. 194, no. 6, doi:10.1084/jem.194.6.781, ISSN 0022-1007, pages 781 - 796, XP055941480 |
| OPPOSITION | - KONG, X-N. et al., "LPS-induced down-regulation of signal regulatory protein alpha contributes to innate immune activation in macrophages", Journal of Experimental Medicine, (20070000), vol. 204, no. 11, doi:10.1084/jem.20062611, pages 2719 - 2731, XP055456730 |
| OPPOSITION | - A. P. A. Theocharides, L. Jin, P.-Y. Cheng, T. K. Prasolava, A. V. Malko, J. M. Ho, A. G. Poeppl, N. Van Rooijen, M. D. Minden, J. S. Danska, J. E. Dick, J. C. Y. Wang, "Disruption of SIRPa; signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts", Blood, US , (20120924), vol. 119, no. 18, doi:10.1182/blood-2011-11-391367, ISSN 0006-4971, pages 1883 - 1899, XP055126663 |
| OPPOSITION | - Theocharides et al., "Disruption of SIRPa; signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts", Blood, US , (20120924), vol. 119, no. 18, doi:10.1182/blood-2011-11-391367, ISSN 0006-4971, pages 1883 - 1899, XP055126663 |
| OPPOSITION | - "Workshop Sessions", Immunology, GB , (20120912), vol. 137, doi:10.1111/imm.12001, ISSN 0019-2805, pages 1 - 184, XP071276260 |
| OPPOSITION | - K. Weiskopf et al., "Supplementary Materials for: Engineered SIRPa variants as immunotherapeutic adjuvants to anti-cancer antibodies", Science, US , (20130705), doi:10.1126/science.1238856, ISSN 0036-8075, pages 1 - 36, XP055488633 |
| OPPOSITION | - Weiskopf et al., "Engineered SIRP Variants as Immunotherapeutic Adjuvants to Anticancer Antibodies", Science, US , (20130705), vol. 341, no. 6141, doi:10.1126/science.1238856, ISSN 0036-8075, pages 88 - 91, XP055223925 |
| OPPOSITION | - WEISKOPF K. et al., "Engineered SIRP Variants as Immunotherapeutic Adjuvants to Anticancer Antibodies", Science, (20130000), vol. 341, no. 6141, doi:10.1126/science.1238856, pages 88 - 91, XP055223925 |
| OPPOSITION | - OKUSAWA, T. et al., "Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6", Infection and Immunity, (20040000), vol. 72, no. 3, doi:10.1128/IAI.72.3.1657-1665.2004, pages 1657 - 1665, XP002468539 |
| OPPOSITION | - Guiducci et al., "Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection", Cancer research, US , (20050331), vol. 65, no. 8, doi:10.1158/0008-5472.CAN-04-4262, ISSN 0008-5472, pages 3437 - 3446, XP009510468 |
| OPPOSITION | - CHAO, M. P. et al., "Therapeutic Antibody Targeting of CD 47 Eliminates Human Acute Lymphoblastic Leukemia", Cancer Research, (20110000), vol. 71, no. 4, doi:10.1158/0008-5472.CAN-10-2238, pages 1374 - 1384, XP055029988 |
| OPPOSITION | - Lu et al., "Polysaccharide Krestin Is a Novel TLR2 Agonist that Mediates Inhibition of Tumor Growth via Stimulation of CD8 T Cells and NK Cells", Clinical Cancer Research, US, (20110101), vol. 17, no. 1, doi:10.1158/1078-0432.CCR-10-1763, ISSN 1078-0432, pages 67 - 76, XP055941460 |
| OPPOSITION | - ADAMS. S. et al., "Topical TLR7 Agonist Imiquimod Can Induce Immune-Mediated Rejection of Skin Metastases in Patients with Breast Cancer", Clinical Cancer Research, (20120000), vol. 18, no. 24, doi:10.1158/1078-0432.CCR-12-1149, pages 6748 - 6757, XP055185098 |
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| OPPOSITION | - BYRNE, J. C. et al., "Bruton's Tyrosine Kinase Is Required for Apoptotic Cell Uptake via Regulating the Phosphorylation and Localization of Calreticulin", Journal of Immunology, (20130000), vol. 190, no. 10, doi:10.4049/jimmunol.1300057, pages 5207 - 5215, XP002782998 |
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| SEARCH | - MARK P CHAO ET AL, "The CD47-SIRP[alpha] pathway in cancer immune evasion and potential therapeutic implications", CURRENT OPINION IN IMMUNOLOGY, (20120401), vol. 24, no. 2, doi:10.1016/j.coi.2012.01.010, ISSN 0952-7915, pages 225 - 232, XP055029985 [A] 1-9 * see abstract and pages 229-230 * |
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| SEARCH | - BYRNE JENNIFER C ET AL, "Bruton's Tyrosine Kinase Is Required for Apoptotic Cell Uptake via Regulating the Phosphorylation and Localization of Calreticulin", JOURNAL OF IMMUNOLOGY, (201305), vol. 190, no. 10, pages 5207 - 5215, XP002782998 [A] 1-9 * see abstract, pages 5207-5208, Fig.4 and 6 * |