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Production Of Extracellular Vesicles In Single-Cell Suspension Using Chemically-Defined Cell Culture Media - EP3684381

The patent EP3684381 was granted to Codiak Biosciences on Dec 7, 2022. The application was originally filed on Sep 20, 2018 under application number EP18858922A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3684381

CODIAK BIOSCIENCES
Application Number
EP18858922A
Filing Date
Sep 20, 2018
Status
Granted And Under Opposition
Sep 30, 2022
Grant Date
Dec 7, 2022
External Links
Slate, Register, Google Patents

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STRAWMANJul 31, 2023POTTER CLARKSONWITHDRAWN

Patent Citations (11) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
INTERNATIONAL-SEARCH-REPORTUS2009252749
INTERNATIONAL-SEARCH-REPORTUS2014044647
INTERNATIONAL-SEARCH-REPORTUS2014234263
INTERNATIONAL-SEARCH-REPORTUS2016113966
INTERNATIONAL-SEARCH-REPORTUS2016245812
INTERNATIONAL-SEARCH-REPORTWO2012131733
INTERNATIONAL-SEARCH-REPORTWO2017072744
OPPOSITIONUS7732129
OPPOSITIONWO2017039761
SEARCHEP2450032
SEARCHUS2016113966

Non-Patent Literature (NPL) Citations (18) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
INTERNATIONAL-SEARCH-REPORT- PACHLER et al., "A Good Manufacturing Practice-Grade Standard Protocol for Exclusively Human Mesenchymal Stromal Cell -Derived Extracellular Vesicles", Cytotherapy, (20170401), vol. 19, pages 458 - 472, XP055585278 [A] 1-6 * . entire document *
INTERNATIONAL-SEARCH-REPORT- LOBB et al., "Optimized Exosome Isolation Protocol for Cell Culture Supernatant and Human Plasma", Journal of Extracellular Vesicles, (20150717), vol. 4, no. 27031, pages 1 - 11, XP055279331 [Y] 5, 6 * . entire document *
OPPOSITION- Do Minh Aline, Et Al, "Characterization of Extracellular Vesicles Secreted in Lentiviral Producing HEK293SF Cell Cultures", Viruses, (20210101), vol. 13, no. 797, pages 1 - 24, XP093077910-
OPPOSITION- Merten O W, "Safety Issues of Animal Products Used in Serum-Free Media", Dev. Biol. Stand., (19990101), vol. 99, pages 167 - 180, XP093077913-
OPPOSITION- VOISARD D,ET AL, "Potential of cell retention techniques for large-scale high-density perfusion culture of suspended mammalian cells.", Biotechnology and Bioengineering, Hoboken, USA, (20030630), vol. 82, no. 7, doi:10.1002/bit.10629, ISSN 0006-3592, pages 751 - 765, XP002317548
OPPOSITION- Harshman Sean W, Et Al, "Characterization of multiple myeloma vesicles bylabel-free relative quantitation", Proteomics, (20130101), vol. 13, doi:10.1002/pmic.201300142, pages 3013 - 3029, XP093077915
OPPOSITION- Greening DW, Xu R, Ji H, Tauro BJ, Simpson RJ, "A protocol for exosome isolation and characterization: evaluation of ultracentrifugation, density-gradient separation, and immunoaffinity capture methods.", Greening DW, Xu R, Ji H, Tauro BJ, Simpson RJ, edited by Anton Posch, Proteomic Profiling : Methods and Protocols; IN: Methods in molecular biology, US , Humana Press, New York, NY , (20150101), vol. 1295, pages 179 - 209, doi:10.1007/978-1-4939-2550-6_15, ISBN 978-1-4939-2549-0, XP055548012
OPPOSITION- Jee Yon Kim; Yeon-Gu Kim; Gyun Min Lee, "CHO cells in biotechnology for production of recombinant proteins: current state and further potential", Applied Microbiology and Biotechnology, Berlin, DE , (20111209), vol. 93, no. 3, doi:10.1007/s00253-011-3758-5, ISSN 1432-0614, pages 917 - 930, XP035006081
OPPOSITION- WATSON DIONYSIOS C ET AL, "Efficient production and enhanced tumor delivery of engineered extracellular vesicles", Biomaterials, (20161001), vol. 105, doi:10.1016/J.BIOMATERIALS.2016.07.003, pages 195 - 205, XP002771478
OPPOSITION- Joon Chul Lee, Ho Nam Chang, Duk Jae Oh, "Recombinant Antibody Production by Perfusion Cultures of rCHO Cells in a Depth Filter Perfusion System", Biotechnology Progress, Hoboken, USA, (20050101), vol. 21, no. 1, doi:10.1021/bp0497942, ISSN 8756-7938, pages 134 - 139, XP055660865
OPPOSITION- Bence György, Hung Michelle E., Breakefield Xandra O., Leonard Joshua N., "Therapeutic Applications of Extracellular Vesicles: Clinical Promise and Open Questions", ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, US , (20150106), vol. 55, no. 1, doi:10.1146/annurev-pharmtox-010814-124630, ISSN 0362-1642, pages 439 - 464, XP055619511
OPPOSITION- Emma Petiot;Danielle Jacob;Stephane Lanthier;Verena Lohr;Sven Ansorge;Amine A Kamen, "Metabolic and Kinetic analyses of influenza production in perfusion HEK293 cell culture", BMC Biotechnology, (20110901), vol. 11, no. 1, doi:10.1186/1472-6750-11-84, ISSN 1472-6750, page 84, XP021108979
OPPOSITION- Dennis K. Jeppesen, Michael L. Hvam, Bjarke Primdahl-Bengtson, Anders T. Boysen, Bradley Whitehead, Lars Dyrskjøt, Torben F. Ørntoft, Kenneth A. Howard, Marie S. Ostenfeld, "Comparative analysis of discrete exosome fractions obtained by differential centrifugation", Journal of Extracellular Vesicles, (20140101), vol. 3, no. 1, doi:10.3402/jev.v3.25011, page 25011, XP055754535
OTHER- Anonymous, "CDM-HD: Chemically Defined Medium for High-Density Cell Culture", Fibercell Systems, (20180829), page 2pp, XP055938708-
OTHER- Anonymous, "Hollow Fiber Provides a Sweet Spot for Several Biomanufacturing Applications", cellculturedish.com, (20150919), pages 1 - 8, cellculturedish.com, URL: https://cellculturedish.com/hollow-fiber-provides-a-sweet-spot-for-several-biomanufacturing-applications/, (20220705), XP055938719-
OTHER- Anonymous, "Product Specification C5467", Sigma, page 1-
OTHER- WATSON DIONYSIOS C ET AL, "Efficient production and enhanced tumor delivery of engineered extracellular vesicles", Biomaterials, (20161001), vol. 105, doi:10.1016/J.BIOMATERIALS.2016.07.003, pages 195 - 205, XP002771478
OTHER- Joon Chul Lee, Ho Nam Chang, Duk Jae Oh, "Recombinant Antibody Production by Perfusion Cultures of rCHO Cells in a Depth Filter Perfusion System", Biotechnology Progress, American Chemical Society, (20050101), vol. 21, no. 1, doi:10.1021/bp0497942, ISSN 8756-7938, pages 134 - 139, XP055660865

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