Mutated Glycoprotein Of Vesicular Stomatitis Virus - EP3684786

The patent EP3684786 was granted to Centre National DE LA Recherche Scientifique Cnrs on Aug 14, 2024. The application was originally filed on Sep 24, 2018 under application number EP18773448A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3684786

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Application Number
EP18773448A
Filing Date
Sep 24, 2018
Status
Granted And Under Opposition
Jul 12, 2024
Grant Date
Aug 14, 2024
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions (2)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentativeOpposition Status

Get instant alerts for new oppositions and patent status changes

BOULT WADE TENNANTMay 14, 2025BOULT WADE TENNANTADMISSIBLE
DORRIESMay 14, 2025DORRIESADMISSIBLE

Patent Citations (5) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
INTERNATIONAL-SEARCH-REPORTUS2008124357
INTERNATIONAL-SEARCH-REPORTWO0119380
OPPOSITIONUS2008124357
OPPOSITIONWO0119380
OPPOSITIONWO2010040023

Non-Patent Literature (NPL) Citations (32) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- ALBERTINI, A.A.V.; BAQUERO, E.; FERLIN, A.; GAUDIN, Y., "Molecular and Cellular Aspects of Rhabdovirus Entry", Viruses, (20120000), vol. 4, pages 117 - 139-
DESCRIPTION- AMIRACHE, F.; LEVY, C.; COSTA, C.; MANGEOT, P.E.; TORBETT, B.E.; WANG, C.X.; NEGRE, D.; COSSET, F.L.; VERHOEYEN, E., "Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor", Blood, (20140000), vol. 123, pages 1422 - 1424-
DESCRIPTION- FERLIN, A.; RAUX, H.; BAQUERO, E.; LEPAULT, J.; GAUDIN, Y., "Characterization of pH-sensitive molecular switches that trigger the structural transition of vesicular stomatitis virus glycoprotein from the postfusion state toward the prefusion state", J Virol, (20140000), vol. 88, pages 13396 - 13409-
DESCRIPTION- ROCHE, S.; BRESSANELLI, S.; REY, F.A.; GAUDIN, Y., "Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G", Science, (20060000), vol. 313, pages 187 - 191-
DESCRIPTION- ROCHE, S.; REY, F.A.; GAUDIN, Y.; BRESSANELLI, S., "Structure of the prefusion form of the vesicular stomatitis virus glycoprotein g.", Science, (20070000), vol. 315, pages 843 - 848-
DESCRIPTION- "VSV-tumor selective replication and protein translation", Oncogene, (20050000), vol. 24, pages 7710 - 7719-
DESCRIPTION- FINKELSHTEIN, D.; WERMAN, A.; NOVICK, D.; BARAK, S.; RUBINSTEIN, M., "LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus", Proceedings of the National Academy of Sciences of the United States of America, (20130000), vol. 110, doi:doi:10.1073/pnas.1214441110, pages 7306 - 7311, XP055436675
DESCRIPTION- AMMAYAPPAN, A.; PENG, K.W.; RUSSELL, S.J., "Characteristics of oncolytic vesicular stomatitis virus displaying tumor-targeting ligands", J Virol, (20130000), vol. 87, doi:doi:10.1128/JVI.02240-13, pages 13543 - 13555, XP055122167
INTERNATIONAL-SEARCH-REPORT- NIKOLIC J ET AL, "Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein", NATURE COMMUNICATIONS, (20180312), vol. 9, no. 1, doi:10.1038/s41467-018-03432-4, pages 1 - 12, XP055518690 [XP] 1-18 * abstract; results; discussion; *
INTERNATIONAL-SEARCH-REPORT- FINKELSHTEIN D ET AL, "LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus", PROCEEDINGS NATIONAL ACADEMY OF SCIENCES PNAS, US, (20130415), vol. 110, no. 18, doi:10.1073/pnas.1214441110, ISSN 0027-8424, pages 7306 - 7311, XP055436675 [A] 1-15 * abstract; results; discussion; *
INTERNATIONAL-SEARCH-REPORT- AMMAYAPPAN A ET AL, "Characteristics of Oncolytic Vesicular Stomatitis Virus Displaying Tumor-Targeting Ligands", JOURNAL OF VIROLOGY., US, (20131002), vol. 87, no. 24, doi:10.1128/JVI.02240-13, ISSN 0022-538X, pages 13543 - 13555, XP055122167 [A] 1-15 * abstract; results; discussion;;; figure - *
OPPOSITION- Amirache, Et Al., "Mystery solved: VSV-G-LVs do not allow efficient qene transfer into unstimulated T cells, B cells, and HSCs because they lack LDL receptor", Blood, (20140101), vol. 123, no. 9, pages 1422 - 1424, XP055933750-
OPPOSITION- D11a - WO 2010/040023 A2 Figures as filed-
OPPOSITION- D12 - Experimental Report-
OPPOSITION- D13a - Supplementary Material of D13 (with two boxes added on page 6 to assist review)-
OPPOSITION- D13b - Alignment of Patent SEQ ID NO: 1 with variant 15 from D13-
OPPOSITION- D1a - supplementary information of D1-
OPPOSITION- D6a - supplementary information of D6-
OPPOSITION- D7 - Annex A - Post published Experimental data-
OPPOSITION- D7a - supplementary information of D7-
OPPOSITION- S. Roche ; A. A. V. Albertini ; J. Lepault ; S. Bressanelli ; Y. Gaudin, "Structures of vesicular stomatitis virus glycoprotein: membrane fusion revisited", Cellular and Molecular Life Sciences, Birkhäuser-Verlag, Ba, Ba , (20080317), vol. 65, no. 11, ISSN 1420-9071, pages 1716 - 1728, XP019619924-
OPPOSITION- Rücker Pia, Wieninger Silke A., Ullmann G. Matthias, Sticht Heinrich, "pH‐dependent molecular dynamics of vesicular stomatitis virus glycoprotein G", Proteins: Structure, Function, and Bioinformatics, John Wiley & Sons, Inc., US, US , (20121101), vol. 80, no. 11, doi:10.1002/prot.24145, ISSN 0887-3585, pages 2601 - 2613, XP093280665
OPPOSITION- Baquero Eduard, Albertini Aurélie Av, Gaudin Yves, "Recent mechanistic and structural insights on class III viral fusion glycoproteins", Current Opinion in Structural Biology, Elsevier Ltd., GB, GB , (20150801), vol. 33, doi:10.1016/j.sbi.2015.07.011, ISSN 0959-440X, pages 52 - 60, XP093280669
OPPOSITION- Beglova, N. Blacklow, S.C., "The LDL receptor: how acid pulls the trigger", Trends in Biochemical Sciences, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20050601), vol. 30, no. 6, doi:10.1016/j.tibs.2005.03.007, ISSN 0968-0004, pages 309 - 317, XP004945633
OPPOSITION- Buchholz Christian J.; Friedel Thorsten; Büning Hildegard, "Surface-Engineered Viral Vectors for Selective and Cell Type-Specific Gene Delivery", TRENDS IN BIOTECHNOLOGY., ELSEVIER PUBLICATIONS, CAMBRIDGE., GB, GB , (19000101), vol. 33, no. 12, doi:10.1016/j.tibtech.2015.09.008, ISSN 0167-7799, pages 777 - 790, XP029322458
OPPOSITION- Hastie Eric; Cataldi Marcela; Marriott Ian; Grdzelishvili Valery Z., "Understanding and altering cell tropism of vesicular stomatitis virus", Virus research, AMSTERDAM, NL, NL , (19000101), vol. 176, no. 1, doi:10.1016/j.virusres.2013.06.003, ISSN 0168-1702, pages 16 - 32, XP028690314
OPPOSITION- Hwang B-Y; Schaffer D V, "Engineering a serum-resistant and thermostable vesicular stomatitis virus G glycoprotein for pseudotyping retroviral and lentiviral vectors", Gene Therapy, Nature Publishing Group, London, GB, GB , (20130131), vol. 20, no. 8, doi:10.1038/gt.2013.1, ISSN 0969-7128, pages 807 - 815, XP037772492
OPPOSITION- Jovan Nikolic; Belot Laura; Raux Hélène; Legrand Pierre; Gaudin Yves; Albertini Aurélie A, "Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein", Nature Communications, (20180312), vol. 9, no. 1, doi:10.1038/s41467-018-03432-4, pages 1 - 12, XP055518690
OPPOSITION- D. Finkelshtein, A. Werman, D. Novick, S. Barak, M. Rubinstein, "LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus", Proceedings of the National Academy of Sciences (PNAS), National Academy of Sciences, (20130430), vol. 110, no. 18, doi:10.1073/pnas.1214441110, ISSN 0027-8424, pages 7306 - 7311, XP055436675
OPPOSITION- Joglekar Alok V., Sandoval Salemiz, "Pseudotyped Lentiviral Vectors: One Vector, Many Guises", Human Gene Therapy, Springer, US, US , (20171201), vol. 28, no. 6, doi:10.1089/hgtb.2017.084, ISSN 1946-6536, pages 291 - 301, XP055890845
OPPOSITION- Roche Stéphane, Rey Félix A., Gaudin Yves, Bressanelli Stéphane, "Structure of the Prefusion Form of the Vesicular Stomatitis Virus Glycoprotein G", Science - Author Manuscript, American Association for the Advancement of Science, US, US , (20070209), vol. 315, no. 5813, doi:10.1126/science.1135710, ISSN 0036-8075, pages 843 - 848, XP055878162
OPPOSITION- A. P. Lillis, L. B. Van Duyn, J. E. Murphy-Ullrich, D. K. Strickland, "LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies", Physiological Reviews, (20080701), vol. 88, no. 3, doi:10.1152/physrev.00033.2007, ISSN 00319333, pages 887 - 918, XP055159637

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents