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Heterodimers Of Glutamic Acid - EP3699162

The patent EP3699162 was granted to Molecular Insight Pharmaceuticals on Jun 29, 2022. The application was originally filed on Nov 7, 2007 under application number EP19214298A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3699162

MOLECULAR INSIGHT PHARMACEUTICALS
Application Number
EP19214298A
Filing Date
Nov 7, 2007
Status
Granted And Under Opposition
May 27, 2022
Grant Date
Jun 29, 2022
External Links
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TELIX INNOVATIONSJan 10, 2023DE CLERCQ & PARTNERSADMISSIBLE

Patent Citations (5) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS2004002478
DESCRIPTIONUS2004054190
DESCRIPTIONWO0222627
DESCRIPTIONWO03060523
OPPOSITIONUS2004054190

Non-Patent Literature (NPL) Citations (37) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- LUTHI-CARTER et al., J Pharm ExpTherap, (19980000), vol. 286, no. 2-
DESCRIPTION- TANG, H.BROWN, M.YE, Y.HUANG, G.ZHANG, Y.WANG, Y.ZHAI, H.CHEN, X.SHEN, T.Y.TENNISWOOD, M., "Prostate targeting ligands based on N-acetylated alpha-linked acidic dipeptidase", Biochem. Biophys. Res. Commun., (20030000), vol. 307, doi:10.1016/S0006-291X(03)01119-7, pages 8 - 14, XP002327104
EXAMINATION- CATHERINE FOSS ET AL., "Abstract 362: Synthesis and Validation of a Novel Small-Molecule Fluorescent Probe for PSMA Expression n Human Tumor Neovasculature.", MOLECULAR IMAGING, (2005), vol. 4, no. 3, pages 321 - 321, XP055762960-
EXAMINATION- CRYSTAL DUSICH ET AL., "Abstract 470: General Approach for the Preparation of Fluorescent PSMA/GCPII Inhibitors", MOLECULAR IMAGING, (2006), vol. 5, no. 3, pages 322 - 323, XP055762959-
OPPOSITION- Anonymous, "Bombesin", Wikipedia, (20230101), pages 1 - 4, Wikipedia, URL: https://en.wikipedia.org/wiki/Bombesin, (20230316), XP093032298-
OPPOSITION- Anonymous, "Pendetide", Wikipedia, pages 1 - 3, Wikipedia, URL: https://en.wikipedia.org/wiki/Pendetide, (20230316), XP093032295-
OPPOSITION- Anonymous, "Safety data sheet according to 1907/2006/EC, Article 31 SECTION 1: Identification of the substance/mixture and of the company/ undertaking. Bromopentacarbonylrhenium", (20170703), pages 1 - 8, URL: https://kingdomcoffee.co.uk/pub/media/productattach/c/o/coshh_sheet_-_jura_descale_tablet_1.pdf, (20201127), XP055754686-
OPPOSITION- Brückner Christian, Karunaratne Veranja, Rettig Steven J, Dolphin David, "Synthesis of mesophenyl-4,6-dipyrrins, I preparation of their Cu(ll), Ni(ll), and Zn(ll) chelates, and structural characterization of bis[meso-phenyl=4,6=dipyrrinato]Ni(l", Can. J. Chem, (19960101), vol. 74, pages 2182 - 2193, XP093032271-
OPPOSITION- Catherine Foss, Crystal Dusich, Ronnie Mease, Anirban Maitra, Martin Romper., "Abstract ID: 362 Synthesis and Validation of a Novel Small-Molecule Fluorescent Probe for PSMA Expression in Human Tumor Neovasculature", Molecular Imaging, (20050701), vol. 4, no. 3, pages 209 - 210, XP055762960-
OPPOSITION- CATHERINE FOSS et al., "Abstract 362: Synthesis and Validation of a Novel Small- Molecule Fluorescent Probe for PSMA Expression in Human Tumor Neovasculature", MOLECULAR IMAGING, (20050000), vol. 4, no. 3, pages 321 - 321, XP055762960-
OPPOSITION- CRYSTAL DUSICH et al., "Abstract 470: General Approach for the Preparation of Fluorescent PSMA/GCPII Inhibitors", MOLECULAR IMAGING, (20060000), vol. 5, no. 3, pages 322 - 323, XP055762959-
OPPOSITION- Han Misop, Partin Alan W., "Current Clinical Applications of the 111 In-capromab Pendetide Scan (ProstaScint ® Scan, Cyt-356)", REVIEWS IN UROLOGY, (20010101), vol. 3, no. 4, pages 165 - 171, XP093032232-
OPPOSITION- Hinkle George H. et al, "Prostate Cancer Abdominal Metastases Detected with Indium-111 Capromab Pendetide", THE JOURNAL OF NUCLEAR MEDICINE, (19980401), vol. 39, no. 4, pages 650 - 652, XP093032229-
OPPOSITION- Hofmann M., "Feasibility of Ga-68-DOTABOM PET in prostate carcinoma patients", Eur J Nucl Med Mol Imaging, (20040101), vol. 31, page S253, XP093032264-
OPPOSITION- Jeroen R. Mesters et al, "Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer", The EMBO Journal, (20060322), vol. 25, no. 6, pages 1375 - 1384, XP055766101-
OPPOSITION- KRATOCHWIL CLEMENS ET AL, "PMPA for Nephroprotection in PSMA-Targeted Radionuclide Therapy of Prostate Cancer", JOURNAL OF NUCLEAR MEDICINE, (20150201), vol. 56, no. 2, pages 293 - 298, XP002779406-
OPPOSITION- MAECKE H R, HOFMANN M, HABERKORN U, "68GA-LABELED PEPTIDES IN TUMOR IMAGING", The Journal of Nuclear Medicine, Society of Nuclear Medicine, US, US , (20050101), vol. 46, no. 01, SUPPL., ISSN 0161-5505, pages 172S - 178S, XP008051799-
OPPOSITION- SARVA JAYAPRAKASH ET AL., "Design and Synthesis of a PSMA Inhibitor-Doxorubicin Conjugate for Targeted Prostate Cancer Therapy", ChemMedChem, (20060101), vol. 1, pages 299 - 302, XP002390389-
OPPOSITION- Treibs Alfred, Kreuzer Franz-Heinrich, "Difluorboryl-Komplexe von Di- und Tripyrrylmethenen", JUSTUS LIEBIGS ANNALEN DER CHEMIE, VERLAG CHEMIE GMBH., DE, DE , (19681213), vol. 718, no. 1, doi:10.1002/jlac.19687180119, ISSN 0075-4617, pages 208 - 223, XP093032268
OPPOSITION- Zechmann Christian M. et al, "Radiation dosimetry and first therapy results with a 124I/131I-labeled small molecule (MIP-1095) targeting PSMA for prostate cancer therapy", European Journal of Nuclear Medicine and Molecular Imaging, Springer Berlin Heidelberg, Berlin/Heidelberg, Berlin/Heidelberg, (20140701), vol. 41, no. 7, doi:10.1007/s00259-014-2713-y, ISSN 1619-7070, pages 1280 - 1292, XP093032318
OPPOSITION- Guilarte, T.R. et al, "Glutamate carboxypeptidase II levels in rodent brain using [^1^2^5I]DCIT quantitative autoradiography", Neuroscience Letters, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20051028), vol. 387, no. 3, doi:10.1016/j.neulet.2005.06.015, ISSN 0304-3940, pages 141 - 144, XP005029882
OPPOSITION- James Shelly et al, "Extension of the Single Amino Acid Chelate Concept (SAAC) to Bifunctional Biotin Analogues for Complexation of the M(CO) 3 +1 Core (M = Tc and Re):  Syntheses, Characterization, Biotinidase Stability, and Avidin Binding", Bioconjugate Chemistry, American Chemical Society, US, US , (20060501), vol. 17, no. 3, doi:10.1021/bc050297w, ISSN 1043-1802, pages 579 - 589, XP093032224
OPPOSITION- KOZIKOWSKI A.P. ET AL., "Design of remarkably simple, yet potent urea-based inhibitors of Glutamate carboxypeptidase II (NAALADase)", JOURNAL OF MEDICINAL AND PHARMACEUTICAL CHEMISTRY., AMERICAN CHEMICAL SOCIETY. EASTON., US, US , (20010201), vol. 44, no. 3, doi:10.1021/jm000406m, pages 298 - 301, XP002196918
OPPOSITION- KOZIKOWSKI A P et al., "Synthesis of Urea-Based Inhibitors as Active Site Probes of Glutamate Carboxypeptidase II: Efficacy as Analgesic Agents", JOURNAL OF MEDICINAL CHEMISTRY, US, (20040302), vol. 47, ISSN 0022-2623, pages 1729 - 1738, XP002390387
OPPOSITION- ZHOU JIA ET AL, "NAAG peptidase inhibitors and their potential for diagnosis and therapy.", Nature Reviews Drug Discovery, Nature Publishing Group, GB, GB , (20051201), vol. 4, no. 12, doi:10.1038/nrd1903, ISSN 1474-1776, pages 1015 - 1026, XP002514725
OPPOSITION- Tesson Mathias et al, "Preliminary evaluation of prostate-targeted radiotherapy using 131I-MIP-1095 in combination with radiosensitising chemotherapeutic drugs", Journal of pharmacy and pharmacology : JPP, John Wiley & Sons Ltd, London, GB, GB , (20160620), vol. 68, no. 7, doi:10.1111/jphp.12558, ISSN 0022-3573, pages 912 - 921, XP093032328
OPPOSITION- Ragab Sherif S, "Synthesis and photolysis of new BODIPY derivatives with chelated boron centre", Journal of Porphyrins and Phthalocyanines, (20210101), vol. 25, doi:10.1142/S1088424621500516, pages 818 - 824, XP093032288
OPPOSITION- S. M. Hillier et al, "Preclinical Evaluation of Novel Glutamate-Urea-Lysine Analogues That Target Prostate-Specific Membrane Antigen as Molecular Imaging Pharmaceuticals for Prostate Cancer", Cancer research, American Association for Cancer Research, (20090901), vol. 69, no. 17, doi:10.1158/0008-5472.CAN-09-1682, ISSN 00085472, pages 6932 - 6940, XP055020196
OPPOSITION- CATHERINE A FOSS et al., "Radiolabeled Small-Molecule Ligands for Prostate-Specific Membrane Antigen: in Vivo Imaging in Experimental Models of Prostate Cancer", CLINICAL CANCER RESEARCH, US, (20050601), vol. 11, no. 11, ISSN 1078-0432, pages 4022 - 4028, XP008109807
OPPOSITION- POMPER M G, ET AL., "11C-MCG: SYNTHESIS, UPTAKE SELECTIVITY, AND PRIMATE PET OF A PROBE FOR GLUTAMATE CARBOXYPEPTIDASE II (NAALADASE)", MOLECULAR IMAGING, Sage Publications, Inc., US, US , (20020401), vol. 01, no. 02, doi:10.1162/153535002320162750, ISSN 1535-3508, pages 96 - 101, XP008017837
OPPOSITION- S. M. Hillier et al, "123I-MIP-1072, a Small-Molecule Inhibitor of Prostate-Specific Membrane Antigen, Is Effective at Monitoring Tumor Response to Taxane Therapy", The Journal of Nuclear Medicine, Society of Nuclear Medicine, (20110701), vol. 52, no. 7, doi:10.2967/jnumed.110.086751, ISSN 01615505, pages 1087 - 1093, XP055138965
OPPOSITION- J. A. Barrett et al, "First-in-Man Evaluation of 2 High-Affinity PSMA-Avid Small Molecules for Imaging Prostate Cancer", The Journal of Nuclear Medicine, Society of Nuclear Medicine, US, US , (20130301), vol. 54, no. 3, doi:10.2967/jnumed.112.111203, ISSN 0161-5505, pages 380 - 387, XP055280719
OPPOSITION- Alsimaree Abdulrahman A. et al, "Pyrrolylquinoline-BF2 and BPh2 BODIPY-Type Analogues: Synthesis, Structural Analysis and Photophysical Properties", Crystals, vol. 11, no. 1103, doi:10.3390/cryst11091103, pages 1 - 11, XP093032265
OTHER- Catherine Foss, Crystal Dusich, Ronnie Mease, Anirban Maitra, Martin Romper, "Abstract ID: 362 Synthesis and Validation of a Novel Small-Molecule Fluorescent Probe for PSMA Expression in Human Tumor Neovasculature", Molecular Imaging, (20050700), vol. 4, no. 3, pages 209 - 210, XP055762960-
OTHER- Crystal Dusich, Ron Mease, Catherine Foss, Martin Pomper, "Abstract ID:470 General Approach for the Preparation of Fluorescent PSMA/GCPH Inhibitors", Molecular Imaging, (20060700), vol. 5, no. 3, pages 322 - 323, XP055762959-
SEARCH- KOZIKOWSKI A P ET AL, "Synthesis of Urea-Based Inhibitors as Active Site Probes of Glutamate Carboxypeptidase II: Efficacy as Analgesic Agents", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (20040302), vol. 47, doi:10.1021/JM0306226, ISSN 0022-2623, pages 1729 - 1738, XP002390387 [A] 1-16 * compounds 8b,8d *
SEARCH- CATHERINE A FOSS ET AL, "Radiolabeled Small-Molecule Ligands for Prostate-Specific Membrane Antigen: in Vivo Imaging in Experimental Models of Prostate Cancer", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, (20050601), vol. 11, no. 11, doi:10.1158/1078-0432.CCR-04-2690, ISSN 1078-0432, pages 4022 - 4028, XP008109807 [A] 1-16 * [125I]DCIT *

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