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The patent EP3710129 was granted to Novasep Process on Feb 12, 2025. The application was filed on Nov 16, 2018 under application number EP18827161A. The patent is currently recorded with a legal status of "Granted And Under Opposition".
A chromatographic separation method that enables real-time optimization of operating parameters in cyclic multicolumn chromatography systems. The method involves detecting characteristic points in the concentration histories of the extract and raffinate streams, comparing their positions to target values, and adjusting the carrier volume to maintain optimal separation conditions. The method also enables real-time measurement of purity and yield of the collected fractions, allowing for adaptive control of the separation process.

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