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Plasmid System - EP3722434

The patent EP3722434 was granted to Ascend Gene And Cell Therapies on Jul 27, 2022. The application was originally filed on Apr 12, 2019 under application number EP19169121A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3722434

ASCEND GENE AND CELL THERAPIES
Application Number
EP19169121A
Filing Date
Apr 12, 2019
Status
Granted And Under Opposition
Jun 24, 2022
Grant Date
Jul 27, 2022
External Links
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OETKEApr 27, 2023OETKEADMISSIBLE

Patent Citations (12) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONWO2013029030
DESCRIPTIONWO2013078400
DESCRIPTIONWO2016075473
DESCRIPTIONWO2016181123
DESCRIPTIONWO2017096164
OPPOSITIONWO03074686
OPPOSITIONWO2020208379
OTHERUS7208315
OTHERWO2015038958
SEARCHCN108048483
SEARCHUS2003103939
SEARCHUS2005080027

Non-Patent Literature (NPL) Citations (34) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
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OPPOSITION- GRIMM D. et al., "Novel Tools for Production and Purification of Recombinant Adenoassociated Virus Vectors", Human Gene Therapy, (19980000), vol. 9, pages 2745 - 2760, XP002093963
OPPOSITION- Emmerling Verena V., Pegel Antje, Milian Ernest G., Venereo‐sanchez Alina, Kunz Marion, Wegele Jessica, Kamen Amine A., Kochanek Stefan, Hoerer Markus, "Supporting Information - Rational plasmid design and bioprocess optimization to enhance recombinant adeno‐associated virus (AAV) productivity in mammalian cells", Biotechnology Journal, WILEY-VCH VERLAG, WEINHEIM, DE, DE , (20150101), doi:10.1002/biot.201500176, ISSN 1860-6768, XP093151807
OPPOSITION- Verena V. Emmerling; Antje Pegel; Ernest G. Milian; Alina Venereo‐Sanchez; Marion Kunz; Jessica Wegele; Amine A. Kamen; Stefan Kochanek; Markus Hoerer, "Rational plasmid design and bioprocess optimization to enhance recombinant adeno‐associated virus (AAV) productivity in mammalian cells", Biotechnology Journal, WILEY-VCH VERLAG, WEINHEIM, DE, DE , (20150924), vol. 11, no. 2, doi:10.1002/biot.201500176, ISSN 1860-6768, pages 290 - 297, XP072400776
OPPOSITION- APONTE-UBILLUS J. J. et al., "Molecular design for recombinant adeno-associated virus (rAAV) vector production", Applied Microbiology and Biotechnology, (20180000), vol. 102, doi:10.1007/s00253-017-8670-1, pages 1045 - 1054, XP036390095
OPPOSITION- Magalie Penaud-Budloo, Achille Francois, Nathalie Clement, Eduard Ayuso, "Pharmacology of Recombinant Adeno-associated Virus Production", Molecular therapy - Methods & clinical development, Nature Publishing Group, GB, GB , (20180301), vol. 8, doi:10.1016/j.omtm.2018.01.002, ISSN 2329-0501, pages 166 - 180, XP055713307
OPPOSITION- GRIMM D. et al., "Helper Virus-Free, Optically Controllable, and Two-Plasmid-Based Production of Adeno-associated Virus Vectors of Serotypes 1 to 6", Molecular Therapy, (20030000), vol. 7, no. 6, doi:10.1016/S1525-0016(03)00095-9, pages 839 - 850, XP002256403
OPPOSITION- GRIMM D. et al., "Titration of AAV-2 particles via a novel capsid ELISA: packaging of genomes can limit production of recombinant AAV-2", Gene Therapy, (19990000), vol. 6, doi:10.1038/sj.gt.3300946, pages 1322 - 1330, XP037774023
OPPOSITION- MERTEN O.-W. et al., "Current issues in adeno-associated viral vector production", Gene Therapy, (20050000), vol. 12, doi:10.1038/sj.gt.3302615, pages S51 - S61, XP037774007
OPPOSITION- FARRIS K. D. et al., "Improved Splicing of Adeno-Associated Viral (AAV) Capsid Protein-Supplying Pre-mRNAs Leads to Increased Recombinant AAV Vector Production", Human Gene Therapy, (20080000), vol. 19, doi:10.1089/hum.2008.118, pages 1421 - 1427, XP093113129
OPPOSITION- OGASAWARA Y. et al., "Efficient Production of Adeno-associated Virus Vectors Using Split-type Helper Plasmids", Jpn. J. Cancer Res., (19990000), vol. 90, doi:10.1111/j.1349-7006.1999.tb00772.x, pages 476 - 483, XP055572245
OPPOSITION- MERTEN O.-W., "AAV vector production: state of the art developments and remaining challenges", Cell & Gene Therapy Insights, (20160000), doi:10.18609/cgti.2016.067, pages 521 - 551, XP055649764
OPPOSITION- Otto-Wilhelm Merten, "AAV vector production: state of the art developments and remaining challenges", Cell and Gene Therapy Insights, (20161201), vol. 2, no. 5, doi:10.18609/cgti.2016.067, ISSN 2059-7800, pages 521 - 551, XP055649764
OPPOSITION- WRIGHT J. F., "Product-Related Impurities in Clinical-Grade Recombinant AAV Vectors: Characterization and Risk Assessment", Biomedicines, (20140000), vol. 2, doi:10.3390/biomedicines2010080, pages 80 - 97, XP055182498
OTHER- Verena V. Emmerling et al, "Rational plasmid design and bioprocess optimization to enhance recombinant adeno‐associated virus (AAV) productivity in mammalian cells", Biotechnology Journal, WILEY-VCH VERLAG, WEINHEIM, DE, DE , (20150924), vol. 11, no. 2, doi:10.1002/biot.201500176, ISSN 1860-6768, pages 290 - 297, XP072400776
OTHER- GRIMM et al., "Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6", Molecular Therapy, (20030000), vol. 7, no. 6, doi:10.1016/S1525-0016(03)00095-9, XP002256403
OTHER- MERTEN et al., "Current issues in adeno-associated viral vector production", Gene, (20050000), vol. 12, doi:10.1038/sj.gt.3302615, pages S51 - S61, XP037774007
OTHER- Farris K. David, Pintel David J., "Improved Splicing of Adeno-Associated Viral (AAV) Capsid Protein-Supplying Pre-mRNAs Leads to Increased Recombinant AAV Vector Production", HUMAN GENE THERAPY, Mary Ann Liebert, Inc. Publishers, GB, GB , (20081201), vol. 19, no. 12, doi:10.1089/hum.2008.118, ISSN 1043-0342, pages 1421 - 1427, XP093113129
OTHER- OGASAWARA et al., "Efficient Production of Adeno-associated Virus Vectors Using Split-type Helper Plasmids", Jpn. J. Cancer Res., (19990000), vol. 90, doi:10.1111/j.1349-7006.1999.tb00772.x, pages 476 - 483, XP055572245
OTHER- MERTEN O-W., "AAV vector production: state of the art developments and remaining challenges", Cell & Gene Therapy Insights, (20160000), vol. 2, no. 5, doi:10.18609/cgti.2016.067, pages 521 - 551, XP055649764
OTHER- WRIGHT J. F., "Product-Related Impurities in Clinical-Grade Recombinant AAV Vectors: Characterization and Risk Assessment", Biomedicines, (20140000), vol. 2, doi:10.3390/biomedicines2010080, pages 80 - 97, XP055182498

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