| DESCRIPTION | - ARRUDA et al., Blood, (20100000), vol. 115, pages 4678 - 88 |
| DESCRIPTION | - AYUSO et al., Gene Ther., (20100000), vol. 17, pages 503 - 10 |
| DESCRIPTION | - BARASH et al., Biochem. Biophys. Res. Comm., (20020000), vol. 294, pages 835 - 42 |
| DESCRIPTION | - BOUTIN et al., Hum Gene Ther., (20100000), vol. 21, pages 704 - 12 |
| DESCRIPTION | - CALCEDO et al., Clin Vaccine Immunol., (20110000), vol. 18, pages 1586 - 8 |
| DESCRIPTION | - CHOI et al., J. Virol., (20050000), vol. 79, no. 11, pages 6801 - 7 |
| DESCRIPTION | - DULL et al., J Virol., (19981100), vol. 72, no. 11, pages 8463 - 71 |
| DESCRIPTION | - ERLES et al., J Med Virol., (19990000), vol. 59, pages 406 - 11 |
| DESCRIPTION | - GALJAARD et al., Clin Chim Acta, (19730000), vol. 49, no. 3, pages 361 - 75 |
| DESCRIPTION | - "GenBank", Database accession no. ADF 13949.1 |
| DESCRIPTION | - GEORGE et al., N Engl J Med., (20170000), vol. 377, pages 2215 - 2227 |
| DESCRIPTION | - GUIDO et al., World J. Gastroenterol., (20160000), vol. 22, pages 8684 - 8697 |
| DESCRIPTION | - HAURIGOT et al., Mol Ther., (20100000), vol. 18, pages 1318 - 29 |
| DESCRIPTION | - HULTING et al., FEMS Microbiol Lett., (20090000), vol. 298, pages 44 - 50 |
| DESCRIPTION | - JORDAN et al., N Engl. J Med., (20170000), vol. 377, page 5 |
| DESCRIPTION | - LANNERGARDGUSS, FEMS Microbiol Lett., (20060000), vol. 262, pages 230 - 235 |
| DESCRIPTION | - LI et al., Gene Ther., (20120000), vol. 19, pages 288 - 94 |
| DESCRIPTION | - MANNO et al., Nat Med., (20060000), vol. 12, pages 342 - 7 |
| DESCRIPTION | - MANNUCCI et al., N Engl J Med., (20010000), vol. 344, pages 1773 - 9 |
| DESCRIPTION | - MASAT et al., Discov Med., (20130000), vol. 15, pages 379 - 89 |
| DESCRIPTION | - MCCARTY et al., Annu Rev Genet., (20040000), vol. 38, pages 819 - 45 |
| DESCRIPTION | - MCCARTY et al., Gene Ther., (20010000), vol. 8, no. 16, pages 1248 - 54 |
| DESCRIPTION | - MCCARTY, Mol. Ther., (20080000), vol. 16, no. 10, pages 1648 - 56 |
| DESCRIPTION | - MELIANI et al., Hum Gene Ther Methods., (20150000), vol. 26, pages 45 - 53 |
| DESCRIPTION | - MENDELL et al., N. Engl. J. Med., (20170000), vol. 377, pages 1713 - 1722 |
| DESCRIPTION | - MINGOZZI et al., Blood, (20130000), vol. 122, pages 23 - 36 |
| DESCRIPTION | - MINGOZZI et al., Gene Ther., (20130000), vol. 20, pages 417 - 24 |
| DESCRIPTION | - MINGOZZI et al., Sci Transl Med., (20130000), vol. 5, page 194ra92 |
| DESCRIPTION | - NALDINI et al., Proc. Natl. Acad. Sci. USA, (19960000), vol. 93, pages 11382 - 11388 |
| DESCRIPTION | - NATHWANI et al., N Engl J Med., (20110000), vol. 365, pages 2357 - 65 |
| DESCRIPTION | - NATHWANI et al., N Engl J Med., (20140000), vol. 371, pages 1994 - 2004 |
| DESCRIPTION | - PENZES et al., J. Gen. Virol., (20150000), vol. 96, pages 2769 - 2779 |
| DESCRIPTION | - ROEKRING et al., Virus Res., (20020000), vol. 87, pages 79 - 87 |
| DESCRIPTION | - ROOPENIAN et al., J Immunol., (20030000), vol. 170, pages 3528 - 33 |
| DESCRIPTION | - RYAN et al., Mol Immunol., (20080000), vol. 45, pages 1837 - 46 |
| DESCRIPTION | - SCALLAN et al., Blood, (20060000), vol. 108, pages 1810 - 27 |
| DESCRIPTION | - Science, (19960000), vol. 272, pages 263 - 267 |
| DESCRIPTION | - TRAVIS et al., Biochim Biophys Acta, (20000000), vol. 1477, pages 35 - 50 |
| DESCRIPTION | - TRAVIS et al., Trends Microbiol., (19950000), vol. 3, pages 405 - 7 |
| DESCRIPTION | - VON PAWEL-RAMMINGEN et al., Curr Opin Microbiol., (20030000), vol. 6, pages 50 - 5 |
| DESCRIPTION | - ZUFFEREY et al., Nat. Biotechnol., (19970000), vol. 15, pages 871 - 875 |
| DESCRIPTION | - MCCARTY D M, "Self-complementary AAV vectors; advances and applications", Mol. Ther., (20081000), vol. 16, no. 10, doi:doi:10.1038/mt.2008.171, pages 1648 - 51, XP002714134 |
| EXAMINATION | - A Lamarre ET AL, "Protection from lethal coronavirus infection by immunoglobulin fragments", The Journal of Immunology, UNITED STATES, (19950415), page 3975, URL: http://www.jimmunol.org/cgi/content/abstract/154/8/3975, XP055185883 |
| EXAMINATION | - Anonymous, "Hansa Medical : Annual report 2016", Hansa Medical : Annual report 2016, Hansa Medical, Hansa Medical : Annual report 2016, URL: https://mb.cision.com/Main/1219/2250520/664499.pdf // https://news.cision.com/hansa-biopharma-ab/r/hansa-medical-publishes-the-annual-report-for-2016,c2250520, (20210924), XP055844501 |
| EXAMINATION | - Masat Elisa, "Humoral Immunity to AAV Vectors in Gene Therapy: Challenges and Potential Solutions - Elisa Masat - Discovery Medicine", Discovery Medicine, (20130627), URL: https://www.discoverymedicine.com/Elisa-Masat/2013/06/27/humoral-immunity-to-aav-vectors-in-gene-therapy-challenges-and-potential-solutions/, (20210924), XP055844547 |
| EXAMINATION | - Virginie Monteilhet ET AL, "A 10 Patient Case Report on the Impact of Plasmapheresis Upon Neutralizing Factors Against Adeno-associated Virus (AAV) Types 1, 2, 6, and 8", Molecular Therapy, US, (20111101), vol. 19, no. 11, doi:10.1038/mt.2011.108, ISSN 1525-0016, pages 2084 - 2091, XP055367781 |
| EXAMINATION | - Jordan Stanley C. ET AL, "APPENDIX: IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation", The New England journal of medicine, US, vol. 377, no. 5, doi:10.1056/NEJMoa1612567, ISSN 0028-4793, (20170803), pages 1 - 8, URL: https://www.nejm.org/doi/suppl/10.1056/NEJMoa1612567/suppl_file/nejmoa1612567_appendix.pdf, XP055844310 |
| EXAMINATION | - Stanley C. Jordan ET AL, "IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation", The New England journal of medicine, US, (20170803), vol. 377, no. 5, doi:10.1056/NEJMoa1612567, ISSN 0028-4793, pages 442 - 453, XP055527161 |
| EXAMINATION | - Vedell Louis Jeune ET AL, "Pre-existing Anti-Adeno-Associated Virus Antibodies as a Challenge in AAV Gene Therapy", Human Gene Therapy Methods, (20130401), vol. 24, no. 2, doi:10.1089/hgtb.2012.243, ISSN 1946-6536, pages 59 - 67, XP055563307 |
| EXAMINATION | - Winstedt Lena ET AL, "Complete Removal of Extracellular IgG Antibodies in a Randomized Dose-Escalation Phase I Study with the Bacterial Enzyme IdeS - A Novel Therapeutic Opportunity", PLOS ONE, vol. 10, no. 7, doi:10.1371/journal.pone.0132011, (20150715), page e0132011, URL: https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0132011/1/pone.0132011.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&[email protected]/20210920/auto/storage/goog4_request&X-Goog-Date=20210920T113857Z&X-Goog-Expires=86400&X-Goog-SignedHeaders=h, XP055842658 |
| INTERNATIONAL-SEARCH-REPORT | - Kyoko Tomita, "Correlation between Adenovirus-neutralizing Antibody Titer and Adenovirus Vector-mediated Transduction Efficiency Following Intratumoral Injection", Anticancer Research, (20120101), pages 1145 - 1152, URL: http://ar.iiarjournals.org/content/32/4/1145.full.pdf#page=1&view=FitH, (20181127), XP055527280 [A] 1-71 * title * |
| INTERNATIONAL-SEARCH-REPORT | - RAHMAN A ET AL, "Specific depletion of human anti-adenovirus antibodies facilitates transduction in an in vivo model for systemic gene therapy", MOLECULAR THERAPY : THE JOURNAL OF THE AMERICAN SOCIETY OF GENE THERAPY, ACADEMIC PRESS ; NATURE PUBLISHING GROUP, US, (20010501), vol. 3, no. 5, doi:10.1006/MTHE.2001.0316, ISSN 1525-0016, pages 768 - 778, XP002977532 [A] 1-71 * the whole document * |
| INTERNATIONAL-SEARCH-REPORT | - P Colella ET AL, "Emerging Issues in AAV-Mediated In Vivo Gene Therapy.", Mol Ther Methods Clin Dev., doi:10.1016/j.omtm.2017.11.007, (20171201), pages 87 - 104, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758940/pdf/main.pdf, (20180925), XP055509603 [A] 1-77 * the whole document * |
| INTERNATIONAL-SEARCH-REPORT | - JULIE R DELLINGER, "A Bacterial IgG-Degrading Enzyme to Unhinge Antibodies", THE NEW ENGLAND JOURNAL OF MEDICINE, - NEJM -, US, (20170803), vol. 377, no. 5, doi:10.1056/NEJMe1706903, ISSN 0028-4793, pages 487 - 489, XP055527722 [A] 1-71 * the whole document * |
| OPPOSITION | - A Lamarre, P J Talbot, "Protection from lethal coronavirus infection by immunoglobulin fragments", The Journal of Immunology, United States, (19950415), vol. 154, no. 8, pages 3975 - 3984, XP055185883 |
| OPPOSITION | - Anonymous, "Hansa Medical : Annual report 2016", Hansa Medical : Annual report 2016, Hansa Medical, (20170426), Hansa Medical : Annual report 2016, URL: https://mb.cision.com/Main/1219/2250520/664499.pdf // https://news.cision.com/hansa-biopharma-ab/r/hansa-medical-publishes-the-annual-report-for-2016,c2250520, (20210924), XP055844501 |
| OPPOSITION | - Anonymous, "Hansa Medical : Annual report 2016", Hansa Medical : Annual report 2016, Hansa Medical, pages 1 - 90, Hansa Medical : Annual report 2016, URL: https://mb.cision.com/Main/1219/2250520/664499.pdf // https://news.cision.com/hansa-biopharma-ab/r/hansa-medical-publishes-the-annual-report-for-2016,c2250520, (20210924), XP055844501 |
| OPPOSITION | - Anonymous , "hypothetical protein [Streptococcus pyogenes] ", Protein, (20130515), Database accession no. WP_010922160, URL: Genbank, XP093105457 |
| OPPOSITION | - Anonymous, "immunoglobulin G-degrading enzyme IdeS [Streptococcus pyogenes]", Protein, (20201103), Database accession no. WP_136093735, URL: Genbank, XP093166193 |
| OPPOSITION | - Bazin-Redureau Martine I., Renard Catherine B.; Scherrmann, Jean-Michel G., "Pharmacokinetics of heterologous and homologous immunoglobulin G, F(ab')2 and Fab after intravenous administration in the rat", J. Pharm. Pharmacol, (19970101), vol. 49, no. 16, doi:10.1111/j.2042-7158.1997.tb06795.x, pages 277 - 281, XP055907636 |
| OPPOSITION | - Bazin-Redureau M, Et Al, "Interspecies scaling of clearance and volume of distribution for horse antivenom F(ab')2", Toxicology and Applied Pharmacology, (19980101), vol. 150, pages 295 - 300, XP093066031 |
| OPPOSITION | - BAZIN-REDUREAU MI et al., "Pharmacokinetics of Heterologous and Homologous Immunoglobulin G, F(ab‘)2 and Fab after Intravenous Administration in the Ra", J Pharm March Pharmacol, (19970000), vol. 49, no. 3, pages 277 - 281, XP055907636 |
| OPPOSITION | - Burvenich, I.J.G. Schoonooghe, S. Blanckaert, P. Bacher, K. Vervoort, L. Coene, E. Mertens, N. De Vos, F. Slegers, G., "Biodistribution and planar gamma camera imaging of ^1^2^3I- and ^1^3^1I-labeled F(ab')"2 and Fab fragments of monoclonal antibody 14C5 in nude mice bearing an A549 lung tumor", Nuclear Medicine and Biology, ELSEVIER, NY., US, US , (20070323), vol. 34, no. 3, ISSN 0969-8051, pages 257 - 265, XP005935422 |
| OPPOSITION | - Catherine S Manno, Glenn F Pierce, Valder R Arruda, Bertil Glader, Margaret Ragni, John J E Rasko, Margareth C Ozelo, Keith Hoots, Philip Blatt, Barbara Konkle, Michael Dake, Robin Kaye, Mahmood Razavi, Albert Zajko, James Zehnder, Pradip Rustagi , Hiroyuki Nakai, Amy Chew, Debra Leonard, J Fraser Wright, Ruth R Lessard, Jürg M Sommer, Michael Tigges, Denise Sabatino, Alvin Luk, Haiyan Jiang, Federico Mingozzi, Linda Couto, Hildegund C Ertl, Katherine A High , Mark A Kay, "Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response.", Nature Medicine, New York, (20060301), vol. 12, no. 3, doi:10.1038/nm1358, ISSN 1078-8956, pages 342 - 347, XP002578131 |
| OPPOSITION | - Covell David G, Barbet Jacques, Holton Oscar D, Black Christopher D V, Parker R J, Weinstein John N, "Pharmacokinetics of Monoclonal Immunoglobulin G1, F(ab')2, and Fab' in Mice", Cancer Research, (19860801), vol. 46, no. 8, pages 3969 - 3978, XP055907644 |
| OPPOSITION | - COVELL DG et al., "Pharmacokinetics of Monoclonal Immunoglobulin G1, F(ab‘)2, and Fab’ in Mice", Cancer Res., (19860800), vol. 1986468, pages 3969 - 3978, XP055907644 |
| OPPOSITION | - Cui Jiannan, Et Al, "Equine Immunoglobulin and Equine Neutralizing F(ab')2 Protect Mice from West Nile Virus Infection", Viruses, (20161218), vol. 8, no. 332, pages 1 - 11, XP093066028 |
| OPPOSITION | - D J Hnatowich , M Gionet, M Rusckowski, D A Siebecker, J Roche, D Shealy, J A Mattis, J Wilson, J McGann, R E Hunter, "Pharmacokinetics of 111In-labeled OC-125 antibody in cancer patients compared with the 19-9 antibody", Cancer Research, (19871115), vol. 47, pages 6111 - 6117, XP093066030 |
| OPPOSITION | - Hansa Medical, Annual report 2016, (20170426), URL: https://mb.cision.com/Main/1219/2250520/664499.pdf // https://news.cision.com/hansa-biopharma-ab/r/hansa-medical-publishes-the-annual-report-for-2016,c2250520, XP055844501 |
| OPPOSITION | - Hnatowich D J, Et Al, "Pharmacokinetics of 111In-labeled OC-125 antibody in cancer patients compared with the 19-9 antibody", Cancer Research, (19871115), vol. 47, pages 6111 - 6117, XP093066030 |
| OPPOSITION | - Jiannan Cui , Yongkun Zhao , Hualei Wang , Boning Qiu , Zengguo Cao , Qian Li , Yanbo Zhang , Feihu Yan , Hongli Jin , Tiecheng Wang , Weiyang Sun , Na Feng , Yuwei Gao , Jing Sun , Yanqun Wang , Stanley Perlman , Jincun Zhao , Songtao Yang , Xianzhu Xia, "Equine Immunoglobulin and Equine Neutralizing F(ab')2 Protect Mice from West Nile Virus Infection", Viruses, (20161218), vol. 8, no. 12, doi:10.3390/v8120332, pages 1 - 11, XP093066028 |
| OPPOSITION | - MANNO CATHERINE S, ET AL, "Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response.", Nature Medicine, Nature Publishing Group US, New York, New York, (20060301), vol. 12, no. 3, ISSN 1078-8956, pages 342 - 347, XP002578131 |
| OPPOSITION | - M Bazin-Redureau , S Pepin, G Hong, M Debray, J M Scherrmann, "Interspecies scaling of clearance and volume of distribution for horse antivenom F(ab')2", Toxicology and Applied Pharmacology, (19980101), vol. 150, no. 2, doi:10.1006/taap.1997.8363, pages 295 - 300, XP093066031 |
| OPPOSITION | - Mccullough K C, Crowther J R, Butcher R N, Carpenter W C, Brocchi E, Capucci L, De Simone F, "Immune protection against foot-and-mouth disease virus studied using virus-neutralizing and non-neutralizing concentrations of monoclonal antibodies", Cancer research, Wiley-Blackwell Publishing Ltd., GB, GB , (19860701), vol. 58, no. 3, ISSN 0019-2805, pages 421 - 428, XP093129840 |
| OPPOSITION | - PARHAM P., "ON THE FRAGMENTATION OF MONOCLONAL IGG1, IGG2A, AND IGG2B FROM BALB/C MICE.", Journal of Immunology, Williams & Wilkins, (19831201), vol. 131., no. 06., ISSN 0022-1767, pages 2895 - 2902., XP002014406 |
| OPPOSITION | - Terasaki, P.I. Cai, J., "Humoral theory of transplantation: further evidence", Current Opinion in Immunology, ELSEVIER, OXFORD., GB, GB , (20051001), vol. 17, no. 5, ISSN 0952-7915, pages 541 - 545, XP005045065 |
| OPPOSITION | - WANG W et al., "Prediction of Human Clearance of Therapeutic Proteins: Simple Allometric Scaling Method Revisited", Biopharm Drug Dispos, (20100408), vol. 31, no. 4, doi:10.1002/bdd.708, pages 253 - 263, XP071467019 |
| OPPOSITION | - Weirong Wang; Thomayant Prueksaritanont, "Prediction of human clearance of therapeutic proteins: simple allometric scaling method revisited", Biopharm Drug Dispos, US , (20100408), vol. 31, no. 4, doi:10.1002/bdd.708, ISSN 0142-2782, pages 253 - 263, XP071467019 |
| OPPOSITION | - Murphy Samuel L., Li Hojun, Mingozzi Federico, Sabatino Denise E., Hui Daniel J., Edmonson Shyrie A., High Katherine A., "Diverse IgG subclass responses to adeno‐associated virus infection and vector administration", JOURNAL OF MEDICAL VIROLOGY, John Wiley & Sons, Inc., US, US , (20090101), vol. 81, no. 1, doi:10.1002/jmv.21360, ISSN 0146-6615, pages 65 - 74, XP093105454 |
| OPPOSITION | - Murphy Samuel L., Li Hojun, Mingozzi Federico, Sabatino Denise E., Hui Daniel J., Edmonson Shyrie A., High Katherine A., "Diverse IgG subclass responses to adeno‐associated virus infection and vector administration", Journal of Medical Virology, US , (20090101), vol. 81, no. 1, doi:10.1002/jmv.21360, ISSN 0146-6615, pages 65 - 74, XP093105454 |
| OPPOSITION | - Evelyn D Lobo , Ryan J Hansen , Joseph P Balthasar, "Antibody pharmacokinetics and pharmacodynamics", Journal of Pharmaceutical Sciences, US , (20041101), vol. 93, no. 11, doi:10.1002/jps.20178, ISSN 0022-3549, pages 2645 - 2668, XP002403674 |
| OPPOSITION | - LOBO ED et al., "Antibody pharmacokinetics and pharmacodynamics", J Pharm Sci, (20041100), vol. 93, no. 11, doi:10.1002/jps.20178, pages 2645 - 68, XP002403674 |
| OPPOSITION | - Michaels Paul J., Fishbein Michael C., Colvin Robert B., "Humoral rejection of human organ transplants", SPRINGER SEMINAR IN IMMUNOPATHOLOGY., SPRINGER VERLAG., DE, DE , (20030901), vol. 25, no. 2, doi:10.1007/s00281-003-0139-x, ISSN 0344-4325, pages 119 - 140, XP093259358 |
| OPPOSITION | - Li Zhe; Krippendorff Ben-Fillippo; Shah Dhaval K., "Influence of Molecular size on the clearance of antibody fragments", Environmental Science and Pollution Research, Springer Berlin Heidelberg, Berlin/Heidelberg, Berlin/Heidelberg, (20170705), vol. 34, no. 10, doi:10.1007/s11095-017-2219-y, ISSN 0724-8741, pages 2131 - 2141, XP036310023 |
| OPPOSITION | - Zhao Zhongpeng, Fan Chuanbo, Duan Yueqiang, Zhang Liangyan, Li Min, Yang Xiaolan, Li Ruisheng, Yang Penghui, Wang Xiliang, "Protection from infection with influenza A H7N9 virus in a mouse model by equine neutralizing F(ab′)2", International Immunopharmacology, NL , (20141101), vol. 23, no. 1, doi:10.1016/j.intimp.2014.08.019, ISSN 1567-5769, pages 134 - 138, XP093105451 |
| OPPOSITION | - Nimmerjahn Falk; Gordan Sina; Lux Anja, "FcγR dependent mechanisms of cytotoxic, agonistic, and neutralizing antibody activities", Trends in immunology, GB , (20150513), vol. 36, no. 6, doi:10.1016/j.it.2015.04.005, ISSN 1471-4906, pages 325 - 336, XP029611604 |
| OPPOSITION | - Saadi Soheyla et al, "Pathways to Acute Humoral Rejection", The American Journal of Pathology, Elsevier Inc., US, US , (20040301), vol. 164, no. 3, doi:10.1016/S0002-9440(10)63194-X, ISSN 0002-9440, pages 1073 - 1080, XP093259356 |
| OPPOSITION | - Céline Bal, Cécile H Herbreteau, Philippe Buchy, Sareth Rith, Masliza Zaid, William Kristanto, Velda Han, Charlotte Reynaud, Patrick Granjard, Bertrand Lépine, Caroline Durand, Paul A Tambyah, "Safety, potential efficacy, and pharmacokinetics of specific polyclonal immunoglobulin F(ab')2 fragments against avian influenza A (H5N1) in healthy volunteers: a single-centre, randomised, double-blind, placebo-controlled, phase 1 study", The Lancet Infectious Diseases, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20150301), vol. 15, no. 3, doi:10.1016/S1473-3099(14)71072-2, ISSN 1473-3099, pages 285 - 292, XP055374894 |
| OPPOSITION | - Carmela Zincarelli, Stephen Soltys, Giuseppe Rengo, Joseph E Rabinowitz, "Analysis of AAV Serotypes 1-9 Mediated Gene Expression and Tropism in Mice After Systemic Injection", Molecular Therapy, US , (20080601), vol. 16, no. 6, doi:10.1038/mt.2008.76, ISSN 1525-0016, pages 1073 - 1080, XP055338752 |
| OPPOSITION | - MONTEILHET V et al., "A 10 Patient Case Report on the Impact of Plasmapheresis Upon Neutralizing Factors Against Adeno-associated Virus (AAV) Types 1, 2, 6, and 8", Mol Ther, (20111100), vol. 19, no. 11, doi:10.1038/mt.2011.108, pages 2084 - 2091, XP055367781 |
| OPPOSITION | - Virginie Monteilhet, Samir Saheb, Sylvie Boutin, Christian Leborgne, Philippe Veron, Marie-Françoise Montus, Philippe Moullier, Olivier Benveniste, Carole Masurier, "A 10 Patient Case Report on the Impact of Plasmapheresis Upon Neutralizing Factors Against Adeno-associated Virus (AAV) Types 1, 2, 6, and 8", Molecular Therapy, Elsevier Inc., US, US , (20111101), vol. 19, no. 11, doi:10.1038/mt.2011.108, ISSN 1525-0016, pages 2084 - 2091, XP055367781 |
| OPPOSITION | - Virginie Monteilhet, Samir Saheb, Sylvie Boutin, Christian Leborgne, Philippe Veron, Marie-Françoise Montus, Philippe Moullier, Olivier Benveniste, Carole Masurier, "A 10 Patient Case Report on the Impact of Plasmapheresis Upon Neutralizing Factors Against Adeno-associated Virus (AAV) Types 1, 2, 6, and 8", Molecular Therapy, US , (20111101), vol. 19, no. 11, doi:10.1038/mt.2011.108, ISSN 1525-0016, pages 2084 - 2091, XP055367781 |
| OPPOSITION | - Lg Chicoine, Cl Montgomery, Wg Bremer, Km Shontz, Da Griffin, Kn Heller, S Lewis, V Malik, We Grose, Cj Shilling, Kj Campbell, Tj Preston, Bd Coley, Pt Martin, Cm Walker, Kr Clark, Z Sahenk, Jr Mendell, Lr Rodino-Klapac, "Plasmapheresis Eliminates the Negative Impact of AAV Antibodies on Microdystrophin Gene Expression Following Vascular Delivery", Molecular Therapy, Elsevier Inc., US, US , (20140201), vol. 22, no. 2, doi:10.1038/mt.2013.244, ISSN 1525-0016, pages 338 - 347, XP055367763 |
| OPPOSITION | - Marasco Wayne A; Sui Jianhua, "The growth and potential of human antiviral monoclonal antibody therapeutics", Nature Biotechnology, Nature Publishing Group US, New York, New York, (20071201), vol. 25, no. 12, doi:10.1038/nbt1363, ISSN 1087-0156, pages 1421 - 1434, XP037065883 |
| OPPOSITION | - Dan Wang, "Adeno-associated virus vector as a platform for gene therapy delivery", Nature Reviews Drug Discovery, GB , (20190501), vol. 18, no. 5, doi:10.1038/s41573-019-0012-9, ISSN 1474-1776, pages 1 - 61, XP093166191 |
| OPPOSITION | - JORDAN et al., "IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation", N Engl J Med, (20170803), vol. 377, no. 5, doi:10.1056/NEJMoa1612567, pages 442 - 453, XP055527161 |
| OPPOSITION | - Jordan Stanley C., Lorant Tomas, Choi Jua, Kjellman Christian, Winstedt Lena, Bengtsson Mats, Zhang Xiaohai, Eich Torsten, Toyoda Mieko, Eriksson Britt-Marie, Ge Shili, Peng Alice, Järnum Sofia, Wood Kathryn J., Lundgren Torbjorn, Wennberg Lars, Bäckman Lars, Larsson Erik, Villicana Rafael, Kahwaji Joe, Louie Sabrina, Kang Alexis, Haas Mark, Nast Cynthia, Vo Ashley, Tufveson Gunnar, "APPENDIX: IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation", The New England journal of medicine, Massachusetts Medical Society, US, US , (20170803), vol. 377, no. 5, doi:10.1056/NEJMoa1612567, ISSN 0028-4793, pages 1 - 8, XP055844310 |
| OPPOSITION | - Jordan Stanley C., Lorant Tomas, Choi Jua, Kjellman Christian, Winstedt Lena, Bengtsson Mats, Zhang Xiaohai, Eich Torsten, Toyoda Mieko, Eriksson Britt-Marie, Ge Shili, Peng Alice, Järnum Sofia, Wood Kathryn J., Lundgren Torbjorn, Wennberg Lars, Bäckman Lars, Larsson Erik, Villicana Rafael, Kahwaji Joe, Louie Sabrina, Kang Alexis, Haas Mark, Nast Cynthia, Vo Ashley, Tufveson Gunnar, "IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation", The New England journal of medicine, Massachusetts Medical Society, US, US , (20170803), vol. 377, no. 5, doi:10.1056/NEJMoa1612567, ISSN 0028-4793, pages 442 - 453, XP093025301 |
| OPPOSITION | - Jordan Stanley C., Lorant Tomas, Choi Jua, Kjellman Christian, Winstedt Lena, Bengtsson Mats, Zhang Xiaohai, Eich Torsten, Toyoda Mieko, Eriksson Britt-Marie, Ge Shili, Peng Alice, Järnum Sofia, Wood Kathryn J., Lundgren Torbjorn, Wennberg Lars, Bäckman Lars, Larsson Erik, Villicana Rafael, Kahwaji Joe, Louie Sabrina, Kang Alexis, Haas Mark, Nast Cynthia, Vo Ashley, Tufveson Gunnar, "IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation", The New England journal of medicine, US , (20170803), vol. 377, no. 5, doi:10.1056/NEJMoa1612567, ISSN 0028-4793, pages 442 - 453, XP093025301 |
| OPPOSITION | - S.C. Jordan et al., "IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation", The New England Journal of Medicine, (20170803), vol. 377, doi:10.1056/NEJMoa1612567, XP055844310 |
| OPPOSITION | - R.J. Brezski et al., "Tumor-associated and microbial proteases compromise host IgG effector functions by a single cleavage proximal to the hinge", PNAS, (20091020), vol. 106, doi:10.1073/pnas.0904174106, XP055058828 |
| OPPOSITION | - Christofer A. Q. Karlsson, Sofia Järnum, Lena Winstedt, Christian Kjellman, Lars Björck, Adam Linder, Johan A. Malmström, "Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS", Molecular & Cellular Proteomics, American Society for Biochemistry and Molecular Biology, US, US , (20180601), vol. 17, no. 6, doi:10.1074/mcp.RA117.000525, ISSN 1535-9476, pages 1097 - 1111, XP055679832 |
| OPPOSITION | - Karlsson Christofer, Sofia Jarnum, Lena Winstedt, Christian Kjellman, Lars Bjorck, Adam Linder, Johan Malmstrom, "Excerpt Supplementary Material: Supplementary Tables S3: Streptococcus pyogenes infection and the human proteome with a special focus on the lgG-cleaving enzyme Ides", Molecular & Cellular Proteomics, American Society for Biochemistry and Molecular Biology, US, US , (20180601), vol. 17, no. 6, doi:10.1074/mcp.RA117.000525, ISSN 1535-9476, pages 1 - 5, XP093121015 |
| OPPOSITION | - LOUIS JEUNE, VEDELL et al., "Pre-existing Anti-Adeno-Associated Virus Antibodies as a Challenge in AAV Gene Therapy", Human gene therapy methods, (20130400), vol. 24, no. 2, doi:10.1089/hgtb.2012.243, pages 59 - 67, XP055563307 |
| OPPOSITION | - Vedell Louis Jeune, Jakob A. Joergensen, Roger J. Hajjar, Thomas Weber, "Pre-existing Anti-Adeno-Associated Virus Antibodies as a Challenge in AAV Gene Therapy", Human Gene Therapy Methods, (20130401), vol. 24, no. 2, doi:10.1089/hgtb.2012.243, ISSN 1946-6536, pages 59 - 67, XP055563307 |
| OPPOSITION | - Amine Meliani, Christian Leborgne, Sabrina Triffault, Laurence Jeanson-Leh, Philippe Veron, Federico Mingozzi, "Determination of Anti-Adeno-Associated Virus Vector Neutralizing Antibody Titer with an In Vitro Reporter System", Human Gene Therapy Methods, (20150401), vol. 26, no. 2, doi:10.1089/hgtb.2015.037, ISSN 1946-6536, pages 45 - 53, XP055547191 |
| OPPOSITION | - MELIANI et al., "Determination of Anti-Adeno-Associated Virus Vector Neutralizing Antibody Titer with an In Vitro Reporter System", Hum Gene Ther Methods, (20150400), vol. 26, no. 2, doi:10.1089/hgtb.2015.037, pages 45 - 53, XP055547191 |
| OPPOSITION | - BOUTIN et al., "Prevalence of Serum IgG and Neutralizing Factors Against Adeno-Associated Virus (AAV) Types 1, 2, 5, 6, 8, and 9 in the Healthy Population: Implications for Gene Therapy Using AAV Vectors", HUMAN GENE THERAPY, (20100600), vol. 21, no. 6, doi:10.1089/hum.2009.182, pages 704 - 12, XP055172076 |
| OPPOSITION | - Sylvie Boutin, Virginie Monteilhet, Philippe Veron, Christian Leborgne, Olivier Benveniste, Marie Françoise Montus, Carole Masurier, "Prevalence of Serum IgG and Neutralizing Factors Against Adeno-Associated Virus (AAV) Types 1, 2, 5, 6, 8, and 9 in the Healthy Population: Implications for Gene Therapy Using AAV Vectors", Human Gene Therapy, (20100601), vol. 21, no. 6, doi:10.1089/hum.2009.182, ISSN 10430342, pages 704 - 712, XP055172056 |
| OPPOSITION | - Sylvie Boutin, Virginie Monteilhet, Philippe Veron, Christian Leborgne, Olivier Benveniste, Marie Françoise Montus, Carole Masurier, "Prevalence of Serum IgG and Neutralizing Factors Against Adeno-Associated Virus (AAV) Types 1, 2, 5, 6, 8, and 9 in the Healthy Population: Implications for Gene Therapy Using AAV Vectors", Human Gene Therapy, Mary Ann Liebert, (20100601), vol. 21, no. 6, doi:10.1089/hum.2009.182, ISSN 10430342, pages 704 - 712, XP055172056 |
| OPPOSITION | - Céline Vandamme, Oumeya Adjali, Federico Mingozzi, "Unraveling the Complex Story of Immune Responses to AAV Vectors Trial After Trial", Human gene therapy, GB , (20171101), vol. 28, no. 11, doi:10.1089/hum.2017.150, ISSN 1043-0342, pages 1061 - 1074, XP055738047 |
| OPPOSITION | - PAWEL-RAMMINGEN U et al., "IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G", EMBO J, (20020205), vol. 21, no. 7, doi:10.1093/emboj/21.7.1607, pages 1607 - 1615, XP002243548 |
| OPPOSITION | - PAWEL-RAMMINGEN VON U, JOHANSSON B P , BJOERCK L, "IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G.", The EMBO journal / European Molecular Biology Organization, IRL Press, Oxford, Oxford , (20020401), vol. 21, no. 7, doi:10.1093/emboj/21.7.1607, ISSN 0261-4189, pages 1607 - 1615, XP002243548 |
| OPPOSITION | - Pawel-Rammingen Von U , Johansson B P , Bjoerck L, "IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G.", The EMBO journal, Oxford , (20020402), vol. 21, no. 7, doi:10.1093/emboj/21.7.1607, ISSN 0261-4189, pages 1607 - 1615, XP002243548 |
| OPPOSITION | - U. Von Pawel-Rammingen et al., "IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G", EMBO Journal, (20020402), vol. 21, doi:10.1093/emboj/21.7.1607, XP002243548 |
| OPPOSITION | - Raimund J. Ober, Caius G. Radu , Victor Ghetie , E. Sally Ward, "Differences in promiscuity for antibody-FcRn interactions across species: Implications for therapeutic antibodies", International Immunology, GB , (20011201), vol. 13, no. 12, doi:10.1093/intimm/13.12.1551, ISSN 0953-8178, pages 1551 - 1559, XP002526759 |
| OPPOSITION | - Harbison Carole E., Weichert Wendy S., Gurda Brittney L., Chiorini John A., Agbandje-Mckenna Mavis, Parrish Colin R., "Examining the cross-reactivity and neutralization mechanisms of a panel of mAbs against adeno-associated virus serotypes 1 and 5", Journal of General Virology, Society for General Microbiology, (20120201), vol. 93, no. 2, doi:10.1099/vir.0.035113-0, ISSN 0022-1317, pages 347 - 355, XP055905353 |
| OPPOSITION | - LORANT T et al., "Safety, immunogenicity, pharmacokinetics, and efficacy of degradation of anti-HLA antibodies by IdeS (imlifidase) in chronic kidney disease patients", Am J Transplant, (20180417), vol. 18, no. 11, doi:10.1111/ajt.14733, pages 2752 - 2762, XP055765129 |
| OPPOSITION | - Tomas Lorant; Mats Bengtsson; Torsten Eich; Britt‐Marie Eriksson; Lena Winstedt; Sofia Järnum; Yvonne Stenberg; Anna‐Karin Robertson; Kristina Mosén; Lars Björck; Lars Bäckman; Erik Larsson; Kathryn Wood; Gunnar Tufveson; Christian Kjellman, "Safety, immunogenicity, pharmacokinetics, and efficacy of degradation of anti‐HLA antibodies by IdeS (imlifidase) in chronic kidney disease patients", American journal of transplantation, BLACKWELL MUNKSGAARD, DK, DK , (20180417), vol. 18, no. 11, doi:10.1111/ajt.14733, ISSN 1600-6135, pages 2752 - 2762, XP072343446 |
| OPPOSITION | - Tomas Lorant, Mats Bengtsson, Torsten Eich, Britt-Marie Eriksson, Lena Winstedt, Sofia Järnum, Yvonne Stenberg, Anna-Karin Robertson, Kristina Mosén, Lars Björck, Lars Bäckman, Erik Larsson, Kathryn Wood, Gunnar Tufveson, Christian Kjellman, "Safety, immunogenicity, pharmacokinetics, and efficacy of degradation of anti-HLA antibodies by IdeS (imlifidase) in chronic kidney disease patients", American journal of transplantation, DK , (20181101), vol. 18, no. 11, doi:10.1111/ajt.14733, ISSN 1600-6135, pages 2752 - 2762, XP055765129 |
| OPPOSITION | - Tomas Lorant; Mats Bengtsson; Torsten Eich; Britt-Marie Eriksson; Lena Winstedt; Sofia Järnum; Yvonne Stenberg; Anna-Karin Robertson; Kristina Mosén; Lars Björck; Lars Bäckman; Erik Larsson; Kathryn Wood; Gunnar Tufveson; Christian Kjellman, "Safety, immunogenicity, pharmacokinetics, and efficacy of degradation of anti-HLA antibodies by IdeS (imlifidase) in chronic kidney disease patients", American journal of transplantation, DK , (20181101), vol. 18, no. 11, doi:10.1111/ajt.14733, ISSN 1600-6135, pages 2752 - 2762, XP055765129 |
| OPPOSITION | - Whitehead Michael, Osborne Andrew, Yu‐wai‐man Patrick, Martin Keith, "Humoral immune responses to AAV gene therapy in the ocular compartment ", Biological Reviews, Wiley-Blackwell Publishing Ltd., GB, GB , (20210801), vol. 96, no. 4, doi:10.1111/brv.12718, ISSN 1464-7931, pages 1616 - 1644, XP093129838 |
| OPPOSITION | - MARTINEZ M et al., "Interspecies allometric scaling: prediction of clearance in large animal species: Part II: mathematical considerations", J Vet Pharmacol Ther, (20061000), vol. 29, no. 5, doi:10.1111/j.1365-2885.2006.00787.x, pages 425 - 432, XP055907693 |
| OPPOSITION | - Martinez M., Mahmood I., Hunter R. P., "Interspecies allometric scaling: prediction of clearance in large animal species: Part II: mathematical considerations", Journal of Veterinary Pharmacology and Therapeutics, GB , (20061001), vol. 29, no. 5, doi:10.1111/j.1365-2885.2006.00787.x, ISSN 0140-7783, pages 425 - 432, XP055907693 |
| OPPOSITION | - Mingozzi F., Anguela X. M., Pavani G., Chen Y., Davidson R. J., Hui D. J., Yazicioglu M., Elkouby L., Hinderer C. J., Faella A., Howard C., Tai A., Podsakoff G. M., Zhou S., Basner-Tschakarjan E., Wright J. F., High K. A., "Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys", SCIENCE TRANSLATIONAL MEDICINE, American Association for the Advancement of Science, (20130717), vol. 5, no. 194, doi:10.1126/scitranslmed.3005795, ISSN 1946-6234, pages 194ra92 - 194ra92, XP055811011 |
| OPPOSITION | - Wikström M B, Dahlén G, Kaijser B, Nygren H, "Degradation of human immunoglobulins by proteases from Streptococcus pneumoniae obtained from various human sources", Infection and immunity, American Society for Microbiology, US, US , (19840401), vol. 44, no. 1, doi:10.1128/iai.44.1.33-37.1984, ISSN 0019-9567, pages 33 - 37, XP093091644 |
| OPPOSITION | - Wikström M B, Dahlén G, Kaijser B, Nygren H, "Degradation of human immunoglobulins by proteases from Streptococcus pneumoniae obtained from various human sources", Infection and immunity, US , (19840401), vol. 44, no. 1, doi:10.1128/iai.44.1.33-37.1984, ISSN 0019-9567, pages 33 - 37, XP093091644 |
| OPPOSITION | - JARNUM S et al., "Enzymatic Inactivation of Endogenous IgG by IdeS Enhances Therapeutic Antibody Efficacy", Mol Cancer Ther, (20170522), vol. 16, no. 9, doi:10.1158/1535-7163.MCT-17-0108, pages 1887 - 1897, XP055911648 |
| OPPOSITION | - Järnum Sofia, Runström Anna, Bockermann Robert, Winstedt Lena, Crispin Max, Kjellman Christian, "Enzymatic Inactivation of Endogenous IgG by IdeS Enhances Therapeutic Antibody Efficacy", Molecular Cancer Therapeutics, American Association for Cancer Research, US, US , (20170901), vol. 16, no. 9, doi:10.1158/1535-7163.MCT-17-0108, ISSN 1535-7163, pages 1887 - 1897, XP055911648 |
| OPPOSITION | - Järnum Sofia, Runström Anna, Bockermann Robert, Winstedt Lena, Crispin Max, Kjellman Christian, "Enzymatic Inactivation of Endogenous IgG by IdeS Enhances Therapeutic Antibody Efficacy", Molecular Cancer Therapeutics, US , (20170901), vol. 16, no. 9, doi:10.1158/1535-7163.MCT-17-0108, ISSN 1535-7163, pages 1887 - 1897, XP055911648 |
| OPPOSITION | - PAWEL-RAMMINGEN U. et al., "Streptococcal IdeS and Its Impact on Immune Response and Inflammation", J Innate Immun, (20120117), vol. 4, no. 2, doi:10.1159/000332940, pages 132 - 140, XP055830237 |
| OPPOSITION | - U. Von Pawel-Rammingen null, "Streptococcal IdeS and Its Impact on Immune Response and Inflammation", Journal of Innate Immunity, (20120117), vol. 4, doi:10.1159/000332940, XP055830237 |
| OPPOSITION | - Von Pawel-Rammingen Ulrich, "Streptococcal IdeS and Its Impact on Immune Response and Inflammation", Journal of innate immunity, CH , (20120101), vol. 4, no. 2, doi:10.1159/000332940, ISSN 1662-811X, pages 132 - 140, XP055830237 |
| OPPOSITION | - Pahwa S G, Pahwa R N, Good R A, "Decreased in vitro humoral immune responses in aged humans.", The Journal of Clinical Investigation, GB , (19810401), vol. 67, no. 4, doi:10.1172/JCI110122, ISSN 0021-9738, pages 1094 - 1102, XP093105434 |
| OPPOSITION | - C. D. Scallan, Haiyan Jiang, Tongyao Liu, Susannah Patarroyo White, Jurg Sommer, Shangzhen Zhou, Linda Couto, Glenn Pierce, "Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice", Blood, (20060301), vol. 107, no. 5, doi:10.1182/blood-2005-08-3229, ISSN 00064971, pages 1810 - 1817, XP055070106 |
| OPPOSITION | - Scallan Ciaran D., Jiang Haiyan, Liu Tongyao, Patarroyo-White Susannah, Sommer Jurg M., Zhou Shangzhen, Couto Linda B., Pierce Glenn F., "Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice", Blood, American Society of Hematology, US, US , (20060301), vol. 107, no. 5, doi:10.1182/blood-2005-08-3229, ISSN 0006-4971, pages 1810 - 1817, XP055938301 |
| OPPOSITION | - H. Jiang, L. B. Couto, S. Patarroyo-White, T. Liu, D. Nagy, J. A. Vargas, S. Zhou, C. D. Scallan, J. Sommer, S. Vijay, F. Mingozzi, K. A. High, G. F. Pierce, "Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy", Blood, (20061115), vol. 108, no. 10, doi:10.1182/blood-2006-04-017913, ISSN 00064971, pages 3321 - 3328, XP055175201 |
| OPPOSITION | - F. Mingozzi, K. A. High, "Immune responses to AAV vectors: overcoming barriers to successful gene therapy", Blood, (20130704), vol. 122, no. 1, doi:10.1182/blood-2013-01-306647, ISSN 00064971, pages 23 - 36, XP055175008 |
| OPPOSITION | - MINGOZZI et al., "Immune responses to AAV vectors: overcoming barriers to successful gene therapy", Blood, (20130417), vol. 122, no. 1, doi:10.1182/blood-2013-01-306647, pages 23 - 36, XP055175008 |
| OPPOSITION | - Winstedt Lena; Järnum Sofia; Nordahl Emma Andersson; Olsson Andreas; Runström Anna; Bockermann Robert; Karlsson Christofer; Malmström Johan; Palmgren Gabriella Samuelsson; Malmqvist Ulf; Björck Lars; Kjellman Christian, "Complete Removal of Extracellular IgG Antibodies in a Randomized Dose-Escalation Phase I Study with the Bacterial Enzyme IdeS - A Novel Therapeutic Opportunity", PLOS ONE, (20150715), vol. 10, no. 7, doi:10.1371/journal.pone.0132011, pages 1 - 20, XP055842658 |
| OPPOSITION | - Winstedt Lena, Järnum Sofia, Nordahl Emma, Olsson Andreas, Runström Anna, Bockermann Robert, Karlsson Christofer, Malmström Johan, Palmgren Gabriella, Malmqvist Ulf, Björck Lars, Kjellman Christian, Glod John, "Complete Removal of Extracellular IgG Antibodies in a Randomized Dose-Escalation Phase I Study with the Bacterial Enzyme IdeS - A Novel Therapeutic Opportunity", PLOS ONE, Public Library of Science (PLoS), (20150715), vol. 10, no. 7, doi:10.1371/journal.pone.0132011, page e0132011, XP093025342 |
| OPPOSITION | - WINSTEDT L et al., "Complete Removal of Extracellular IgG Antibodies in a Randomized Dose-Escalation Phase I Study with the Bacterial Enzyme IdeS -A Novel Therapeutic Opportunity", PLoS One, (20150715), vol. 10, no. 7, doi:10.1371/journal.pone.0132011, page e0132011, XP055842658 |
| OPPOSITION | - MAHMOOD I et al., "Interspecies Scaling of Antibody-Drug Conjugates (ADC) for the Prediction of Human Clearance", Antibodies (Basel, (20210107), vol. 10, no. 1, doi:10.3390/antib10010001, page 1, XP055907685 |
| OPPOSITION | - Mahmood Iftekhar, "Interspecies Scaling of Antibody-Drug Conjugates (ADC) for the Prediction of Human Clearance", Antibodies, (20210101), vol. 10, no. 1, doi:10.3390/antib10010001, pages 1 - 13, XP055907685 |
| OPPOSITION | - Randall J. Brezski, Jordan, Robert E., "Cleavage of IgGs by proteases associated with invasive diseases ", Landes Bioscience, doi:10.4161/mabs.2.3.11780, (20100501), pages 212 - 220, Landes Bioscience, URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881249/pdf/mabs0203_0212.pdf, (20141216), XP055158873 |
| OTHER | - Bazin-Redureau Martine I., Renard, Catherine B.; Scherrmann, Jean-Michel G., "Pharmacokinetics of heterologous and homologous immunoglobulin G, F(ab')2 and Fab after intravenous administration in the rat", J. Pharm. Pharmacol., (19970101), vol. 49, no. 16, pages 277 - 281, XP055907636 |
| OTHER | - Covell David G, Barbet Jacques, Holton Oscar D, Black Christopher D V, Parker R J, Weinstein John N, "Pharmacokinetics of Monoclonal Immunoglobulin G1, F(ab')2, and Fab' in Mice", CANCER RESEARCH, (19860801), vol. 46, pages 3969 - 3978, XP055907644 |
| OTHER | - Weirong Wang; Thomayant Prueksaritanont, "Prediction of human clearance of therapeutic proteins: simple allometric scaling method revisited", BIOPHARMACEUTICS AND DRUG DISPOSITION, US , (20100408), vol. 31, no. 4, doi:10.1002/bdd.708, ISSN 0142-2782, pages 253 - 263, XP071467019 |
| OTHER | - Martinez M., Mahmood I., Hunter R. P., "Interspecies allometric scaling: prediction of clearance in large animal species: Part II: mathematical considerations", JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, GB , (20061001), vol. 29, no. 5, doi:10.1111/j.1365-2885.2006.00787.x, ISSN 0140-7783, pages 425 - 432, XP055907693 |
| OTHER | - Mahmood Iftekhar, "Interspecies Scaling of Antibody-Drug Conjugates (ADC) for the Prediction of Human Clearance", Antibodies, (20210101), vol. 10, no. 1, doi:10.3390/antib10010001, pages 1 - 13, XP055907685 |
