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Compositions And Methods For Increasing Or Enhancing Transduction Of Gene Therapy Vectors And For Removing Or Reducing Immunoglobulins - EP3768304

EP3768304

GENETHON
Application Number
EP19740384A
Filing Date
Jul 17, 2019
Status
Granted And Under Opposition
Sep 9, 2022
Grant Date
Oct 12, 2022
External Links
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The patent EP3768304B1 was granted to Genethon on Oct 12, 2022 following the initial filing on Jul 17, 2019 under the application number EP19740384A . The current legal status of the patent is Granted And Under Opposition.

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Patent Family

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HANSA BIOPHARMAJul 12, 2023ADMISSIBLE
SANOFIJul 12, 2023ADMISSIBLE
NEDERLANDSCH OCTROOIBUREAUJul 11, 2023ADMISSIBLE
MICHALSKI HUTTERMANN & PARTNER PATENTANWALTE MBBJul 10, 2023ADMISSIBLE
BAYERJun 23, 2023ADMISSIBLE
GATESIPApr 6, 2023ADMISSIBLE

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Patent citations refer to prior patents cited during different phases such as opposition or international search.

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OPPOSITION- Jordan Stanley C., Lorant Tomas, Choi Jua, Kjellman Christian, Winstedt Lena, Bengtsson Mats, Zhang Xiaohai, Eich Torsten, Toyoda Mieko, Eriksson Britt-Marie, Ge Shili, Peng Alice, Järnum Sofia, Wood Kathryn J., Lundgren Torbjorn, Wennberg Lars, Bäckman Lars, Larsson Erik, Villicana Rafael, Kahwaji Joe, Louie Sabrina, Kang Alexis, Haas Mark, Nast Cynthia, Vo Ashley, Tufveson Gunnar, "IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation", The New England journal of medicine, Massachusetts Medical Society, US, US , (20170803), vol. 377, no. 5, doi:10.1056/NEJMoa1612567, ISSN 0028-4793, pages 442 - 453, XP093025301
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OPPOSITION- Amine Meliani, Christian Leborgne, Sabrina Triffault, Laurence Jeanson-Leh, Philippe Veron, Federico Mingozzi, "Determination of Anti-Adeno-Associated Virus Vector Neutralizing Antibody Titer with an In Vitro Reporter System", Human Gene Therapy Methods, (20150401), vol. 26, no. 2, doi:10.1089/hgtb.2015.037, ISSN 1946-6536, pages 45 - 53, XP055547191
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OPPOSITION- Tomas Lorant; Mats Bengtsson; Torsten Eich; Britt-Marie Eriksson; Lena Winstedt; Sofia Järnum; Yvonne Stenberg; Anna-Karin Robertson; Kristina Mosén; Lars Björck; Lars Bäckman; Erik Larsson; Kathryn Wood; Gunnar Tufveson; Christian Kjellman, "Safety, immunogenicity, pharmacokinetics, and efficacy of degradation of anti-HLA antibodies by IdeS (imlifidase) in chronic kidney disease patients", American journal of transplantation, DK , (20181101), vol. 18, no. 11, doi:10.1111/ajt.14733, ISSN 1600-6135, pages 2752 - 2762, XP055765129
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OPPOSITION- C. D. Scallan, Haiyan Jiang, Tongyao Liu, Susannah Patarroyo White, Jurg Sommer, Shangzhen Zhou, Linda Couto, Glenn Pierce, "Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice", Blood, (20060301), vol. 107, no. 5, doi:10.1182/blood-2005-08-3229, ISSN 00064971, pages 1810 - 1817, XP055070106
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OPPOSITION- Winstedt Lena; Järnum Sofia; Nordahl Emma Andersson; Olsson Andreas; Runström Anna; Bockermann Robert; Karlsson Christofer; Malmström Johan; Palmgren Gabriella Samuelsson; Malmqvist Ulf; Björck Lars; Kjellman Christian, "Complete Removal of Extracellular IgG Antibodies in a Randomized Dose-Escalation Phase I Study with the Bacterial Enzyme IdeS - A Novel Therapeutic Opportunity", PLOS ONE, (20150715), vol. 10, no. 7, doi:10.1371/journal.pone.0132011, pages 1 - 20, XP055842658
OPPOSITION- Winstedt Lena, Järnum Sofia, Nordahl Emma, Olsson Andreas, Runström Anna, Bockermann Robert, Karlsson Christofer, Malmström Johan, Palmgren Gabriella, Malmqvist Ulf, Björck Lars, Kjellman Christian, Glod John, "Complete Removal of Extracellular IgG Antibodies in a Randomized Dose-Escalation Phase I Study with the Bacterial Enzyme IdeS - A Novel Therapeutic Opportunity", PLOS ONE, Public Library of Science (PLoS), (20150715), vol. 10, no. 7, doi:10.1371/journal.pone.0132011, page e0132011, XP093025342
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