| EXAMINATION | - XP93169919, XP093169919 | - |
| EXAMINATION | - XP93169922, XP093169922 | - |
| EXAMINATION | - Lovorka Grgurevic, "Recombinant Human Bone Morphogenetic Protein 6 Delivered Within Autologous Blood Coagulum Restores Critical Size Segmental Defects of Ulna in Rabbits", JBMR Plus, vol. 3, no. 5, doi:10.1002/jbm4.10085, ISSN 2473-4039, (20181105), URL: https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjbm4.10085, XP093169906 | |
| EXAMINATION | - CATHARINA CHIARI, "Recombinant Human BMP6 Applied Within Autologous Blood Coagulum Accelerates Bone Healing: Randomized Controlled Trial in High Tibial Osteotomy Patients", JOURNAL OF BONE AND MINERAL RESEARCH, US, vol. 35, no. 10, doi:10.1002/jbmr.4107, ISSN 0884-0431, (20200616), pages 1893 - 1903, URL: https://onlinelibrary.wiley.com/doi/full-xml/10.1002/jbmr.4107, XP093169872 | |
| EXAMINATION | - SLOBODAN VUKICEVIC, "Autologous blood coagulum is a physiological carrier for BMP6 to induce new bone formation and promote posterolateral lumbar spine fusion in rabbits", JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, US, vol. 14, no. 1, doi:10.1002/term.2981, ISSN 1932-6254, (20191110), pages 147 - 159, URL: https://onlinelibrary.wiley.com/doi/full-xml/10.1002/term.2981, XP093169900 | |
| EXAMINATION | - Jelena Brkljacic, "Exogenous heparin binds and inhibits bone morphogenetic protein 6 biological activity", INTERNATIONAL ORTHOPEADICS, DE, vol. 37, no. 3, doi:10.1007/s00264-012-1714-3, ISSN 0341-2695, (20130110), pages 529 - 541, URL: http://link.springer.com/article/10.1007/s00264-012-1714-3/fulltext.html, XP093169865 | |
| EXAMINATION | - Slobodan Vukicevic, "The clinical use of bone morphogenetic proteins revisited: a novel biocompatible carrier device OSTEOGROW for bone healing", INTERNATIONAL ORTHOPEADICS, DE, vol. 38, no. 3, doi:10.1007/s00264-013-2201-1, ISSN 0341-2695, (20131219), pages 635 - 647, URL: http://link.springer.com/article/10.1007/s00264-013-2201-1/fulltext.html, XP093169898 | |
| EXAMINATION | - STOKOVIC NIKOLA ET AL, "Synthetic ceramic macroporous blocks as a scaffold in ectopic bone formation induced by recombinant human bone morphogenetic protein 6 within autologous blood coagulum in rats", INTERNATIONAL ORTHOPEADICS, SPRINGER, BERLIN, DE, vol. 45, no. 4, doi:10.1007/S00264-020-04847-9, ISSN 0341-2695, (20201014), pages 1097 - 1107, (20201014), XP037425800 | |
| EXAMINATION | - DURDEVIC DRAGAN ET AL, "A novel autologous bone graft substitute comprised of rhBMP6 blood coagulum as carrier tested in a randomized and controlled Phase I trial in patients with distal radial fractures", BONE, PERGAMON PRESS., OXFORD, GB, vol. 140, doi:10.1016/J.BONE.2020.115551, ISSN 8756-3282, (20200727), (20200727), XP086267598 | |
| EXAMINATION | - VAIDA GLATT, "Biomimetic Hematoma as a Novel Delivery Vehicle for rhBMP-2 to Potentiate the Healing of Nonunions and Bone Defects", JOURNAL OF ORTHOPAEDIC TRAUMA, US, (20231101), vol. 37, no. 11S, doi:10.1097/BOT.0000000000002692, ISSN 0890-5339, pages S33 - S39, XP093169883 | |
| EXAMINATION | - Götz Nowak, "The Ecarin Clotting Time, a Universal Method to Quantify Direct Thrombin Inhibitors", Pathophysiology of Haemost Thrombosis, CH, vol. 33, no. 4, doi:10.1159/000081505, ISSN 1424-8832, (20030101), pages 173 - 183, URL: https://www.karger.com/Article/Pdf/81505, XP093169903 | |
| INTERNATIONAL-SEARCH-REPORT | - VAN ROOY et al., "Platelet hyperactivity and fibrin clot structure in transient ischemic attack individuals in the presence of metabolic syndrome: a microscopy and thromboelastography® study", Cardiovascular Diabetology, (20150000), vol. 14, no. 86, XP021227124 [Y] 1-5, 7-26 * , entire document * | |
| OPPOSITION | - Glatt Vaida, Anna Woloszyk, Kevin Tetsworth, "Mimicking the structure of fracture hematomas using snake venom enzymes for the creation of ex vivo natural designer scaffolds to enhance bone repair", Journal of Limb Lengthening & Reconstruction, (20170701), vol. 3, no. 1, pages S1 - S2, XP093308263 | - |
| OPPOSITION | - Glatt Vaida, Friis Thor, Woloszyk Anna, Masci Paul, Tetsworth Kevin, "P816 Mimicking the structure of fracture hematomas using snake venom enzymes for the creation of an ex vivo natural designer scaffold to enhance bone repair", eCM Meeting Abstracts 2017, Collection 2; TERMIS EU (P816), (20170101), page P816, XP093308267 | - |
| OPPOSITION | - Wang Xin, Friis Thor, Glatt Vaida, Crawford Ross, Xiao Yin, "Structural properties of fracture haematoma: current status and future clinical implications : Structural properties of fracture haematoma", JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, John Wiley & Sons, US, US , (20171001), vol. 11, no. 10, doi:10.1002/term.2190, ISSN 1932-6254, pages 2864 - 2875, XP093308281 | |
| OPPOSITION | - Dumic-Cule Ivo; Peric Mihaela; Kucko Lucija; Grgurevic Lovorka; Pecina Marko; Vukicevic Slobodan, "Bone morphogenetic proteins in fracture repair", INTERNATIONAL ORTHOPEADICS, SPRINGER, BERLIN, DE, DE , (20180915), vol. 42, no. 11, doi:10.1007/s00264-018-4153-y, ISSN 0341-2695, pages 2619 - 2626, XP036613660 | |
| OPPOSITION | - Anna Jonebring; Ute Lange; Elke Bucha; Johanna Deinum; Margareta Elg; Ann Lövgren, "Expression and Characterization of Recombinant Ecarin", Journal of Protein Chemistry, Kluwer Academic Publishers-Plenum Publishers, Ne, Ne , (20120417), vol. 31, no. 5, doi:10.1007/s10930-012-9409-6, ISSN 1573-4943, pages 353 - 358, XP035074605 | |
| OPPOSITION | - Kuber Sampath, "Discovery of bone morphogenetic proteins - Ahistorical perspective", Bone, (2020), vol. 140, doi:10.1016/j.bone.2020.115548, XP086267595 | |
| OPPOSITION | - James Aaron W., Lachaud Gregory, Shen Jia, Asatrian Greg, Nguyen Vi, Zhang Xinli, Ting Kang, Soo Chia, "A Review of the Clinical Side Effects of Bone Morphogenetic Protein-2", Tissue engineering Part B, Mary Ann Liebert, Inc. Publishers, US, US , (20160801), vol. 22, no. 4, doi:10.1089/ten.teb.2015.0357, ISSN 1937-3368, pages 284 - 297, XP093308285 | |
| OPPOSITION | - MANN, "Citrate anticoagulation and the dynamics of thrombin generation", Journal of Thrombosis and Haemostasis, (2007), vol. 5, doi:10.1111/j.1538-7836.2007.02710.x, XP093272185 | |
| OPPOSITION | - Inna Shehter-Harkavyk, "On the relationship between the adhesive properties and the structural features of fibrin sealants", Journal of Adhesion Science and Technology, (20120402), vol. 18, no. 12, doi:10.1163/1568561042323220, pages 1415 - 1425, XP093175043 | |
| OPPOSITION | - Ratnoff Oscar D., Potts Albert M., "THE ACCELERATING EFFECT OF CALCIUM AND OTHER CATIONS ON THE CONVERSION OF FIBRINOGEN TO FIBRIN 1", Journal of Clinical Investigation, American Society for Clinical Investigation, (19540201), vol. 33, no. 2, doi:10.1172/JCI102886, ISSN 0021-9738, pages 206 - 210, XP093308288 | |
| OPPOSITION | - Brass Eric P., Forman Walter B., Edwards Robert V., Lindan Olgierd, "Fibrin Formation: Effect of Calcium Ions", Blood, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (19781001), vol. 52, no. 4, doi:10.1182/blood.V52.4.654.654, ISSN 0006-4971, pages 654 - 658, XP093308301 | |
| OPPOSITION | - Mia-Jeanne van Rooy, "Platelet hyperactivity and fibrin clot structure in transient ischemic attack individuals in the presence of metabolic syndrome: a microscopy and thromboelastography study", Cardiovascular Diabetology, (2015), vol. 14, no. 1, doi:10.1186/s12933-015-0249-5, XP021227124 | |
| OPPOSITION | - Preininger B, Gerigk H, Bruckner J, Perka C, Schell H, Ellinghaus A, Schmidt-Bleek K, Duda G, "An experimental setup to evaluate innovative therapy options for the enhancement of bone healing using BMP as a benchmark - a pilot study", European Cells and Materials, vol. 23, doi:10.22203/eCM.v023a20, pages 262 - 272, XP093308278 | |
| OPPOSITION | - Cortelazzo Alessio, Guerranti Roberto, Bini Luca, Hope-Onyekwere Nnadozie, Muzzi Chiara, Leoncini Roberto, Pagani Roberto, "Effects of snake venom proteases on human fibrinogen chains", Blood Transfusion, S I M T I Servizi srl, Italy, Italy , (20100601), vol. 8, no. 3, doi:10.2450/2010.019S, ISSN 1723-2007, pages s120 - s125, XP093308295 | |
| OPPOSITION | - Lövgren Ann, "Recombinant snake venom prothrombin activators", Bioengineered, Landes Bioscience, US, US , (20130501), vol. 4, no. 3, doi:10.4161/bioe.22676, ISSN 2165-5979, pages 153 - 157, XP093308298 | |
| OTHER | - NOWAK GOETZ, "The ecarin clotting time, a universal method to quantify direct thrombin inhibitors", Pathophysiology of Haemost Thrombosis, CH , (20030101), vol. 33, no. 4, ISSN 1424-8832, pages 173 - 183, XP002451736 | - |
| OTHER | - Lovorka Grgurevic, "Recombinant Human Bone Morphogenetic Protein 6 Delivered Within Autologous Blood Coagulum Restores Critical Size Segmental Defects of Ulna in Rabbits", JBMR Plus, (20190501), vol. 3, no. 5, doi:10.1002/jbm4.10085, ISSN 2473-4039, XP093169906 | |
| OTHER | - Slobodan Vukicevic, "Autologous blood coagulum is a physiological carrier for BMP6 to induce new bone formation and promote posterolateral lumbar spine fusion in rabbits", JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, US , (20200101), vol. 14, no. 1, doi:10.1002/term.2981, ISSN 1932-6254, pages 147 - 159, XP093169900 | |
| OTHER | - Jelena Brkljacic, "Exogenous heparin binds and inhibits bone morphogenetic protein 6 biological activity", INTERNATIONAL ORTHOPEADICS, DE , (20130301), vol. 37, no. 3, doi:10.1007/s00264-012-1714-3, ISSN 0341-2695, pages 529 - 541, XP093169865 | |
| OTHER | - Slobodan Vukicevic, "The clinical use of bone morphogenetic proteins revisited: a novel biocompatible carrier device OSTEOGROW for bone healing", INTERNATIONAL ORTHOPEADICS, DE , (20140301), vol. 38, no. 3, doi:10.1007/s00264-013-2201-1, ISSN 0341-2695, pages 635 - 647, XP093169898 | |
| OTHER | - Stokovic Nikola; Ivanjko Natalia; Milesevic Marina; Matic Jelic Ivona; Bakic Kristian; Rumenovic Viktorija; Oppermann Hermann; Shimp Larry; Sampath T. Kuber; Pecina Marko; Vukicevic Slobodan, "Synthetic ceramic macroporous blocks as a scaffold in ectopic bone formation induced by recombinant human bone morphogenetic protein 6 within autologous blood coagulum in rats", INTERNATIONAL ORTHOPEADICS, DE , (20201014), vol. 45, no. 4, doi:10.1007/s00264-020-04847-9, ISSN 0341-2695, pages 1097 - 1107, XP037425800 | |
| OTHER | - Durdevic Dragan; Vlahovic Tomislav; Pehar Sanja; Miklic Dina; Oppermann Hermann; Bordukalo-Niksic Tatjana; Gavrankapetanovic Ismet; Jamakosmanovic Mehmed; Milosevic Milan; Martinovic Snjezana; Sampath T. Kuber; Peric Mihaela; Grgurevic Lovorka; Vukicevic Slobodan, "A novel autologous bone graft substitute comprised of rhBMP6 blood coagulum as carrier tested in a randomized and controlled Phase I trial in patients with distal radial fractures", Bone, GB , (20200727), vol. 140, doi:10.1016/j.bone.2020.115551, ISSN 8756-3282, XP086267598 | |
| OTHER | - Vaida Glatt, "Biomimetic Hematoma as a Novel Delivery Vehicle for rhBMP-2 to Potentiate the Healing of Nonunions and Bone Defects", JOURNAL OF ORTHOPAEDIC TRAUMA, US , (20231101), vol. 37, no. 11S, doi:10.1097/BOT.0000000000002692, ISSN 0890-5339, pages S33 - S39, XP093169883 | |
| OTHER | - Shehter-Harkavyk Inna, Bianco-Peled Havazelet, "On the relationship between the adhesive properties and the structural features of fibrin sealants", Journal of Adhesion Science and Technology, GB , (20040101), vol. 18, no. 12, doi:10.1163/1568561042323220, ISSN 0169-4243, pages 1415 - 1425, XP093175043 | |
| SEARCH | - MIA-JEANNE VAN ROOY ET AL, "Platelet hyperactivity and fibrin clot structure in transient ischemic attack individuals in the presence of metabolic syndrome: a microscopy and thromboelastography ? study", CARDIOVASC DIABETOLOGY, BIOMED CENTRAL, LONDON, GB, (20150704), vol. 14, no. 1, doi:10.1186/S12933-015-0249-5, ISSN 1475-2840, page 86, XP021227124 [X] 1-3,9-15 * page 3, column 2, paragraph 3 * * page 4, column 1, paragraph 2 - paragraph 3 * * page 5, column 1, paragraph 2 * * page 6, column 2, paragraph 1 * [A] 5 | |
