Methods For The Treatment Of Scleroderma - EP3860590

The patent EP3860590 was granted to Arena Pharmaceuticals on Jun 7, 2023. The application was originally filed on Oct 3, 2019 under application number EP19790404A. The patent is currently recorded with a legal status of "Revoked".

EP3860590

ARENA PHARMACEUTICALS
Application Number
EP19790404A
Filing Date
Oct 3, 2019
Status
Revoked
Jan 3, 2025
Grant Date
Jun 7, 2023
External Links
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Patent Summary

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Patent Oppositions (2)

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HAMM & WITTKOPPMar 7, 2024HAMM & WITTKOPPADMISSIBLE
TEVA PHARMACEUTICALSFeb 29, 2024ELKINGTON AND FIFEADMISSIBLE

Patent Citations (12) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONWO2009US04265-
DESCRIPTIONWO2011US00153-
DESCRIPTIONWO2016US38506-
DESCRIPTIONWO2010011316
DESCRIPTIONWO2011094008
DESCRIPTIONWO2016209809
INTERNATIONAL-SEARCH-REPORTEP1195165
INTERNATIONAL-SEARCH-REPORTWO2016209809
OPPOSITIONEP1195165
OPPOSITIONWO2010011316
OPPOSITIONWO2016112075
OPPOSITIONWO2016209809

Non-Patent Literature (NPL) Citations (24) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
EXAMINATION- CROSBY C M ET AL, "030 Etrasimod, an oral, selective sphingosine 1-phosphate receptor modulator improves skin inflammation in a contact hypersensitivity dermatitis model", JOURNAL OF INVESTIGATIVE DERMATOLOGY; ESDR 2019 ANNUAL MEETING - 49TH ANNUAL ESDR MEETING, ELSEVIER, NL; BORDEAUX, FRANCE, vol. 139, no. 9, Supplement, doi:10.1016/J.JID.2019.07.033, ISSN 0022-202X, (20190901), page S219, (20190904), XP009517577
OPPOSITION- Anonymous, "Handout on Health: Scleroderma", NIH Publication No. 16-4271, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), (20160801), pages 1 - 6, NIH Publication No. 16-4271, URL: https://web.archive.org/web/20170704182735/http://www.niams.nih.gov/Health_Info/Scleroderma/default.asp, XP093175132-
OPPOSITION- MONIQUE HINCHCLIFF, JOHN VARGA, "Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease", AMERICAN FAMILY PHYSICIAN, American Academy of Family Physicians, US, US , (20081015), vol. 78, no. 8, ISSN 0002-838X, pages 961 - 968, XP055346808-
OPPOSITION- Monique Hinchcliff , John Varga , "Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease", American Family Physician, US , (20081015), vol. 78, no. 8, ISSN 0002-838X, pages 961 - 968, XP093168407-
OPPOSITION- Huu Doanh Le, Matsushita Takashi, Jin Guihua, Hamaguchi Yasuhito, Hasegawa Minoru, Takehara Kazuhiko, Fujimoto Manabu, "FTY720 Ameliorates Murine Sclerodermatous Chronic Graft-Versus-Host Disease by Promoting Expansion of Splenic Regulatory Cells and Inhibiting Immune Cell Infiltration Into Skin : FTY720 Ameliorates Murine Sclerodermatous Chronic GVHD", Arthritis & Rheumatism, US , (20130601), vol. 65, no. 6, doi:10.1002/art.37933, ISSN 0004-3591, pages 1624 - 1635, XP055843797
OPPOSITION- Luzina Irina G, Atamas Sergei P, "41 Fibrotic Skin Diseases", Clinical and Basic Immunodermatology, Lodon, UK, Springer London, (20080930), pages 721 - 737, doi:10.1007/978-1-84800-165-7_41, ISBN 978-1-84800-164-0, XP093175119
OPPOSITION- Smith Gideon P, Chan Edwin S L, "Molecular Pathogenesis of Skin Fibrosis: Insight from Animal Models", CURRENT RHEUMATOLOGY REPORTS, CURRENT SCIENCE, PHILADELPHIA, PA, US, US , (20100201), vol. 12, no. 1, doi:10.1007/s11926-009-0080-7, ISSN 1523-3774, pages 26 - 33, XP093175105
OPPOSITION- Matthew B. Greenblatt; Antonios O. Aliprantis, "The Immune Pathogenesis of Scleroderma: Context Is Everything", Current Rheumatology Reports, Current Science Inc., New York, New York , (20130101), vol. 15, no. 1, doi:10.1007/s11926-012-0297-8, ISSN 1534-6307, pages 297 - 9, XP035166831
OPPOSITION- Scherlinger Marc, Guillotin Vivien, Truchetet Marie-Elise, Contin-Bordes Cécile, Sisirak Vanja, Duffau Pierre, Lazaro Estibaliz, Richez Christophe, Blanco Patrick, "Systemic lupus erythematosus and systemic sclerosis: All roads lead to platelets", AUTOIMMUNITY REVIEWS, NL , (20180601), vol. 17, no. 6, doi:10.1016/j.autrev.2018.01.012, ISSN 1568-9972, pages 625 - 635, XP093168430
OPPOSITION- Crosby C M; Komori H K; Adams J W, "030 Etrasimod, an oral, selective sphingosine 1-phosphate receptor modulator improves skin inflammation in a contact hypersensitivity dermatitis model", Journal of Investigative Dermatology, Elsevier, NL, NL , (20190901), vol. 139, no. 9, Supplement, doi:10.1016/j.jid.2019.07.033, ISSN 0022-202X, page S219, XP009517577
OPPOSITION- Crosby C M; Komori H K; Adams J W, "030 Etrasimod, an oral, selective sphingosine 1-phosphate receptor modulator improves skin inflammation in a contact hypersensitivity dermatitis model", Journal of Investigative Dermatology, NL , (20190901), vol. 139, no. 9 Supplement, doi:10.1016/j.jid.2019.07.033, ISSN 0022-202X, page S219, XP009517577
OPPOSITION- McGinley Marisa P; Cohen Jeffrey A, "Sphingosine 1-phosphate receptor modulators in multiple sclerosis and other conditions", The Lancet, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20210624), vol. 398, no. 10306, doi:10.1016/S0140-6736(21)00244-0, ISSN 0140-6736, pages 1184 - 1194, XP086791212
OPPOSITION- Daniel J. Buzard, Sun Hee Kim, Luis Lopez, Andrew Kawasaki, Xiuwen Zhu, Jeanne Moody, Lars Thoresen, Imelda Calderon, Brett Ullman, Sangdon Han, Juerg Lehmann, Tawfik Gharbaoui, Dipanjan Sengupta, Lorene Calvano, Antonio Garrido Montalban, You-An Ma, Carleton Sage, Yinghong Gao, Graeme Semple, Jeff Edwards, Jeremy Barden, Michael Morgan, Weichao Chen, Khawja Usmani, Chuan Chen, Abu Sadeque, Ronald J. Christopher, Jayant Thatte, Lixia Fu, Michelle Solomon, David Mills, Kevin Whelan, Hussien Al-Shamma, Joel Gatlin, Minh Le, Ibragim Gaidarov, Todd Anthony, David J. Unett, Anthony Blackburn, Jaimie Rueter, Scott Stirn, Dominic P. Behan, Robert M. Jones, "Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor", ACS MEDICINAL CHEMISTRY LETTERS, American Chemical Society, US, US , (20141211), vol. 5, no. 12, doi:10.1021/ml500389m, ISSN 1948-5875, pages 1313 - 1317, XP055477092
OPPOSITION- Daniel J. Buzard, Sun Hee Kim, Luis Lopez, Andrew Kawasaki, Xiuwen Zhu, Jeanne Moody, Lars Thoresen, Imelda Calderon, Brett Ullman, Sangdon Han, Juerg Lehmann, Tawfik Gharbaoui, Dipanjan Sengupta, Lorene Calvano, Antonio Garrido Montalban, You-An Ma, Carleton Sage, Yinghong Gao, Graeme Semple, Jeff Edwards, Jeremy Barden, Michael Morgan, Weichao Chen, Khawja Usmani, Chuan Chen, Abu Sadeque, Ronald J. Christopher, Jayant Thatte, Lixia Fu, Michelle Solomon, David Mills, Kevin Whelan, Hussien Al-Shamma, Joel Gatlin, Minh Le, Ibragim Gaidarov, Todd Anthony, David J. Unett, Anthony Blackburn, Jaimie Rueter, Scott Stirn, Dominic P. Behan, Robert M. Jones, "Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor", ACS MEDICINAL CHEMISTRY LETTERS, US , (20141211), vol. 5, no. 12, doi:10.1021/ml500389m, ISSN 1948-5875, pages 1313 - 1317, XP055477092
OPPOSITION- Christina G. Katsiari, Theodora Simopoulou, Ioannis Alexiou, Lazaros I. Sakkas, "Immunotherapy of systemic sclerosis", Human Vaccines & Immunotherapeutics, (20180101), vol. 14, no. 11, doi:10.1080/21645515.2018.1491508, pages 1 - 9, XP093168441
OPPOSITION- Li Ting, Liu Yaoyang, Xu Huji, "Successful treatment of infliximab in a patient with scleroderma : a case report", Medicine, US , (20170601), vol. 96, no. 22, doi:10.1097/MD.0000000000006737, ISSN 0025-7974, pages 1 - 3, XP093168436
OPPOSITION- Markus Thieme; Detlef Zillikens; Christian D. Sadik, "Sphingosine‐1‐phosphate modulators in inflammatory skin diseases - lining up for clinical translation", Experimental Dermatology, COPENHAGEN; DK , (20170202), vol. 26, no. 3, doi:10.1111/exd.13174, ISSN 0906-6705, pages 206 - 210, XP071778051
OPPOSITION- Varga John, Abraham David, "Systemic sclerosis: a prototypic multisystem fibrotic disorder", Journal of Clinical Investigation, American Society for Clinical Investigation, (20070301), vol. 117, no. 3, doi:10.1172/JCI31139, ISSN 0021-9738, pages 557 - 567, XP093175102
OPPOSITION- Miguel Guerrero, Mariangela Urbano, Edward Roberts, "Sphingosine 1-phosphate receptor 1 agonists: a patent review (2013-2015)", Expert Opinion on Therapeutic Patents, GB , (20160402), vol. 26, no. 4, doi:10.1517/13543776.2016.1157165, ISSN 1354-3776, pages 455 - 470, XP055376536
OPPOSITION- Postlethwaite, Pattanaik Debendra, Brown Monica, "Vascular involvement in systemic sclerosis (scleroderma)", Journal of Inflammation Research, GB , (20110101), doi:10.2147/JIR.S18145, ISSN 1178-7031, pages 105 - 125, XP093168447
OPPOSITION- Artlett Carol, "Animal models of systemic sclerosis: their utility and limitations", Open Access Rheumatology: Research and Reviews, Dove Medical Press, (20140701), vol. 6, doi:10.2147/OARRR.S50009, ISSN 1179-156X, pages 65 - 81, XP093175095
OPPOSITION- Debendra Pattanaik, Brown Monica, Postlethwaite Bradley C., Postlethwaite Arnold E., "Pathogenesis of systemic sclerosis", Frontiers in Immunology, (20150608), doi:10.3389/fimmu.2015.00272, pages 1 - 40, XP055287403
OPPOSITION- Soare Alina, Ramming Andreas, Avouac Jerome, Distler Jörg H.W., "Updates on animal models of systemic sclerosis", Journal of Scleroderma and Related Disorders, (20160101), vol. 1, no. 3, doi:10.5301/jsrd.5000220, ISSN 2397-1983, pages 266 - 276, XP093168453
OPPOSITION- Tokumura Akira, Carbone Laura D., Yoshioka Yasuko, Morishige Junichi, Kikuchi Masaki, Postlethwaite Arnold, Watsky Mitchell A, "Elevated Serum Levels of Arachidonoyl-lysophosphatidic Acid and Sphingosine 1-Phosphate in Systemic Sclerosis", International Journal of medical science, AU , (20090101), doi:10.7150/ijms.6.168, ISSN 1449-1907, pages 168 - 176, XP093168452

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