Process For The Purification Of Oligonucleotides - EP3870594

The patent EP3870594 was granted to F Hoffmann LA Roche on Aug 2, 2023. The application was originally filed on Oct 22, 2019 under application number EP19789691A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3870594

F HOFFMANN LA ROCHE
Application Number
EP19789691A
Filing Date
Oct 22, 2019
Status
Granted And Under Opposition
Jun 30, 2023
Grant Date
Aug 2, 2023
External Links
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CYTIVA SWEDENMay 2, 2024MAIWALDWITHDRAWN

Patent Citations (4) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
INTERNATIONAL-SEARCH-REPORTWO2008154639
INTERNATIONAL-SEARCH-REPORTWO2012010711
INTERNATIONAL-SEARCH-REPORTWO2015164773
OPPOSITIONWO2015061246

Non-Patent Literature (NPL) Citations (10) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- KROTZ et al., Organic Process Research & Development, (20030000), vol. 7, pages 47 - 52-
OPPOSITION- Anonymous, "Oligonucleotide synthesis", Wikipedia, Wikipedia, URL: https://en.wikipedia.org/w/index.php?title=Oligonucleotide synthesis&oldid=819533992, XP093189781-
OPPOSITION- Anonymous, "Oligonucleotide", Wikipedia, Wikipedia, URL: https://en.wikipedia.org/w/index.php?title=Oligonucleotide&oldid=795175353, XP093189790-
OPPOSITION- Anonymous, "Sartocube - Hydrosart Ultrafilter Cassette", Product Sheet Sartocube - Hydrosart Ultrafilter Cassette, Sartorius Stedim Biotech GmbH, (20120101), pages 1 - 2, Product Sheet Sartocube - Hydrosart Ultrafilter Cassette, URL: http://www.sartorius-sd.com.ua/files/Data_Sartocube_Hydrosart-Ultraf.pdf, XP093189628-
OPPOSITION- Schwartz L., Et Al, "Scientific & Technical Report Introduction to Tangential Flow Filtration for Laboratory and Process Development Applications", Pall Scientific & Technical Report, (20020101), pages 1 - 12, Pall Scientific & Technical Report, URL: https://www.pall.com/content/dam/pall/laboratory/literature-library/non-gated/Molecular_Tech_Report_Minimate_Intro_to_TFF.pdf, (20200527), XP055698772-
OPPOSITION- Scott Greg, "Avoiding Depurination During Trityl-on Purification", Application Note: TN-0008, Phenomenex, Inc., (20070101), pages 1 - 8, Application Note: TN-0008, URL: https://phenomenex.blob.core.windows.net/documents/26d078cf-e25b-49ef-9349-afbe0590de89.pdf, XP093189633-
OPPOSITION- E. Paredes, V. Aduda, K.L. Ackley, H. Cramer, "6.11 Manufacturing of Oligonucleotides", Comprehensive Medicinal Chemistry III, Vol 8: Case Histories in Recent Drug Discovery, ELSEVIER SCIENCE BV,, (20170615), vol. 6, pages 233 - 279, doi:10.1016/B978-0-12-409547-2.12423-0, ISBN 978-0-12-803200-8, XP009555921
OPPOSITION- Krotz Achim H., Mcelroy Bethany, Scozzari Anthony N., Cole Douglas L., Ravikumar Vasulinga T., "Controlled Detritylation of Antisense Oligonucleotides", Organic Process Research & Development, American Chemical Society, US, US , (20030101), vol. 7, no. 1, doi:10.1021/op020068u, ISSN 1083-6160, pages 47 - 52, XP093189598
OPPOSITION- Capaldi Daniel, Teasdale Andy, Henry Scott, Akhtar Nadim, Den Besten Cathaline, Gao-Sheridan Samantha, Kretschmer Matthias, Sharpe Neal, Andrews Ben, Burm Brigitte, Foy Jeffrey, "Impurities in Oligonucleotide Drug Substances and Drug Products", Nucleic Acid Therapeutics, Mary Ann Liebert, Inc. Publishers, US, US , (20171201), vol. 27, no. 6, doi:10.1089/nat.2017.0691, ISSN 2159-3337, pages 309 - 322, XP093189608
OPPOSITION- Egli Martin, Manoharan Muthiah, "Chemistry, structure and function of approved oligonucleotide therapeutics", Nucleic Acids Research, Oxford University Press, GB, GB , (20230411), vol. 51, no. 6, doi:10.1093/nar/gkad067, ISSN 0305-1048, pages 2529 - 2573, XP093189793

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