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The patent EP3897582 was granted to Novo Nordisk on Sep 11, 2024. The application was originally filed on Dec 20, 2019 under application number EP19828757A. The patent is currently recorded with a legal status of "Granted And Under Opposition".
A process for spray drying semaglutide, a GLP-1 peptide, that achieves improved yield by controlling the ratio of atomizing gas flow rate to feed flow rate. The process involves introducing the semaglutide solution into a spray dryer at a feed flow rate and introducing an atomizing gas at a flow rate that maintains a ratio of 1.0-1.7, independent of the apparatus used or outlet temperature. This optimized ratio enables reduced product loss and higher yield compared to conventional spray drying processes.

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