IP Verse

Methods For Harvesting Mammalian Cell Cultures - EP3926051

The patent EP3926051 was granted to Amgen on May 8, 2024. The application was originally filed on Jun 4, 2015 under application number EP21179944A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3926051

AMGEN
Application Number
EP21179944A
Filing Date
Jun 4, 2015
Status
Granted And Under Opposition
Apr 5, 2024
Grant Date
May 8, 2024
External Links
Slate, Register, Google Patents

Patent Summary

Patent Family

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateOpposition Status

Get instant alerts for new oppositions and patent status changes

ZWICKER SCHNAPPAUF & PARTNERFeb 7, 2025ADMISSIBLE

Patent Citations (44) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONAU588819B
DESCRIPTIONEP0367566
DESCRIPTIONEP0460846
DESCRIPTIONUS2013303732
DESCRIPTIONUS4695623
DESCRIPTIONUS4897471
DESCRIPTIONUS4968607
DESCRIPTIONUS5075222
DESCRIPTIONUS5149792
DESCRIPTIONUS5272064
DESCRIPTIONUS5395760
DESCRIPTIONUS5610279
DESCRIPTIONUS5721121
DESCRIPTIONUS5767064
DESCRIPTIONUS5856296
DESCRIPTIONUS5981713
DESCRIPTIONUS6015938
DESCRIPTIONUS6096728
DESCRIPTIONUS6204363
DESCRIPTIONUS6235883
DESCRIPTIONUS6271349
DESCRIPTIONUS6337072
DESCRIPTIONUS6544424
DESCRIPTIONUS7420183
DESCRIPTIONUS8053238
DESCRIPTIONWO0136637
DESCRIPTIONWO0192337
DESCRIPTIONWO2008154014
DESCRIPTIONWO2008157247
DESCRIPTIONWO2012115874
DESCRIPTIONWO2012145682
DESCRIPTIONWO2013006479
DESCRIPTIONWO2013040444
DESCRIPTIONWO2013063298
DESCRIPTIONWO2013138159
DESCRIPTIONWO2014022102
DESCRIPTIONWO9410308
DESCRIPTIONWO9428391
DESCRIPTIONWO9701633
OPPOSITIONUS2008206819
OPPOSITIONWO2008152075
SEARCHWO2008152075
SEARCHWO2009023562
SEARCHWO2010056584

Non-Patent Literature (NPL) Citations (40) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- BRADY et al., J Am Soc Mass Spectro, (20080000), vol. 19, pages 502 - 509-
DESCRIPTION- CAS, no. 90003-11-6-
DESCRIPTION- CHASIN et al., Som. Cell Molec. Genet., (19860000), vol. 12, pages 555 - 556-
DESCRIPTION- DOCHEN-KIANG, Cytokine Growth Factor Rev., (20020000), vol. 13, no. 1, pages 19 - 25-
DESCRIPTION- FUREY, Gen. Eng. News., (20020000), vol. 22, no. 7, pages 62 - 63-
DESCRIPTION- GRAHAM et al., J. Gen. Viral., (19770000), vol. 36, page 59-
DESCRIPTION- HAKANSSON et al., Structure, (19990000), vol. 7, pages 255 - 64-
DESCRIPTION- HARBURY et al., Nature, (19940000), vol. 371, pages 80 - 83-
DESCRIPTION- HARBURY et al., Science, (19930000), vol. 262, pages 1401 - 1293-
DESCRIPTION- Human Cytokines: Handbook for Basic and Clinical Research, Oxford University Press Inc., (19980000), vol. 1-3-
DESCRIPTION- KOLKEKAR et al., Biochemistry, (19970000), vol. 36, pages 10901 - 10909-
DESCRIPTION- LIU et al., Biotechnol. Prog., (20000000), vol. 16, pages 425 - 434-
DESCRIPTION- MAISONPIERRE et al., Science, (19970000), vol. 277, no. 5322, pages 55 - 60-
DESCRIPTION- MATHER, Annals NY Acad. Sci., (19820000), vol. 383, pages 44 - 68-
DESCRIPTION- MATHER, Biol. Reprod., (19800000), vol. 23, pages 243 - 251-
DESCRIPTION- "NCBI", Database accession no. NM_00682-
DESCRIPTION- RIIEGGPYTELA, Gene, (19950000), vol. 160, pages 257 - 62-
DESCRIPTION- STETTLER et al., Biotechnol Bioeng., (20061220), vol. 95, no. 6, pages 1228 - 33-
DESCRIPTION- The Cytokine Handbook, Academic Press, (20030000), vol. 1, 2-
DESCRIPTION- URLAUBCHASIN, Proc. Natl. Acad. Sci. USA, (19800000), vol. 77, page 4216-
DESCRIPTION- VOISARD et al., Biotechnology and Bioengineering, (20030000), vol. 82, pages 751 - 65-
OPPOSITION- David W. Murhammer, "Pluronic Polyols, Cell Protection", David W. Murhammer, Michael C. Flickinger, Stephen W. Drew, Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysis and Bioseparation, John Wiley & Sons, Inc., (19990101), pages 2019 - 2023, ISBN 0-471-16665-0, XP009561247-
OPPOSITION- Decision revoking European patent EP 3 152 317 B1, "Grandparent case"-
OPPOSITION- Dhinakar S Kompala, Sadettin S Ozturk, "Optimization of High Cell Density Perfusion Bioreacotors", Cell Culture Technology For Pharmaceutical And Cell -Based Therapies, (20051010), pages 387 - 416, XP055519914-
OPPOSITION- Main Request filed February 27, 2020-
OPPOSITION- Munir Cheryan, "Chapter 1: Introduction", Munir Cheryan, Munir Cheryan, Ultrafiltration and microfiltration handbook, 2nd edition, US, Taylor & Francis Group, (19980126), pages 1 - 30, ISBN 1-56676-598-6, XP009557430-
OPPOSITION- Seewoester Thomas, "Cell Separation and Product Capture", Cell Culture Technology for Pharmaceutical and Cell - Based Therapies. 1st ed., CRC Press, (20060101), pages 417 - 438, XP093003124-
OPPOSITION- Zhou, Et Al., "Mammalian cell bioreactors", Encyclopedia of Industrial Biotechnology: Bioprocess , Bioseparation , and Cell Technology, doi:10.1002/9780470054581.eib394, pages 1 - 10, Encyclopedia of Industrial Biotechnology: Bioprocess , Bioseparation , and Cell Technology, (20191206), XP055650285
OPPOSITION- Weiwei Hu et al., "The potential of hydrodynamic damage to animal cells of industrial relevance: current understanding", Cytotechnologx, (2011), vol. 63, doi:10.1007/s10616-011-9368-3, XP055545586
OPPOSITION- David Chang et al., "Investigation of interfacial properties of pure and mixed poloxamers for surfactant-mediated shear protection of mammalian cells", Colloids and Surfaces B: Biointerfaces, (2017), vol. 156, doi:10.1016/j.colsurfb.2017.05.040, XP085082047
OPPOSITION- Chisti, Y., "Animal-cell damage in sparged bioreactors", TRENDS IN BIOTECHNOLOGY., ELSEVIER PUBLICATIONS, CAMBRIDGE., GB, GB , (20001001), vol. 18, no. 10, doi:10.1016/S0167-7799(00)01474-8, ISSN 0167-7799, pages 420 - 432, XP004212028
SEARCH- CHRYSANTHOPOULOS P K ET AL, "Metabolomics for high-resolution monitoring of the cellular physiological state in cell culture engineering", METABOLIC ENGINEERING, ACADEMIC PRESS, US, vol. 12, no. 3, ISSN 1096-7176, (20100501), pages 212 - 222, (20091112), XP027013813 [A] 1-14-
SEARCH- ALTSHULER G L ET AL, "CONTINUOUS HYBRIDOMA GROWTH AND MONOCLONAL ANTIBODY PRODUCTION IN HOLLOW FIBER REACTORS-SEPARATORS", BIOTECHNOLOGY AND BIOENGINEERING, WILEY & SONS, HOBOKEN, NJ, US, (19860101), vol. 28, no. 5, doi:10.1002/BIT.260280503, ISSN 0006-3592, pages 646 - 658, XP002325535 [Y] 1-14 * Results section; page 13, line 7; figure 2; claims 1,3 * * page 18 *
SEARCH- S. ZHANG ET AL, "A comparison of oxygenation methods fro high-density perfusion culture of animal cells", BIOTECHNOLOGY AND BIOENGINEERING, Hoboken, USA, (19930325), vol. 41, no. 7, doi:10.1002/bit.260410702, ISSN 0006-3592, pages 685 - 692, XP055490027 [A] 1-14
SEARCH- YAO-MING HUANG ET AL, "Maximizing productivity of CHO cell-based fed-batch culture using chemically defined media conditions and typical manufacturing equipment", BIOTECHNOLOGY PROGRESS, (20100922), vol. 26, no. 5, doi:10.1002/btpr.436, ISSN 8756-7938, pages 1400 - 1410, XP055168194 [A] 1-14
SEARCH- WEIWEI HU ET AL, "The potential of hydrodynamic damage to animal cells of industrial relevance: current understanding", CYTOTECHNOLOGY, Dordrecht, (20110722), vol. 63, no. 5, doi:10.1007/s10616-011-9368-3, ISSN 0920-9069, pages 445 - 460, XP055545586 [A] 1-14 * page 451 - page 452; figure - *
SEARCH- RODRIGUEZ J ET AL, "High productivity of human recombinant beta-interferon from a low-temperature perfusion culture", JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 150, no. 4, doi:10.1016/J.JBIOTEC.2010.09.959, ISSN 0168-1656, (20101201), pages 509 - 518, (20101123), XP027516641 [A] 1-14
SEARCH- RAHUL GODAWAT ET AL, "End-to-end integrated fully continuous production of recombinant monoclonal antibodies", JOURNAL OF BIOTECHNOLOGY, (20150601), doi:10.1016/j.jbiotec.2015.06.393, ISSN 0168-1656, XP055205965 [AP] 1-14
SEARCH- GOUDAR C ET AL, "Metabolic flux analysis of CHO cells in perfusion culture by metabolite balancing and 2D [<13>C, <1>H] COSY NMR spectroscopy", METABOLIC ENGINEERING, ACADEMIC PRESS, US, vol. 12, no. 2, doi:10.1016/J.YMBEN.2009.10.007, ISSN 1096-7176, (20100301), pages 138 - 149, (20091105), XP026913663 [A] 1-14
SEARCH- SPYROS I. VERNARDIS ET AL, "Metabolic profiling reveals that time related physiological changes in mammalian cell perfusion cultures are bioreactor scale independent", METABOLIC ENGINEERING, (20130901), vol. 19, doi:10.1016/j.ymben.2013.04.005, ISSN 1096-7176, pages 1 - 9, XP055206004 [A] 1-14 * the whole document *

Download Citation Report

Get a free citation report including examiner, opposition, and international search citations.

Get Citation Report

Dossier Documents

The dossier documents provide a comprehensive record of the patent’s prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent’s legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents