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Detection Of Colorectal Cancer - EP3963111

The patent EP3963111 was granted to Universal Diagnostics on Jun 26, 2024. The application was originally filed on May 28, 2020 under application number EP20729993A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3963111

UNIVERSAL DIAGNOSTICS
Application Number
EP20729993A
Filing Date
May 28, 2020
Status
Granted And Under Opposition
Mar 15, 2024
Grant Date
Jun 26, 2024
External Links
Slate, Register, Google Patents

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JAMES POOLEJan 17, 2025CARPMAELS & RANSFORDADMISSIBLE

Patent Citations (7) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS10006925
INTERNATIONAL-SEARCH-REPORTEP2977467
INTERNATIONAL-SEARCH-REPORTWO2012167145
INTERNATIONAL-SEARCH-REPORTWO2015153283
OPPOSITIONEP2977467
OPPOSITIONWO2012167145
OPPOSITIONWO2015153283

Non-Patent Literature (NPL) Citations (18) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
OPPOSITION- Anonymous, "CpG Loci Identification", Illumina Inc., (20100101), URL: https://www.illumina.com/Documents/products/technotes/technote_cpg_loci_identification.pdf, (20200108), XP055655431-
OPPOSITION- Anonymous, "TruSeq® DNA Methylation Kit Reference Guide", Reference Guide, Illumina, (20160801), pages 1 - 40, Reference Guide, URL: https://www.researchgate.net/profile/J_Tarafdar/post/Are_there_a_simple_protocol_for_identification_of_DNA_methylation_profile_in_plants/attachment/5a17ca0ab53d2f6747c5954a/AS:564121651613697@1511508490718/download/truseq-dna-methylation-reference-guide-15066014-01.pdf, XP093255601-
OPPOSITION- Anonymous, "TruSeq DNA Methylation Library Preparation Guide", (20141201), pages 1 - 20, URL: http://support.illumina.com/content/dam/illumina-support/documents/documentation/chemistry_documentation/samplepreps_truseq/truseq-dna-methylation/truseq-dna-methylation-library-prep-guide-15066014-a.pdf, (20160627), XP055283756-
OPPOSITION- D10 - Genome browser views of ZNF132, ADAMTS2 (exons 1 and 2), LONRF2 (exon 1), ZNF542 (exons 1 and 2), and ZNF492 (exon 1)-
OPPOSITION- D15 - Evidence of publication date for Kruusmaa 2020-
OPPOSITION- D17 - HUMAN METHYLATION 450 MANIFEST FILE (EXTRACT)-
OPPOSITION- K Kruusmaa, Chersicola M, Bitenc M, Sanchez-Yague A, Schönthaler S, Pulverer W, Weinhaeusel A, "MSRE-qPCR for analysis of gene specific methylation can be accurately used for detection and validation of colorectal cancer-specific patterns", 4Bio Summit, Rotterdam 2018, (20180101), 4Bio Summit, Rotterdam 2018, URL: https://www.universaldx.com/wp-content/uploads/2017/05/4Bio-poster-November-2018.pdf, (20200819), XP055723835-
OPPOSITION- Antonio Fadda; Davide Gentilini; Loredana Moi; Ludovic Barault; Vera Piera Leoni; Pia Sulas; Luigi Zorcolo; Angelo Restivo; Francesco Cabras; Federica Fortunato; Cesare Zavattari; Liliana Varesco; Viviana Gismondi; Maria Rosaria De Miglio; Antonio Mario Scanu; Federica Colombi; Pasquale Lombardi; Ivana Sarotto; Eleonora Loi; Francesco Leone; Silvia Giordano; Federica Di Nicolantonio; Amedeo Columbano; Patrizia Zavattari, "Colorectal cancer early methylation alterations affect the crosstalk between cell and surrounding environment, tracing a biomarker signature specific for this tumor", International Journal of Cancer, John Wiley & Sons, Inc., US, US , (20180406), vol. 143, no. 4, doi:10.1002/ijc.31380, ISSN 0020-7136, pages 907 - 920, XP071290888
OPPOSITION- Fadda Antonio, Davide Gentilini; Loredana Moi; Ludovic Barault; Vera Piera Leoni; Pia Sulas; Luigi Zorcolo; Angelo Restivo; Francesco Cabras; Federica Fortunato; Cesare Zavattari; Liliana Varesco; Viviana Gismondi; Maria Rosaria De Miglio; Antonio Mario Scanu; Federica Colombi; Pasquale Lombardi; Ivana Sarotto; Eleonora Loi; Francesco Leone; Silvia Giordano; Federica Di Nicolantonio; Amedeo Columbano; Patrizia Zavattari, "Supporting Information: Supplementary Materials and methods; Tables S4, S7, and S8: Colorectal cancer early methylation alterations affect the crosstalk between cell and surrounding environment, tracing a biomarker signature specific for this tumor", International Journal of Cancer, John Wiley & Sons, Inc., US, US , (20180815), vol. 143, no. 4, doi:10.1002/ijc.31380, ISSN 0020-7136, pages 1 - 17, XP093256613
OPPOSITION- A. A. Melnikov, "MSRE-PCR for analysis of gene-specific DNA methylation", Nucleic Acids Research, Oxford University Press, GB, GB , (20050602), vol. 33, no. 10, doi:10.1093/nar/gni092, ISSN 0305-1048, pages e93 - e93, XP055278893
OPPOSITION- Wood Laura D., Parsons D. Williams, Jones Siân, Lin Jimmy, Sjöblom Tobias, Leary Rebecca J., Shen Dong, Boca Simina M., Barber Thomas, Ptak Janine, Silliman Natalie, Szabo Steve, Dezso Zoltan, Ustyanksky Vadim, Nikolskaya Tatiana, Nikolsky Yuri, Karchin Rachel, Wilson Paul A., Kaminker Joshua S., Zhang Zemin, Croshaw Randal, Willis Joseph, Dawson Dawn, Shipitsin Michail, Willson James K. V., Sukumar Saraswati, Polyak Kornelia, Park Ben Ho, Pethiyagoda Charit L., Pant P. V. Krishna, Ballinger Dennis G., Sparks Andrew B., Hartigan James, Smith Douglas R., Suh Erick, Papadopoulos Nickolas, Buckhaults Phillip, Markowitz Sanford D., Parmigiani Giovanni, Kinzler Kenneth W., Velculescu Victor E., Vogelstein Bert, "Supporting Online Material for: The Genomic Landscapes of Human Breast and Colorectal Cancers", Science, American Association for the Advancement of Science, US, US , (20171011), vol. 318, no. 5853, doi:10.1126/science.1145720, ISSN 0036-8075, pages 1108 - 1113, XP093255494
OPPOSITION- Kruusmaa Kristi, Bitenc Marko, Pulverer Walter, Weinhaeusel Andreas, Agudo José Luis Rodrigo, Delgado Andrés Barrientos, Yagüe Andrés Sánchez, Laiz José Manuel Rodríguez, Chersicola Marko, Knap Primož, Schönthaler Silvia, Ladabaum Uri, "Development and clinical performance of an accurate cell-free DNA (cfDNA) methylation assay for early detection of colorectal cancer", AACR Special Conference on Advances in Liquid Biopsies; January 13-16, 2020; Miami, FL, USA, (20200601), doi:10.1158/1557-3265.LiqBiop20-A05, pages 1 - 1, XP093256552
OPPOSITION- Felix Kordowski, Julia Kolarova, Clemens Schafmayer, Stephan Buch, Torsten Goldmann, Sebastian Marwitz, Christian Kugler, Swetlana Scheufele, Volker Gassling, Christopher G. Németh, Mario Brosch, Jochen Hampe, Ralph Lucius, Christian Röder, Holger Kalthoff, Reiner Siebert, Ole Ammerpohl, Karina Reiss, "Additional file: Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers", BMC Cancer, BIOMED CENTRAL, LONDON, GB, LONDON, GB , (20181201), vol. 18, no. 1, doi:10.1186/s12885-018-4701-2, ISSN 1471-2407, pages 796 - 2, XP055723762
OPPOSITION- Haidan Yan, Jun He, Qingzhou Guan, Hao Cai, Lin Zhang, Weicheng Zheng, Lishuang Qi, Suyun Zhang, Huaping Liu, Hongdong Li, Wenyuan Zhao, Sheng Yang, Zheng Guo, "Identifying CpG sites with different differential methylation frequencies in colorectal cancer tissues based on individualized differential methylation analysis", Oncotarget, (20170718), vol. 8, no. 29, doi:10.18632/oncotarget.17647, pages 47356 - 47364, XP055723769
OPPOSITION- D16a - Extract of Table S1 from D16 (Naumov 2013), XP055429289 & XP093256556
OPPOSITION- Naumov Vladimir A, Generozov Edward V, Zaharjevskaya Natalya B, Matushkina Darya S, Larin Andrey K, Chernyshov Stanislav V, Alekseev Mikhail V, Shelygin Yuri A, Govorun Vadim M, "Supplemental Material to: Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips", EPIGENETICS, Landes Bioscience, US, US , (20130901), vol. 8, no. 9, doi:10.4161/epi.25577, ISSN 1559-2294, pages 1 - 25, XP093256556
OPPOSITION- Vladimir A Naumov, Edward V Generozov, Natalya B Zaharjevskaya, Darya S Matushkina, Andrey K Larin, Stanislav V Chernyshov, Mikhail V Alekseev, Yuri A Shelygin, Vadim M Govorun, "Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips", EPIGENETICS, Landes Bioscience, US, US , (20130901), vol. 8, no. 9, doi:10.4161/epi.25577, ISSN 1559-2294, pages 921 - 934, XP055429289
OPPOSITION- Michail Galanopoulos, Nikolaos Tsoukalas, Ioannis S Papanikolaou, Maria Tolia, Maria Gazouli, Gerassimos J Mantzaris, "Abnormal DNA methylation as a cell-free circulating DNA biomarker for colorectal cancer detection: A review of literature", World Journal of Gastrointestinal Oncology, (20170101), vol. 9, no. 4, doi:10.4251/wjgo.v9.i4.142, ISSN 1948-5204, page 142, XP055723984

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