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Polymorphs Of (R)-N-(5-(5-Ethyl-1,2,4-Oxadiazol-3-Yl)-2,3-Dihydro-1H-Inden-1-Yl)-1-Methyl-1H-Pyrazole-4-Carboxamide - EP3999180

The patent EP3999180 was granted to Cytokinetics on May 8, 2024. The application was originally filed on Jul 16, 2020 under application number EP20753562A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3999180

CYTOKINETICS
Application Number
EP20753562A
Filing Date
Jul 16, 2020
Status
Granted And Under Opposition
Apr 5, 2024
Publication Date
May 8, 2024
External Links
Slate, Register, Google Patents

Patent Summary

Polymorphs of a therapeutic agent for treating cardiac diseases, particularly hypertrophic cardiomyopathy (HCM) and heart failure with preserved ejection fraction (HFpEF), that exhibit enhanced stability and therapeutic index compared to conventional forms. The polymorphs have distinct crystal structures that differ in physical properties, such as melting points, solubilities, and dissolution rates, which enable controlled manufacturing processes. These polymorphs retain the therapeutic activity of the parent compound while reducing adverse effects, making them a promising alternative for treating these conditions.

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Patent Family

Patent Oppositions

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GENERICS UKFeb 7, 2025RUSSELLADMISSIBLE

Patent Citations (2) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
INTERNATIONAL-SEARCH-REPORTWO2019144041
OPPOSITIONWO2019144041

Dossier Documents

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