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Composition Comprising Epa, Ma And Leucine For Improving Muscle Function - EP4051223

The patent EP4051223 was granted to Nutricia on Nov 27, 2024. The application was originally filed on Oct 30, 2020 under application number EP20801417A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP4051223

NUTRICIA
Application Number
EP20801417A
Filing Date
Oct 30, 2020
Status
Granted And Under Opposition
Oct 25, 2024
Publication Date
Nov 27, 2024
External Links
Slate, Register, Google Patents

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FRESENIUS KABI DEUTSCHLANDAug 13, 2025FRESENIUS KABI DEUTSCHLANDADMISSIBLE

Patent Citations (3) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
INTERNATIONAL-SEARCH-REPORTWO2006085144
INTERNATIONAL-SEARCH-REPORTWO2012141575
OPPOSITIONWO2008117062

Non-Patent Literature (NPL) Citations (25) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
DESCRIPTION- BROOKS MOBLEY et al., "whey protein-derived exosomes increase protein synthesis and hypertrophy in C2C12 myotubes", J. Dairy Sci., (20060000), vol. 100, pages 48 - 64
DESCRIPTION- JING et al., "alpha-lipoic acids promote the protein synthesis of C2C12 myotubes by the TLR2/PI13K signalling pathway", J. Agric. Food Chem., (20160000), vol. 64, pages 1720 - 1729
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DESCRIPTION- SALLES et al., "1,25(OH)2-vitamin D3 enhances the stimulating effect of leucine and insulin on protein synthesis rate through Akt/PKB and mTOR mediated pathways in murine C2C12 skeletal myotubes", Mol. Nutr. Food Res., (20130000), vol. 00, pages 1 - 10
DESCRIPTION- SONI et al., Nutrients, (20160000), vol. 8, page 543
INTERNATIONAL-SEARCH-REPORT- Novartis Medical Nutrition, "Resource (R) Support: specialized nutrition for people with cancer", Novartis Medical Nutrition, (20030101), pages 1 - 36, URL: https://www.nestle.com/investors/overview/mergers-and-acquisitions/boost, (20170216), XP055346865 [Y] 1-18 * tables 4, 5 * * page 16, paragraphs 1-5 * * page 14, paragraphs 1-7 * * figure 6 *
INTERNATIONAL-SEARCH-REPORT- NIKUL SONI ET AL, "Eicosapentaenoic and Docosahexaenoic Acid-Enriched High Fat Diet Delays Skeletal Muscle Degradation in Mice", NUTRIENTS, (20160903), vol. 8, no. 9, doi:10.3390/nu8090543, page 543, XP055705761 [YD] 1-18 * paragraph [02.3]; table 2 * * page 12, paragraph l - page 13, paragraph 1 * * page 13, paragraph 4 *
INTERNATIONAL-SEARCH-REPORT- YULAN LIU ET AL, "Fish Oil Enhances Intestinal Integrity and Inhibits TLR4 and NOD2 Signaling Pathways in Weaned Pigs after LPS Challenge", THE JOURNAL OF NUTRITION, US, (20120926), vol. 142, no. 11, doi:10.3945/jn.112.164947, ISSN 0022-3166, pages 2017 - 2024, XP055705758 [AD] 1-18 * table 1 *
OPPOSITION- Anonymous, "Nutritional Guidelines - For Complete and Complementary Pet Food for Cats and Dogs", Fédération européenne de l’industrie des aliments pour animaux familiers / The European Pet Food Industry Federation, (20140501), Fédération européenne de l’industrie des aliments pour animaux familiers / The European Pet Food Industry Federation, URL: https://www.fcav.unesp.br/Home/departamentos/clinicacv/AULUSCAVALIERICARCIOFI/fediaf_nutrtion_guideline2014.pdf, XP093307064
OPPOSITION- Anonymous, "Resource Support: specialized nutrition for people with cancer", Novartis, (20030101), XP093307062
OPPOSITION- Evans Essi, "More than corn needed to meet cows' amino acid requirements", AG Proud, (20160531), AG Proud, URL: https://www.agproud.com/articles/print/45578-more-than-corn-needed-to-meet-cows-amino-acid-requirements, XP093307060
OPPOSITION- Stibilj Vekoslava, Mojca Koman Rajsp, Antonija Holcman, "FATTY ACID COMPOSITION OF EGGS ENRICHED WITH OMEGA -3 FATTY ACIDS ON THE MARKET ", Zb. Biotehniske fak. Univ. v Ljubljani. Kmetijstvo. Zootehnika, (19990101), vol. 74, no. 2, pages 27 - 36, XP093307055
OPPOSITION- Y. Rolland et al., "Sarcopenia: Its assessment, etiology, pathogenesis, consequences and future perspectives", The Journal of Nutrition, Health & Aging, (2008), vol. 12, XP055913968
OPPOSITION- Kai Iwata et al., "Myristic acid specifically stabilizes diacylglycerol kinase δ protein in C2C12 skeletal muscle cells", Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, (20190411), vol. 1864, doi:10.1016/j.bbalip.2019.04.003, pages 1031 - 1038, XP085664225
OPPOSITION- Henry R., Peoples G. E., Mclennan P. L., "Muscle fatigue resistance in the rat hindlimb in vivo from low dietary intakes of tuna fish oil that selectively increase phospholipid n -3 docosahexaenoic acid according to muscle fibre type", British Journal of Nutrition, Cambridge University Press, UK, UK , (20150928), vol. 114, no. 6, doi:10.1017/S0007114515002512, ISSN 0007-1145, pages 873 - 884, XP093307048
OPPOSITION- Power Glen W, Newsholme Eric A, "Dietary Fatty Acids Influence the Activity and Metabolic Control of Mitochondrial Carnitine Palmitoyltransferase I in Rat Heart and Skeletal Muscle", J. Nutr., (19971101), vol. 127, doi:10.1093/jn/127.11.2142, pages 2142 - 2150, XP093307045
OPPOSITION- Reeves Philip G, "Components of the AIN-93 Diets as Improvements in the AIN-76A Diet ", The Journal of Nutrition, American Society for Nutrition, US, US , (19970501), vol. 127, no. 5, doi:10.1093/jn/127.5.838S, ISSN 0022-3166, pages 838S - 841S, XP093307058
OPPOSITION- Gingras Andrée‐anne, White Phillip James, Chouinard P. Yvan, Julien Pierre, Davis Teresa A., Dombrowski Luce, Couture Yvon, Dubreuil Pascal, Myre Alexandre, Bergeron Karen, Marette André, Thivierge M. Carole, "Long‐chain omega‐3 fatty acids regulate bovine whole‐body protein metabolism by promoting muscle insulin signalling to the Akt-mTOR-S6K1 pathway and insulin sensitivity", The Journal of Physiology, Wiley-Blackwell Publishing Ltd., GB, GB , (20070215), vol. 579, no. 1, doi:10.1113/jphysiol.2006.121079, ISSN 0022-3751, pages 269 - 284, XP093307046
OPPOSITION- Park Seok Won, Goodpaster Bret H., Lee Jung Sun, Kuller Lewis H., Boudreau Robert, De Rekeneire Nathalie, Harris Tamara B., Kritchevsky Stephen, Tylavsky Frances A., Nevitt Michael, Cho Yong-Wook, Newman Anne B., "Excessive Loss of Skeletal Muscle Mass in Older Adults With Type 2 Diabetes", DIABETES CARE, AMERICAN DIABETES ASSOCIATION, ALEXANDRIA, VA, US, US , (20091101), vol. 32, no. 11, doi:10.2337/dc09-0264, ISSN 0149-5992, pages 1993 - 1997, XP093307050
OPPOSITION- Caroline Wilkins et al., "Assessment of the influence of fatty acids on indices of insulin sensitivity and myocellular lipid content by use of magnetic resonance spectroscopy in cats", AJVR, (20040808), vol. 65, doi:10.2460/ajvr.2004.65.1090, XP093286777
OPPOSITION- Roger Fielding et al., "L-Carnitine Supplementation in Recovery after Exercise", Nutrients, (20180313), vol. 10, doi:10.3390/nu10030349, XP055706942
OPPOSITION- Réhault-Godbert Sophie, Guyot Nicolas, Nys Yves, "The Golden Egg: Nutritional Value, Bioactivities, and Emerging Benefits for Human Health", Nutrients, M D P I AG, CH, CH , vol. 11, no. 3, doi:10.3390/nu11030684, ISSN 2072-6643, page 684, XP093307059
OPPOSITION- Miranda Jose, Anton Xaquin, Redondo-Valbuena Celia, Roca-Saavedra Paula, Rodriguez Jose, Lamas Alexandre, Franco Carlos, Cepeda Alberto, "Egg and Egg-Derived Foods: Effects on Human Health and Use as Functional Foods", Nutrients, M D P I AG, CH, CH , vol. 7, no. 1, doi:10.3390/nu7010706, ISSN 2072-6643, pages 706 - 729, XP093307049
OPPOSITION- Rafiq et al., "Chemical Composition, Nitrogen Fractions and Amino Acids Profile of Milk from Different Animal Species", Asian Australas. J. Anim. Sci., (201607), vol. 29, doi:10.5713/ajas.15.0452, XP055515023

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