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Insulinotropic And Glucagonotropic Effects Of Beta-Lactoglobulin - EP4061399

The patent EP4061399 was granted to Arla Foods Amba on Feb 14, 2024. The application was originally filed on Nov 20, 2020 under application number EP20808127A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP4061399

ARLA FOODS AMBA
Application Number
EP20808127A
Filing Date
Nov 20, 2020
Status
Granted And Under Opposition
Jan 12, 2024
Grant Date
Feb 14, 2024
External Links
Slate, Register, Google Patents

Patent Summary

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Patent Family

Patent Oppositions (2)

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ZIMMERMANN & PARTNER PATENTANWALTE MBBNov 14, 2024ZIMMERMANN & PARTNER PATENTANWALTE MBBADMISSIBLE
NUTRICIANov 13, 2024NEDERLANDSCH OCTROOIBUREAUADMISSIBLE

Patent Citations (8) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONWO2017EP84553
DESCRIPTIONWO2019EP67015
DESCRIPTIONWO2018115520
DESCRIPTIONWO2020002426
INTERNATIONAL-SEARCH-REPORTUS2018153964
INTERNATIONAL-SEARCH-REPORTWO2010037736
OPPOSITIONUS2018153964
OPPOSITIONWO2020001765

Non-Patent Literature (NPL) Citations (26) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
EXAMINATION- JESPERSEN JAKOB G ET AL, Activated protein synthesis and suppressed protein breakdown signaling in skeletal muscle of critically ill patients., PLOS ONE 31 MAR 2011, VOL. 6, NR. 3, PAGE(S) E18090, (20110331), ISSN 1932-6203
EXAMINATION- MANN GAGANDEEP ET AL, Branched-chain Amino Acids: Catabolism in Skeletal Muscle and Implications for Muscle and Whole-body Metabolism., FRONTIERS IN PHYSIOLOGY 2021, VOL. 12, PAGE(S) 702826, (2021), ISSN 1664-042X
EXAMINATION- MOSE MAIKE ET AL, A model mimicking catabolic inflammatory disease; a controlled randomized study in humans., PLOS ONE 2020, VOL. 15, NR. 11, PAGE(S) E0241274, (2020), ISSN 1932-6203
EXAMINATION- MOSE M ET AL, Anabolic effects of oral leucine-rich protein with and without [beta]-hydroxybutyrate on muscle protein metabolism in a novel clinical model of systemic inflammation-a randomized crossover trial., THE AMERICAN JOURNAL OF CLINICAL NUTRITION 01 09 2021, VOL. 114, NR. 3, PAGE(S) 1159 - 1172, (20210901), ISSN 1938-3207
EXAMINATION- ZHAO YAN ET AL, Advances in the Role of Leucine-Sensing in the Regulation of Protein Synthesis in Aging Skeletal Muscle., FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2021, VOL. 9, PAGE(S) 646482, (2021), ISSN 2296-634X
EXAMINATION- STINE B. SMEDEGAARD ET AL, NUTRIENTS, (20210122), vol. 13, no. 2, doi:10.3390/nu13020308, page 308, XP055771676
OPPOSITION- Anonymous, "Cachexia", Wikipedia, (20240901), Wikipedia, URL: https://en.wikipedia.org/w/index.php?title=Cachexia&oldid=1243409099, XP093237963
OPPOSITION- Anonymous, "Muscle atrophy ", MedlinePlus, (20231231), MedlinePlus, URL: https://medlineplus.gov/ency/article/003188.htm, XP093237960
OPPOSITION- Boland M., Et Al, "chapter 3 Whey proteins", Handbook of food proteins, (20110101), pages 30 - 55, XP055549133
OPPOSITION- D15 - Summary of the dossier: Beta-Lactoglobulin, https://food.ec.europa.eu/safety/novel- food/authorisations/summaryapplications-and-notifications_en (published on 05.08.2020); no deciding/specific date to be found on the paper
OPPOSITION- D1 - Submissions of Patentee (25 April 2023)
OPPOSITION- D2 - Inventor Declaration
OPPOSITION- Rie Tsutsumi, "Peptides and Proteins in Whey and Their Benefits for Human Health", Austin Journal of Nutrition and Food Sciences, (2014), vol. 1, page 1, XP055678415
OPPOSITION- "Vanilla Flavor Whey Protein Dietary Supplement", GNPD, MINTEL, Database accession no. 6469573, XP055915996
OPPOSITION- M.P. Björkman, "Whey protein supplementation in nursing home residents. A randomized controlled trial.", European Geriatric Medicine, (2012), vol. 3, doi:10.1016/j.eurger.2012.03.010, XP028428838
OPPOSITION- Giovanni Tulipano, "Characterisation of the potential of β-lactoglobulin and α- lactalbumin as sources of bioactive peptides affecting incretin function: In silico and in vitro comparative studies", International Dairy Journal, (2015), vol. 48, doi:10.1016/j.idairyj.2015.01.008, XP029170275
OPPOSITION- Jakubowicz Daniela, Froy Oren, "Biochemical and metabolic mechanisms by which dietary whey protein may combat obesity and Type 2 diabetes", The Journal of Nutritional Biochemistry, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20130101), vol. 24, no. 1, doi:10.1016/j.jnutbio.2012.07.008, ISSN 0955-2863, pages 1 - 5, XP093237968
OPPOSITION- Isabelle Rieu, "Increased availability of leucine with leucine-rich whey proteins improves postprandial muscle protein synthesis in aging rats", Nutrition, (2007), vol. 23, doi:10.1016/j.nut.2006.12.013, XP022009607
OPPOSITION- Calbet, Et Al, "Plasma glucagon and insulin responses depend on the rate of appearance of amino acids after ingestion of different protein solutions in humans", J Nutr, (20020801), vol. 132, no. 8, doi:10.1093/jn/132.8.2174, pages 2174 - 2182, XP055716424
OPPOSITION- Yang Jichun, Chi Yujing, Burkhardt Brant R, Guan Youfei, Wolf Bryan A, "Leucine metabolism in regulation of insulin secretion from pancreatic beta cells", Nutrition reviews, (20100501), vol. 68, no. 5, doi:10.1111/j.1753-4887.2010.00282.x, ISSN 0029-6643, pages 270 - 279, XP093237958
OPPOSITION- Leenders Marika, Van Loon Luc Jc, "Leucine as a pharmaconutrient to prevent and treat sarcopenia and type 2 diabetes ", Nutrition reviews, (20111101), vol. 69, no. 11, doi:10.1111/j.1753-4887.2011.00443.x, ISSN 0029-6643, pages 675 - 689, XP093237957
OPPOSITION- Hollingworth Thomas William, Oke Siddhartha M, Patel Harnish, Smith Trevor R, "Getting to grips with sarcopenia: recent advances and practical management for the gastroenterologist", Frontline Gastroenterology, (20191230), vol. 12, no. 1, doi:10.1136/flgastro-2019-101348, ISSN 2041-4137, pages 53 - 61, XP093237964
OPPOSITION- Khan Usman Mir, Selamoglu Zeliha, "Nutritional and Medical Perspectives of Whey Protein: A Historical Overview", Journal of Pharmaceutical Care, (20191231), vol. 7, no. 4, doi:10.18502/jpc.v7i4.2380, ISSN 2322-4630, pages 112 - 117, XP093237965
OPPOSITION- Gilmartin Sarah, O’brien Nora, Giblin Linda, "Whey for Sarcopenia; Can Whey Peptides, Hydrolysates or Proteins Play a Beneficial Role?", Foods, MDPI AG, CH, CH , vol. 9, no. 6, doi:10.3390/foods9060750, ISSN 2304-8158, page 750, XP093237967
OPPOSITION- Stine B. Smedegaard, Maike Mose, Adam Hulman, Ulla R. Mikkelsen, Niels Møller, Gregers Wegener, Niels Jessen, Nikolaj Rittig, "β-Lactoglobulin Elevates Insulin and Glucagon Concentrations Compared with Whey Protein—A Randomized Double-Blinded Crossover Trial in Patients with Type Two Diabetes Mellitus", Nutrients, vol. 13, no. 2, doi:10.3390/nu13020308, page 308, XP055771676
OPPOSITION- Ralph J. Manders, "Insulinotropic and Muscle Protein Synthetic Effects of Branched- Chain Amino Acids: Potential Therapy for Type 2 Diabetes and Sarcopenia", Nutrients, (2012), vol. 4, doi:10.3390/nu4111664, XP055135189

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