| DESCRIPTION | - BOCZKOWSKI et al., Cancer Research, (20000000), vol. 60, pages 1028 - 1034 | - |
| DESCRIPTION | - BRUNELLE et al., Methods Enzymol, (20130000), vol. 530, pages 101 - 14 | - |
| DESCRIPTION | - ESTELLER, Nat. Rev. Genet., (20110000), vol. 15, no. 12, pages 861 - 74 | - |
| DESCRIPTION | - FOTIN-MLECZEK et al., J. Gene Med., (20120000), vol. 14, no. 6, pages 428 - 439 | - |
| DESCRIPTION | - GEALL et al., Semin. Immunol., (20130000), vol. 25, no. 2, pages 152 - 159 | - |
| DESCRIPTION | - KARIKO et al., Mol. Ther., (20120000), vol. 20, no. 5, pages 948 - 953 | - |
| DESCRIPTION | - KORMANN et al., Nat. Biotechnol., (20120000), vol. 29, no. 2, pages 154 - 157 | - |
| DESCRIPTION | - LUKE J et al., Vaccine, (20091030), vol. 27, no. 46, pages 6454 - 9 | - |
| DESCRIPTION | - MEYER, S.C. TEMME, Crit Rev Biochem Mol Biol, (20040000), vol. 39, no. 4, pages 197 - 216 | - |
| DESCRIPTION | - ROTHBREAKER, Annu Rev Biochem, (20090000), vol. 78, pages 305 - 334 | - |
| DESCRIPTION | - SETO et al., Molecular Cell, (20070000), vol. 26, no. 5, pages 603 - 609 | - |
| DESCRIPTION | - SIOMI et al., Nat. Rev. Mol. Cell. Biol., (20110000), vol. 12, pages 246 - 258 | - |
| EXAMINATION | - Charlotte Mignon ET AL, "Antibiotic-Free Selection in Biotherapeutics: Now and Forever", Pathogens, (20150403), vol. 4, no. 2, doi:10.3390/pathogens4020157, pages 157 - 181, XP055438148 | |
| OPPOSITION | - Addgene, "Plasmids 101: A Desktop Resource", Addgene, (20140901), pages 1 - 72, Addgene, URL: http://home.sandiego.edu/~josephprovost/addgeneplasmidbook.pdf, (20210907), XP055838376 | - |
| OPPOSITION | - Annonymous, "pBluescript II Phagemid Vectors", Instruction Manual, (20030101), pages 1 - 36, XP093229700 | - |
| OPPOSITION | - Annonymous, " pCMV-Script Vector", Instruction manual Revision A, (20080101), pages 1 - 13, XP093229826 | - |
| OPPOSITION | - Annonymous, "Plasmid Vectors ", Annonymous, Joseph Sambrook , E.F. Fritsch , T. Maniatis, Molecular cloning: a laboratory manual, Cold Spring Harbor Laboratory Press,U.S, (19890101), pages 1 - 110, ISBN 978-0879693091, XP093229660 | - |
| OPPOSITION | - Annonymous, "pSP64 cloning vector from Promega Biotec", Nucleotide , (19930726), Database accession no. L08943, URL: Genbank, XP093229659 | - |
| OPPOSITION | - Anonymous, "Addgene: pCRII-TOPO CMV-cGFP-bGH Poly(A) Sense", Addgene, (20120101), Addgene, URL: http://www.addgene.org/46835/, (20190626), XP055599908 | - |
| OPPOSITION | - Anonymous, "Addgene pUC19 Sequencing Result - Sequence Analyzer", addgene, (20241202), Database accession no. 222046, XP093229802 | - |
| OPPOSITION | - Anonymous, "Artificial sequence of plasmid pTrc99A", Nucleotide, (19940103), Database accession no. A13038.1, URL: ncbi, XP055838181 | - |
| OPPOSITION | - Anonymous, "CELLSCRIPT TM T7 mScript™ Standard mRNA Production System RNA for Translation in Cells", CELLSCRIPT, (20170101), XP093228177 | - |
| OPPOSITION | - Anonymous, "CHAPTER 1 Escherichia coli, Plasmids, and Bacteriophages", Anonymous, Frederick M Ausubel, Brent Roger, Kingston Robert E, Moore David D, Seidman J G, Smith John A, Current Protocols in Molecular Biology, John Wiley & Sons , (20030101), pages 1 - 99, ISBN 978-0-471-50338-5, XP093229365 | - |
| OPPOSITION | - Anonymous, "Cloning vector pEGFP-C1, complete sequence, enhanced green fluorescent protein (egfp) and neomycin phosphotransferase genes, complete cds", Nucleotide , (19960615), Database accession no. U55763, URL: Genbank, XP093229361 | - |
| OPPOSITION | - Anonymous, "Cloning vector pGEM-3Z", NUCLEOTIDE, (20040607), Database accession no. X65304, XP093228152 | - |
| OPPOSITION | - Anonymous, "D34: LEU2 3-isopropylmalate dehydrogenase [ Saccharomyces cerevisiae S288C ]", NCBI - Gene, (20240517), Database accession no. 850342, XP093228201 | - |
| OPPOSITION | - Anonymous, "Guidance for Industry - Guidance for Human Somatic Cell Therapy and Gene Therapy", U.S. Department of Health and Human Services; Food and Drug Administration; Center for Biologics Evaluation and Research, (19980301), U.S. Department of Health and Human Services; Food and Drug Administration; Center for Biologics Evaluation and Research, URL: Center for Biologics Evaluation and Research, XP093228132 | - |
| OPPOSITION | - Anonymous, "mMESSAGE mMACHINE® Kit High Yield Capped RNA Transcription Kit", Life - User Guide Catalog Numbers AM1340, AM1344, AM1348, (20121010), pages 1 - 36, Life - User Guide Catalog Numbers AM1340, AM1344, AM1348, (20240305), XP093137821 | - |
| OPPOSITION | - Anonymous, "mMESSAGE mMACHINE® T7 Ultra Kit - Synthesis of Translation Enhanced Capped Transcripts", User Guide, ambion®, (20140221), no. AM1345, pages 1 - 36, XP055897133 | - |
| OPPOSITION | - Anonymous, "pBluescript SK (-)", Addgene: Vector Database , (20241202), Database accession no. 1952, XP093229733 | - |
| OPPOSITION | - Anonymous, "pCMV6-Entry Vector (Myc-DDK Tagged)", Amsbio, (20091001), Amsbio , URL: http://www.amsbio.com/datasheets/pCMV6-Entry%20vector.pdf, XP002763069 | - |
| OPPOSITION | - Anonymous, "RNeasy® Mini Kit, Part 1 - Quick-StartProtocol", Qiagen, (20110101), Qiagen, URL: https://reedd.people.uic.edu/RNeasy-Mini-Kit-Part-1-EN.pdf, XP093228142 | - |
| OPPOSITION | - Anonymous, "RNeasy® Mini Kit, Part 2 - Quick-StartProtocol", Qiagen, (20110101), Qiagen, URL: https://www.google.com/search?q=RNeasy%C2%AE+Mini+Kit%2C+Part+2&sca_esv=f3453ca69a4fb869&sxsrf=ADLYWIKrz9sxFlrEthlz3M6PNSMa-QGlVg%3A1732627493446&source=hp&ei=JcxFZ7P4F66ii-gPpvyEmA8&iflsig=AL9hbdgAAAAAZ0XaNWn7qwoP7CX-6dba66LkzS84pL4V&ved=0ahUKEwjznpayjPqJAxUu0QIHHSY-AfMQ4dUDCBY&uact=5&oq=RNeasy%C2%AE+Mini+Kit%2C+Part+2&gs_lp=Egdnd3Mtd2l6IhlSTmVhc3nCriBNaW5pIEtpdCwgUGFydCAyMgYQABgWGB4yBhAAGBYYHjIGEAAYFhgeMgYQABgWGB4yBhAAGBYYHjIGEAAYFhgeMgYQABgWGB4yCBAAGIAEGKIESLsMUDVYNXABeACQAQCYAWygAWyqAQMwLjG4AQPIAQD4AQL4AQGYAgKgAn2oAgrCAgcQIxgnGOoCmAMK4gMFEgExIECSBwMxLjGgB6YG&sclient=gws-wiz, XP093228148 | - |
| OPPOSITION | - Anonymous, "Sequence Analyzer: pCRII-TOPO CMV-cGFP-bGH Poly(A) Sense", Addgene, (D055), pages 1 - 24 | - |
| OPPOSITION | - Anonymous, "Sequence Analyzer: pUC18", addgene, (20241202), Database accession no. 74675, XP093229770 | - |
| OPPOSITION | - Baibas Paulina , Xavier Soberon , Francisco Bolivar , Raymond L. Rodriguez, "The Plasmid, pBR322", Baibas Paulina , Xavier Soberon , Francisco Bolivar , Raymond L. Rodriguez, Raymond L Rodriquez , David T Denhardt, Vectors 1st edition, Butterworths , (19870101), pages 5 - 41, ISBN 978-0-409-90042-2, XP093229358 | - |
| OPPOSITION | - Broach James R, Yu-Yang Li , Ling-Chuan , Chen Wu , Makkuni Jayaram, "Vectors for High-Level, Inducible Expression of Cloned Genes in Yeast", Broach James R, Yu-Yang Li , Ling-Chuan , Chen Wu , Makkuni Jayaram, Masayori Inouye, Experimental Manipulation of Gene Expression, Academic Press , (19830101), pages 83 - 117, ISBN 978-0-12-372380-2, XP093229675 | - |
| OPPOSITION | - Brunelle Julie L , Green Rachel, "In vitro transcription from plasmid or PCR-amplified DNA.", Methods in enzymology, USA , (20130101), vol. 530, ISSN 1557-7988, pages 101 - 114, XP009190475 | - |
| OPPOSITION | - Conrad Susan E, Campbell Judith L, "Characterization of an improved in vitro DNA replication system for Escherichia coli plasmids", Nucleic Acids Research, (19790101), vol. 6, no. 10, pages 3289 - 3304, XP093229281 | - |
| OPPOSITION | - D100 - Plasmid Biopharmaceuticals Basics. Applications, and Manufacturing | - |
| OPPOSITION | - D111-Overview of claim requests and concordance with the previous ARs | - |
| OPPOSITION | - D114-O1 opposition filing against grandparent patent EP EP3334828, 28-JUL-2021 | - |
| OPPOSITION | - D115-O1 opposition filing against grandparent patent EP EP333482,01-MAR-2022 | - |
| OPPOSITION | - D116-O1 opposition filing against grandparent patent EP EP3334828 , 23-FEB-2024 | - |
| OPPOSITION | - D117-O1 opposition filing against grandparent patent EP EP3334828 , 09-APR-2024 | - |
| OPPOSITION | - D118-O1 opposition filing against grandparent patent EP EP3334828, 1-JUL-2024 | - |
| OPPOSITION | - D38 - Sequence alignment - ORI according to SEQ ID NO: 7 (“Sbjct”) vs. SEQ ID NO: 27 of D1 (“Query”) | - |
| OPPOSITION | - D39 - pDrive vector Sequence and Map, including kanamycin resistance gene sequence - SnapGene (page excerpt and sequence); accessed on 2024-06-13 | - |
| OPPOSITION | - D40 - Sequence alignment - KanaR gene of pDrive Vector (“Sbjct”) vs SEQ ID NO:27 of D1 (“Query”) | - |
| OPPOSITION | - D41 - Sequence Alignment - ORI according to SEQ ID NO: 7 (“Sbjct”) vs. SEQ ID NO: 9 of D4 (“Query”) | - |
| OPPOSITION | - D42 - Sequence Alignment - ORI according to SEQ ID NO: 7 (“Sbjct”) vs. Vector sequence of pGEM®-3Z of D12 (“Query”) | - |
| OPPOSITION | - D65- Experimental procedure leading to Certificates of Analysis for Lot Numbers 141197 and 14119 | - |
| OPPOSITION | - D85- Tightly regulated tac promoter vectors useful for the expression of unfused and fused proteins in Escherichia coli | - |
| OPPOSITION | - D89 - Overview of requests | - |
| OPPOSITION | - D90-Notification of the International Bureau on the recording of a change of the applicant for PCT/EP2015/068398 (the priority application | - |
| OPPOSITION | - D95-Summary of Article 123(2) EPC defects in claim requests of 21st December 2021 | - |
| OPPOSITION | - D98a-Comments for pVAX 1 2999 base pair | - |
| OPPOSITION | - Dubin Manu J; Bowler Chris; Benvenuto Giovanna, "A modified Gateway cloning strategy for overexpressing tagged proteins in plants", Plants methods, GB , (20080122), vol. 4, no. 1, ISSN 1746-4811, page 3, XP021039381 | - |
| OPPOSITION | - Egon Amann; Birgit Ochs; Karl-Josef Abel, "Tightly regulated tac promoter vectors useful for the expression of unfused and fused proteins in Escherichia coli", Gene, NL , (19880101), vol. 69, no. 2+index, ISSN 0378-1119, pages 301 - 315, XP001317098 | - |
| OPPOSITION | - G del Solar , R Giraldo, M J Ruiz-Echevarría, M Espinosa, R Díaz-Orejas, "Replication and control of circular bacterial plasmids", Microbiology and molecular biology reviews, US , (19980601), vol. 62, no. 2, doi:10.1128/MMBR.62.2.434-464.1998, ISSN 1092-2172, pages 434 - 464, XP002231301 | - |
| OPPOSITION | - J.M. Wells, P.W. Wilson, R.W.F. Le Page, "Improved cloning vectors and transformation procedure for Lactococcus lactis", Journal of Applied Microbiology, GB , (19930101), vol. 74, no. 6, doi:10.1111/j.1365-2672.1993.tb05195.x, ISSN 0021-8847, pages 629 - 636, XP008005890 | - |
| OPPOSITION | - Jorgensen Ellen D, Durbin Russell K, Risman Steven S, Mcallistero William T, Corp Lifecodes, Valhalla, "Specific Contacts between the Bacteriophage T3, T7 and SP6 RNA Prolymerases and Their Promoters", (19910101), pages 645 - 651, URL: https://www.jbc.org/article/S0021-9258(18)52483-2/pdf, (20230727), XP093067999 | - |
| OPPOSITION | - Jürgen Falbe, Hermann Römpp, Manfred Regitz, Martina Bach, "Polymere", Jürgen Falbe, Hermann Römpp, Manfred Regitz, Martina Bach, Jürgen Falbe, Hermann Römpp, Manfred Regitz, Martina Bach, Rompp-Lexikon Chemie 10th edition, Thieme, (19990101), pages 3470 - 3471, ISBN 978-3-13-735010-1, XP093229876 | - |
| OPPOSITION | - Link J Andrew , Philipps Dereth , Church M George, "Methods for Generating Precise Deletions and insertions in the Genome of Wild-Type Escherichia coli; Application to Open Reading Frame Characterization", Journal of Bacteriology, US , (19971001), vol. 179., no. 20., ISSN 0021-9193, pages 6228 - 6237, XP000890089 | - |
| OPPOSITION | - Livermorea David M, Trevor G. Winstanley , Kevin P. Shannon, "Interpretative reading: recognizing the unusual and inferring resistance mechanisms from resistance phenotypes", Journal of Antimicrobial Chemotherapy, (20010101), vol. 48, no. Suppl S1, pages 87 - 102, XP093229762 | - |
| OPPOSITION | - Masaru Ikegami, Uchida Satoshi, Uchida Hirokuni, Nagata Kazuya, Kataoka Kazunori, Itaka Keiji, Nemunaitis John, Senzer Neil, Kuhn Joseph, Shanahan David, Roth Alyssa, Kumar Padmasini, Luo Xiuquan, Brunicardi F C, Jay Chris M, Rao Donald D, Crowley Samuel T, Li Jing, Rice Kevin G, "114. Enhanced Transfection of mRNA Transcribed From Elongated-poly(A/T) Tail- Containing Vector", Molecular Therapy, (20140501), vol. 22, no. Supp 1, pages S43 - S43, XP055561764 | - |
| OPPOSITION | - Masayori Inouye, Broach James R., "Vectors for High-Level, Inducible Expression of Cloned Genes in Yeast", Masayori Inouye, Broach James R., James R. Broach , Yu-Yang , Li Ling-Chuan , Chen Wu , Makkuni Jayaram, Experimental Manipulation of Gene Expression 1st Ed., Academic Press , (19830101), pages 83 - 117, ISBN 0-12 372380-9, XP055838041 | - |
| OPPOSITION | - Promega, "pGEM ® -3Z Vector", Promega Technical Bulletin, (20090501), Promega Technical Bulletin, URL: https://nld.promega.com/products/cloning-and-dna-markers/cloning-vectors-and-kits/pgem_3z-vector/?catNum=P2151, (20210906), XP055838070 | - |
| OPPOSITION | - R Lahijani , G Hulley, G Soriano, N A Horn, M Marquet, "High-yield production of pBR322-derived plasmids intended for human gene therapy by employing a temperature-controllable point mutation", Human gene therapy, GB , (19961020), vol. 07., no. 7, doi:10.1089/hum.1996.7.16-1971, ISSN 1043-0342, pages 1971 - 1980., XP002120738 | - |
| OPPOSITION | - Sequence listing (for WO 2013040557A2) | - |
| OPPOSITION | - SUTCLIFFE J. G., "COMPLETE NUCLEOTIDE SEQUENCE OF THE ESCHERICHIA COLI PLASMID PBR322", COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, NEW YORK, NY, US, US , (19790101), vol. 43., pages 77 - 90., XP002915924 | - |
| OPPOSITION | - Yang Ying, Sha Ma, "A Beginner's Guide to Bioprocess Modes -Batch, Fed-Batch, and Continuous Fermentation", Eppendorf Application Note 408, (20200101), pages 1 - 16, XP093229709 | - |
| OPPOSITION | - ZIBERT A ET AL, "INFECTIOUS FOOT-AND-MOUTH DISEASE VIRUS DERIVED FROM A CLONED FULL-LENGTH COMPLEMENTARY DNA", Journal of Virology, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, US , (19900101), vol. 64, no. 6, ISSN 0022-538X, pages 2467 - 2473, XP002763070 | - |
| OPPOSITION | - Chartrain Michel, "Chapter 2 The productionof plasmid DNA vaccine in Escherichia colk A novel bacterial-based vaccine production platform", Chartrain Michel, Emily Wen , Ronald Ellis , Narahari S Pujar, Vaccine Development and Manufacturing, John Wiley & Sons, Inc, (20150101), pages 25 - 49, doi:10.1002/9781118870914, ISBN 978-0-470-26194-1, XP093229788 | |
| OPPOSITION | - Eby A. Bassiri, "pGLO mutagenesis: A laboratory procedure in molecular biology for biology students", Biochemistry and Molecular Biology Education, US , (20111111), vol. 39, no. 6, doi:10.1002/bmb.20538, ISSN 1470-8175, pages 432 - 439, XP072247638 | |
| OPPOSITION | - Aaron E. Carnes, Jeremy M. Luke, Justin M. Vincent, Sheryl Anderson, Angela Schukar, Clague P. Hodgson, James A. Williams, "Critical design criteria for minimal antibiotic-free plasmid vectors necessary to combine robust RNA Pol II and Pol III-mediated eukaryotic expression with high bacterial production yields", The Journal of Gene Medicine, (20101030), vol. 12, no. 10, doi:10.1002/jgm.1499, ISSN 1099-498X, pages 818 - 831, XP055079559 | |
| OPPOSITION | - Andrew G. Bert, Joanna Burrows, Cameron S. Osborne, Peter N. Cockerill, "Generation of an Improved Luciferase Reporter Gene Plasmid That Employs a Novel Mechanism for High-Copy Replication", Plasmid, US , (20000901), vol. 44, no. 2, doi:10.1006/plas.2000.1474, ISSN 0147-619X, pages 173 - 182, XP055223651 | |
| OPPOSITION | - Villadsen John , Jens Nielsen,Gunnar Liden , "Chapter 9 Design of Fermentation Processes", Villadsen John , Jens Nielsen,Gunnar Liden , Villadsen John , Jens Nielsen,Gunnar Liden, Bioreaction engineering principles Third edition, Springer , (20110101), pages 383 - 458, doi:10.1007/978-l-4419-9688-6_9, XP093229778 | |
| OPPOSITION | - Oka, A. , Sugisaki, H. , Takanami, M, "Nucleotide sequence of the kanamycin resistance transposon Tn903", Journal of Molecular Biology, United Kingdom , (19810405), vol. 147, no. 2, doi:10.1016/0022-2836(81)90438-1, ISSN 0022-2836, pages 217 - 226, XP024020782 | |
| OPPOSITION | - Tomizawa, J.-I., "Control of ColE1 plasmid replication: Binding of RNA I to RNA II and inhibition of primer formation", Cell, Amsterdam NL , (19861010), vol. 47, no. 1, doi:10.1016/0092-8674(86)90369-7, ISSN 0092-8674, pages 89 - 97, XP023883036 | |
| OPPOSITION | - Hoffman, L.M. ; Donaldson, D.D., "Vectors for in vitro synthesis of poly(A)+RNA transcripts", Gene, NL , (19880715), vol. 67, no. 1, doi:10.1016/0378-1119(88)90017-0, ISSN 0378-1119, pages 137 - 140, XP023544191 | |
| OPPOSITION | - Geall Andrew J.; Mandl Christian W.; Ulmer Jeffrey B., "RNA: The new revolution in nucleic acid vaccines", Seminars in immunology, US , (19000101), vol. 25, no. 2, doi:10.1016/j.smim.2013.05.001, ISSN 1044-5323, pages 152 - 159, XP028694558 | |
| OPPOSITION | - Jeremy Luke, Aaron E. Carnes, Clague P. Hodgson, and James A. Williams, "Improved antibiotic-free DNA vaccine vectors utilizing a novel RNA based plasmid selection system", PubMed Central (PMC) Author Manuscript - VACCINE, (20091030), vol. 27, no. 46, Sp. Iss. SI, doi:10.1016/j.vaccine.2009.06.017, pages 1 - 16, XP002629888 | |
| OPPOSITION | - Ismail et al., "Scaling-up recombinant plasmid DNA for clinical trial: Current concern, solution and status", Vaccine, (2012), vol. 30, doi:10.1016/j.vaccine.2012.02.061, XP093014880 | |
| OPPOSITION | - Grabherr Reingard , Bayer Karl, "Impact of targeted vector design on ColE1 plasmid replication", Trends in Biotechnology, GB , (20020601), vol. 20, no. 6, doi:10.1016/S0167-7799(02)01950-9, ISSN 0167-7799, pages 257 - 260, XP002561699 | |
| OPPOSITION | - Preiss Thomas, Muckenthaler Martina, Hentze Matthias W., "Poly(A)-tail-promoted translation in yeast: Implications for translational control", RNA, US , (19981101), vol. 4, no. 11, doi:10.1017/S1355838298980669, ISSN 1355-8382, pages 1321 - 1331, XP055838129 | |
| OPPOSITION | - Berg Douglas E, "Julian Davies and the discovery of kanamycin resistance transposon Tn5", The Journal of Antibiotics, UK / JP, (20161012), vol. 70, no. 4, doi:10.1038/ja.2016.120, ISSN 0021-8820, pages 339 - 346, XP037651239 | |
| OPPOSITION | - Alexandra E Grier , Stephen Burleigh , Jaya Sahni , Courtnee A Clough , Victoire Cardot , Dongwook C Choe , Michelle C Krutein , David J Rawlings , Michael C Jensen , Andrew M Scharenberg , Kyle Jacoby, "pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences.", Molecular therapy - Nucleic acids, (20160419), vol. 5, doi:10.1038/mtna.2016.21, pages 1 - 10, XP002787530 | |
| OPPOSITION | - YENOFSKY ET AL., "A mutant neomycin phosphotransferase II gene reduces the resistance of transformants to antibiotic selection pressure", Proceedings of the National Academy of Sciences (PNAS), National Academy of Sciences, (19900101), vol. 87, doi:10.1073/pnas.87.9.3435, ISSN 0027-8424, pages 3435 - 3439, XP002142155 | |
| OPPOSITION | - Akbar Z. et al. Shyadehi, "The Mechanism of the Acyl-Carbon Bond Cleavage Reaction Catalyzed by Recombinant Sterol 14α-Demethylase of Candida albicans (Other Names Are: Lanosterol 14α-Demethylase, P-45014DM, and CYP51)", Journal of Biological Chemistry, (1996), vol. 271, doi:10.1074/jbc.271.21.12445, XP055838033 | |
| OPPOSITION | - Krasilnikova M. M., "Transcription through a simple DNA repeat blocks replication elongation", The EMBO journal / European Molecular Biology Organization, Oxford , (19980901), vol. 17, no. 17, doi:10.1093/emboj/17.17.5095, ISSN 0261-4189, pages 5095 - 5102, XP055838030 | |
| OPPOSITION | - Enrique Viguera , Danielle Canceill , S Dusko Ehrlich, "Replication slippage involves DNA polymerase pausing and dissociation", The EMBO journal / European Molecular Biology Organization, Oxford , (20010515), vol. 20, no. 10, doi:10.1093/emboj/20.10.2587, ISSN 0261-4189, pages 2587 - 2595, XP093166766 | |
| OPPOSITION | - R. Kiyama, M. Oishi, "In Vitro Transcription of a Poly(dA){middle dot}Poly(dT)-Containing Sequence is Inhibited by Interaction between the Template and Its Transcripts", Nucleic Acids Research, GB , (19961101), vol. 24, no. 22, doi:10.1093/nar/24.22.4577, ISSN 0305-1048, pages 4577 - 4583, XP055732821 | |
| OPPOSITION | - T T Yang , L Cheng, S R Kain, "Optimized codon usage and chromophore mutations provide enhanced sensitivity with the green fluorescent protein", Nucleic Acids Research, GB , (19960101), vol. 24., no. 22., doi:10.1093/nar/24.22.4592, ISSN 0305-1048, pages 4592 - 4593, XP002120084 | |
| OPPOSITION | - J. E. Wilusz, C. K. Jnbaptiste, L. Y. Lu, C.-D. Kuhn, L. Joshua-Tor, P. A. Sharp, "A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tails", Genes & Development, (20121101), vol. 26, no. 21, doi:10.1101/gad.204438.112, ISSN 08909369, pages 2392 - 2407, XP055194808 | |
| OPPOSITION | - Franklin Kristyn, Clarke Anthony J., "Overexpression and Characterization of the Chromosomal Aminoglycoside 2′- N -Acetyltransferase of Providencia stuartii", Antimicrobial agents and chemotherapy, US , (20010801), vol. 45, no. 8, doi:10.1128/AAC.45.8.2238-2244.2001, ISSN 0066-4804, pages 2238 - 2244, XP093123302 | |
| OPPOSITION | - Kangas T T, Cooney C L, Gomez R F, "Expression of a proline-enriched protein in Escherichia coli", Applied and environmental microbiology, US , (19820301), vol. 43, no. 3, doi:10.1128/aem.43.3.629-635.1982, ISSN 0099-2240, pages 629 - 635, XP055838055 | |
| OPPOSITION | - Parsons R, Anderson M E, Tegtmeyer P, "Three domains in the simian virus 40 core origin orchestrate the binding, melting, and DNA helicase activities of T antigen", Journal of Virology, US , (19900201), vol. 64, no. 2, doi:10.1128/jvi.64.2.509-518.1990, ISSN 0022-538X, pages 509 - 518, XP055838053 | |
| OPPOSITION | - Mirkin Ekaterina V., Mirkin Sergei M., "Mechanisms of Transcription-Replication Collisions in Bacteria", Molecular and cellular biology, US , (20050201), vol. 25, no. 3, doi:10.1128/MCB.25.3.888-895.2005, ISSN 0270-7306, pages 888 - 895, XP055838146 | |
| OPPOSITION | - HOLTKAMP SILKE ET AL, "Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells.", Blood, issue 832, American Society of Hematology, US, US , (20061215), vol. 108, no. 13, doi:10.1182/blood-2006-04-015024, ISSN 0006-4971, pages 4009 - 4017, XP002418545 | |
| OPPOSITION | - Trepotec Zeljka; Geiger Johannes; Plank Christian; Aneja Manish K; Rudolph Carsten, "Segmented poly(A) tails significantly reduce recombination of plasmid DNA without affecting mRNA translation efficiency or half-life", RNA, US , (20190331), vol. 25, no. 4, doi:10.1261/rna.069286.118, ISSN 1355-8382, pages 507 - 518, XP009517039 | |
| OPPOSITION | - Montgomery Donna L., Kristala Jones Prather, "Design of Plasmid DNA Constructs for Vaccines", Montgomery Donna L., Kristala Jones Prather, W. M. Saltzman, H. Shen, J. L. Brandsma, DNA Vaccines, Humana Press, (20060822), pages 11 - 22, doi:10.1385/1-59745-168-1:11, ISBN 978-1-59745-168-0, XP093229744 | |
| OPPOSITION | - Garner G. Moulton, "Recombinant fed-batch fermentation using Escherichia coli", Garner G. Moulton, Garner G. Moulton, Fed-batch fermentation A practical guide to scalable recombinant protein production in Escherichia coli, Woodhead Publishing, (20140101), pages 63 - 76, doi:10.1533/9781908818331.63, ISBN 978-1-907568-92-3, XP093229728 | |
| OPPOSITION | - W Van Der Velden, Voorma Harry O, Thomas Adri A M, "Vector Design for Optimal Protein Expression", Biotechniques, (20010901), vol. 31, no. 3, doi:10.2144/01313rr02, pages 1 - 8, XP055668162 | |
| OPPOSITION | - Wright G D, Thompson P R, "Aminoglycoside phosphotransferases proteins structure and mechanism", Frontiers in bioscience, US , (19990101), vol. 4, no. 4, doi:10.2741/wright, ISSN 1093-9946, pages 9 - 21, XP093123299 | |
| OPPOSITION | - German L. Rosano, Eduardo A. Ceccarelli, "Recombinant protein expression in Escherichia coli: advances and challenges", Frontiers in Microbiology, (20140417), vol. 5, doi:10.3389/fmicb.2014.00172, pages 1 - 17, XP055474138 | |
| OPPOSITION | - Charlotte Mignon, Régis Sodoyer, Bettina Werle, "Antibiotic-Free Selection in Biotherapeutics: Now and Forever", Pathogens, vol. 4, no. 2, doi:10.3390/pathogens4020157, pages 157 - 181, XP055438148 | |
| SEARCH | - Addgene, "Addgene: pCRII-TOPO CMV-cGFP-bGH Poly(A) Sense", (20120101), URL: http://www.addgene.org/46835/, (20190626), XP055599908 [I] 1-25 * the whole document * | - |
| SEARCH | - Addgene, "Addgene pCRII-TOPO CMV-cGFP-bGH Poly(A) Sense - Sequence Analyzer", (20120101), URL: https://www.addgene.org/browse/sequence/66680/, (20190626), XP055599859 [I] 1-25 * the whole document * | - |
| SEARCH | - Agilent Revision C, "pCMV-Script Vector Instruction Manual Catalog #212220 For Research Use Only. Not for use in diagnostic procedures", (20150101), URL: https://www.agilent.com/cs/library/usermanuals/public/212220.pdf, (20230118), XP093015113 [I] 1-25 * the whole document * | - |
| SEARCH | - DUBIN MANU J ET AL, "A modified Gateway cloning strategy for overexpressing tagged proteins in plants", PLANT METHODS, BIOMED CENTRAL, LONDON, GB, (20080122), vol. 4, no. 1, ISSN 1746-4811, page 3, XP021039381 [A] 1-25 * the whole document, in particular Fig. 2 * | - |
| SEARCH | - LAHIJANI R ET AL, "High-yield production of pBR322-derived plasmids intended for human gene therapy by employing a temperature-controllable point mutation", HUMAN GENE THERAPY, MARY ANN LIEBERT, NEW YORK ,NY, US, (19961020), vol. 7, no. 7, ISSN 1043-0342, pages 1971 - 1980, XP002120738 [A] 1-25 | - |
| SEARCH | - Novopro, "pCMV-Script vector map and sequence", (19970101), URL: https://www.novoprolabs.com/vector/V11243, (20230118), XP093015106 [I] 1-25 * the whole document * | - |
| SEARCH | - "pCMV6-Entry Vector (Myc-DDK Tagged)", (200910), Amsbio, URL: http://www.amsbio.com/datasheets/pCMV6-Entry%20vector.pdf, XP002763069 [A] 1-25 * the whole document * | - |
| SEARCH | - SOLAR DEL G ET AL, "Replication and control of circular bacterial plasmids", MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, AMERICAN SOCIETY FOR MICROBIOLOGY, US, (19980601), vol. 62, no. 2, ISSN 1092-2172, pages 434 - 464, XP002231301 [A] 1-25 | - |
| SEARCH | - Susan E Conrad ET AL, "volume 6 Number 101979 Nucleic Acids Research Characterization of an improved in vitro DNA replication system for Escherichia coli plasmids", (19790101), URL: http://nar.oxfordjournals.org/content/6/10/3289.full.pdf, (20151026), XP055223462 [A] 1-25 | - |
| SEARCH | - WELLS J M ET AL, "IMPROVED CLONING VECTORS AND TRANSFORMATION PROCEDURE FOR LACTOCOCCUS LACTIS", JOURNAL OF APPLIED BACTERIOLOGY, BLACKWELL PUBLISHING LTD., OXFORD, GB, (19930101), vol. 74, no. 6, ISSN 0021-8847, pages 629 - 636, XP008005890 [A] 1-25 | - |
| SEARCH | - ZIBERT A ET AL, "INFECTIOUS FOOT-AND-MOUTH DISEASE VIRUS DERIVED FROM A CLONED FULL-LENGTH COMPLEMENTARY DNA", JOURNAL OF VIROLOGY, (1990), vol. 64, no. 6, ISSN 0022-538X, pages 2467 - 2473, XP002763070 [A] 1-25 * the whole document * | - |
| SEARCH | - ANDREW G. BERT ET AL, "Generation of an Improved Luciferase Reporter Gene Plasmid That Employs a Novel Mechanism for High-Copy Replication", PLASMID, US, (20000901), vol. 44, no. 2, doi:10.1006/plas.2000.1474, ISSN 0147-619X, pages 173 - 182, XP055223651 [A] 1-25 | |
| SEARCH | - TOMIZAWA ET AL, "Control of ColE1 plasmid replication: Binding of RNA I to RNA II and inhibition of primer formation", CELL, CELL PRESS, US, vol. 47, no. 1, doi:10.1016/0092-8674(86)90369-7, ISSN 0092-8674, (19861010), pages 89 - 97, (19861010), XP023883036 [A] 1-25 | |
| SEARCH | - HOFFMAN L M ET AL, "Vectors for in vitro synthesis of poly(A)^+RNA transcripts", GENE, ELSEVIER AMSTERDAM, NL, vol. 67, no. 1, doi:10.1016/0378-1119(88)90017-0, ISSN 0378-1119, (19880715), pages 137 - 140, (19880715), XP025705755 [A] 1-25 | |
| SEARCH | - ISMAIL RUZILA ET AL, "Scaling-up recombinant plasmid DNA for clinical trial: Current concern, solution and status", VACCINE, AMSTERDAM, NL, (20120901), vol. 30, no. 41, doi:10.1016/j.vaccine.2012.02.061, ISSN 0264-410X, pages 5914 - 5920, XP093014880 [A] 1-25 | |
| SEARCH | - GRABHERR R ET AL, "Impact of targeted vector design on ColE1 plasmid replication", TRENDS IN BIOTECHNOLOGY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, (20020601), vol. 20, no. 6, doi:10.1016/S0167-7799(02)01950-9, ISSN 0167-7799, pages 257 - 260, XP004352764 [A] 1-25 | |
