Protein Purification

Patent No. EP1543038 (titled "Protein Purification") was filed by Genentech on Sep 8, 2003. The application was issued on Aug 5, 2020.

Purifying antibodies like huMAb4D5-8 from mixtures containing the antibody and contaminants using ion exchange chromatography. The method involves loading the composition onto an ion exchange resin, washing with a buffer whose conductivity increases, and eluting the antibody with a higher conductivity buffer. This allows selective elution of the antibody by changing the ionic strength. The washing gradient helps remove impurities without eluting the antibody.

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Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

Company	Opposition Date	Representative
BAYER	Feb 28, 2018	VIERING

Dossier Documents

The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.

Date
Description

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Jul 9, 2020
Decision to maintain the European patent in amended form
Jul 9, 2020
Decision to maintain the European patent in amended form
Jul 6, 2020
Termination of the opposition proceedings with maintenance of patent
Jun 25, 2020
(Electronic) Receipt
Jun 25, 2020
Description
Jun 25, 2020
Filing of the translation of the amended claims
Jun 25, 2020
Letter accompanying subsequently filed items
Jun 23, 2020
(Electronic) Receipt
Jun 23, 2020
Filing of the translation of the amended claims
Jun 23, 2020
French translation of claims
Jun 23, 2020
German translation of the claims
Jun 23, 2020
Letter accompanying subsequently filed items
Jun 19, 2020
Communication of amended entries
May 25, 2020
Request concerning representative opponent
Mar 19, 2020
Document concerning representation
Mar 16, 2020
Communication of bibliographic data
Mar 16, 2020
Communication to opponent concerning maintenance
Mar 16, 2020
Communication with request to file translations
Mar 11, 2020
Refund of fees
Mar 10, 2020
F3324 Closure of the appeal proceedings: withdrawal of the appeal/ application/ opposition
Mar 10, 2020
F3324 Closure of the appeal proceedings: withdrawal of the appeal/ application/ opposition
Mar 10, 2020
Maintenance of the patent with the documents specified in the final decision
Mar 5, 2020
F3345 Forwarding of submissions to parties
Mar 2, 2020
Composition of the board (T)
Feb 28, 2020
(Electronic) Receipt
Feb 28, 2020
Letter accompanying subsequently filed items
Feb 28, 2020
Withdrawal of an appeal
Jan 17, 2020
F3204 Communication of the file number to the parties
Jan 17, 2020
F3204 Communication of the file number to the parties
Jan 2, 2020
(Electronic) Receipt
Jan 2, 2020
Letter accompanying subsequently filed items
Jan 2, 2020
Notice of appeal
Nov 4, 2019
Advice of delivery
Oct 31, 2019
Advice of delivery
Oct 29, 2019
(Electronic) Receipt
Oct 29, 2019
Advice of delivery
Oct 29, 2019
Letter accompanying subsequently filed items
Oct 28, 2019
Advice of delivery
Oct 24, 2019
Acknowledgement of a document
Oct 24, 2019
Acknowledgement of a document
Oct 24, 2019
Annex to the communication - opposition
Oct 24, 2019
Decision of the Opposition Division and instruction
Oct 24, 2019
Grounds for the decision (Annex) - opposition
Oct 24, 2019
Interlocutory decision in opposition proceedings
Oct 24, 2019
Internal form - Opposition/addressees
Oct 24, 2019
Internal form - Opposition/addressees
Oct 24, 2019
Means of redress
Oct 24, 2019
Minutes of the oral proceedings (Opposition Division) - conclusion of the proceedings
Oct 24, 2019
Minutes of the oral proceedings (Opposition Division) - conclusion of the proceedings
Oct 24, 2019
Minutes of the oral proceedings (Opposition Division) - introduction of the parties
Oct 24, 2019
OPPODREX with handwritten amendments
Oct 24, 2019
Provision of a copy of the minutes - opposition procedure
Oct 24, 2019
Scanned annex to a communication - opposition procedure
May 3, 2019
Information about the result of oral proceedings
Mar 5, 2019
Brief communication - Opposition proceedings
Mar 5, 2019
Brief communication - Opposition proceedings
Mar 4, 2019
Communication of amended entries
Mar 4, 2019
Communication of amended entries
Feb 28, 2019
(Electronic) Receipt
Feb 28, 2019
Amended claims with annotations
Feb 28, 2019
Claims
Feb 28, 2019
Letter accompanying subsequently filed items
Feb 28, 2019
Request for interpreters during oral proceedings
Feb 27, 2019
(Electronic) Receipt
Feb 27, 2019
Authorisation
Feb 27, 2019
Letter accompanying subsequently filed items
Feb 27, 2019
Request for interpreters during oral proceedings
Dec 20, 2018
Communication of amended entries concerning the representative
Dec 14, 2018
Submission concerning change of applicant's representative
Dec 13, 2018
Submission concerning change of applicant's representative
Nov 26, 2018
Advice of delivery
Nov 22, 2018
Advice of delivery
Nov 21, 2018
Advice of delivery
Nov 20, 2018
(Electronic) Receipt
Nov 20, 2018
Advice of delivery
Nov 20, 2018
Letter accompanying subsequently filed items
Nov 13, 2018
Acknowledgement of a document
Nov 13, 2018
Acknowledgement of a document
Nov 13, 2018
Annex to the communication - opposition
Nov 13, 2018
Brief communication - Opposition proceedings
Nov 13, 2018
Communication of amended entries
Nov 13, 2018
Communication of amended entries
Nov 13, 2018
Information concerning oral proceedings
Nov 13, 2018
Summons to attend oral proceedings
Nov 13, 2018
Summons to attend oral proceedings
Nov 5, 2018
Request for change of opponent's representative
Sep 5, 2018
Communication of amended entries concerning the representative
Aug 29, 2018
(Electronic) Receipt
Aug 29, 2018
Letter accompanying subsequently filed items
Aug 29, 2018
Submission concerning change of applicant's representative
Jul 31, 2018
Brief communication - Opposition proceedings
Jul 24, 2018
(Electronic) Receipt
Jul 24, 2018
Amended claims with annotations
Jul 24, 2018
Amended claims with annotations
Jul 24, 2018
Amended claims with annotations
Jul 24, 2018
Amended claims with annotations
Jul 24, 2018
Amended claims with annotations
Jul 24, 2018
Amended claims with annotations
Jul 24, 2018
Amended claims with annotations
Jul 24, 2018
Amended claims with annotations
Jul 24, 2018
Amended claims with annotations
Jul 24, 2018
Amended claims with annotations
Jul 24, 2018
Amended claims with annotations
Jul 24, 2018
Amended claims with annotations
Jul 24, 2018
Claims
Jul 24, 2018
Claims
Jul 24, 2018
Claims
Jul 24, 2018
Claims
Jul 24, 2018
Claims
Jul 24, 2018
Claims
Jul 24, 2018
Claims
Jul 24, 2018
Claims
Jul 24, 2018
Claims
Jul 24, 2018
Claims
Jul 24, 2018
Claims
Jul 24, 2018
Claims
Jul 24, 2018
Letter accompanying subsequently filed items
Jul 24, 2018
Reply of the patent proprietor to the notice(s) of opposition
Mar 14, 2018
Communication of a notice of opposition and request to file observations
Mar 14, 2018
Notice of further oppositions to opponent(s)
Mar 13, 2018
Brief communication - Opposition proceedings
Mar 9, 2018
Communication of a notice of opposition - first information to patent proprietor
Mar 8, 2018
(Electronic) Receipt
Mar 8, 2018
Letter accompanying subsequently filed items
Mar 6, 2018
Request for documents
Feb 28, 2018
(Electronic) Receipt
Feb 28, 2018
Notice of opposition
Feb 28, 2018
Notice of opposition
May 31, 2017
Transmission of the certificate for a European patent pursuant to Rule 74 EPC
May 8, 2017
Decision to grant a European patent
Apr 21, 2017
Notice on debiting of fees
Apr 6, 2017
(Electronic) Receipt
Apr 6, 2017
Filing of the translations of the claims
Apr 6, 2017
French translation of claims
Apr 6, 2017
German translation of the claims
Apr 6, 2017
Letter accompanying subsequently filed items
Nov 30, 2016
Bibliographic data of the European patent application
Nov 30, 2016
Communication about intention to grant a European patent
Nov 30, 2016
Intention to grant (signatures)
Nov 30, 2016
Text intended for grant (clean copy)
Nov 30, 2016
Text intended for grant (sequence listing)
Nov 30, 2016
Text intended for grant (version for approval)
Jun 23, 2016
(Electronic) Receipt
Jun 23, 2016
Claims
Jun 23, 2016
Description
Jun 23, 2016
Letter accompanying subsequently filed items
Jun 23, 2016
Reply to communication from the Examining Division
Apr 28, 2016
Grant of extension of time limit (examination procedure)
Apr 21, 2016
(Electronic) Receipt
Apr 21, 2016
Letter accompanying subsequently filed items
Apr 21, 2016
Request for extension of time limit to communication from the Examining Division
Dec 18, 2015
Annex to the communication
Dec 18, 2015
Communication from the Examining Division
Dec 9, 2015
Processing of request for correction of text proposed for grant or third party observations (from 01-04-2012)
Nov 27, 2015
(Electronic) Receipt
Nov 27, 2015
Claims
Nov 27, 2015
Description
Nov 27, 2015
Letter accompanying subsequently filed items
Nov 27, 2015
Request for correction/amendment of the text proposed for grant sent from 01.04.2012
Jul 24, 2015
Bibliographic data of the European patent application
Jul 24, 2015
Communication about intention to grant a European patent
Jul 24, 2015
Intention to grant (signatures)
Jul 24, 2015
Text intended for grant (clean copy)
Jul 24, 2015
Text intended for grant (sequence listing)
Jul 24, 2015
Text intended for grant (version for approval)
May 11, 2015
Submission concerning representation
May 8, 2015
Submission concerning representation
Mar 4, 2015
Decision to allow further processing
Feb 20, 2015
(Electronic) Receipt
Feb 20, 2015
Claims
Feb 20, 2015
Letter accompanying subsequently filed items
Feb 20, 2015
Request for further processing
Dec 11, 2014
Application deemed to be withdrawn (no reply to communication from the Examining Division)
Sep 17, 2014
Grant of extension of time limit (examination procedure)
Sep 11, 2014
(Electronic) Receipt
Sep 11, 2014
Letter accompanying subsequently filed items
Sep 11, 2014
Request for extension of time limit to communication from the Examining Division
May 6, 2014
Annex to the communication
May 6, 2014
Communication from the Examining Division
Jul 19, 2011
(Electronic) Receipt
Jul 19, 2011
Amended claims with annotations
Jul 19, 2011
Claims
Jul 19, 2011
Letter accompanying subsequently filed items
Jul 19, 2011
Reply to communication from the Examining Division
May 27, 2011
Grant of extension of time limit (examination procedure)
May 23, 2011
(Electronic) Receipt
May 23, 2011
Letter accompanying subsequently filed items
May 23, 2011
Request for extension of time limit to communication from the Examining Division
Jan 21, 2011
Annex to the communication
Jan 21, 2011
Communication from the Examining Division
Apr 22, 2010
Claims
Apr 22, 2010
Reply to communication from the Examining Division
Dec 16, 2009
Annex to a communication
Dec 16, 2009
Annex to the communication
Dec 16, 2009
Communication from the Examining Division
Apr 21, 2009
Annex
Apr 21, 2009
Annex
Apr 21, 2009
Claims
Apr 21, 2009
Claims
Apr 21, 2009
Description
Apr 21, 2009
Drawings
Apr 21, 2009
Reply to communication from the Examining Division
Apr 17, 2009
Claims
Apr 17, 2009
Claims
Apr 17, 2009
Description
Apr 17, 2009
Drawings
Apr 17, 2009
Non-patent literature cited during the examination procedure
Apr 17, 2009
Reply to communication from the Examining Division
Feb 23, 2009
Request for extension of time limit to communication from the Examining Division
Feb 18, 2009
Request for extension of time limit to communication from the Examining Division
Nov 28, 2008
Submission concerning representation
Oct 10, 2008
Annex to the communication
Oct 10, 2008
Communication from the Examining Division
Aug 13, 2008
CDS Clean up - amended applicant details
Mar 7, 2008
Maintenance of the application
Jan 8, 2008
Invitation to declare maintenance of the application and to correct deficiencies in the Written Opinion/amend application
Dec 21, 2007
Communication regarding the transmission of the European search report
Dec 21, 2007
Supplementary European search report
May 11, 2005
Notification on forthcoming publication of bibliographic data
Apr 22, 2005
Communication regarding possible amendment of claims/payment of claims fees
Mar 16, 2005
Non-scannable object
Mar 16, 2005
Request for entry into the European phase
Mar 16, 2005
Sequence listing
Feb 7, 2005
Copy of the international preliminary examination report
Jan 28, 2005
Information on entry into European phase
Oct 20, 2004
Reminder for payment period (examination fee/designation fees)
Oct 14, 2004
Copy of the international search report
Oct 14, 2004
International publication of the international search report
Jul 16, 2004
Notification of the recording of a change
Jun 9, 2004
Priority document (electronically transmitted)
Mar 25, 2004
Published international application - A2

EP1543038

GENENTECH

Application Number: EP03795664A
Filing Date: Sep 8, 2003
Status: Patent Maintained As Amended; Jul 3, 2020
Publication Date: Aug 5, 2020
External Links: Slate, Register , Google Patents

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Protein Purification

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Dossier Documents

EP1543038