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Selective Immunodepletion Of Endogenous Stem Cell Niche For Engraftment

Patent No. EP2088864 (titled "Selective Immunodepletion Of Endogenous Stem Cell Niche For Engraftment") was filed by The Board OF Trustees OF The Leland Stanford Junior University on Nov 2, 2007. The application was issued on Aug 27, 2025.

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Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

Company	Opposition Date	Representative
BOSCH JEHLE PATENTANWALTSGESELLSCHAFT	May 16, 2018	HOFFMANN EITLE

Dossier Documents

The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.

Date
Description

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Jul 31, 2025
Decision to maintain the European patent in amended form
Jul 31, 2025
Decision to maintain the European patent in amended form
Jul 11, 2025
(Electronic) Receipt
Jul 11, 2025
Filing of the translation of the amended claims
Jul 11, 2025
French translation of claims
Jul 11, 2025
German translation of the claims
Jul 11, 2025
Letter accompanying subsequently filed items
May 21, 2025
Communication of bibliographic data
May 21, 2025
Communication to opponent concerning maintenance
May 21, 2025
Communication with request to file translations
May 15, 2025
Maintenance of the patent with the documents specified in the final decision
Jan 28, 2025
Brief communication - Opposition proceedings
Jan 28, 2025
Brief communication - Opposition proceedings
Jan 28, 2025
Decision of the Opposition Division and instruction
Jan 28, 2025
Druckexemplar in opposition procedure
Jan 28, 2025
Grounds for the decision (Annex) - opposition
Jan 28, 2025
Interlocutory decision in opposition proceedings
Jan 28, 2025
Interlocutory decision in opposition proceedings
Jan 28, 2025
Means of redress
Sep 12, 2024
Brief communication - Opposition proceedings
Sep 12, 2024
Brief communication - Opposition proceedings
Sep 12, 2024
Communication inviting the parties to file observations
Sep 12, 2024
Communication inviting the parties to file observations
Sep 12, 2024
Scanned annex to a communication - opposition procedure
May 3, 2024
Brief communication - Opposition proceedings
Apr 29, 2024
(Electronic) Receipt
Apr 29, 2024
Auxiliary request during Opposition procedure
Apr 29, 2024
Auxiliary request during Opposition procedure - 11
Apr 29, 2024
Letter accompanying subsequently filed items
Apr 29, 2024
Reply to an examination report in opposition proceedings
Apr 15, 2024
Brief communication - Opposition proceedings
Apr 15, 2024
Brief communication - Opposition proceedings
Apr 15, 2024
Communication inviting the parties to file observations
Apr 15, 2024
Communication inviting the parties to file observations
Apr 15, 2024
Scanned annex to a communication - opposition procedure
Sep 15, 2023
Brief communication - Opposition proceedings
Sep 11, 2023
(Electronic) Receipt
Sep 11, 2023
Amended description with annotations
Sep 11, 2023
Description
Sep 11, 2023
Letter accompanying subsequently filed items
Sep 11, 2023
Reply to an examination report in opposition proceedings
Jun 30, 2023
Annex to the communication - opposition
Jun 30, 2023
Brief communication - Opposition proceedings
Jun 30, 2023
Brief communication - Opposition proceedings
Jun 30, 2023
Communication inviting the parties to file observations
Jun 30, 2023
Communication inviting the parties to file observations
Jun 6, 2023
Decision of the Board of Appeal
Jun 6, 2023
F3032 Notification(s) of the decision
May 26, 2023
F3004 Communication of the Registry
Feb 17, 2023
F3013 Oral Proceedings: Forwarding minutes
Feb 17, 2023
F3316 Oral Proceedings: Minutes (Appellant: Opponent)
Feb 3, 2023
(Electronic) Receipt
Feb 3, 2023
F3345 Forwarding of submissions to parties
Feb 3, 2023
Letter accompanying subsequently filed items
Feb 3, 2023
Letter dealing with oral proceedings during the appeal procedure
Jan 25, 2023
(Electronic) Receipt
Jan 25, 2023
F3305 Communication of the Board of Appeal (ex parte/ inter partes)
Jan 25, 2023
F3345 Forwarding of submissions to parties
Jan 25, 2023
Letter accompanying subsequently filed items
Jan 25, 2023
Letter dealing with oral proceedings during the appeal procedure
Jan 20, 2023
(Electronic) Receipt
Jan 20, 2023
F3345 Forwarding of submissions to parties
Jan 20, 2023
Letter accompanying subsequently filed items
Jan 20, 2023
Letter dealing with oral proceedings during the appeal procedure
Jan 17, 2023
F3345 Forwarding of submissions to parties
Jan 17, 2023
F3345 Forwarding of submissions to parties
Jan 16, 2023
(Electronic) Receipt
Jan 16, 2023
(Electronic) Receipt
Jan 16, 2023
Cited document during appeal procedure
Jan 16, 2023
Letter accompanying subsequently filed items
Jan 16, 2023
Letter accompanying subsequently filed items
Jan 16, 2023
Letter dealing with oral proceedings during the appeal procedure
Jan 16, 2023
Request for interpreters during oral proceedings
Oct 21, 2022
F3305 Communication of the Board of Appeal (ex parte/ inter partes)
May 27, 2022
F3011.1 Oral Proceedings: summons
May 27, 2022
F3350 Communication regarding oral proceedings (art. 15 Rules of Procedure of the Boards of Appeal)
May 23, 2022
F3010 Oral proceedings: order for summons
May 20, 2022
F3303.16 Change of composition of the Board (T)
Jan 28, 2022
F3303.16 Change of composition of the Board (T)
Dec 23, 2021
F3345 Forwarding of submissions to parties
Dec 20, 2021
(Electronic) Receipt
Dec 20, 2021
Cited document during appeal procedure
Dec 20, 2021
Letter accompanying subsequently filed items
Dec 20, 2021
Letter relating to Appeal Procedure
Aug 13, 2021
Communication of amended entries concerning the representative
Aug 5, 2021
Letter accompanying subsequently filed items
Aug 5, 2021
Submission concerning change of applicant's representative
Feb 12, 2021
Composition of the board (T)
Oct 23, 2020
F3345 Forwarding of submissions to parties
Oct 19, 2020
(Electronic) Receipt
Oct 19, 2020
Amended claims with annotations
Oct 19, 2020
Annexes (other than cited documents) regarding appeal procedure
Oct 19, 2020
Annexes (other than cited documents) regarding appeal procedure
Oct 19, 2020
Auxiliary request during appeals procedure - 01
Oct 19, 2020
Auxiliary request during appeals procedure - 02
Oct 19, 2020
Auxiliary request during appeals procedure - 03
Oct 19, 2020
Auxiliary request during appeals procedure - 04
Oct 19, 2020
Auxiliary request during appeals procedure - 05
Oct 19, 2020
Auxiliary request during appeals procedure - 06
Oct 19, 2020
Auxiliary request during appeals procedure - 07
Oct 19, 2020
Auxiliary request during appeals procedure - 08
Oct 19, 2020
Auxiliary request during appeals procedure - 09
Oct 19, 2020
Auxiliary request during appeals procedure - 10
Oct 19, 2020
Auxiliary request during appeals procedure - 11
Oct 19, 2020
Auxiliary request during appeals procedure - 12
Oct 19, 2020
Auxiliary request during appeals procedure - 13
Oct 19, 2020
Auxiliary request during appeals procedure - 14
Oct 19, 2020
Auxiliary request during appeals procedure - 15
Oct 19, 2020
Auxiliary request during appeals procedure - 16
Oct 19, 2020
Auxiliary request during appeals procedure - 17
Oct 19, 2020
Auxiliary request during appeals procedure - 18
Oct 19, 2020
Auxiliary request during appeals procedure - 19
Oct 19, 2020
Auxiliary request during appeals procedure - 20
Oct 19, 2020
Auxiliary request during appeals procedure - 21
Oct 19, 2020
Auxiliary request during appeals procedure - 22
Oct 19, 2020
Auxiliary request during appeals procedure - 23
Oct 19, 2020
Auxiliary request during appeals procedure - 24
Oct 19, 2020
Auxiliary request during appeals procedure - 25
Oct 19, 2020
Claims
Oct 19, 2020
Letter accompanying subsequently filed items
Oct 19, 2020
Reply to appeal
Jun 8, 2020
F3344 Setting time limit for reply/ file observations to appeal (inter partes)
May 29, 2020
(Electronic) Receipt
May 29, 2020
Cited document during appeal procedure
May 29, 2020
Cited document during appeal procedure
May 29, 2020
Cited document during appeal procedure
May 29, 2020
Cited document during appeal procedure
May 29, 2020
Letter accompanying subsequently filed items
May 29, 2020
Statement of grounds of appeal
Mar 23, 2020
F3204 Communication of the file number to the parties
Mar 19, 2020
Brief communication - Opposition proceedings
Mar 19, 2020
Communication of amended entries
Mar 19, 2020
Communication of amended entries
Mar 16, 2020
(Electronic) Receipt
Mar 16, 2020
Letter accompanying subsequently filed items
Mar 16, 2020
Notice of appeal
Mar 12, 2020
(Electronic) Receipt
Mar 12, 2020
Letter accompanying subsequently filed items
Mar 12, 2020
Request for change of opponent's representative
Jan 31, 2020
Advice of delivery
Jan 28, 2020
(Electronic) Receipt
Jan 28, 2020
Advice of delivery
Jan 28, 2020
Letter accompanying subsequently filed items
Jan 21, 2020
Acknowledgement of a document
Jan 21, 2020
Acknowledgement of a document
Jan 21, 2020
Annex to the communication - opposition
Jan 21, 2020
Decision of the Opposition Division and instruction
Jan 21, 2020
Grounds for the decision (Annex) - opposition
Jan 21, 2020
Interlocutory decision in opposition proceedings
Jan 21, 2020
Internal form - Opposition/addressees
Jan 21, 2020
Internal form - Opposition/addressees
Jan 21, 2020
Means of redress
Jan 21, 2020
Minutes of the oral proceedings (Opposition Division) - conclusion of the proceedings
Jan 21, 2020
Minutes of the oral proceedings (Opposition Division) - conclusion of the proceedings
Jan 21, 2020
Minutes of the oral proceedings (Opposition Division) - introduction of the parties
Jan 21, 2020
OPPODREX with handwritten amendments
Jan 21, 2020
Provision of a copy of the minutes - opposition procedure
Jan 21, 2020
Scanned annex to a communication - opposition procedure
Jan 21, 2020
Scanned annex to a communication - opposition procedure
Nov 6, 2019
Information about the result of oral proceedings
Oct 16, 2019
Brief communication - Opposition proceedings
Oct 11, 2019
(Electronic) Receipt
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Amended claims with annotations
Oct 11, 2019
Any annexes (other than citation) to an opposition letter
Oct 11, 2019
Citation in opposition procedure - 050
Oct 11, 2019
Citation in opposition procedure - 051
Oct 11, 2019
Citation in opposition procedure - 052
Oct 11, 2019
Citation in opposition procedure - 053
Oct 11, 2019
Claims
Oct 11, 2019
Claims
Oct 11, 2019
Claims
Oct 11, 2019
Claims
Oct 11, 2019
Claims
Oct 11, 2019
Claims
Oct 11, 2019
Claims
Oct 11, 2019
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Oct 11, 2019
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Oct 11, 2019
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Oct 11, 2019
Claims
Oct 11, 2019
Claims
Oct 11, 2019
Claims
Oct 11, 2019
Claims
Oct 11, 2019
Claims
Oct 11, 2019
Claims
Oct 11, 2019
Consolidated list of cited opposition documents
Oct 11, 2019
Letter accompanying subsequently filed items
Oct 11, 2019
Written submission in preparation to/during oral proceedings
Sep 12, 2019
Brief communication - Opposition proceedings
Sep 11, 2019
Brief communication - Opposition proceedings
Sep 9, 2019
Consolidated list of cited opposition documents
Sep 6, 2019
(Electronic) Receipt
Sep 6, 2019
(Electronic) Receipt
Sep 6, 2019
Amended claims with annotations
Sep 6, 2019
Amended claims with annotations
Sep 6, 2019
Amended claims with annotations
Sep 6, 2019
Amended claims with annotations
Sep 6, 2019
Brief communication - Opposition proceedings
Sep 6, 2019
Citation in opposition procedure - 025
Sep 6, 2019
Citation in opposition procedure - 026
Sep 6, 2019
Citation in opposition procedure - 027
Sep 6, 2019
Citation in opposition procedure - 028
Sep 6, 2019
Citation in opposition procedure - 029
Sep 6, 2019
Citation in opposition procedure - 030
Sep 6, 2019
Citation in opposition procedure - 031
Sep 6, 2019
Citation in opposition procedure - 032
Sep 6, 2019
Citation in opposition procedure - 033
Sep 6, 2019
Citation in opposition procedure - 034
Sep 6, 2019
Citation in opposition procedure - 035
Sep 6, 2019
Citation in opposition procedure - 036
Sep 6, 2019
Citation in opposition procedure - 037
Sep 6, 2019
Citation in opposition procedure - 038
Sep 6, 2019
Citation in opposition procedure - 039
Sep 6, 2019
Citation in opposition procedure - 039
Sep 6, 2019
Citation in opposition procedure - 040
Sep 6, 2019
Citation in opposition procedure - 041
Sep 6, 2019
Citation in opposition procedure - 042
Sep 6, 2019
Citation in opposition procedure - 043
Sep 6, 2019
Citation in opposition procedure - 044
Sep 6, 2019
Citation in opposition procedure - 044
Sep 6, 2019
Citation in opposition procedure - 045
Sep 6, 2019
Citation in opposition procedure - 046
Sep 6, 2019
Citation in opposition procedure - 047
Sep 6, 2019
Citation in opposition procedure - 048
Sep 6, 2019
Citation in opposition procedure - 049
Sep 6, 2019
Claims
Sep 6, 2019
Claims
Sep 6, 2019
Claims
Sep 6, 2019
Claims
Sep 6, 2019
Communication of amended entries
Sep 6, 2019
Communication of amended entries
Sep 6, 2019
Letter accompanying subsequently filed items
Sep 6, 2019
Letter accompanying subsequently filed items
Sep 6, 2019
Oral proceedings: reply to date proposed
Sep 6, 2019
Request for interpreters during oral proceedings
Sep 6, 2019
Written submission in preparation to/during oral proceedings
Sep 2, 2019
(Electronic) Receipt
Sep 2, 2019
Letter accompanying subsequently filed items
Sep 2, 2019
Request for change of opponent's representative
Aug 14, 2019
Communication of the registration of a transfer or change of name and/or address
Aug 7, 2019
Submission concerning change of applicant's address
Mar 28, 2019
Advice of delivery
Mar 28, 2019
Advice of delivery
Mar 22, 2019
Advice of delivery
Mar 20, 2019
Advice of delivery
Mar 19, 2019
Acknowledgement of a document
Mar 19, 2019
Acknowledgement of a document
Mar 19, 2019
Annex to the communication - opposition
Mar 19, 2019
Information concerning oral proceedings
Mar 19, 2019
Summons to attend oral proceedings
Mar 19, 2019
Summons to attend oral proceedings
Oct 18, 2018
Brief communication - Opposition proceedings
Oct 11, 2018
(Electronic) Receipt
Oct 11, 2018
Amended claims with annotations
Oct 11, 2018
Amended claims with annotations
Oct 11, 2018
Amended claims with annotations
Oct 11, 2018
Amended claims with annotations
Oct 11, 2018
Amended claims with annotations
Oct 11, 2018
Amended claims with annotations
Oct 11, 2018
Citation in opposition procedure - 009
Oct 11, 2018
Citation in opposition procedure - 010
Oct 11, 2018
Citation in opposition procedure - 011
Oct 11, 2018
Citation in opposition procedure - 012
Oct 11, 2018
Citation in opposition procedure - 013
Oct 11, 2018
Citation in opposition procedure - 014
Oct 11, 2018
Citation in opposition procedure - 015
Oct 11, 2018
Citation in opposition procedure - 016
Oct 11, 2018
Citation in opposition procedure - 017
Oct 11, 2018
Citation in opposition procedure - 018
Oct 11, 2018
Citation in opposition procedure - 019
Oct 11, 2018
Citation in opposition procedure - 020
Oct 11, 2018
Citation in opposition procedure - 021
Oct 11, 2018
Citation in opposition procedure - 022
Oct 11, 2018
Citation in opposition procedure - 023
Oct 11, 2018
Citation in opposition procedure - 024
Oct 11, 2018
Claims
Oct 11, 2018
Claims
Oct 11, 2018
Claims
Oct 11, 2018
Claims
Oct 11, 2018
Claims
Oct 11, 2018
Claims
Oct 11, 2018
Letter accompanying subsequently filed items
Oct 11, 2018
Reply of the patent proprietor to the notice(s) of opposition
Jun 1, 2018
Communication of a notice of opposition and request to file observations
Jun 1, 2018
Notice of further oppositions to opponent(s)
May 22, 2018
Communication of a notice of opposition - first information to patent proprietor
May 16, 2018
(Electronic) Receipt
May 16, 2018
Citation in opposition procedure - 001
May 16, 2018
Citation in opposition procedure - 002
May 16, 2018
Citation in opposition procedure - 003
May 16, 2018
Citation in opposition procedure - 004
May 16, 2018
Citation in opposition procedure - 005
May 16, 2018
Citation in opposition procedure - 006
May 16, 2018
Citation in opposition procedure - 007
May 16, 2018
Citation in opposition procedure - 008
May 16, 2018
Notice of opposition
May 16, 2018
Notice of opposition
Oct 26, 2017
Communication confirming withdrawal from representation
Oct 26, 2017
Communication of amended entries concerning the representative
Sep 26, 2017
(Electronic) Receipt
Sep 26, 2017
Letter accompanying subsequently filed items
Sep 26, 2017
Submission concerning change of applicant's representative
Aug 17, 2017
Transmission of the certificate for a European patent pursuant to Rule 74 EPC
Jul 20, 2017
Decision to grant a European patent
Jul 3, 2017
(Electronic) Receipt
Jul 3, 2017
Filing of the translations of the claims
Jul 3, 2017
French translation of claims
Jul 3, 2017
German translation of the claims
Jul 3, 2017
Letter accompanying subsequently filed items
Mar 24, 2017
Bibliographic data of the European patent application
Mar 24, 2017
Communication about intention to grant a European patent
Mar 24, 2017
Intention to grant (signatures)
Mar 24, 2017
Text intended for grant (clean copy)
Mar 24, 2017
Text intended for grant (version for approval)
Jun 3, 2016
(Electronic) Receipt
Jun 3, 2016
Claims
Jun 3, 2016
Description
Jun 3, 2016
Letter accompanying subsequently filed items
Jun 3, 2016
Reply to communication from the Examining Division
Apr 1, 2016
Annex to the communication
Apr 1, 2016
Consultation by telephone/in person (with time limit)
Apr 1, 2016
Result of consultation by telephone/in person
May 18, 2015
Communication concerning corrected entries of the applicant
May 11, 2015
Submission concerning representation
May 8, 2015
Communication of the registration of a transfer or change of name and/or address
May 8, 2015
Submission concerning representation
Apr 21, 2015
Submission concerning change of applicant's address
Oct 31, 2014
(Electronic) Receipt
Oct 31, 2014
Amended claims with annotations
Oct 31, 2014
Amended description with annotations
Oct 31, 2014
Claims
Oct 31, 2014
Description
Oct 31, 2014
Letter accompanying subsequently filed items
Oct 31, 2014
Reply to communication from the Examining Division
Jun 27, 2014
Annex to the communication
Jun 27, 2014
Communication from the Examining Division
Jun 3, 2014
Examination started
Apr 7, 2014
(Electronic) Receipt
Apr 7, 2014
Enquiry as to when a communication from the Examining Division can be expected
Apr 7, 2014
Letter accompanying subsequently filed items
Mar 18, 2011
(Electronic) Receipt
Mar 18, 2011
Amended claims filed after receipt of (European) search report
Mar 18, 2011
Amendments received before examination
Mar 18, 2011
Letter accompanying subsequently filed items
Sep 14, 2010
Invitation to declare maintenance of the application and to correct deficiencies in the Written Opinion/amend application
Aug 27, 2010
Communication regarding the transmission of the European search report
Aug 27, 2010
European search opinion
Aug 27, 2010
Supplementary European search report
Jul 24, 2009
Amended claims filed after receipt of (European) search report
Jul 24, 2009
Amendments received before examination
Jul 22, 2009
Amended claims filed after receipt of (European) search report
Jul 22, 2009
Amendments received before examination
Jul 22, 2009
Notification on forthcoming publication of bibliographic data
Jun 18, 2009
Communication regarding possible amendment of claims/payment of claims fees
Jun 5, 2009
Request for entry into the European phase
Jun 3, 2009
Fax request to enter the European phase
Jun 3, 2009
Payment of fees and costs
Jun 3, 2009
Payment of fees and costs
May 19, 2009
Copy of the international preliminary report on patentability
Apr 9, 2009
Information on entry into European phase
Nov 6, 2008
Copy of the international search report
Nov 6, 2008
International publication of the international search report
Jun 25, 2008
Priority document (electronically transmitted)
Jun 5, 2008
Published international application - A2

EP2088864

THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

Application Number: EP07871350A
Filing Date: Nov 2, 2007
Status: Patent Maintained As Amended; Jul 25, 2025
Publication Date: Aug 27, 2025
External Links: Slate, EP2088864B2, Google Patents