Sglt-2 Inhibitor For Treating Type 1 Diabetes Mellitus, Type 2 Diabete Mellitus, Impaired Glucose Tolerance Or Hyperglycemia

Patent No. EP2396005 (titled "Sglt-2 Inhibitor For Treating Type 1 Diabetes Mellitus, Type 2 Diabete Mellitus, Impaired Glucose Tolerance Or Hyperglycemia") was filed by Boehringer Ingelheim on Feb 11, 2010. The application was issued on Nov 26, 2025.

Patent Summary

The SGLT2 inhibitor 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((S)-tetrahydrofuran-3-yloxy)-benzyl]-benzene is used in a method to improve glycemic control in patients with type 2 diabetes mellitus. The treatment consists of a pharmaceutical composition administered orally as a monotherapy. The specific dosage strength is 10 mg, administered once daily. The inhibitor functions by decreasing the renal reuptake threshold of glucose, thereby increasing glucose excretion in urine to lower blood glucose concentrations. Broadly, the inhibitor is indicated for treating metabolic disorders (including type 1 and 2 diabetes, obesity, and metabolic syndrome), preventing diabetes-related micro- and macrovascular complications, reducing body weight, restoring pancreatic beta-cell functionality, treating hyperuricemia, and managing hyponatremia or kidney stones.

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Patent Oppositions (20)

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Dossier Documents

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EP2396005

BOEHRINGER INGELHEIM
Application Number
EP10703287A
Filing Date
Feb 11, 2010
Status
Granted And Under Opposition
Oct 24, 2025
Publication Date
Nov 26, 2025