IP Verse

Variant Immunoglobulins With Improved Manufacturability

Patent No. EP2467400 (titled "Variant Immunoglobulins With Improved Manufacturability") was filed by Lonza Biologics on Aug 20, 2010. The application was issued on Jan 24, 2018.

Patent Summary

A method for improving manufacturability of antibody molecules by reducing aggregation propensity through targeted amino acid substitutions in specific regions of the immunoglobulin structure. The method identifies aggregation-prone segments in the variable and constant domains of the antibody and introduces specific substitutions at these positions to enhance stability and reduce aggregation during production and formulation processes.

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Patent Family

Patent Oppositions (2)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
STRAWMANOct 24, 2018VOSSIUS & PARTNER PATENTANWALTE RECHTSANWALTE MBB
WHITEOct 24, 2018BOULT WADE TENNANT

Dossier Documents

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EP2467400

LONZA BIOLOGICS
Application Number
EP10749484A
Filing Date
Aug 20, 2010
Status
Revoked
Jul 3, 2020
Publication Date
Jan 24, 2018
External Links
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