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Selective Sphingosine 1 Phosphate Receptor Modulators And Methods Of Chiral Synthesis

Patent No. EP2498610 (titled "Selective Sphingosine 1 Phosphate Receptor Modulators And Methods Of Chiral Synthesis") was filed by Celgene II on Nov 15, 2010. The application was issued on Jun 19, 2024.

Patent Summary

Compounds that selectively activate the sphingosine 1-phosphate receptor subtype 1 (S1P1) for treating inflammatory bowel disease (IBD) and other conditions, including multiple sclerosis, transplant rejection, and acute respiratory distress syndrome. The compounds have a specific indane or oxadiazole-indane structure and are synthesized through a chiral synthesis method that produces enantiomerically enriched compounds.

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

Company	Opposition Date	Representative
GENERICS UK	Dec 14, 2018	ELKINGTON AND FIFE

Dossier Documents

The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.

Date
Description

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May 24, 2024
Decision to maintain the European patent in amended form
May 24, 2024
Decision to maintain the European patent in amended form
May 15, 2024
(Electronic) Receipt
May 15, 2024
Description
May 15, 2024
Druckexemplar in opposition procedure
May 15, 2024
Filing of the translation of the amended claims
May 15, 2024
French translation of claims
May 15, 2024
German translation of the claims
May 15, 2024
Letter accompanying subsequently filed items
Feb 21, 2024
Communication of bibliographic data
Feb 21, 2024
Communication to opponent concerning maintenance
Feb 21, 2024
Communication with request to file translations
Feb 16, 2024
Brief communication - Opposition proceedings
Feb 16, 2024
Brief communication - Opposition proceedings
Feb 16, 2024
Communication of the registration of a transfer or change of name and/or address
Feb 16, 2024
Maintenance of the patent with the documents specified in the final decision
Feb 13, 2024
(Electronic) Receipt
Feb 13, 2024
Annexes in respect of a client data request
Feb 13, 2024
Annexes in respect of a client data request
Feb 13, 2024
Annexes in respect of a client data request
Feb 13, 2024
Authorisation
Feb 13, 2024
Letter accompanying subsequently filed items
Feb 13, 2024
Submission concerning change of proprietor's address
Jan 9, 2024
Decision of the Board of Appeal
Jan 9, 2024
F3032 Notification(s) of the decision
Jan 9, 2024
F3032 Notification(s) of the decision
Jan 9, 2024
Maintenance of the patent with the documents specified in the final decision
Oct 11, 2023
F3013 Oral Proceedings: Forwarding minutes
Oct 11, 2023
F3013 Oral Proceedings: Forwarding minutes
Oct 11, 2023
F3316 Oral Proceedings: Minutes (Appellant: Opponent)
Aug 11, 2023
(Electronic) Receipt
Aug 9, 2023
F3345 Forwarding of submissions to parties
Aug 8, 2023
F3345 Forwarding of submissions to parties
Aug 4, 2023
(Electronic) Receipt
Aug 4, 2023
Letter accompanying subsequently filed items
Aug 4, 2023
Letter dealing with oral proceedings during the appeal procedure
Aug 2, 2023
(Electronic) Receipt
Aug 2, 2023
Letter accompanying subsequently filed items
Aug 2, 2023
Letter dealing with oral proceedings during the appeal procedure
Jul 14, 2023
F3305 Communication of the Board of Appeal (ex parte/ inter partes)
Jul 14, 2023
F3305 Communication of the Board of Appeal (ex parte/ inter partes)
May 3, 2023
Oral proceedings: change of venue
May 3, 2023
Oral proceedings: change of venue
Apr 13, 2023
F3345 Forwarding of submissions to parties
Apr 6, 2023
(Electronic) Receipt
Apr 6, 2023
Letter dealing with oral proceedings during the appeal procedure
Apr 6, 2023
Letter regarding the opposition procedure (no time limit)
Dec 8, 2022
F3004 Communication of the Registry
Dec 8, 2022
F3004 Communication of the Registry
Dec 8, 2022
F3011.1 Oral Proceedings: summons
Dec 8, 2022
F3011.1 Oral Proceedings: summons
Dec 5, 2022
F3010 Oral proceedings: order for summons
Aug 13, 2021
Communication of amended entries concerning the representative
May 3, 2021
F3345 Forwarding of submissions to parties
Apr 28, 2021
Consolidated list of documents cited in appeal procedure
Apr 27, 2021
(Electronic) Receipt
Apr 27, 2021
Any annexes (other than citation) to an opposition letter
Apr 27, 2021
Citation in appeal procedure - 025
Apr 27, 2021
Citation in appeal procedure - 026
Apr 27, 2021
Citation in appeal procedure - 027
Apr 27, 2021
Letter regarding the opposition procedure (no time limit)
Apr 27, 2021
Letter relating to Appeal Procedure
Apr 27, 2021
Letter relating to Appeal Procedure
Dec 18, 2020
F3345 Forwarding of submissions to parties
Dec 15, 2020
(Electronic) Receipt
Dec 15, 2020
Letter accompanying subsequently filed items
Dec 15, 2020
Letter relating to Appeal Procedure
Dec 15, 2020
Letter relating to Appeal Procedure
Dec 15, 2020
Letter relating to Appeal Procedure
Oct 12, 2020
Communication of the registration of a transfer or change of name and/or address
Oct 5, 2020
(Electronic) Receipt
Oct 5, 2020
Annexes in respect of a client data request
Oct 5, 2020
Annexes in respect of a client data request
Oct 5, 2020
Annexes in respect of a client data request
Oct 5, 2020
Letter accompanying subsequently filed items
Oct 5, 2020
Submission concerning a transfer of rights (proprietor)
Oct 1, 2020
F3345 Forwarding of submissions to parties
Sep 25, 2020
(Electronic) Receipt
Sep 25, 2020
Citation in appeal procedure - 021
Sep 25, 2020
Citation in appeal procedure - 022
Sep 25, 2020
Citation in appeal procedure - 023
Sep 25, 2020
Citation in appeal procedure - 024
Sep 25, 2020
Claims
Sep 25, 2020
Letter accompanying subsequently filed items
Sep 25, 2020
Letter relating to Appeal Procedure
Sep 25, 2020
Reply to appeal
Sep 25, 2020
Reply to appeal
Jun 15, 2020
Composition of the board (T)
May 20, 2020
F3204 Communication of the file number to the parties
May 20, 2020
F3204 Communication of the file number to the parties
May 20, 2020
F3344 Setting time limit for reply/ file observations to appeal (inter partes)
May 12, 2020
(Electronic) Receipt
May 12, 2020
Citation in appeal procedure - 020
May 12, 2020
Letter accompanying subsequently filed items
May 12, 2020
Notice of appeal
May 12, 2020
Statement of grounds of appeal
Mar 27, 2020
Advice of delivery
Mar 10, 2020
Advice of delivery
Mar 10, 2020
Advice of delivery
Mar 6, 2020
Acknowledgement of a document
Mar 6, 2020
Acknowledgement of a document
Mar 6, 2020
Annex to the communication - opposition
Mar 6, 2020
Decision of the Opposition Division and instruction
Mar 6, 2020
Grounds for the decision (Annex) - opposition
Mar 6, 2020
Interlocutory decision in opposition proceedings
Mar 6, 2020
Internal form - Opposition/addressees
Mar 6, 2020
Internal form - Opposition/addressees
Mar 6, 2020
Means of redress
Mar 6, 2020
Minutes of the oral proceedings (Opposition Division) - conclusion of the proceedings
Mar 6, 2020
Minutes of the oral proceedings (Opposition Division) - conclusion of the proceedings
Mar 6, 2020
Minutes of the oral proceedings (Opposition Division) - introduction of the parties
Mar 6, 2020
OPPODREX with handwritten amendments
Mar 6, 2020
Provision of a copy of the minutes - opposition procedure
Mar 6, 2020
Scanned annex to a communication - opposition procedure
Feb 3, 2020
Information about the result of oral proceedings
Dec 9, 2019
Brief communication - Opposition proceedings
Dec 5, 2019
Brief communication - Opposition proceedings
Dec 3, 2019
(Electronic) Receipt
Dec 3, 2019
Letter accompanying subsequently filed items
Dec 3, 2019
Written submission in preparation to/during oral proceedings
Dec 2, 2019
(Electronic) Receipt
Dec 2, 2019
Letter accompanying subsequently filed items
Dec 2, 2019
Written submission in preparation to/during oral proceedings
Oct 2, 2019
Brief communication - Opposition proceedings
Sep 23, 2019
(Electronic) Receipt
Sep 23, 2019
Letter accompanying subsequently filed items
Sep 23, 2019
Request for interpreters during oral proceedings
Jul 10, 2019
Advice of delivery
Jul 10, 2019
Advice of delivery
Jun 28, 2019
Advice of delivery
Jun 27, 2019
Advice of delivery
Jun 21, 2019
Acknowledgement of a document
Jun 21, 2019
Acknowledgement of a document
Jun 21, 2019
Annex to the communication - opposition
Jun 21, 2019
Information concerning oral proceedings
Jun 21, 2019
Summons to attend oral proceedings
Jun 21, 2019
Summons to attend oral proceedings
May 17, 2019
Brief communication - Opposition proceedings
May 14, 2019
Consolidated list of cited opposition documents
May 13, 2019
(Electronic) Receipt
May 13, 2019
Citation in opposition procedure - 007
May 13, 2019
Citation in opposition procedure - 008
May 13, 2019
Citation in opposition procedure - 009
May 13, 2019
Citation in opposition procedure - 010
May 13, 2019
Citation in opposition procedure - 011
May 13, 2019
Citation in opposition procedure - 012
May 13, 2019
Citation in opposition procedure - 013
May 13, 2019
Citation in opposition procedure - 014
May 13, 2019
Citation in opposition procedure - 015
May 13, 2019
Citation in opposition procedure - 016
May 13, 2019
Citation in opposition procedure - 017
May 13, 2019
Citation in opposition procedure - 018
May 13, 2019
Claims
May 13, 2019
Letter accompanying subsequently filed items
May 13, 2019
Reply of the patent proprietor to the notice(s) of opposition
Jan 17, 2019
Brief communication - Opposition proceedings
Jan 17, 2019
Communication confirming withdrawal from representation
Jan 17, 2019
Communication of amended entries concerning the representative
Jan 14, 2019
Submission concerning change of applicant's representative
Jan 4, 2019
Communication of a notice of opposition and request to file observations
Jan 4, 2019
Notice of further oppositions to opponent(s)
Jan 2, 2019
Communication of a notice of opposition - first information to patent proprietor
Dec 14, 2018
(Electronic) Receipt
Dec 14, 2018
Citation in opposition procedure - 001
Dec 14, 2018
Citation in opposition procedure - 002
Dec 14, 2018
Citation in opposition procedure - 003
Dec 14, 2018
Citation in opposition procedure - 004
Dec 14, 2018
Citation in opposition procedure - 005
Dec 14, 2018
Citation in opposition procedure - 006
Dec 14, 2018
Notice of opposition
Dec 14, 2018
Notice of opposition
Mar 26, 2018
Transmission of the certificate for a European patent pursuant to Rule 74 EPC
Feb 15, 2018
Decision to grant a European patent
Jan 30, 2018
(Electronic) Receipt
Jan 30, 2018
Filing of the translations of the claims
Jan 30, 2018
French translation of claims
Jan 30, 2018
German translation of the claims
Jan 30, 2018
Letter accompanying subsequently filed items
Sep 27, 2017
Bibliographic data of the European patent application
Sep 27, 2017
Communication about intention to grant a European patent
Sep 27, 2017
Intention to grant (signatures)
Sep 27, 2017
Text intended for grant (clean copy)
Sep 27, 2017
Text intended for grant (version for approval)
Aug 29, 2017
Processing of request for correction of text proposed for grant or third party observations (from 01-04-2012)
Jul 26, 2017
(Electronic) Receipt
Jul 26, 2017
Description
Jul 26, 2017
Letter accompanying subsequently filed items
Jul 26, 2017
Request for correction/amendment of the text proposed for grant sent from 01.04.2012
Apr 20, 2017
Refund of fees
Apr 18, 2017
Bibliographic data of the European patent application
Apr 18, 2017
Communication about intention to grant a European patent
Apr 18, 2017
Intention to grant (signatures)
Apr 18, 2017
Text intended for grant (clean copy)
Apr 18, 2017
Text intended for grant (version for approval)
Apr 11, 2017
Communication of the registration of a transfer or change of name and/or address
Mar 31, 2017
Annexes in respect of a client data request
Mar 31, 2017
Annexes in respect of a client data request
Mar 31, 2017
Payment of fees and costs
Mar 31, 2017
Payment of fees and costs
Mar 31, 2017
Payment of fees and costs
Mar 31, 2017
Submission concerning a transfer of rights (applicant)
Dec 23, 2016
Brief communication to applicant/representative
Dec 16, 2016
Annexes in respect of a client data request
Dec 16, 2016
Letter accompanying subsequently filed items
Dec 16, 2016
Submission concerning change of applicant's name
Apr 8, 2016
(Electronic) Receipt
Apr 8, 2016
Amended description with annotations
Apr 8, 2016
Claims
Apr 8, 2016
Description
Apr 8, 2016
Letter accompanying subsequently filed items
Apr 8, 2016
Reply to communication from the Examining Division
Dec 16, 2015
Annex to the communication
Dec 16, 2015
Annex to the communication
Dec 16, 2015
Communication from the Examining Division
Dec 16, 2015
Consultation by telephone/in person
Dec 16, 2015
Result of consultation by telephone/in person
Nov 2, 2015
(Electronic) Receipt
Nov 2, 2015
Amended claims with annotations
Nov 2, 2015
Claims
Nov 2, 2015
Letter accompanying subsequently filed items
Nov 2, 2015
Reply to communication from the Examining Division
Jun 23, 2015
Annex to the communication
Jun 23, 2015
Communication from the Examining Division
Jun 16, 2015
Examination started
Apr 16, 2015
Response to enquiry for communication from the Examining Division
Apr 8, 2015
Enquiry as to when a communication from the Examining Division can be expected
Feb 19, 2015
CDS Clean up - amended data concerning the representative of the applicant (Association)
Feb 9, 2015
Submission concerning representation
Dec 12, 2013
CDS Clean up - amended data concerning the representative of the applicant (Association)
Nov 12, 2013
(Electronic) Receipt
Nov 12, 2013
Amended claims filed after receipt of (European) search report
Nov 12, 2013
Amendments received before examination
Nov 12, 2013
Letter accompanying subsequently filed items
May 10, 2013
Invitation to declare maintenance of the application and to correct deficiencies in the Written Opinion/amend application
Apr 22, 2013
Communication regarding the transmission of the European search report
Apr 22, 2013
European search opinion
Apr 22, 2013
Supplementary European search report
Aug 22, 2012
Notification on forthcoming publication of bibliographic data
Aug 14, 2012
Letter which had not been notified
Aug 3, 2012
Refund of fees
Jul 13, 2012
Communication regarding possible amendment of the application/payment of claims fee
Jun 6, 2012
(Electronic) Receipt
Jun 6, 2012
Amended claims filed after receipt of (European) search report
Jun 6, 2012
Amendments received before examination
Jun 6, 2012
Request for entry into the European phase
Jun 1, 2012
Copy of the international preliminary report on patentability
Mar 23, 2012
Information on entry into European phase
Jun 9, 2011
Priority document (electronically transmitted)
Jun 9, 2011
Priority document (electronically transmitted)
May 19, 2011
Copy of the international search report
May 19, 2011
Published international application - A1

EP2498610

CELGENE II

Application Number: EP10830880A
Filing Date: Nov 15, 2010
Status: Patent Maintained As Amended; May 17, 2024
Publication Date: Jun 19, 2024
External Links: Slate, Register , Google Patents