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Generation Of Induced Pluripotent Stem Cells From Small Volumes Of Peripheral Blood

Patent No. EP2582794 (titled "Generation Of Induced Pluripotent Stem Cells From Small Volumes Of Peripheral Blood") was filed by Cellular Dynamics on Jun 14, 2011. The application was issued on Apr 24, 2024.

Patent Summary

Efficiently reprogramming peripheral blood cells into induced pluripotent stem cells (iPS) without using viruses, feeder layers, or xenogeneic components. The method involves culturing and expanding hematopoietic progenitor cells from a small blood sample, then reprogramming them using defined conditions with specific transcription factors and inhibitors. The reprogrammed iPS cells can be selected and expanded further using chemically defined media. This allows generating patient-specific iPS cells from blood using scalable, clinical-grade methods.

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Patent Family

Patent Oppositions (4)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
JAMES POOLEDec 7, 2018CARPMAELS & RANSFORD
MATHYS & SQUIREDec 7, 2018GREGSON
LONZA WALKERSVILLEDec 7, 2018EDER
STRAWMANDec 7, 2018MEWBURN ELLIS

Dossier Documents

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EP2582794

CELLULAR DYNAMICS
Application Number
EP11796290A
Filing Date
Jun 14, 2011
Status
Patent Maintained As Amended
Mar 22, 2024
Publication Date
Apr 24, 2024
External Links
Slate, EP2582794B2, Google Patents