Inhibitors Of Human Ezh2, And Methods Of Use Thereof

Patent No. EP2614369 (titled "Inhibitors Of Human Ezh2, And Methods Of Use Thereof") was filed by Epizyme on Sep 12, 2011. The application was issued on May 28, 2025.

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

Company	Opposition Date	Representative
GLAXOSMITHKLINE	Nov 2, 2016	FOWLER

Dossier Documents

The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.

Date
Description

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May 2, 2025
Decision to maintain the European patent in amended form
May 2, 2025
Decision to maintain the European patent in amended form
Apr 17, 2025
(Electronic) Receipt
Apr 17, 2025
Filing of the translation of the amended claims
Apr 17, 2025
French translation of claims
Apr 17, 2025
German translation of the claims
Apr 17, 2025
Letter accompanying subsequently filed items
Mar 3, 2025
Communication concerning surcharge and failure to observe time limit
Oct 25, 2024
Communication of bibliographic data
Oct 25, 2024
Communication to opponent concerning maintenance
Oct 25, 2024
Communication with request to file translations
Oct 18, 2024
Maintenance of the patent with the documents specified in the final decision
Sep 23, 2024
Letter accompanying subsequently filed items
Sep 23, 2024
Request concerning representative opponent
Jun 21, 2024
Brief communication - Opposition proceedings
Jun 21, 2024
Brief communication - Opposition proceedings
Jun 21, 2024
Decision of the Opposition Division and instruction
Jun 21, 2024
Druckexemplar in opposition procedure
Jun 21, 2024
Grounds for the decision (Annex) - opposition
Jun 21, 2024
Interlocutory decision in opposition proceedings
Jun 21, 2024
Interlocutory decision in opposition proceedings
Jun 21, 2024
Means of redress
Apr 3, 2024
Brief communication - Opposition proceedings
Mar 27, 2024
(Electronic) Receipt
Mar 27, 2024
Letter accompanying subsequently filed items
Mar 27, 2024
Reply to an examination report in opposition proceedings
Mar 1, 2024
Brief communication - Opposition proceedings
Mar 1, 2024
Brief communication - Opposition proceedings
Mar 1, 2024
Brief communication - Opposition proceedings
Mar 1, 2024
Brief communication - Opposition proceedings
Mar 1, 2024
Communication inviting the parties to file observations
Mar 1, 2024
Communication inviting the parties to file observations
Feb 7, 2024
Brief communication - Opposition proceedings
Feb 1, 2024
(Electronic) Receipt
Feb 1, 2024
Letter accompanying subsequently filed items
Feb 1, 2024
Letter regarding the opposition procedure (no time limit)
Jan 25, 2024
Brief communication - Opposition proceedings
Jan 25, 2024
Brief communication - Opposition proceedings
Jan 25, 2024
Communication inviting the parties to file observations
Jan 25, 2024
Communication inviting the parties to file observations
Jan 24, 2024
Request for change of opponent's representative
Dec 1, 2023
Brief communication - Opposition proceedings
Nov 27, 2023
(Electronic) Receipt
Nov 27, 2023
Amended description with annotations
Nov 27, 2023
Description
Nov 27, 2023
Letter accompanying subsequently filed items
Nov 27, 2023
Reply to an examination report in opposition proceedings
Jul 18, 2023
Annex to the communication - opposition
Jul 18, 2023
Brief communication - Opposition proceedings
Jul 18, 2023
Brief communication - Opposition proceedings
Jul 18, 2023
Communication inviting the parties to file observations
Jul 18, 2023
Communication inviting the parties to file observations
Jun 22, 2023
Decision of the Board of Appeal
Jun 22, 2023
F3032 Notification(s) of the decision
Jun 22, 2023
F3032 Notification(s) of the decision
May 3, 2023
F3013 Oral Proceedings: Forwarding minutes
May 3, 2023
F3013 Oral Proceedings: Forwarding minutes
May 3, 2023
F3316 Oral Proceedings: Minutes (Appellant: Opponent)
Apr 6, 2023
F3305 Communication of the Board of Appeal (ex parte/ inter partes)
Apr 6, 2023
F3305 Communication of the Board of Appeal (ex parte/ inter partes)
Apr 6, 2023
Oral proceedings: change of venue
Apr 6, 2023
Oral proceedings: change of venue
Apr 5, 2023
F3345 Forwarding of submissions to parties
Mar 30, 2023
(Electronic) Receipt
Mar 30, 2023
F3345 Forwarding of submissions to parties
Mar 30, 2023
Letter accompanying subsequently filed items
Mar 30, 2023
Letter dealing with oral proceedings during the appeal procedure
Mar 29, 2023
(Electronic) Receipt
Mar 29, 2023
Letter accompanying subsequently filed items
Mar 29, 2023
Letter dealing with oral proceedings during the appeal procedure
Feb 28, 2023
F3305 Communication of the Board of Appeal (ex parte/ inter partes)
Feb 28, 2023
F3305 Communication of the Board of Appeal (ex parte/ inter partes)
Feb 1, 2023
F3004 Communication of the Registry
Feb 1, 2023
F3004 Communication of the Registry
Jan 25, 2023
F3345 Forwarding of submissions to parties
Jan 20, 2023
(Electronic) Receipt
Jan 20, 2023
Letter accompanying subsequently filed items
Jan 20, 2023
Letter dealing with oral proceedings during the appeal procedure
Jan 3, 2023
F3004 Communication of the Registry
Jan 3, 2023
F3004 Communication of the Registry
Sep 13, 2022
Communication of amended entries in the Register of European Patents
Sep 13, 2022
F3345 Forwarding of submissions to parties
Sep 2, 2022
(Electronic) Receipt
Sep 2, 2022
Letter accompanying subsequently filed items
Sep 2, 2022
Letter dealing with oral proceedings during the appeal procedure
Jul 12, 2022
F3057 Communication: Change of responsibility of a Board of Appeal
Jul 12, 2022
F3057 Communication: Change of responsibility of a Board of Appeal
Jun 22, 2022
F3011.1 Oral Proceedings: summons
Jun 22, 2022
F3011.1 Oral Proceedings: summons
Jun 17, 2022
F3010 Oral proceedings: order for summons
Jun 17, 2022
F3350 Communication regarding oral proceedings (art. 15 Rules of Procedure of the Boards of Appeal)
May 12, 2022
F3303.16 Change of composition of the Board (T)
Oct 8, 2021
Communication of amended entries
Jun 18, 2021
Request for change of opponent's representative
Sep 17, 2019
Composition of the board (T)
Apr 15, 2019
F3345 Forwarding of submissions to parties
Apr 8, 2019
(Electronic) Receipt
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Amended claims with annotations
Apr 8, 2019
Citation in appeal procedure - 022
Apr 8, 2019
Citation in appeal procedure - 023
Apr 8, 2019
Letter accompanying subsequently filed items
Apr 8, 2019
Reply to appeal
Nov 27, 2018
F3344 Setting time limit for reply/ file observations to appeal (inter partes)
Nov 22, 2018
(Electronic) Receipt
Nov 22, 2018
Citation in appeal procedure - 020
Nov 22, 2018
Citation in appeal procedure - 021
Nov 22, 2018
Letter accompanying subsequently filed items
Nov 22, 2018
Statement of grounds of appeal
Sep 27, 2018
F3204 Communication of the file number to the parties
Sep 27, 2018
F3204 Communication of the file number to the parties
Sep 17, 2018
Processing of an appeal
Sep 14, 2018
(Electronic) Receipt
Sep 14, 2018
(Electronic) Receipt
Sep 14, 2018
Advice of delivery
Sep 14, 2018
Letter accompanying subsequently filed items
Sep 14, 2018
Letter accompanying subsequently filed items
Sep 14, 2018
Notice of appeal
Aug 21, 2018
Communication about missing advice of delivery
Jul 24, 2018
Advice of delivery
Jul 16, 2018
Acknowledgement of a document
Jul 16, 2018
Acknowledgement of a document
Jul 16, 2018
Annex to the communication - opposition
Jul 16, 2018
Decision of the Opposition Division and instruction
Jul 16, 2018
Decision rejecting the opposition
Jul 16, 2018
Grounds for the decision (Annex) - opposition
Jul 16, 2018
Internal form - Opposition/addressees
Jul 16, 2018
Internal form - Opposition/addressees
Jul 16, 2018
Minutes of the oral proceedings (Opposition Division) - conclusion of the proceedings
Jul 16, 2018
Minutes of the oral proceedings (Opposition Division) - conclusion of the proceedings
Jul 16, 2018
Minutes of the oral proceedings (Opposition Division) - introduction of the parties
Jul 16, 2018
Provision of a copy of the minutes - opposition procedure
Jul 16, 2018
Scanned annex to a communication - opposition procedure
May 17, 2018
Information about the result of oral proceedings
Mar 22, 2018
Brief communication - Opposition proceedings
Mar 21, 2018
Brief communication - Opposition proceedings
Mar 20, 2018
Brief communication - Opposition proceedings
Mar 16, 2018
(Electronic) Receipt
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Amended claims with annotations
Mar 16, 2018
Claims
Mar 16, 2018
Claims
Mar 16, 2018
Claims
Mar 16, 2018
Claims
Mar 16, 2018
Claims
Mar 16, 2018
Claims
Mar 16, 2018
Claims
Mar 16, 2018
Claims
Mar 16, 2018
Claims
Mar 16, 2018
Claims
Mar 16, 2018
Claims
Mar 16, 2018
Claims
Mar 16, 2018
Claims
Mar 16, 2018
Letter accompanying subsequently filed items
Mar 16, 2018
Oral proceedings: reply to date proposed
Mar 15, 2018
(Electronic) Receipt
Mar 15, 2018
(Electronic) Receipt
Mar 15, 2018
Citation in opposition procedure
Mar 15, 2018
Citation in opposition procedure
Mar 15, 2018
Letter accompanying subsequently filed items
Mar 15, 2018
Non-patent literature cited during the opposition procedure
Mar 15, 2018
Non-patent literature cited during the opposition procedure
Mar 15, 2018
Non-patent literature cited during the opposition procedure
Mar 15, 2018
Non-patent literature cited during the opposition procedure
Mar 15, 2018
Non-patent literature cited during the opposition procedure
Mar 15, 2018
Patent document cited during the opposition procedure
Mar 15, 2018
Request for interpreters during oral proceedings
Mar 15, 2018
Request for interpreters during oral proceedings
Mar 15, 2018
Written submission in preparation to/during oral proceedings
Oct 24, 2017
(Electronic) Receipt
Oct 24, 2017
Advice of delivery
Oct 24, 2017
Letter accompanying subsequently filed items
Oct 20, 2017
Advice of delivery
Oct 17, 2017
Acknowledgement of a document
Oct 17, 2017
Acknowledgement of a document
Oct 17, 2017
Annex to the communication - opposition
Oct 17, 2017
Information concerning oral proceedings
Oct 17, 2017
Preparation for oral proceedings
Oct 17, 2017
Summons to attend oral proceedings
Oct 17, 2017
Summons to attend oral proceedings
May 3, 2017
Brief communication - Opposition proceedings
Apr 24, 2017
(Electronic) Receipt
Apr 24, 2017
Claims
Apr 24, 2017
Claims
Apr 24, 2017
Claims
Apr 24, 2017
Claims
Apr 24, 2017
Letter accompanying subsequently filed items
Apr 24, 2017
Non-patent literature cited during the opposition procedure
Apr 24, 2017
Non-patent literature cited during the opposition procedure
Apr 24, 2017
Reply of the patent proprietor to the notice(s) of opposition
Dec 13, 2016
Communication of a notice of opposition and request to file observations
Dec 13, 2016
Notice of further oppositions to opponent(s)
Nov 9, 2016
Communication of a notice of opposition - first information to patent proprietor
Nov 2, 2016
(Electronic) Receipt
Nov 2, 2016
Citation in opposition procedure
Nov 2, 2016
Non-patent literature cited during the opposition procedure
Nov 2, 2016
Non-patent literature cited during the opposition procedure
Nov 2, 2016
Non-patent literature cited during the opposition procedure
Nov 2, 2016
Non-patent literature cited during the opposition procedure
Nov 2, 2016
Non-patent literature cited during the opposition procedure
Nov 2, 2016
Non-patent literature cited during the opposition procedure
Nov 2, 2016
Notice of opposition
Nov 2, 2016
Notice of opposition
Nov 2, 2016
Notice of opposition
Nov 2, 2016
Patent document cited during the opposition procedure
Nov 2, 2016
Patent document cited during the opposition procedure
Nov 2, 2016
Patent document cited during the opposition procedure
Feb 3, 2016
Transmission of the certificate for a European patent pursuant to Rule 74 EPC
Jan 8, 2016
Decision to grant a European patent
Nov 23, 2015
(Electronic) Receipt
Nov 23, 2015
Filing of the translations of the claims
Nov 23, 2015
French translation of claims
Nov 23, 2015
German translation of the claims
Nov 23, 2015
Letter accompanying subsequently filed items
Aug 21, 2015
Communication confirming withdrawal from representation
Aug 21, 2015
Communication of amended entries concerning the representative
Aug 3, 2015
Submission concerning change of applicant's representative
Jul 31, 2015
Submission concerning change of applicant's representative
Jul 24, 2015
Bibliographic data of the European patent application
Jul 24, 2015
Communication about intention to grant a European patent
Jul 24, 2015
Intention to grant (signatures)
Jul 24, 2015
Text intended for grant
Jul 17, 2015
Submission concerning change of applicant's representative
Mar 26, 2015
Brief communication to applicant/representative
Mar 24, 2015
Annex to the communication
Mar 24, 2015
Consultation by telephone/in person
Mar 24, 2015
Result of consultation by telephone/in person
Mar 4, 2015
Annex to the communication
Mar 4, 2015
Consultation by telephone/in person (with time limit)
Mar 4, 2015
Result of consultation by telephone/in person
Oct 29, 2014
(Electronic) Receipt
Oct 29, 2014
Amended description with annotations
Oct 29, 2014
Description
Oct 29, 2014
Letter accompanying subsequently filed items
Oct 29, 2014
Reply to communication from the Examining Division
Sep 2, 2014
Annex to the communication
Sep 2, 2014
Consultation by telephone/in person (with time limit)
Sep 2, 2014
Result of consultation by telephone/in person
Aug 27, 2014
Examination started
Jul 4, 2014
(Electronic) Receipt
Jul 4, 2014
Amended claims filed after receipt of (European) search report
Jul 4, 2014
Amended claims with annotations
Jul 4, 2014
Amendments received before examination
Jul 4, 2014
Letter accompanying subsequently filed items
Mar 20, 2014
Invitation to declare maintenance of the application and to correct deficiencies in the Written Opinion/amend application
Mar 3, 2014
Communication regarding the transmission of the European search report
Mar 3, 2014
European search opinion
Mar 3, 2014
Supplementary European search report
Feb 7, 2014
Search started
Dec 30, 2013
(Electronic) Receipt
Dec 30, 2013
Amended claims filed after receipt of (European) search report
Dec 30, 2013
Letter accompanying subsequently filed items
Dec 30, 2013
Matter concerning the application
Jun 20, 2013
Communication regarding possible amendment of the application/payment of claims fee
Jun 19, 2013
Notification on forthcoming publication of bibliographic data
Jun 17, 2013
Communication of the registration of a transfer or change of name and/or address
Jun 17, 2013
Communication to designated inventor
Jun 7, 2013
(Electronic) Receipt
Jun 7, 2013
Letter accompanying subsequently filed items
Jun 7, 2013
Letter concerning the inventor
May 28, 2013
Invitation to indicate correct address of inventor
May 14, 2013
Letter which had not been notified
Apr 24, 2013
Communication to designated inventor
Apr 24, 2013
Communication to designated inventor
Apr 24, 2013
Communication to designated inventor
Apr 24, 2013
Communication to designated inventor
Apr 24, 2013
Communication to designated inventor
Apr 24, 2013
Communication to designated inventor
Apr 24, 2013
Communication to designated inventor
Apr 10, 2013
(Electronic) Receipt
Apr 10, 2013
Converted Sequence Listing
Apr 10, 2013
Miscellaneous requests concerning client data
Apr 10, 2013
Request for entry into the European phase
Mar 27, 2013
Copy of the international preliminary report on patentability
Jan 18, 2013
Information on entry into European phase
Jun 7, 2012
Copy of the international search report
Jun 7, 2012
International publication of the international search report
Apr 13, 2012
Priority document (electronically transmitted)
Mar 15, 2012
Published international application - A2

EP2614369

EPIZYME

Application Number: EP11824247A
Filing Date: Sep 12, 2011
Status: Patent Maintained As Amended; Apr 25, 2025
Publication Date: May 28, 2025
External Links: Slate, Register , Google Patents

IP Verse

Inhibitors Of Human Ezh2, And Methods Of Use Thereof

Patent Summary

Patent Family

Patent Oppositions

Dossier Documents

EP2614369